{"id":1326,"date":"2017-05-03T20:17:00","date_gmt":"2017-05-03T11:17:00","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=1326"},"modified":"2017-05-03T20:17:00","modified_gmt":"2017-05-03T11:17:00","slug":"post-1326","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=1326","title":{"rendered":"O\u578b\u306e\u8840\u6db2\u578b\u306f\u3061\u3087\u3063\u3068\u3060\u3051\u5fc3\u81d3\u304c\u5f37\u3044\uff1f"},"content":{"rendered":"<p>O\u578b\u306e\u8840\u6db2\u578b\u3060\u3068\u3001\u5fc3\u81d3\u767a\u4f5c\u304c\u3061\u3087\u3063\u3068\u3060\u3051\u8d77\u304d\u306b\u304f\u3044\u3068\u3044\u3046\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002\u5360\u3044\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001O\u578b\u306e\u79c1\u306f\u3061\u3087\u3063\u3068\u3060\u3051\u5f97\u3057\u305f\u6c17\u5206\u3067\u3059\u3002<\/p>\n<p>Heart Failure 2017 and the 4th World Congress on Acute Heart Failure.1\u3067\u767a\u8868\u3055\u308c\u305f\u3053\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u975eO\u578b\u306e\u8840\u6db2\u578b\uff08A\u3001B\u3001AB\uff09\u306e\u4eba\u305f\u3061\u306f\u5fc3\u81d3\u767a\u4f5c\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305d\u3046\u3067\u3059\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u30ec\u30d9\u30eb\u306e\u4f4e\u3044\u7814\u7a76\u3060\u3068\u8a8d\u3081\u3066\u306f\u3044\u307e\u3059\u304c\u3001\u9762\u767d\u3044\u3053\u3068\u3092\u7814\u7a76\u3059\u308b\u4eba\u3082\u3044\u308b\u306e\u3060\u306a\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p><span title=\"The study included 1 362 569 subjects from 11 prospective cohorts, described in nine articles.\">\u3053\u306e\u7814\u7a76\u306b\u306f\u300111\u306e\u524d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u304b\u3089\u306e1,362,569\u4eba\u306e\u88ab\u9a13\u8005\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/span><span title=\"There were a total of 23 154 cardiovascular events.\">\u5168\u90e8\u306723,154\u306e\u5fc3\u81d3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/span><span title=\"The researchers analysed the association between blood group and all coronary events, combined cardiovascular events, and fatal coronary events.\n\n\">\u7814\u7a76\u8005\u306f\u3001\u8840\u6db2\u578b\u3068\u3059\u3079\u3066\u306e\u51a0\u72b6\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u3001\u5fc3\u8840\u7ba1\u7cfb\u30a4\u30d9\u30f3\u30c8\u3068\u81f4\u6b7b\u7684\u51a0\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u3068\u306e\u95a2\u9023\u6027\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002<span title=\"The odds ratio (OR) for all coronary events was significantly higher in carriers of a non-O blood group, at 1.09 (95% confidence interval [CI] of 1.06-1.13).\n\n\">\u3059\u3079\u3066\u306e\u51a0\u72b6\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u306e\u30aa\u30c3\u30ba\u6bd4\uff08OR\uff09\u306f\u30011.09\uff0895\uff05\u4fe1\u983c\u533a\u9593[CI] = 1.06-1.13\uff09\u3067\u3001\u975eO\u578b\u306e\u8840\u6db2\u7fa4\u306b\u304a\u3044\u3066\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306eOR\u306f\u3001\u975eO\u578b\u8840\u6db2\u7fa4\u3067\u306f1.09\uff0895\uff05CI 1.06-1.11\uff09\u3067\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002\u3057\u304b\u3057\u3001<span title=\"The analysis of fatal coronary events did not show a significant difference between people with O and non-O blood groups.\n\n\">\u81f4\u6b7b\u7684\u306a\u51a0\u72b6\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u306e\u5206\u6790\u306f\u3001O\u578b\u304a\u3088\u3073\u975eO\u578b\u8840\u6db2\u7fa4\u306e\u4eba\u3005\u306e\u9593\u306b\u6709\u610f\u5dee\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<\/span><\/span><\/span><\/p>\n<p>\u3064\u307e\u308a\u3001\u975eO\u578b\u306e\u8840\u6db2\u578b\u3092\u6709\u3059\u308b\u3053\u3068\u306f\u3001\u51a0\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u304c9\uff05\u5897\u52a0\u3057\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3001\u7279\u306b\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u304c9\uff05\u5897\u52a0\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u306e\u30ea\u30b9\u30af\u306e\u5897\u52a0\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u307e\u3060\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u304c\u3001<span title=\"The higher risk for cardiovascular events in non-O blood group carriers may be due to having greater concentrations of von Willebrand factor, a blood clotting protein which has been associated with thrombotic events.