{"id":1101,"date":"2017-02-16T15:10:30","date_gmt":"2017-02-16T06:10:30","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=1101"},"modified":"2020-01-10T08:41:38","modified_gmt":"2020-01-09T23:41:38","slug":"post-1101","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=1101","title":{"rendered":"\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607"},"content":{"rendered":"<p>\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3044\u308b\u3068\u8840\u6db2\u691c\u67fb\u3067\u6b21\u3005\u3068\u30c7\u30fc\u30bf\u304c\u6b63\u5e38\u5316\u3057\u3066\u3044\u304f\u306e\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4e0a\u6607\u3057\u3066\u3057\u307e\u3044\u3001\u7570\u5e38\u5024\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3046\u3044\u3046\u79c1\u3082LDL\u304c\u9ad8\u5024\u3067\u3059\u3002\u3044\u3064\u306e\u9593\u306b\u304bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u300c\u60aa\u7389\u300d\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u300c\u5584\u7389\u300d\u3068\u3044\u3046\u6d17\u8133\u304c\u3055\u308c\u3066\u3044\u307e\u3059\u306e\u3067\u3001LDL\u304c\u4e0a\u6607\u3059\u308b\u3068\u975e\u5e38\u306b\u6c17\u306b\u306a\u308b\u65b9\u3082\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u3057\u3001\u533b\u5e2b\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u5024\u3068\u3044\u3046\u7406\u7531\u3060\u3051\u3067\u3001\u30b9\u30bf\u30c1\u30f3\u3092\u51e6\u65b9\u3057\u3088\u3046\u3068\u3057\u307e\u3059\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u3082\u3046\u3059\u3067\u306b\u308f\u304b\u3063\u3066\u3044\u308b\u901a\u308a\u3001LDL\u306b\u3082\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002LDL\u305d\u306e\u3082\u306e\u306f\u672b\u68a2\u306e\u7d30\u80de\u304c\u7d30\u80de\u819c\u3092\u4f5c\u3063\u305f\u308a\u3059\u308b\u6750\u6599\u3092\u904b\u3076\u3001\u3068\u3044\u3046\u91cd\u8981\u306a\u5f79\u5272\u304c\u3042\u308a\u3001\u975e\u5e38\u306b\u5927\u5207\u3067\u4e0d\u53ef\u6b20\u306a\u3082\u306e\u3067\u3059\u3002\u3060\u304b\u3089LDL\u3068\u3044\u3046\u3060\u3051\u3067\u60aa\u7389\u3068\u547c\u3076\u306e\u306f\u975e\u5e38\u306b\u30ec\u30d9\u30eb\u306e\u4f4e\u3044\u8a71\u306b\u306a\u308a\u307e\u3059\u3002\u4eba\u4f53\u306b\u60aa\u5f71\u97ff\u306a\u306e\u306fLDL\u306e\u4e2d\u3067\u3082\u5c0f\u7c92\u5b50LDL\u3067\u3059\u3002\u3053\u306e\u5c0f\u7c92\u5b50LDL\u306f\u9178\u5316LDL\u306b\u5909\u5316\u3057\u3084\u3059\u304f\u3001\u52d5\u8108\u786c\u5316\u306e\u539f\u56e0\u3001\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u304f\u3059\u308b\u3082\u306e\u306a\u306e\u3067\u3059\u3002<\/p>\n<p>\u3067\u306f\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3068\u3069\u3046\u3057\u3066LDL\u304c\u9ad8\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u73fe\u5728LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u76f4\u63a5\u6e2c\u5b9a\u3059\u308b\u5834\u5408\u3068\u3001\u8a08\u7b97\u5f0f\u3067\u6c42\u3081\u308b\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u76f4\u63a5\u6cd5\u306f\u7cbe\u5ea6\u304c\u3042\u307e\u308a\u9ad8\u304f\u306a\u304f\u3001\u8a08\u7b97\u5f0f\u306e\u65b9\u304c\u4e00\u822c\u7684\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u901a\u5e38<span lang=\"EN-US\" style=\"margin: 0px; color: black; font-family: 'Helvetica',sans-serif; font-size: 12pt;\">Friedwald<\/span>\u306e\u5f0f\u3092\u4f7f\u3044\u307e\u3059\u3002<\/p>\n<p align=\"center\"><b><span lang=\"EN-US\" style=\"margin: 0px; color: black; font-family: 'Helvetica',sans-serif; font-size: 