{"id":16592,"date":"2021-08-12T07:33:25","date_gmt":"2021-08-11T22:33:25","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=16592"},"modified":"2021-08-12T07:34:28","modified_gmt":"2021-08-11T22:34:28","slug":"post-16592","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=16592","title":{"rendered":"\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u75c5\u5b66\u4f1a\u306f\u4e2d\u6027\u8102\u80aa\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u4ecb\u5165\u3068\u3057\u3066\u7cd6\u8cea\u5236\u9650\u3092\u63d0\u5531\u3000\u305d\u306e2"},"content":{"rendered":"<p>\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u75c5\u5b66\u4f1a\u306f\u4e2d\u6027\u8102\u80aa\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u98df\u4e8b\u3068\u3057\u3066\u7cd6\u8cea\u5236\u9650\u3092\u63d0\u5531\u3057\u307e\u3057\u305f\u3002\u524d\u56de\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=16574\" target=\"_blank\" rel=\"noopener\">\u305d\u306e1<\/a>\u300d\u306e\u7d9a\u304d\u3067\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">High-protein diets: A higher-protein diet is defined as having 25% of energy from protein, 30% from fat, and 45% from carbohydrates. A higher-protein (31% of energy) versus a standard-protein (18% of energy) weight-loss diet causes greater weight loss (\u22120.79 kg; 95% CI: \u22121.50 to 0.08 kg) and triglyceride lowering (\u221220 mg\/dL; 95% CI: \u221229 to 11 mg\/dL). In a study of individuals with metabolic syndrome (n = 110; baseline triglycerides = 179 mg\/dL), after 12 months on a high-protein (1.34 g\/kg body weight) weight-loss diet (500-calorie deficit per day) versus a conventional weight-loss diet (0.8 g\/kg body weight of protein), those on the high-protein diet had greater weight loss (9 kg) than the conventional diet (6.4 kg). In addition, those on the high-protein diet had a 35% reduction in triglycerides versus a nonsignificant 5% reduction in the conventional diet group.<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\uff1a\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u306e25\uff05\u304c\u30bf\u30f3\u30d1\u30af\u8cea\u300130\uff05\u304c\u8102\u80aa\u300145\uff05\u304c\u70ad\u6c34\u5316\u7269\u3067\u3042\u308b\u3068\u5b9a\u7fa9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6a19\u6e96\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30a8\u30cd\u30eb\u30ae\u30fc\u306e18\uff05\uff09\u3068\u6bd4\u8f03\u3057\u3066\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30a8\u30cd\u30eb\u30ae\u30fc\u306e31\uff05\uff09\u306e\u6e1b\u91cf\u98df\u306f\u3001\u3088\u308a\u5927\u304d\u306a\u6e1b\u91cf\uff08-0.79 kg; 95\uff05CI\uff1a-1.50\u301c0.08 kg\uff09\u3068\u4e2d\u6027\u8102\u80aa\u4f4e\u4e0b\uff08-20 mg \/ dL; 95\uff05CI\uff1a-29\u301c11 mg \/ dL\uff09\u3092\u793a\u3057\u307e\u3059\u3002\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\uff08n = 110;\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u4e2d\u6027\u8102\u80aa= 179 mg \/ dL\uff09\u306e\u4eba\u306e\u7814\u7a76\u3067\u306f\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\uff081.34 g \/ kg\u4f53\u91cd\uff09\u306e\u6e1b\u91cf\u98df\uff081\u65e5\u3042\u305f\u308a500\u30ab\u30ed\u30ea\u30fc\u306e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\uff09\u306712\u304b\u6708\u5f8c\u5f93\u6765\u306e\u6e1b\u91cf\u98df\uff080.8g \/ kg\u4f53\u91cd\u306e\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u306e\u4eba\u306f\u3001\u5f93\u6765\u306e\u98df\u4e8b\u3067\u306e6.4kg\u3088\u308a\u3082\u5927\u304d\u306a\u6e1b\u91cf\uff089kg\uff09\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u3092\u6442\u53d6\u3057\u3066\u3044\u308b\u4eba\u306f\u3001\u4e2d\u6027\u8102\u80aa\u304c35\uff05\u6e1b\u5c11\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001\u5f93\u6765\u306e\u98df\u4e8b\u7fa4\u3067\u306f5\uff05\u6e1b\u5c11\u3067\u3057\u305f\u3002<\/span><\/p>\n<p>\u3053\u3053\u3067\u306f\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u306e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\u304c\u4e2d\u6027\u8102\u80aa\u3084\u4f53\u91cd\u6e1b\u5c11\u306b\u6709\u76ca\u3067\u3042\u308b\u3053\u3068\u304c\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u3061\u3087\u3063\u3068\u7cd6\u8cea\u5236\u9650\u3068\u306f\u9055\u3046\u98df\u4e8b\u3067\u3059\u306d\u3002<\/p>\n<p><span style=\"color: #3366ff;\">Intermittent fasting: Common forms of intermittent fasting are alternate-day (3 to 4 days\/wk, consumption of \u226425% of energy needs during a 24-h period) and periodic fasting (fasting 1 or 2 days\/wk). One type of intermittent fasting\u2014time-restricted eating\u2014describes a scenario in which food intake is limited to a specific window of time each day. An AHA Scientific Statement summarized the effects of intermittent fasting regimens on body weight loss and changes in triglycerides, as summarized in 10 intervention studies. After 3 to 24 weeks of intervention, participants had a 3% to 8% weight loss on average. Weight loss was greater with alternate-day fasting (0.75 kg\/wk) versus periodic fasting (0.25 kg\/wk). Triglycerides decreased 16% to 42%, with the greatest decreases in triglycerides associated with the greatest weight loss. With a 1-kg per week weight loss, triglycerides decreased \u224830% to 40%, and with a 0.25- to 0.5-kg per week weight loss, triglycerides decreased by \u224810% to 20%. In 3 systematic reviews and meta-analyses conducted to evaluate the effects of time-restricted eating and\/or intermittent fasting (vs control) on weight loss and cardiometabolic risk factors, weight loss ranged from 1 to 4 kg and triglycerides decreased by 6 to 12 mg\/dL.<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u30a4\u30f3\u30bf\u30fc\u30df\u30c3\u30c6\u30f3\u30c8\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\uff08\u65ad\u7d9a\u7684\u65ad\u98df\uff09\uff1a\u65ad\u7d9a\u7684\u65ad\u98df\u306e\u4e00\u822c\u7684\u306a\u5f62\u614b\u306f\u3001\u9694\u65e5\uff083\u301c4\u65e5\/\u9031\u300124\u6642\u9593\u306e\u9593\u306b\u5fc5\u8981\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u306e25\uff05\u4ee5\u4e0b\u306e\u6d88\u8cbb\uff09\u3068\u5b9a\u671f\u7684\u65ad\u98df\uff081\u65e5\u307e\u305f\u306f2\u65e5\/\u9031\u306e\u65ad\u98df\uff09\u3067\u3059\u3002\u65ad\u7d9a\u7684\u65ad\u98df\u306e\u4e00\u7a2e\u3067\u3042\u308b\u6642\u9593\u5236\u9650\u306e\u3042\u308b\u98df\u4e8b\u306f\u3001\u98df\u7269\u6442\u53d6\u304c\u6bce\u65e5\u7279\u5b9a\u306e\u6642\u9593\u67a0\u306