\">\u975eO\u578b\u306e\u8840\u6db2\u578b\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u306f\u3001\u8840\u6813\u6027\u30a4\u30d9\u30f3\u30c8\u306b\u95a2\u9023\u3059\u308b\u8840\u6db2\u51dd\u56fa\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308b\u30d5\u30a9\u30f3\u30d3\u30eb\u30d6\u30e9\u30f3\u30c8\u56e0\u5b50\u306e\u6fc3\u5ea6\u304c\u9ad8\u3044\u3053\u3068\u306b\u8d77\u56e0\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/span><span title=\"Further, non-O blood group carriers, specifically those with an A blood group, are known to have higher cholesterol.\">\u3055\u3089\u306b\u3001\u975eO\u578b\u306e\u8840\u6db2\u578b\u3001\u7279\u306bA\u578b\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u3088\u308a\u9ad8\u3044\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002<\/span><span title=\"And galectin-3, which is linked to inflammation and worse outcomes in heart failure patients, is also higher in those with a non-O blood group.\n\n\">\u307e\u305f\u3001\u30ac\u30ec\u30af\u30c1\u30f3-3\u306f\u3001\u5fc3\u4e0d\u5168\u60a3\u8005\u306e\u708e\u75c7\u304a\u3088\u3073\u60aa\u5316\u3057\u305f\u7d50\u679c\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u975eO\u8840\u6db2\u7fa4\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u3082\u9ad8\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/span><\/p>\n<p>\u3044\u305c\u308c\u306b\u3057\u3066\u3082\u3001\u4f55\u304b\u8840\u6db2\u578b\u3067\u9055\u3044\u306f\u3042\u308a\u305d\u3046\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u7814\u7a76\u306e\u8a18\u4e8b\u306e\u539f\u6587\u306f<a href=\"https:\/\/www.eurekalert.org\/pub_releases\/2017-04\/esoc-nbg042817.php\" target=\"_blank\" rel=\"noopener noreferrer\">\u3053\u3053<\/a>\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>O\u578b\u306e\u8840\u6db2\u578b\u3060\u3068\u3001\u5fc3\u81d3\u767a\u4f5c\u304c\u3061\u3087\u3063\u3068\u3060\u3051\u8d77\u304d\u306b\u304f\u3044\u3068\u3044\u3046\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002\u5360\u3044\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001O\u578b\u306e\u79c1\u306f\u3061\u3087\u3063\u3068\u3060\u3051\u5f97\u3057\u305f\u6c17\u5206\u3067\u3059\u3002 Heart Failure 2017 and the 4th World Congre<\/p>\n","protected":false},"author":1,"featured_media":1327,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[15,13],"tags":[],"class_list":["post-1326","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-15","category-13","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/05\/08f795828ddec05655106a124905b972_s.jpg?fit=640%2C428&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-lo","jetpack-related-posts":[{"id":8246,"url":"https:\/\/promea2014.com\/blog\/?p=8246","url_meta":{"origin":1326,"position":0},"title":"\u8840\u6db2\u578b\u5360\u3044\u3067\u306f\u306a\u3044\uff01\u3000O\u578b\u306f\u51fa\u8840\u6b7b\u30ea\u30b9\u30af\u304c\u9ad8\u3044\uff1f","author":"Dr.Shimizu","date":"2019\u5e746\u670815\u65e5","format":false,"excerpt":"\u8840\u6db2\u578b\u5360\u3044\u304c\u597d\u304d\u306a\u65b9\u3082\u3044\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u79c1\u306e\u8840\u6db2\u578b\u306fO\u578b\u3067\u3059\u3002\u4ee5\u524d\u306e\u8a18\u4e8b\u300cO\u578b\u306e\u8840\u6db2\u578b\u306f\u3061\u3087\u3063\u3068\u3060\u2026","rel":"","context":"\u672a\u5206\u985e","block_context":{"text":"\u672a\u5206\u985e","link":"https:\/\/promea2014.com\/blog\/?cat=1"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/0b0512a16688265e7c3cc8fe528da458_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/0b0512a16688265e7c3cc8fe528da458_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 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