12pt;\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb= [\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb] \u2013 [HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb] \u2013 [\u4e2d\u6027\u8102\u80aa]\u00f75<\/span><\/b><\/p>\n<p style=\"text-align: left;\" align=\"center\">\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304b\u3089HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3068\u3001\u4e2d\u6027\u8102\u80aa\u5024\u306e\uff15\u5206\u306e\uff11\u3092\u5f15\u3044\u305f\u5024\u304cLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u8a08\u7b97\u5f0f\u306f\u3001\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u3068\u3044\u3046\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u304c\u8840\u6e05\u4e2d\u306b\u5b58\u5728\u3057\u306a\u3044\u5834\u5408\uff08\u3064\u307e\u308a\u98df\u5f8c\u3067\u306f\u306a\u304f\u7a7a\u8179\u6642\uff09\u3001\u8840\u6e05\u306e\u4e2d\u6027\u8102\u80aa\uff08\u30c8\u30ea\u30b0\u30ea\u30bb\u30e9\u30a4\u30c9\uff09\u306e\u307b\u3068\u3093\u3069\u304cVLDL\u306b\u5b58\u5728\u3057\u3001\u305d\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u4e2d\u6027\u8102\u80aa\u6bd4\u304c\u307b\u307c1\uff1a5\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u3057\u304b\u3057\u3001\u672c\u5f53\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u4e2d\u6027\u8102\u80aa\u6bd4\u304c\u307b\u307c1\uff1a5\u3067\u3042\u308b\u304b\u3068\u3044\u3046\u3068\u3001\u5b9f\u969b\u306b\u306f\u7570\u306a\u308a\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u304c\uff14\uff10\uff10\u3092\u8d85\u3048\u308b\u3068\u3053\u306e\u5f0f\u306e\u7cbe\u5ea6\u306f\u4e0b\u304c\u308b\u306e\u3067\u4f7f\u3048\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u5b9f\u969b\u306b\u306f\u3082\u3063\u3068\u4f4e\u3044\u5024\u3067\u30821\uff1a5\u3067\u306f\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u6975\u7aef\u306a\u4f8b\u3067\u793a\u3059\u3068\u3001\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u304f\u306a\u308a\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u4e2d\u6027\u8102\u80aa\u6bd4\u304c1\uff1a\uff11\uff10\u3067\u3042\u308b\u3068\u3059\u308b\u3068\u3001\u672c\u6765\u306f\u4e2d\u6027\u8102\u80aa\u306e10\u5206\u306e1\u304cVLDL\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306a\u308b\u306f\u305a\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u8a08\u7b97\u3067\u306f5\u5206\u306e1\u306b\u3057\u304b\u306a\u3089\u306a\u3044\u306e\u3067\u3001\u7d50\u679c\u7684\u306b\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u304f\u306a\u308a\u307e\u3059\u3002\u9006\u306b\u4e2d\u6027\u8102\u80aa\u304c\u975e\u5e38\u306b\u4f4e\u304f\u306a\u308a\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u4e2d\u6027\u8102\u80aa\u6bd4\u304c1\uff1a\uff12\u3068\u3044\u3046\u72b6\u6cc1\u3092\u60f3\u5b9a\u3059\u308b\u3068\u3001\u672c\u6765\u306f\u4e2d\u6027\u8102\u80aa\u306e2\u5206\u306e1\u304cVLDL\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306a\u308b\u306f\u305a\u306a\u306e\u306b\u3001\u305d\u308c\u304c5\u5206\u306e\uff11\u3067\u8a08\u7b97\u3055\u308c\u3066\u3057\u307e\u3044\u3001\u7d50\u679c\u7684\u306b\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9ad8\u304f\u51fa\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u3082\u3063\u3068\u3082\u7cbe\u5ea6\u304c\u9ad8\u3044\u306e\u306f\u4e2d\u6027\u8102\u80aa\u5024\u304c150\uff5e300\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002400\u3092\u8d85\u3048\u308b\u5834\u5408\u3060\u3051\u3067\u306a\u304f100\u672a\u6e80\u306e\u5834\u5408\u3082\u3053\u306e\u5f0f\u306b\u306f\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u3002100\u672a