{"id":12828,"date":"2020-05-23T18:12:37","date_gmt":"2020-05-23T09:12:37","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=12828"},"modified":"2020-05-23T18:12:37","modified_gmt":"2020-05-23T09:12:37","slug":"post-12828","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=12828","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3068BCG\u30ef\u30af\u30c1\u30f3\u3000\u30d6\u30e9\u30b8\u30eb\u6025\u5897"},"content":{"rendered":"

\u6628\u65e5\u306e\u8a18\u4e8b\u306b\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u95a2\u9023\u306e\u8a18\u4e8b\u306f\u6b63\u76f4\u3082\u3046\u304a\u8179\u3044\u3063\u3071\u3044\u306b\u8fd1\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u308d\u305d\u308d\u30d5\u30a7\u30fc\u30c9\u30a2\u30a6\u30c8\u3057\u3066\u3082\u826f\u3044\u306e\u304b\u3068\u601d\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3084\u306f\u308a\u8208\u5473\u304c\u307e\u3060\u3042\u308b\u3082\u306e\u306b\u3064\u3044\u3066\u306f\u8a18\u4e8b\u306b\u3057\u3066\u304a\u304d\u305f\u3044\u306a\u3001\u3068\u3044\u3046\u6c17\u6301\u3061\u3082\u591a\u304f\u3042\u308a\u307e\u3059\u3002\u3067\u3059\u304b\u3089\u3001\u4eca\u65e5\u306f\u307e\u305f\u65b0\u578b\u30b3\u30ed\u30ca\u3001\u305d\u3057\u3066BCG\u3067\u3059\u3002<\/p>\n

\u30d6\u30e9\u30b8\u30eb\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u304c\u3053\u3053\u306b\u304d\u3066\u6025\u5897\u3057\u3066\u3044\u307e\u3059\u3002\u30a2\u30e1\u30ea\u30ab\u304c3\u6708\u4e2d\u65ec\u9803\u304b\u3089\u611f\u67d3\u304c\u6025\u5897\u3057\u59cb\u3081\u30ed\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u305f\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u3053\u308d\u306e\u30d6\u30e9\u30b8\u30eb\u306e\u611f\u67d3\u306f\u304a\u3068\u306a\u3057\u304b\u3063\u305f\u306e\u3067\u3059\u30024\u6708\u4e2d\u65ec\u3054\u308d\u307e\u3067\u30b8\u30ef\u30b8\u30ef\u3068\u3057\u304b\u5897\u52a0\u3057\u3066\u3044\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u3053\u3053\u306b\u304d\u3066\u611f\u67d3\u8005\uff08\u967d\u6027\u8005\uff09\u3084\u6b7b\u8005\u6570\u306f\u3069\u3093\u3069\u3093\u5897\u52a0\u3057\u3001\u611f\u67d3\u8005\u306f2\u4e07\u4eba\u3092\u3001\u6b7b\u8005\u306f1,000\u4eba\u3092\u8d85\u3048\u308b\u65e5\u3082\u3042\u308a\u307e\u3059\u3002\uff08\u4e0b\u306e\u56f3\u53c2\u7167\u3002\u56f3\u306f\u3053\u3053<\/a>\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

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\u5b8c\u5168\u306b\u30ce\u30fc\u30ac\u30fc\u30c9\u306e\u6226\u6cd5\u306e\u30d6\u30e9\u30b8\u30eb\u306fBCG\u63a5\u7a2e\u56fd\u3067\u3082\u3042\u308b\u306e\u3067\u3001BCG\u30ef\u30af\u30c1\u30f3\u304c\u65b0\u578b\u30b3\u30ed\u30ca\u306b\u6709\u76ca\u3067\u3042\u308b\u4eee\u8aac\u304c\u8aa4\u308a\u306a\u306e\u3067\u306f\u306a\u3044\u304b\uff1f\u3068\u56c1\u304b\u308c\u59cb\u3081\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002\u3055\u3089\u306bBCG\u306e\u682a\u3067\u65e5\u672c\u682a\u3084\u30ed\u30b7\u30a2\u682a\u304c\u975e\u5e38\u306b\u65b0\u578b\u30b3\u30ed\u30ca\u306e\u91cd\u75c7\u5316\u3092\u9632\u5fa1\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u4eee\u8aac\u306b\u3064\u3044\u3066\u3082\u3001\u3053\u306e\u30d6\u30e9\u30b8\u30eb\u306e\u611f\u67d3\u8005\u6025\u5897\u3067\u602a\u3057\u304f\u306a\u3063\u3066\u304d\u305f\u3001\u3068\u601d\u3046\u4eba\u3082\u51fa\u3066\u304d\u305f\u3088\u3046\u3067\u3059\u3002\u30d6\u30e9\u30b8\u30eb\u306eBCG\u682a\u306f\u30e2\u30ed\u30fc\u682a\u3068\u8a00\u3063\u3066\u3001\u30aa\u30ea\u30b8\u30ca\u30eb\u306eBCG\u306b\u8fd1\u3044\u65e5\u672c\u682a\u3084\u30ed\u30b7\u30a2\u682a\u3068\u540c\u3058\u4ef2\u9593\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n

