{"id":11339,"date":"2020-03-10T20:19:08","date_gmt":"2020-03-10T11:19:08","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=11339"},"modified":"2020-03-10T20:19:08","modified_gmt":"2020-03-10T11:19:08","slug":"post-11339","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=11339","title":{"rendered":"\u4eba\u5de5\u7518\u5473\u6599\u306f\u30d6\u30c9\u30a6\u7cd6\u306b\u5bfe\u3059\u308b\u8840\u7cd6\u5024\u304a\u3088\u3073\u30db\u30eb\u30e2\u30f3\u53cd\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3000\u305d\u306e2"},"content":{"rendered":"

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u4eba\u5de5\u7518\u5473\u6599\u306f\u30d6\u30c9\u30a6\u7cd6\u306b\u5bfe\u3059\u308b\u8840\u7cd6\u5024\u304a\u3088\u3073\u30db\u30eb\u30e2\u30f3\u53cd\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3000\u305d\u306e1<\/a>\u300d\u3067\u306f\u3001\u80a5\u6e80\u306e\u4eba\u306b\u304a\u3044\u3066\u3001\u4eba\u5de5\u7518\u5473\u6599\u306f\u751f\u7406\u7684\u306b\u6d3b\u6027\u3092\u793a\u3057\u3001\u30d6\u30c9\u30a6\u7cd6\u306b\u3088\u308b\u53cd\u5fdc\u3092\u4fee\u98fe\u3057\u3001\u8840\u7cd6\u5024\u3092\u4e0a\u3052\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5897\u52a0\u3092\u62db\u304f\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u7cd6\u5c3f\u75c5\u3084\u6709\u610f\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u6709\u3057\u3066\u3044\u308b\u4eba\u306f\u9664\u5916\u3055\u308c\u3001\u6b63\u5e38\u4f53\u91cd\u306e\u4eba\u3068\u80a5\u6e80\u306e\u4eba\uff08\u5e73\u5747BMI37.7\uff09\u3067\u300175g\u306e\u7d4c\u53e3\u30d6\u30c9\u30a6\u7cd6\u8ca0\u8377\u8a66\u9a13\uff08OGTT\uff09\u306e\u524d\u306b\u6c34\u307e\u305f\u306f\u4eba\u5de5\u7518\u5473\u6599\u306e\u30b9\u30af\u30e9\u30ed\u30fc\u30b960ml\uff0848mg\uff09\u3092\u98f2\u3080\u304b\u30015\u79d2\u9593\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u3092\u53e3\u306b\u542b\u3093\u3067\u5410\u304d\u51fa\u3059\u304b\u306e\u3069\u308c\u304b\u3092\u884c\u3044\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

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\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u306e\u6442\u53d6\u3067\u306f\u4e21\u65b9\u306e\u4f53\u91cd\u7fa4\u3067\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u5897\u52a0\u5206\u306e\u66f2\u7dda\u4e0b\u9762\u7a4d\u304c30\uff05\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u30d4\u30fc\u30af\u306f\u3001\u80a5\u6e80\u7fa4\u306e\u65b9\u304c\u6b63\u5e38\u4f53\u91cd\u7fa4\u3088\u308a\u3082\u4f4e\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u4e00\u65b9\u30a4\u30f3\u30b9\u30ea\u30f3\u304a\u3088\u3073C\u30da\u30d7\u30c1\u30c9\u306e\u30d4\u30fc\u30af\u5024\u3001\u306a\u3089\u3073\u306b\u5897\u52a0\u5206\u306e\u66f2\u7dda\u4e0b\u9762\u7a4d\u306f\u3001\u80a5\u6e80\u306e\u65b9\u304c\u6b63\u5e38\u4f53\u91cd\u306e\u4eba\u3088\u308a\u6709\u610f\u306b\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u6c34\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u5410\u304d\u51fa\u3057\u3067\u306f\u3001\u4e21\u65b9\u306e\u4f53\u91cd\u7fa4\u3067OGTT\u306e\u6700\u521d\u306e1\u6642\u9593\u4ee5\u5185\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002<\/p>\n