\u6e80\u3067\u306f\u6709\u610f\u306bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3092\u904e\u5927\u306b\u8a55\u4fa1\u3057\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3068\u307b\u3068\u3093\u3069\u306e\u4eba\u304c\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3069\u3093\u3069\u3093\u4e0b\u304c\u308a\u307e\u3059\u3002\u79c1\u306f\u4f4e\u3044\u6642\u306740\u53f0\u3067\u3059\u3002HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9006\u306b\u3069\u3093\u3069\u3093\u4e0a\u6607\u3057\u307e\u3059\u3002\u79c1\u306f80\uff5e90\u53f0\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u3067\u3059\u304b\u3089\u3001\u3042\u307e\u308aLDL\u306e\u5024\u306b\u4e00\u559c\u4e00\u6182\u3057\u306a\u3044\u3067\u4e0b\u3055\u3044\u3002\u7cd6\u8cea\u5236\u9650\u98df\u3067\u306f\u3042\u307e\u308a\u610f\u5473\u304c\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\"><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"1103\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=1103\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?fit=573%2C403&amp;ssl=1\" data-orig-size=\"573,403\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;\\u6e05\\u6c34\\u6cf0\\u884c&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1487251458&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\uff34\uff27\u3068\uff2c\uff24\uff2c\u306e\u95a2\u4fc2\u56f3\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?fit=300%2C211&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?fit=573%2C403&amp;ssl=1\" class=\"alignnone size-medium wp-image-1103\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?resize=300%2C211\" alt=\"\" width=\"300\" height=\"211\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?resize=300%2C211&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/8486a4285eb5219d2176d4eff63155db.jpg?w=573&amp;ssl=1 573w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p style=\"text-align: left;\" align=\"center\"><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"1104\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=1104\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?fit=465%2C405&amp;ssl=1\" data-orig-size=\"465,405\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;\\u6e05\\u6c34\\u6cf0\\u884c&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1487251500&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\uff28\uff24\uff2c\u3068\uff2c\uff24\uff2c\u306e\u95a2\u4fc2\u56f3\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?fit=300%2C261&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?fit=465%2C405&amp;ssl=1\" class=\"alignnone size-medium wp-image-1104\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?resize=300%2C261\" alt=\"\" width=\"300\" height=\"261\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?resize=300%2C261&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/d4683760a94deb97157c8508821aa2ad.jpg?w=465&amp;ssl=1 465w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p style=\"text-align: left;\" align=\"center\">\uff08\u56f3\u306fAtherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk.<\/p>\n<p style=\"text-align: left;\" align=\"center\">M A Austin, M C King, K M Vranizan and R M Krauss\u00a0\u00a0\u00a0 Circulation. 