{"id":14208,"date":"2020-10-09T08:44:59","date_gmt":"2020-10-08T23:44:59","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=14208"},"modified":"2020-10-09T08:44:59","modified_gmt":"2020-10-08T23:44:59","slug":"post-14208","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=14208","title":{"rendered":"\u300c\u8001\u5316\u300d\u3068\u3044\u3046\u4fbf\u5229\u306a\u8a00\u8449"},"content":{"rendered":"<p>\u5916\u6765\u306e\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u308b\u3068\u304d\u306b\u3001\u79c1\u306e\u60a3\u8005\u3055\u3093\u306f\u307b\u3068\u3093\u3069\u304c\u3069\u3053\u304b\u306e\u75c5\u9662\u3001\u3069\u3053\u304b\u306e\u79d1\u3092\u3059\u3067\u306b\u53d7\u8a3a\u3057\u305f\u72b6\u614b\u3067\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3059\u3002\u305d\u306e\u60a3\u8005\u3055\u3093\u306b\u8a71\u3092\u805e\u304f\u3068\u3001\u305d\u306e\u75c7\u72b6\u306e\u539f\u56e0\u306b\u3064\u3044\u3066\u300c\u8001\u5316\u300d\u3060\u3068\u8aac\u660e\u3055\u308c\u305f\u3001\u3068\u3044\u3046\u3053\u3068\u304c\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u300c\u8001\u5316\u300d\u3068\u3044\u3046\u8a00\u8449\u306f\u533b\u5e2b\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u4fbf\u5229\u3067\u3059\u3002\u308f\u304b\u3089\u306a\u3044\u75c7\u72b6\u3001\u6cbb\u7642\u304c\u4e0a\u624b\u304f\u3044\u304b\u306a\u3044\u75c7\u72b6\u3092\u300c\u8001\u5316\u300d\u3068\u8aac\u660e\u3059\u308c\u3070\u826f\u3044\u306e\u3067\u3059\u304b\u3089\u3002\u300c\u8001\u5316\u300d\u306b\u6295\u4e0e\u3059\u308b\u85ac\u306f\u3042\u308a\u307e\u305b\u3093\u304b\u3089\u3002<\/p>\n<p>\u60a3\u8005\u5074\u3068\u3057\u3066\u306f\u3001\u300c\u8001\u5316\u300d\u3060\u304b\u3089\u6cbb\u3089\u306a\u304f\u3066\u3082\u4ed5\u65b9\u304c\u306a\u3044\u3001\u300c\u8001\u5316\u300d\u3060\u304b\u3089\u8ae6\u3081\u306a\u3055\u3044\u3001\u300c\u8001\u5316\u300d\u3060\u304b\u3089\u7279\u306b\u6cbb\u7642\u6cd5\u306f\u306a\u3044\u3001\u306a\u3069\u6297\u3048\u306a\u3044\u904b\u547d\u306e\u3088\u3046\u306b\u611f\u3058\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n<p>\u3082\u3061\u308d\u3093\u3001\u4eba\u9593\u306f\u3044\u3064\u304b\u6b7b\u306c\u306e\u3067\u3001\u4f55\u3089\u304b\u306e\u52a0\u9f62\u6027\u5909\u5316\u306f\u8d77\u3053\u308a\u307e\u3059\u300290\u6b73\u306e\u4eba\u306b\u300c\u8001\u5316\u300d\u3068\u3044\u3046\u8a00\u8449\u3092\u4f7f\u3046\u3053\u3068\u306f\u554f\u984c\u3042\u308a\u307e\u305b\u3093\u304c\u300150\u4ee3\u308460\u4ee3\u3067\u300c\u8001\u5316\u300d\u3068\u3044\u3046\u8a00\u8449\u3092\u4f7f\u3046\u3053\u3068\u306f\u79c1\u306f\u9055\u548c\u611f\u3092\u611f\u3058\u307e\u3059\u3002<\/p>\n<p>\u52a0\u9f62\u3084\u75be\u60a3\u306b\u3088\u308a\u7b4b\u8089\u91cf\u304c\u6e1b\u5c11\u3057\u3066\u3001\u5168\u8eab\u306e\u7b4b\u529b\u4f4e\u4e0b\u304a\u3088\u3073\u8eab\u4f53\u6a5f\u80fd\u306e\u4f4e\u4e0b\u304c\u8d77\u3053\u308b\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u306f\u6700\u7d42\u7684\u306b\u306f\u907f\u3051\u3089\u308c\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u305d\u3053\u306b\u81f3\u308b\u30b9\u30d4\u30fc\u30c9\u306f\u9045\u304f\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3060\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u300170\u301c79\u6b73\u306e1,840\u4eba\u306e\u9ad8\u9f62\u8005\u3092\u5bfe\u8c61\u306b\u30012\u578b\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u3067\u30013\u5e74\u5f8c\u7b4b\u529b\u304c\u3069\u3046\u306a\u3063\u3066\u3044\u308b\u304b\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<div