\u6b63\u5e38\u4f53\u91cd\u3067\u306f\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u6442\u53d6\u306f\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u8ca0\u8377\u5f8c\u6700\u521d\u306e40\u5206\u9593\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u304c\u3001\u80a5\u6e80\u3067\u306e\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u6442\u53d6\u306f\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u8ca0\u8377\u5f8c\u306e\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u5410\u304d\u51fa\u3057\uff0810\u5206\u300130\u301c60\u5206\uff09\u304a\u3088\u3073\u6c34\u306e100\u301c140\u5206\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u6709\u610f\u306b\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u6b63\u5e38\u4f53\u91cd<\/th>\n\u80a5\u6e80<\/th>\n<\/tr>\n
\u6c34<\/th>\n\u30b9\u30af\u30e9\u30ed\u30fc\u30b9<\/th>\n\u5410\u304d\u51fa\u3057<\/th>\n\u6c34<\/th>\n\u30b9\u30af\u30e9\u30ed\u30fc\u30b9<\/th>\n\u5410\u304d\u51fa\u3057<\/th>\n<\/tr>\n<\/thead>\n
\u30d4\u30fc\u30af\u306b\u304a\u3051\u308b\u5897\u52a0\u5206<\/b><\/td>\n<\/tr>\n
\u30b0\u30eb\u30b3\u30fc\u30b9\uff08mmol\/L\uff09<\/td>\n5.7\u00b10.4<\/td>\n5.4\u00b10.5<\/td>\n5.5\u00b10.4<\/td>\n4.4\u00b10.4<\/td>\n4.7\u00b10.4<\/td>\n4.5\u00b10.4<\/td>\n<\/tr>\n
\u30a4\u30f3\u30b9\u30ea\u30f3\uff08pmol\/L\uff09<\/td>\n683\u00b1130<\/td>\n548\u00b191<\/td>\n590\u00b1115<\/td>\n1062\u00b1124<\/td>\n1193\u00b1171<\/td>\n1041\u00b1184<\/td>\n<\/tr>\n
C-\u30da\u30d7\u30c1\u30c9\uff08nmol\/L\uff09<\/td>\n2.8\u00b10.3<\/td>\n2.6\u00b10.3<\/td>\n2.8\u00b10.3<\/td>\n3.7\u00b10.4<\/td>\n3.9\u00b10.4<\/td>\n3.6\u00b10.3<\/td>\n<\/tr>\n
GIP\uff08pmol\/L\uff09<\/td>\n49.5\u00b16.8<\/td>\n45.0\u00b15.9<\/td>\n48.5\u00b15.5<\/td>\n61.9\u00b14.0<\/td>\n59.6\u00b15.2<\/td>\n56.0\u00b14.4<\/td>\n<\/tr>\n
\u5897\u52a0\u5206\u66f2\u7dda\u4e0b\u9762\u7a4d<\/b><\/td>\n<\/tr>\n
\u30b0\u30eb\u30b3\u30fc\u30b9\uff08mmol\/L\uff09\u30fb300\u5206<\/td>\n470\u00b156<\/td>\n560\u00b166<\/td>\n491\u00b160<\/td>\n380\u00b155<\/td>\n455\u00b148<\/td>\n455\u00b159<\/td>\n<\/tr>\n
\u30a4\u30f3\u30b9\u30ea\u30f3\uff0810\u00a02<\/sup> pmol \/ L\uff09\u30fb300\u5206<\/td>\n654\u00b1131<\/td>\n607\u00b1102<\/td>\n597\u00b1106<\/td>\n1195\u00b1177<\/td>\n1400\u00b1241<\/td>\n1282\u00b1257<\/td>\n<\/tr>\n
C-\u30da\u30d7\u30c1\u30c9\uff08nmol \/ L\uff09\u30fb300\u5206<\/td>\n375\u00b140<\/td>\n394\u00b143<\/td>\n375\u00b145<\/td>\n502\u00b154<\/td>\n565\u00b147<\/td>\n541\u00b143<\/td>\n<\/tr>\n
GIP\uff0810\u00a02<\/sup>\u00a0pmol \/ L\uff09\u30fb300\u5206<\/td>\n67\u00b111<\/td>\n62\u00b110<\/td>\n64\u00b17<\/td>\n79\u00b16<\/td>\n74\u00b15<\/td>\n72\u00b17<\/td>\n<\/tr>\n
\u30b0\u30eb\u30b3\u30fc\u30b9\u52d5\u614b<\/b><\/td>\n<\/tr>\n
\u30d4\u30fc\u30af<\/b><\/td>\n<\/tr>\n
\u7dcf\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387
\n\uff08\u00b5mol \/ min\uff09<\/td>\n		2274\u00b1147<\/td>\n2313\u00b1242<\/td>\n2071\u00b1253<\/td>\n2576\u00b1206<\/td>\n2672\u00b1198<\/td>\n2552\u00b1229<\/td>\n<\/tr>\n
\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\uff08\u00b5mol \/ min\uff09<\/td>\n2565\u00b1109<\/td>\n2436\u00b1154<\/td>\n2482\u00b1203<\/td>\n3159\u00b1217<\/td>\n3169\u00b1225<\/td>\n3094\u00b1244<\/td>\n<\/tr>\n
AUC<\/b><\/td>\n<\/tr>\n
\u7dcf\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387
\n\uff0810\u00a02<\/sup>\u00a0mol \/ min\uff09\u30fb300\u5206<\/td>\n		3947\u00b1269<\/td>\n3920\u00b1296<\/td>\n4348\u00b1315<\/td>\n3664\u00b185<\/td>\n3580\u00b191<\/td>\n3436\u00b195<\/td>\n<\/tr>\n
\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\uff0810 2<\/sup>\u00a0mol \/ min\uff09\u30fb300\u5206<\/td>\n2884\u00b1143<\/td>\n2967\u00b169<\/td>\n3405\u00b1185<\/td>\n2910\u00b190<\/td>\n2928\u00b198<\/td>\n2780\u00b187<\/td>\n<\/tr>\n
\u5faa\u74b0\u4e2d\u306b\u73fe\u308c\u308b\u7dcf\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\uff05\uff0875 g\u306e\u3046\u3061\uff09<\/td>\n69.6\u00b13.5<\/td>\n71.3\u00b11.7<\/td>\n78.9\u00b14.7<\/td>\n69.7\u00b12.5<\/td>\n71.2\u00b12.8<\/td>\n71.3\u00b13.1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\uff08\u65e5\u672c\u306e\u5358\u4f4d\u306b\u3059\u308b\u306b\u306f\u30b0\u30eb\u30b3\u30fc\u30b9\u306f\u00d718\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u00f71000\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002\uff09<\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u4e0a\u304c\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u3067\u3059\u3002\u3057\u305f\u304c\u3001\u5185\u56e0\u6027\u30b0\u30eb\u30b3\u30fc\u30b9\u7523\u751f\u7387\u3067\u3059\u3002\u7d2b\u304c\u6b63\u5e38\u4f53\u91cd\u3001\u9752\u304c\u80a5\u6e80\u3067\u3059\u3002<\/p>\n