b\u5236\u9650\u3055\u308c\u308b\u30b7\u30ca\u30ea\u30aa\u3092\u3044\u3044\u307e\u3059\u3002AHA\u306e\u58f0\u660e\u306f\u300110\u306e\u4ecb\u5165\u7814\u7a76\u306b\u8981\u7d04\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001\u65ad\u7d9a\u7684\u65ad\u98df\u7642\u6cd5\u304c\u4f53\u91cd\u6e1b\u5c11\u3068\u4e2d\u6027\u8102\u80aa\u306e\u5909\u5316\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u8981\u7d04\u3057\u3066\u3044\u307e\u3059\u30023\u301c24\u9031\u9593\u306e\u4ecb\u5165\u5f8c\u3001\u53c2\u52a0\u8005\u306f\u5e73\u5747\u3057\u30663\u301c8\uff05\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u4f53\u91cd\u6e1b\u5c11\u306f\u3001\u65ad\u7d9a\u7684\u65ad\u98df\uff080.25kg \/\u9031\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001\u9694\u65e5\u65ad\u98df\uff080.75kg \/\u9031\uff09\u306e\u65b9\u304c\u5927\u304d\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u4e2d\u6027\u8102\u80aa\u306f16\uff05\u306842\uff05\u6e1b\u5c11\u3057\u3001\u4e2d\u6027\u8102\u80aa\u306e\u6700\u5927\u306e\u6e1b\u5c11\u306f\u6700\u5927\u306e\u4f53\u91cd\u6e1b\u5c11\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u9031\u306b1kg\u306e\u4f53\u91cd\u6e1b\u5c11\u3067\u3001\u4e2d\u6027\u8102\u80aa\u306f\u7d0430\uff05\u304b\u308940\uff05\u6e1b\u5c11\u3057\u3001\u9031\u306b0.25\u304b\u30890.5 kg\u306e\u4f53\u91cd\u6e1b\u5c11\u3067\u3001\u4e2d\u6027\u8102\u80aa\u306f\u7d0410\uff05\u304b\u308920\uff05\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002\u6642\u9593\u5236\u9650\u306e\u3042\u308b\u98df\u4e8b\u304a\u3088\u3073\/\u307e\u305f\u306f\u65ad\u7d9a\u7684\u65ad\u98df\uff08\u5bfe\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\uff09\u304c\u4f53\u91cd\u6e1b\u5c11\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u4ee3\u8b1d\u306e\u5371\u967a\u56e0\u5b50\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u5b9f\u65bd\u3055\u308c\u305f3\u3064\u306e\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u304a\u3088\u3073\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306f1\u301c4 kg\u306e\u7bc4\u56f2\u3067\u3042\u308a\u3001\u4e2d\u6027\u8102\u80aa\u306f6\u301c12mg\/dL\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002<\/span><\/p>\n<p>\u6b21\u306b\u793a\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u65ad\u98df\u7cfb\u3067\u3059\u3002\u69d8\u3005\u306a\u65b9\u6cd5\u306f\u3042\u308b\u3067\u3057\u3087\u3046\u304c\u3001\u3069\u308c\u3082\u4f53\u91cd\u6e1b\u5c11\u3001\u4e2d\u6027\u8102\u80aa\u6e1b\u5c11\u3092\u793a\u3057\u307e\u3059\u30021\u65e5\u304a\u304d\u306e\u9694\u65e5\u65ad\u98df\u304c\u6700\u3082\u52b9\u679c\u304c\u3042\u308b\u3088\u3046\u3067\u3059\u3002\uff08\u79c1\u306f\u3042\u307e\u308a\u3084\u308a\u305f\u304f\u306a\u3044\u65b9\u6cd5\u3067\u3059\u306d\uff09\u4e2d\u6027\u8102\u80aa\u306e\u6e1b\u5c11\u306f\u4f53\u91cd\u6e1b\u5c11\u3068\u95a2\u9023\u3057\u3066\u3044\u3066\u3001\u9031\u306b1kg\u6e1b\u5c11\u3059\u308b\u306830\uff5e40\uff05\u4e2d\u6027\u8102\u80aa\u304c\u6e1b\u5c11\u3059\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">Clinical Summary: Higher-fat, lower-carbohydrate diets are associated with greater reduction in triglycerides as a response to weight loss compared with lower-fat, higher-carbohydrate diets. All carbohydrate-restricted diets result in significant and similar weight loss, but the reduction in triglycerides is greatest for a very-low-carbohydrate diet. Overall, evidence supports that a higher-protein diet is associated with greater weight loss and reduction in triglycerides, but there is some inconsistency in current data that may reflect the accompanying changes in carbohydrate or fat. Triglycerides are reduced with intermittent fasting in proportion to weight loss.