class=\"table-caption\">\n<div class=\"sb-div caption-clear\"><\/div>\n<\/div>\n<table id=\"table-2\" class=\"table-expansion-content\">\n<thead id=\"thead-2\">\n<tr id=\"tr-35\">\n<th id=\"th-5\" align=\"center\" valign=\"bottom\"><\/th>\n<th id=\"th-6\" align=\"center\" valign=\"bottom\">\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3<\/th>\n<th id=\"th-7\" align=\"center\" valign=\"bottom\">\u7cd6\u5c3f\u75c5\u306a\u305736\u30f6\u6708\u5f8c<\/th>\n<th id=\"th-8\" align=\"center\" valign=\"bottom\">\u5909\u5316<\/th>\n<th id=\"th-9\" align=\"center\" valign=\"bottom\">\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3<\/th>\n<th id=\"th-10\" align=\"center\" valign=\"bottom\">\u7cd6\u5c3f\u75c5\u3042\u308a36\u30f6\u6708\u5f8c<\/th>\n<th id=\"th-11\" align=\"center\" valign=\"bottom\">\u5909\u5316<\/th>\n<th id=\"th-12\" align=\"center\" valign=\"bottom\"><em>P<\/em>\u5024<\/th>\n<\/tr>\n<\/thead>\n<tbody id=\"tbody-2\">\n<tr id=\"tr-37\">\n<td id=\"td-141\" align=\"left\" valign=\"top\">\u819d\u4f38\u7b4b<\/td>\n<td id=\"td-142\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-143\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-144\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-145\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-146\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-147\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-148\" align=\"center\" valign=\"top\"><\/td>\n<\/tr>\n<tr id=\"tr-38\">\n<td id=\"td-149\" align=\"left\" valign=\"top\">\u6700\u5927\u30c8\u30eb\u30af\uff08Nm\uff09<\/td>\n<td id=\"td-150\" align=\"center\" valign=\"top\">109.1\u00b10.7<\/td>\n<td id=\"td-151\" align=\"center\" valign=\"top\">96.8\u00b10.7<\/td>\n<td id=\"td-152\" align=\"center\" valign=\"top\">-12.4\u00b10.5<\/td>\n<td id=\"td-153\" align=\"center\" valign=\"top\">111.3\u00b11.5<\/td>\n<td id=\"td-154\" align=\"center\" valign=\"top\">94.8\u00b11.5<\/td>\n<td id=\"td-155\" align=\"center\" valign=\"top\">-16.5\u00b11.2<\/td>\n<td id=\"td-156\" align=\"char\" char=\".\" valign=\"top\">0.001<\/td>\n<\/tr>\n<tr id=\"tr-39\">\n<td id=\"td-157\" align=\"left\" valign=\"top\">\u811a\u306e\u9664\u8102\u80aa\u91cf\uff08kg\uff09<\/td>\n<td id=\"td-158\" align=\"center\" valign=\"top\">7.52\u00b10.03<\/td>\n<td id=\"td-159\" align=\"center\" valign=\"top\">7.29\u00b10.03<\/td>\n<td id=\"td-160\" align=\"center\" valign=\"top\">\u22120.23\u00b10.01<\/td>\n<td id=\"td-161\" align=\"center\" valign=\"top\">7.96\u00b10.07<\/td>\n<td id=\"td-162\" align=\"center\" valign=\"top\">7.66\u00b10.07<\/td>\n<td id=\"td-163\" align=\"center\" valign=\"top\">\u22120.29\u00b10.03<\/td>\n<td id=\"td-164\" align=\"char\" char=\".