\u80a5\u6e80\u306e\u4eba\u3067\u306f\u3001OGTT\u306e\u6700\u521d\u306e40\u5206\u9593\u3067\u3001\u6b63\u5e38\u4f53\u91cd\u3088\u308a\u3082\u9ad8\u3044\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u7dcf\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u3068\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u306e\u5897\u52a0\u5206\u306e\u66f2\u7dda\u4e0b\u9762\u7a4d\u306f\u3001\u4e21\u65b9\u306e\u4f53\u91cd\u7fa4\u3067\u9055\u3044\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30d6\u30c9\u30a6\u7cd6\u306e\u6442\u53d6\u306f\u3001\u4e21\u65b9\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u5185\u56e0\u6027\u30b0\u30eb\u30b3\u30fc\u30b9\u7523\u751f\u3092\u6025\u901f\u306b\u6291\u5236\u3057\u307e\u3057\u305f\u304c\u3001\u80a5\u6e80\u306e\u4eba\u306e\u65b9\u304c\u3088\u308a\u5185\u56e0\u6027\u30b0\u30eb\u30b3\u30fc\u30b9\u7523\u751f\u304c\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u30b9\u30af\u30e9\u30ed\u30fc\u30b9\u306e\u6442\u53d6\u304a\u3088\u3073\u5410\u304d\u51fa\u3057\u306f\u3001\u4e21\u65b9\u306e\u4f53\u91cd\u7fa4\u3067\u7dcf\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u307e\u305f\u306f\u7d4c\u53e3\u30b0\u30eb\u30b3\u30fc\u30b9\u51fa\u73fe\u7387\u306b\u5f71\u97ff\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4e21\u65b9\u306e\u4f53\u91cd\u7fa4\u306e\u3059\u3079\u3066\u306b\u304a\u3044\u3066\u30015\u6642\u9593\u306b\u308f\u305f\u3063\u3066\u5168\u8eab\u5faa\u74b0\u3059\u308b\u7d4c\u53e3\u6442\u53d6\u3055\u308c\u305f\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u91cf\u306f\u3001\u6442\u53d6\u3057\u305f\u30d6\u30c9\u30a6\u7cd675g\u306e70\uff05\u524d\u5f8c\u3067\u3057\u305f\u3002<\/p>\n