<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u81e8\u5e8a\u7684\u6982\u8981\uff1a\u9ad8\u8102\u80aa\u4f4e\u70ad\u6c34\u5316\u7269\u98df\u306f\u3001\u4f4e\u8102\u80aa\u9ad8\u70ad\u6c34\u5316\u7269\u98df\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4f53\u91cd\u6e1b\u5c11\u3078\u306e\u53cd\u5fdc\u3068\u3057\u3066\u4e2d\u6027\u8102\u80aa\u306e\u5927\u5e45\u306a\u6e1b\u5c11\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u70ad\u6c34\u5316\u7269\u5236\u9650\u98df\u306f\u3001\u6709\u610f\u3067\u540c\u69d8\u306e\u4f53\u91cd\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u304c\u3001\u4e2d\u6027\u8102\u80aa\u306e\u6e1b\u5c11\u306f\u3001\u975e\u5e38\u306b\u4f4e\u70ad\u6c34\u5316\u7269\u306e\u98df\u4e8b\u3067\u6700\u5927\u3067\u3059\u3002\u5168\u4f53\u3068\u3057\u3066\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u306f\u4e2d\u6027\u8102\u80aa\u306e\u5927\u5e45\u306a\u4f53\u91cd\u6e1b\u5c11\u3068\u6e1b\u5c11\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u8a3c\u62e0\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u70ad\u6c34\u5316\u7269\u307e\u305f\u306f\u8102\u80aa\u306e\u5909\u5316\u3092\u53cd\u6620\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u73fe\u5728\u306e\u30c7\u30fc\u30bf\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u77db\u76fe\u304c\u3042\u308a\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u6bd4\u4f8b\u3057\u3066\u65ad\u7d9a\u7684\u65ad\u98df\u3067\u6e1b\u5c11\u3057\u307e\u3059\u3002<\/span><\/p>\n<p>\u305d\u306e1\u3067\u66f8\u304b\u308c\u305f\u3053\u3068\u3068\u4eca\u56de\u306e\u5185\u5bb9\u306e\u307e\u3068\u3081\u3067\u3059\u304c\u3001\u7cd6\u8cea\u5236\u9650\u98df\u306f\u4f53\u91cd\u6e1b\u5c11\u3001\u4e2d\u6027\u8102\u80aa\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3057\u3001\u975e\u5e38\u306b\u4f4e\u70ad\u6c34\u5316\u7269\u98df\u306b\u3059\u308b\u3068\u305d\u306e\u6e1b\u5c11\u306f\u6700\u5927\u306b\u306a\u308b\u3068\u8a00\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u3088\u308b\u4e2d\u6027\u8102\u80aa\u6e1b\u5c11\u306b\u3064\u3044\u3066\u306f\u70ad\u6c34\u5316\u7269\uff08\u8102\u8cea\uff09\u306e\u6442\u53d6\u91cf\u306e\u5909\u5316\u306b\u3088\u3063\u3066\u8d77\u304d\u305f\u3082\u306e\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u8a00\u3063\u3066\u3044\u307e\u3059\u3002\u79c1\u3082\u305d\u3046\u601d\u3044\u307e\u3059\u3002\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u304c\u4e2d\u6027\u8102\u80aa\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3044\u3046\u3088\u308a\u3082\u305d\u308c\u306b\u4f34\u3046\u70ad\u6c34\u5316\u7269\u306e\u6e1b\u5c11\u306e\u65b9\u304c\u5927\u304d\u306a\u52b9\u679c\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">A recent review of very-low-carbohydrate and ketogenic diets and cardiometabolic risk reported that triglyceride levels are inversely associated with carbohydrate intake (importantly, it was also noted that very-low-carbohydrate and ketogenic diets increase LDL-C, markedly in some patients). The 2013 AHA\/ACC guideline on lifestyle management to reduce cardiovascular risk summarized the effects of substituting various macronutrients on triglycerides.