\" valign=\"top\">0.035<\/td>\n<\/tr>\n<tr id=\"tr-40\">\n<td id=\"td-165\" align=\"left\" valign=\"top\">\u5358\u4f4d\u7b4b\u8089\u91cf\u3042\u305f\u308a\u306e\u7b4b\u529b\uff08Nm \/ kg\uff09<\/td>\n<td id=\"td-166\" align=\"center\" valign=\"top\">14.4\u00b10.1<\/td>\n<td id=\"td-167\" align=\"center\" valign=\"top\">13.2\u00b10.1<\/td>\n<td id=\"td-168\" align=\"center\" valign=\"top\">\u22121.2\u00b10.1<\/td>\n<td id=\"td-169\" align=\"center\" valign=\"top\">14.0\u00b10.2<\/td>\n<td id=\"td-170\" align=\"center\" valign=\"top\">12.4\u00b10.2<\/td>\n<td id=\"td-171\" align=\"center\" valign=\"top\">\u22121.6\u00b10.2<\/td>\n<td id=\"td-172\" align=\"char\" char=\".\" valign=\"top\">0.034<\/td>\n<\/tr>\n<tr id=\"tr-41\">\n<td id=\"td-173\" align=\"left\" valign=\"top\">\u63e1\u529b<\/td>\n<td id=\"td-174\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-175\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-176\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-177\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-178\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-179\" align=\"center\" valign=\"top\"><\/td>\n<td id=\"td-180\" align=\"center\" valign=\"top\"><\/td>\n<\/tr>\n<tr id=\"tr-42\">\n<td id=\"td-181\" align=\"left\" valign=\"top\">\u6700\u5927\u7b4b\u529b\uff08kg\uff09<\/td>\n<td id=\"td-182\" align=\"center\" valign=\"top\">32.6\u00b10.2<\/td>\n<td id=\"td-183\" align=\"center\" valign=\"top\">31.3\u00b10.2<\/td>\n<td id=\"td-184\" align=\"center\" valign=\"top\">\u22121.3\u00b10.1<\/td>\n<td id=\"td-185\" align=\"center\" valign=\"top\">32.1\u00b10.4<\/td>\n<td id=\"td-186\" align=\"center\" valign=\"top\">30.8\u00b10.4<\/td>\n<td id=\"td-187\" align=\"center\" valign=\"top\">\u22121.3\u00b10.3<\/td>\n<td id=\"td-188\" align=\"char\" char=\".\" valign=\"top\">0.964<\/td>\n<\/tr>\n<tr id=\"tr-43\">\n<td id=\"td-189\" align=\"left\" valign=\"top\">\u8155\u306e\u9664\u8102\u80aa\u91cf\uff08kg\uff09<\/td>\n<td id=\"td-190\" align=\"center\" valign=\"top\">2.75\u00b10.01<\/td>\n<td id=\"td-191\" align=\"center\" valign=\"top\">2.70\u00b10.01<\/td>\n<td id=\"td-192\" align=\"center\" valign=\"top\">\u22120.06\u00b10.01<\/td>\n<td id=\"td-193\" align=\"center\" valign=\"top\">2.92\u00b10.03<\/td>\n<td id=\"td-194\" align=\"center\" valign=\"top\">2.83\u00b10.03<\/td>\n<td id=\"td-195\" align=\"center\" valign=\"top\">\u22120.08\u00b10.01<\/td>\n<td id=\"td-196\" align=\"char\" char=\".\" valign=\"top\">0.025<\/td>\n<\/tr>\n<tr id=\"tr-44\">\n<td id=\"td-197\" align=\"left\" valign=\"top\">\u5358\u4f4d\u7b4b\u8089\u91cf\u3042\u305f\u308a\u306e\u7b4b\u529b\uff08kg \/ kg\uff09<\/td>\n<td id=\"td-198\" align=\"center\" valign=\"top\">12.0\u00b10.1<\/td>\n<td id=\"td-199\" align=\"center\" valign=\"top\">11.8\u00b10.1<\/td>\n<td id=\"td-200\" align=\"center\" valign=\"top\">\u22120.2\u00b10.1<\/td>\n<td id=\"td-201\" align=\"center\" valign=\"top\">11.2\u00b10.1<\/td>\n<td id=\"td-202\" align=\"center\" valign=\"top\">11.0\u00b10.1<\/td>\n<td id=\"td-203\" align=\"center\" valign=\"top\">\u22120.2\u00b10.1<\/td>\n<td id=\"td-204\" align=\"char\" char=\".