{"id":1073,"date":"2017-02-02T11:44:47","date_gmt":"2017-02-02T02:44:47","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=1073"},"modified":"2017-02-02T11:44:47","modified_gmt":"2017-02-02T02:44:47","slug":"post-1073","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=1073","title":{"rendered":"\u7cd6\u8cea\u306e\u305f\u3063\u3077\u308a\u5165\u3063\u305f\u30b8\u30e5\u30fc\u30b9\u3092\u5973\u306e\u5b50\u306b\u98f2\u307e\u305b\u308b\u306e\u306f\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u304b\u3082\uff1f"},"content":{"rendered":"<p>\u7cd6\u8cea\u304c\u5165\u3063\u305f\u7518\u3044\u30b8\u30e5\u30fc\u30b9\u304c\u5973\u306e\u5b50\u306e\u521d\u6f6e\u5e74\u9f62\u3092\u65e9\u3081\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u30a2\u30e1\u30ea\u30ab\u306e\u30cf\u30fc\u30d0\u30fc\u30c9\u5927\u5b66\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u7802\u7cd6\u5165\u308a\u306e\u30b8\u30e5\u30fc\u30b9\u3092\u6bce\u65e51.5\u30b5\u30fc\u30d3\u30f3\u30b0\uff081\u30b5\u30fc\u30d3\u30f3\u30b0\u306f\u30b0\u30e9\u30b91\u676f\u30011\u7f36\u30011\u30dc\u30c8\u30eb\u306a\u3069\uff09\u4ee5\u4e0a\u98f2\u3093\u3067\u3044\u305f\u5973\u306e\u5b50\u306f\u3001\uff11\u9031\u9593\u306b2\u30b5\u30fc\u30d3\u30f3\u30b0\u4ee5\u4e0b\u306e\u5b50\u3068\u6bd4\u3079\u3066\u3001\u521d\u6f6e\u958b\u59cb\u5e74\u9f62\u304c2.7\u304b\u6708\u65e9\u304f\u306a\u3063\u305f\u305d\u3046\u3067\u3059\u3002\u30c0\u30a4\u30a8\u30c3\u30c8\u30bd\u30fc\u30c0\u3068\u30d5\u30eb\u30fc\u30c4\u30b8\u30e5\u30fc\u30b9\u306b\u306f\u3001\u521d\u6f6e\u5e74\u9f62\u3068\u306e\u3044\u304b\u306a\u308b\u95a2\u9023\u3082\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u305d\u3046\u3067\u3059\u3002\u3057\u304b\u3057\u30019\uff5e18.5\u6b73\u306e\u3069\u3053\u304b\u306e\u6642\u70b9\u30671\u65e5\u306b1.5\u30b5\u30fc\u30d3\u30f3\u30b0\u4ee5\u4e0a\u306e\u7802\u7cd6\u5165\u308a\u30b8\u30e5\u30fc\u30b9\u3092\u6bce\u65e5\u98f2\u3093\u3067\u3044\u305f\u5973\u306e\u5b50\u306f\u30011\u9031\u9593\u306b2\u30b5\u30fc\u30d3\u30f3\u30b0\u4ee5\u4e0b\u306e\u5973\u5b50\u3068\u6bd4\u3079\u3066\u3001\u305d\u306e\u7fcc\u6708\u306b\u521d\u6f6e\u304c\u59cb\u307e\u308b\u53ef\u80fd\u6027\u304c26%\u9ad8\u307e\u3063\u305f\u305d\u3046\u3067\u3059\u3002<\/p>\n<p>\u3053\u308c\u306f\u3001\u7802\u7cd6\u5165\u308a\u30b8\u30e5\u30fc\u30b9\u306e\u3088\u3046\u306a\u8840\u7cd6\u5024\u3092\u6025\u4e0a\u6607\u3055\u305b\u308b\u98df\u54c1\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u5faa\u74b0\u3059\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u6fc3\u5ea6\u304c\u6025\u901f\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002<span title=\"While the direct impact of SSB consumption on other hormones requires further investigation (DeLellis Henderson et al., 2007), insulin is known to down-regulate sex-hormone binding globulin and insulin-like growth factor binding protein-1 production (Holly et al\">\u7cd6\u8cea\u6442\u53d6\u3068\u4ed6\u306e\u30db\u30eb\u30e2\u30f3\u3078\u306e\u76f4\u63a5\u7684\u5f71\u97ff\u306b\u3064\u3044\u3066\u306f\u3055\u3089\u306a\u308b\u7814\u7a76\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u6027\u30db\u30eb\u30e2\u30f3\u7d50\u5408\u30b0\u30ed\u30d6\u30ea\u30f3\u304a\u3088\u3073\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea-1\u7523\u751f\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u751f\u7269\u5b66\u7684\u306b\u5229\u7528\u53ef\u80fd\u306a\u6027\u30db\u30eb\u30e2\u30f3\u304a\u3088\u3073IGF-1\u306e\u6fc3\u5ea6\u304c\u3088\u308a\u9ad8\u304f\u306a\u308a\u307e\u3059<\/span><span title=\"., 1989; Caprio, 1999), resulting in higher concentrations of bioavailable sex hormones and IGF-1.