1990;82:495-506\u3088\u308a\u629c\u7c8b\uff09<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u4e0a\u306e\u56f3\u306f\u4e2d\u6027\u8102\u80aa\u3068LDL\u306e\u6027\u72b6\u3092\u793a\u3057\u3001\u4e0b\u306e\u56f3\u306fHDL\u3068LDL\u306e\u6027\u72b6\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002Phenotype A\u00a0\u306f\u5927\u304d\u306a\u6d6e\u904a\u6027\u306e\u7121\u5bb3\u306aLDL\u7c92\u5b50\u304b\u3089\u306a\u308bLDL\u3067\u3042\u308a\u3001Phenotype B\u306f\u5c0f\u3055\u306a\u3001\u9ad8\u5bc6\u5ea6\u306e\u60aa\u3044LDL\u7c92\u5b50\u304b\u3089\u306a\u308bLDL\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u4e2d\u6027\u8102\u80aa\u304c\uff16\uff10\u4ee5\u4e0b\u3067\u3042\u308c\u307075\uff05\u306fPhenotype A\u00a0\u3068\u3044\u3046\u826f\u3044LDL\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa\u304c100\u3092\u8d85\u3048\u308b\u3068Phenotype A\u00a0\u3068Phenotype B\u306f\u9006\u8ee2\u3057\u3001\u4e2d\u6027\u8102\u80aa\u306e\u6b63\u5e38\u5024\u306e150\u672a\u6e80\u4ed8\u8fd1\u3067\u306f\u307b\u3068\u3093\u3069\u5927\u304d\u306a\u826f\u3044LDL\u306f\u5b58\u5728\u3057\u306a\u3044\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u540c\u69d8\u306bHDL\u306e\u5024\u3067\u3082\u6b63\u5e38\u5024\u306e40\u3092\u5883\u306bPhenotype A\u00a0\u3068Phenotype B\u306f\u9006\u8ee2\u3057\u307e\u3059\u3002HDL\u304c60\u3082\u3042\u308c\u3070\u307b\u3068\u3093\u3069\u306f\u826f\u3044LDL\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u3064\u307e\u308a\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3092\u898b\u305f\u3068\u304d\u306b\u3001LDL\u306e\u4e2d\u8eab\u3092\u8003\u3048\u308b\u3068\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3067\u304d\u308b\u9650\u308a\u4f4e\u304f\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u300c\u5584\u7389\u300dLDL\u304c\u3044\u3063\u3071\u3044\u5b58\u5728\u3059\u308b\u306e\u3067\u3059\u3002\u5024\u3060\u3051\u306b\u7ffb\u5f04\u3055\u308c\u3066\u306f\u30c0\u30e1\u3067\u3059\u3002\u533b\u5e2b\u3067\u3059\u3089\u7ffb\u5f04\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u2026<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u305d\u3053\u3067\u3001\u6700\u8fd1\u306f\u4e2d\u6027\u8102\u80aa\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4\uff08\u4ee5\u4e0bTG \/ HDL-C\u6bd4\u3068\u8868\u3057\u307e\u3059\uff09\u3092\u5fc3\u81d3\u75c5\u306e\u30ea\u30b9\u30af\u306e\u6307\u6a19\u306b\u3057\u3088\u3046\u3068\u3044\u3046\u8003\u3048\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">TG \/ HDL-C\u6bd4\u306f\u3001\u51a0\u52d5\u8108\u75be\u60a3\u306e\u767a\u751f\u7387\u304a\u3088\u3073\u7a0b\u5ea6\u3068\u5f37\u304f\u76f8\u95a2\u3059\u308b\u3053\u3068\u304c\u3001\u591a\u304f\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u5224\u660e\u3057\u3066\u3044\u307e\u3059\u3002<span title=\"One study\u00a0found\u00a0that a TG\/HDL-C ratio above 4 was the most powerful independent predictor of developing coronary artery disease. \">\u3042\u308b\u7814\u7a76\u3067\u306f\u3001TG \/ HDL-C\u6bd4\u304c4\u3088\u308a\u5927\u304d\u3044\u3053\u3068\u304c\u3001\u51a0\u52d5\u8108\u75be\u60a3\u767a\u75c7\u306e\u6700\u3082\u5f37\u529b\u306a\u72ec\u7acb\u3057\u305f\u4e88\u6e2c\u56e0\u5b50\u3067\u3042\u308b\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p style=\"text-align: left;\" align=\"center\"><span title=\"One study\u00a0found\u00a0that a TG\/HDL-C ratio above 4 was the most powerful independent predictor of developing coronary artery disease. \">\u7406\u60f3\u306eTG \/ HDL-C\u6bd4\u306f\u3068\u3044\u3046\u3068<\/span><\/p>\n<p style=\"text-align: left;\" align=\"center\"><span title=\"One study\u00a0found\u00a0that a TG\/HDL-C ratio above 4 was the most powerful independent predictor of developing coronary artery disease. \">2\u672a\u6e80\u306eTG \/ HDL-C\u6bd4\u304c\u7406\u60f3\u7684<br \/>\n4\u4ee5\u4e0a\u306eTG \/ HDL-C\u6bd4\u304c\u9ad8\u3059\u304e\u308b<br \/>\n6\u4ee5\u4e0a\u306eTG \/ HDL-C\u6bd4\u306f\u3055\u3089\u306b\u5927\u304d\u306a\u5371\u967a\uff01<\/span><\/p>\n<p style=\"text-align: left;\" align=\"center\">\u3061\u306a\u307f\u306b\u79c1\u306e\u6700\u65b0\u306eTG \/ HDL-C\u6bd4\u306f0.7\u3067\u3059\uff01<\/p>\n<p style=\"text-align: left;\" align=\"center\">\u307e\u305f\u3042\u308b\u7814\u7a76\u3067\u306fTG \/ HDL-C\u6bd4\u306fLDL\u306e\u7c92\u5b50\u306e\u30b5\u30a4\u30ba\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3053\u3068\u304c\u898b\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002 <span title=\"One study found that 79% of individuals with a ratio above 3.8 had a preponderance of small dense LDL particles, whereas 81% of those with a ratio below 3.8 had a preponderance of large buoyant particles. \">3.8\u3092\u8d85\u3048\u308bTG \/ HDL-C\u6bd4\u3067\u306f79\uff05\u304c\u5c0f\u3055\u306a\u9ad8\u5bc6\u5ea6\u306eLDL\u3092\u512a\u52e2\u3068\u3057\u30013.8\u672a\u6e80\u306eTG \/ HDL-C\u6bd4\u3067\u306f81\uff05\u304c\u5927\u304d\u306a\u6d6e\u904a\u6027\u306eLDL\u3092\u512a\u52e2\u3068\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u306e\u3067\u3059\u3002<\/span><\/p>\n<p style=\"text-align: left;\" align=\"center\">\u65e5\u672c\u306e\u5ca1\u5c71\u5927\u5b66\u306e\u7814\u7a76\u3067\u306fTG \/ HDL-C\u6bd4\u304c3.03\u4ee5\u4e0a\u3067\u306f\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u3092\u60f9\u8d77\u3057\u3084\u3059\u3044\u51a0\u52d5\u8108\u306e\u30cf\u30a4\u30ea\u30b9\u30af\u30d7\u30e9\u30fc\u30af\u304c\u6709\u610f\u306b\u5897\u52a0\u3059\u308b\u305d\u3046\u3067\u3059\u3002<\/p>\n<p style=\"text-align: left;\" align=\"center\">TG \/ HDL-C\u6bd4\u304c\u9ad8\u3044\u3068\u5f53\u7136\u4e2d\u6027\u8102\u80aa\u304c\u901a\u5e38\u3088\u308a\u3082\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u3082\u8102\u8cea\u306a\u306e\u3067\u3001\u8840\u6db2\u4e2d\u306f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u306b\u3088\u3063\u3066\u904b\u3070\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u307b\u3068\u3093\u3069\u306f\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u3068VLDL\u306b\u3088\u3063\u3066\u904b\u3070\u308c\u307e\u3059\u3002\u305d\u306e\u6642\u306b\u8d77\u3053\u308b\u3053\u3068\u306f\u3001<span title=\"What happens\u00a0under these circumstances is an interchange of lipids between lipoproteins.\">\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u9593\u306e\u8102\u8cea\u306e\u4ea4\u63db\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa<\/span><span title=\"TG\u00a0are moved from VLDL into LDL and HDL in exchange for cholesteryl ester.\">\u306f\u30b3\u30ec\u30b9\u30c6\u30ea\u30eb\u30a8\u30b9\u30c6\u30eb\u306e\u4ee3\u308f\u308a\u306bVLDL\u304b\u3089LDL\u304a\u3088\u3073HDL\u306b\u79fb\u884c\u3057\u307e\u3059\u3002\u305d<\/span><span title=\"The result is that LDL and HDL particles become cholesterol poor and rich in TG.\">\u306e\u7d50\u679c\u3001LDL\u304a\u3088\u3073HDL\u306e\u7c92\u5b50\u306f\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u304f\u4e2d\u6027\u8102\u80aa\u304c\u8c4a\u5bcc\u306a\u72b6\u614b\u306b\u306a\u308a\u307e\u3059\u3002<\/span><span title=\"Then, when TG\u00a0are removed from these particles, which usually\u00a0is the case, the particles shrink and become smaller as they\u2019re\u00a0only transporting small amounts of cholesterol.