\" valign=\"top\">0.757<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4e0a\u306e\u8868\u306f\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u4eba\u3068\u306a\u3044\u4eba\u306e36\u304b\u6708\u5f8c\u306e\u7b4b\u529b\u3084\u7b4b\u8089\u91cf\u306e\u5909\u5316\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u819d\u306e\u4f38\u7b4b\u3068\u8155\u306e\u7b4b\u8089\u91cf\u306f\u3069\u3061\u3089\u3082\u7cd6\u5c3f\u75c5\u6709\u308a\u306e\u4eba\u306e\u65b9\u304c\u4f4e\u4e0b\u304c\u5927\u304d\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u63e1\u529b\u306e\u9055\u3044\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u4e0b\u80a2\u306e\u819d\u306e\u7b4b\u529b\u306f\u7cd6\u5c3f\u75c5\u306e\u3042\u308b\u4eba\u306e\u65b9\u304c\u5927\u304d\u304f\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u7b4b\u8089\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306e\u6700\u3082\u5927\u304d\u306a\u539f\u56e0\u306f\u6050\u3089\u304fAGEs\uff08\u7d42\u672b\u7cd6\u5316\u7523\u7269\uff09\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u4ed6\u306e\u7814\u7a76\u3067\u306f\u3001AGEs\u306b\u3088\u308b\u7b4b\u529b\u306e\u9055\u3044\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u4eba\u306e\u5065\u5eb7\u306a\u6bd4\u8f03\u7684\u82e5\u3044\u7537\u6027\uff08\u5e73\u574746\u6b73\uff09\u306e\u76ae\u819a\u306eAGEs\u84c4\u7a4d\u91cf\u3068\u63e1\u529b\u3084\u811a\u4f38\u5c55\u529b\u306e\u6bd4\u8f03\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u306f\u3001\u60f3\u50cf\u901a\u308a\u3001AGEs\u304c\u591a\u3044\u307b\u3069\u7b4b\u529b\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>AGEs\u306f\u69d8\u3005\u306a\u8001\u5316\u3001\u6a5f\u80fd\u969c\u5bb3\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u7cd6\u5316\u3092\u8d77\u3053\u3055\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u305f\u3081\u306b\u306f\u8840\u7cd6\u5024\u3092\u4e0a\u3052\u306a\u3044\u3053\u3068\u3067\u3059\u3002\u7cd6\u8cea\u5236\u9650\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u7cd6\u5316\u306f\u6700\u5c0f\u9650\u306b\u6291\u3048\u3089\u308c\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u4f55\u3089\u304b\u306e\u75c7\u72b6\u3067\u300c\u8001\u5316\u300d\u3068\u3044\u3046\u8a00\u8449\u3092\u805e\u3044\u305f\u3089\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002\u672c\u5f53\u306b\u300c\u8001\u5316\u300d\u306a\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u300c\u7cd6\u5316\u300d\u306a\u306e\u304b\u3002<\/p>\n<p><span style=\"color: #ffffff;\">\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300cAccelerated loss of skeletal muscle strength in older adults with type 2 diabetes: the health, aging, and body composition study\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c2\u578b\u7cd6\u5c3f\u75c5\u306e\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u9aa8\u683c\u7b4b\u5f37\u5ea6\u306e\u52a0\u901f\u3055\u308c\u305f\u55aa\u5931\uff1a\u5065\u5eb7\u3001\u8001\u5316\u3001\u304a\u3088\u3073\u4f53\u7d44\u6210\u306e\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17363749\/\" target=\"_blank\" rel=\"noopener 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