<\/div>\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u6b63\u5e38\u4f53\u91cd<\/th>\n\u80a5\u6e80<\/th>\n<\/tr>\n
\u6c34<\/th>\n\u30b9\u30af\u30e9\u30ed\u30fc\u30b9<\/th>\n\u5410\u304d\u51fa\u3057<\/th>\n\u6c34<\/th>\n\u30b9\u30af\u30e9\u30ed\u30fc\u30b9<\/th>\n\u5410\u304d\u51fa\u3057<\/th>\n<\/tr>\n<\/thead>\n
\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027<\/td>\n<\/tr>\n
S\u00a0I<\/sub>\u00a0[10\u00a0-5<\/sup>\u00a0dl\u30fbkg\u00a0-1<\/sup>\u30fbmin\u00a0-1<\/sup>\u00a0\/\uff08pmol \/ L\uff09]<\/td>\n16.3\u00b13.0<\/td>\n25.5\u00b16.1<\/td>\n19.7\u00b12.9<\/td>\n5.6\u00b10.8<\/td>\n4.8\u00b10.7<\/td>\n5.6\u00b10.5<\/td>\n<\/tr>\n
\u30a4\u30f3\u30b9\u30ea\u30f3\u30af\u30ea\u30a2\u30e9\u30f3\u30b9<\/td>\n<\/tr>\n
\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u7387\uff08L\u30fbmin\u00a0-1<\/sup>\uff09<\/td>\n1.7\u00b10.2<\/td>\n1.9\u00b10.2<\/td>\n1.9\u00b10.2<\/td>\n1.5\u00b10.1<\/td>\n1.5\u00b10.1<\/td>\n1.5\u00b10.1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u611f\u53d7\u6027\u3068\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u3067\u3059\u3002<\/p>\n

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 <\/p>\n

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\u7cd6\u8cea\u5236\u9650<\/span><\/p>\n

\u300cEffects of Sucralose Ingestion versus Sucralose Taste on Metabolic Responses to an Oral Glucose Tolerance Test in Participants with Normal Weight and Obesity: A Randomized Crossover Trial\u300d<\/span><\/p>\n

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