\">\u305d\u3057\u3066\u3001\u4e2d\u6027\u8102\u80aa\u304c\u3053\u308c\u3089\u306e\u7c92\u5b50\u304b\u3089\u9664\u53bb\u3055\u308c\u308b\u3068\u3001\u901a\u5e38\u3088\u308a\u3082\u5c11\u91cf\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3057\u304b\u6301\u3061\u5408\u308f\u305b\u3066\u3044\u306a\u3044\u306e\u3067\u3001\u7c92\u5b50\u306f\u53ce\u7e2e\u3057\u3066\u5c0f\u3055\u304f\u306a\u308a\u307e\u3059\u3002<\/span><span title=\"This explains the relationship between high TG\/HDL-C ratio and the number of\u00a0small LDL particles. \">\u3053\u306e\u3053\u3068\u306b\u3088\u308a\u3001\u9ad8\u3044TG \/ HDL-C\u6bd4\u3068\u5c0f\u3055\u306aLDL\u7c92\u5b50\u306e\u6570\u3068\u306e\u9593\u306e\u95a2\u4fc2\u304c\u8aac\u660e\u3067\u304d\u307e\u3059\u3002<br \/>\n<\/span><\/p>\n<p style=\"text-align: left;\" align=\"center\">\u7cd6\u8cea\u5236\u9650\u306f\u4e2d\u6027\u8102\u80aa\u3092\u4e0b\u3052\u3066\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4e0a\u6607\u3055\u305b\u308b\u306e\u306b\u975e\u5e38\u306b\u6709\u7528\u3067\u3059\u3002\u305f\u3060\u5358\u306bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3070\u304b\u308a\u3092\u898b\u3066\u3082\u3001\u5fc3\u8840\u7ba1\u7cfb\u306e\u75c5\u6c17\u3092\u9632\u3050\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002LDL\u304c\u9ad8\u3044\u3060\u3051\u3067\u30b9\u30bf\u30c1\u30f3\u3092\u51e6\u65b9\u3057\u3088\u3046\u3068\u3059\u308b\u533b\u5e2b\u306b\u4f1a\u3063\u305f\u306a\u3089\u3001\u305d\u306e\u5834\u3092\u7acb\u3061\u53bb\u308b\u9078\u629e\u3082\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002<\/p>\n<p align=\"center\">\n<p style=\"text-align: left;\" align=\"center\">\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=2571\" target=\"_blank\" rel=\"noopener noreferrer\">\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u66072\u3000\u4eee\u8aac<\/a>\u300d\u3082\u4e00\u7dd2\u306b\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n<p align=\"center\">\n","protected":false},"excerpt":{"rendered":"<p>\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3044\u308b\u3068\u8840\u6db2\u691c\u67fb\u3067\u6b21\u3005\u3068\u30c7\u30fc\u30bf\u304c\u6b63\u5e38\u5316\u3057\u3066\u3044\u304f\u306e\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4e0a\u6607\u3057\u3066\u3057\u307e\u3044\u3001\u7570\u5e38\u5024\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3046\u3044\u3046\u79c1\u3082LDL\u304c\u9ad8\u5024\u3067\u3059\u3002\u3044\u3064\u306e\u9593\u306b\u304bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u300c\u60aa\u7389\u300d\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed<\/p>\n","protected":false},"author":1,"featured_media":1102,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[149,8,145,146,15,144],"tags":[],"class_list":["post-1101","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-statin","category-8","category-ldl","category-hdl","category-15","category-cholesterol","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/02\/76e7b5120b4719b732704b1c70c559a9_s.jpg?fit=640%2C480&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-hL","jetpack-related-posts":[{"id":2861,"url":"https:\/\/promea2014.com\/blog\/?p=2861","url_meta":{"origin":1101,"position":0},"title":"\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u66074\u3000\u4e2d\u6027\u8102\u80aa\u5024\u304c\u975e\u5e38\u306b\u4f4e\u3044\u5834\u5408\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u8a08\u7b97\u5f0f","author":"Dr.Shimizu","date":"2017\u5e7410\u670831\u65e5","format":false,"excerpt":"\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607\u300d\u3067\u793a\u3057\u305f\u3088\u3046\u306b\u3001\u5f93\u6765\u306eFriedwald\u306e\u5f0f\uff1a 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