\u30d6\u30e9\u30b8\u30eb\u306f\u300cThe BCG World Atlas<\/a>\u300d\u306b\u3088\u308b\u3068BCG\u306e\u56fd\u3068\u3057\u3066\u306e\u4e88\u9632\u63a5\u7a2e\u304c\u59cb\u307e\u3063\u305f\u306e\u304c1976\u5e74\u3068\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u524d\u306f\u30011927\u5e74\u306b\u7d4c\u53e3\u30ef\u30af\u30c1\u30f3\u3092\u958b\u59cb\u3057\u30011968\u5e74\u306b\u7d4c\u53e3\u30ef\u30af\u30c1\u30f3\u3092\u76ae\u5185\u30ef\u30af\u30c1\u30f3\u306b\u5909\u66f4\u3057\u305f\u3088\u3046\u3067\u3059\u3002\u4e00\u65b9Wikipedia<\/a>\u306b\u3088\u308b\u3068\u30011967\uff5e1968\u5e74\u306b\u30e6\u30cb\u30d0\u30fc\u30b5\u30ebBCG\u4e88\u9632\u63a5\u7a2e\u3092\u5c0e\u5165\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u30021967\u5e74\u306a\u3089\u73fe\u5728\u306e53\u6b73\u30011976\u5e74\u306a\u3089\u73fe\u572844\u6b73\u306e\u4eba\u3068\u306a\u308a\u307e\u3059\u3002\u305d\u308c\u4ee5\u524d\u306b\u751f\u307e\u308c\u305f\u4eba\u306b\u65e5\u672c\u306e\u3088\u3046\u306b\u30c4\u30d9\u30eb\u30af\u30ea\u30f3\u53cd\u5fdc\u3092\u898b\u3066\u3001\u4e88\u9632\u63a5\u7a2e\u3057\u3066\u3044\u305f\u304b\u3069\u3046\u304b\u306f\u4e0d\u660e\u3067\u3059\u3002<\/p>\n

\u4e88\u9632\u63a5\u7a2e\u304c\u59cb\u307e\u3063\u305f\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u30d6\u30e9\u30b8\u30eb\u306e\u4e73\u5150\u306eBCG\u63a5\u7a2e\u7387\u306f1980\u5e74\u3067\u308256\uff05\u3067\u3057\u305f\u30021990\u5e74\u3067\u308279\uff05\u3067\u3057\u305f\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u305d\u3053\u304b\u3089\u63a8\u6e2c\u3059\u308b\u3068\u3001\u6050\u3089\u304f\u4ee5\u524d\u306b\u751f\u307e\u308c\u305f\u4eba\u307e\u3067BCG\u306f\u3057\u3066\u3044\u306a\u304b\u3063\u305f\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u308f\u308c\u307e\u3059\u3002\u3082\u3057\u305d\u3046\u3060\u3068\u3059\u308b\u3068\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3057\u3066\u5f31\u3044\u3001\u9ad8\u9f62\u8005\u304c\u5168\u3066\u3001BCG\u672a\u63a5\u7a2e\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u3055\u3089\u306b\u3001BCG\u306e\u65e5\u672c\u682a\u3068\u30e2\u30ed\u30fc\u682a\u306f\u672c\u5f53\u306b\u4f3c\u3066\u3044\u308b\u306e\u304b\uff1f\u3068\u3044\u3046\u7591\u554f\u3067\u3059\u3002<\/p>\n

BCG\u306e\u65e5\u672c\u682a\u3068\u30e2\u30ed\u30fc\u682a\u3068\u30c7\u30f3\u30de\u30fc\u30af\u682a\u3092\u6bd4\u8f03\u3057\u305f\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

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\u305d\u3046\u3059\u308b\u3068\u3001\u65e5\u672c\u682a\u3067\u306fIL-1\u03b1\u3001IL-1\u03b2\u3001IL-6\u3001IL-24\u304c\u4ed6\u306e2\u3064\u306e\u682a\u3088\u308a\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002
\n\u4e00\u65b9\u30e2\u30ed\u30fc\u682a\u3068\u30c7\u30f3\u30de\u30fc\u30af\u682a\u3067\u306fIL-12\u03b2\u3001IL-27\u3001IFN-\u03b3\u304c\u65e5\u672c\u682a\u3088\u308a\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

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BCG\u306e\u30e2\u30ed\u30fc\u682a\u306e\u30d6\u30e9\u30b8\u30eb\u306f\u3001\u3061\u3087\u3063\u3068\u65e5\u672c\u682a\u3088\u308a\u81ea\u7136\u514d\u75ab\u306e\u30d6\u30fc\u30b9\u30c8\u304c\u5f31\u3044\u306e\u3067\u3057\u3087\u3046\u3002\u30aa\u30ea\u30b8\u30ca\u30eb\u306eBCG\u306b\u8fd1\u3044\u306f\u305a\u3067\u3059\u304c\u3001\u751f\u4f53\u306e\u53cd\u5fdc\u306f\u30c7\u30f3\u30de\u30fc\u30af\u682a\u306b\u8fd1\u3044\u3082\u306e\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30d6\u30e9\u30b8\u30eb\u304c\u611f\u67d3\u7206\u767a\u3059\u308b\u306e\u306f\u3001BCG\u63a5\u7a2e\u5e74\u9f62\u3068\u3001\u30e2\u30ed\u30fc\u682a\u3067\u5341\u5206\u306b\u8aac\u660e\u3067\u304d\u307e\u3059\u3002\u3055\u3059\u304c\u306b\u30ce\u30fc\u30ac\u30fc\u30c9\u3067\u306f\u30d6\u30e9\u30b8\u30eb\u3082\u82e6\u3057\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u3060\u307e\u3060BCG\u4eee\u8aac\u7d9a\u304d\u305d\u3046\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u300cUnique Gene Expression Profiles in Infants Vaccinated With Different Strains of Mycobacterium Bovis Bacille Calmette-Guerin\u300d<\/span><\/p>\n

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