\">\u3002\u305d\u3046\u3057\u3066\u4f53\u5185\u3092<\/span><span title=\"Large alterations to circulating hormone concentrations have been compellingly linked to earlier menarche (Tam et al., 2006; Thankamony et al., 2012).\">\u5faa\u74b0\u3059\u308b\u30db\u30eb\u30e2\u30f3\u6fc3\u5ea6\u306e\u5927\u304d\u306a\u5909\u5316\u304c\u3001\u521d\u6f6e\u304c\u8d77\u3053\u308b\u3053\u3068\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u306e\u3067\u3059\u3002<\/span><\/p>\n<p>\u305f\u3063\u305f\u30012.7\u304b\u6708\u65e9\u304f\u306a\u3063\u305f\u3060\u3051\uff1f\u3068\u611f\u3058\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u521d\u6f6e\u5e74\u9f62\u304c\u65e9\u307e\u308b\u3053\u3068\u304c\u5f8c\u306b\u4e73\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3082\u91cd\u8981\u3067\u3042\u308b\u3068\u3053\u306e\u7814\u7a76\u3067\u306f\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u521d\u6f6e\u5e74\u9f62\u306e1\u6b73\u306e\u4f4e\u4e0b\u306f\u3001\u4e73\u304c\u3093\u306e\u30ea\u30b9\u30af\u30925\uff05\u5897\u52a0\u3055\u305b\u308b\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u72e9\u731f\u63a1\u96c6\u6c11\u306e\u521d\u6f6e\u5e74\u9f62\u306f17\u6b73\u524d\u5f8c\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u306e\u5973\u306e\u5b50\u306f\u521d\u6f6e\u304c\u65e9\u3059\u304e\u307e\u3059\u3002\u3053\u306e\u3053\u3068\u3068\u4e73\u304c\u3093\u60a3\u8005\u306e\u5897\u52a0\u306f\u975e\u5e38\u306b\u95a2\u9023\u304c\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n<p>\u7802\u7cd6\u5165\u308a\u306e\u30b8\u30e5\u30fc\u30b9\u3060\u3051\u3067\u3053\u308c\u3060\u3051\u30ea\u30b9\u30af\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u4eca\u306e\u98df\u4e8b\u3084\u9593\u98df\u306f\u7cd6\u8cea\u3060\u3089\u3051\u306a\u306e\u3067\u3001\u3082\u3063\u3068\u521d\u6f6e\u306e\u5e74\u9f62\u3092\u65e9\u304f\u3059\u308b\u30ea\u30b9\u30af\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u89aa\u304c\u8003\u3048\u308c\u3070\u56de\u907f\u3067\u304d\u308b\u3053\u3068\u3067\u3059\u3002\u30b8\u30e5\u30fc\u30b9\u3092\u5168\u304f\u3042\u3052\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u306a\u304f\u3001\u3068\u304d\u3069\u304d\u5c11\u91cf\u305a\u3064\u3001\u7518\u3044\u304a\u83d3\u5b50\u3082\u3068\u304d\u3069\u304d\u5c11\u91cf\u305a\u3064\u3002\u5b50\u4f9b\u304c\u304b\u308f\u3044\u3044\u306e\u306a\u3089\u3001\u5b50\u4f9b\u306b\u3082\u7cd6\u8cea\u5236\u9650\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002<\/p>\n<p><a href=\"http:\/\/www.e-hon.ne.jp\/bec\/SA\/Detail?refShinCode=0100000000000033523498&amp;Sza_id=A0\" target=\"_blank\">\u300c\u7cd6\u8cea\u5236\u9650\u300d\u304c\u5b50\u4f9b\u3092\u6551\u3046<\/a>\u3001\u3082\u662f\u975e\u8aad\u3093\u3067\u307f\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/academic.oup.com\/humrep\/article\/30\/3\/675\/661239\/Sugar-sweetened-beverage-consumption-and-age-at\" target=\"_blank\">\u539f\u6587\u306f\u3053\u3053\u3067\u3059\u3002Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7cd6\u8cea\u304c\u5165\u3063\u305f\u7518\u3044\u30b8\u30e5\u30fc\u30b9\u304c\u5973\u306e\u5b50\u306e\u521d\u6f6e\u5e74\u9f62\u3092\u65e9\u3081\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 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