<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u8d85\u4f4e\u70ad\u6c34\u5316\u7269\u98df\u3068\u30b1\u30c8\u30f3\u98df\u7642\u6cd5\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u4ee3\u8b1d\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u4e2d\u6027\u8102\u80aa\u5024\u306e\u4f4e\u4e0b\u304c\u70ad\u6c34\u5316\u7269\u6442\u53d6\u91cf\u3068\u9006\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u91cd\u8981\u306a\u3053\u3068\u306b\u3001\u8d85\u4f4e\u70ad\u6c34\u5316\u7269\u98df\u3068\u30b1\u30c8\u30f3\u98df\u306fLDL-\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059 \uff09\u3002\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u305f\u3081\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u7ba1\u7406\u306b\u95a2\u3059\u308b2013\u5e74\u306eAHA \/ ACC\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306f\u3001\u4e2d\u6027\u8102\u80aa\u306b\u5bfe\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u4e3b\u8981\u6804\u990a\u7d20\u306e\u4ee3\u66ff\u306e\u5f71\u97ff\u3092\u8981\u7d04\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>\u3053\u3053\u3067\u3082\u3001\u7cd6\u8cea\u5236\u9650\u98df\u3084\u30b1\u30c8\u30f3\u98df\u306b\u304a\u3044\u3066\u70ad\u6c34\u5316\u7269\u6442\u53d6\u91cf\u304c\u4e2d\u6027\u8102\u80aa\u3068\u9006\u76f8\u95a2\u3001\u3064\u307e\u308a\u70ad\u6c34\u5316\u7269\u6442\u53d6\u91cf\u3092\u6e1b\u3089\u305b\u3070\u4e2d\u6027\u8102\u80aa\u5024\u304c\u6e1b\u5c11\u3059\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u7cd6\u8cea\u5236\u9650\u3084\u30b1\u30c8\u30f3\u98df\u304cLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u3042\u308b\u3053\u3068\u3092\u6307\u6458\u3059\u308b\u3053\u3068\u3092\u5fd8\u308c\u3066\u3044\u307e\u305b\u3093\u306d\u3002\u3057\u304b\u3057\u3001\u91cd\u8981\u3068\u306f\u8a00\u3044\u306a\u304c\u3089\u30ab\u30c3\u30b3\u306e\u4e2d\u306e\u8a18\u8ff0\u3067\u3042\u308a\u3001\u63a7\u3048\u3081\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u306e\u306f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u91cd\u8981\u6027\u304c\u9ad8\u304f\u306a\u3044\u3053\u3068\u3092\u8a8d\u3081\u305f\u3088\u3046\u306b\u3082\u611f\u3058\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">Carbohydrate, Protein, and Fat<\/span><br \/>\n<span style=\"color: #3366ff;\">For every 1% of energy from saturated fatty acids that is replaced by 1% of energy from either carbohydrates (not refined nor added sugars, but fiber-rich, complex carbohydrates) or monounsaturated fatty acids, triglycerides increased \u22481.9 and 0.2 mg\/dL, respectively. In contrast, when PUFAs are the replacement nutrient, triglycerides are lowered by about 0.4 mg\/dL.<\/span><\/p>\n<p><span style=\"color: #3366ff;\">When 1% of energy from carbohydrates is replaced by 1% of energy from monosaturated fatty acids (MUFAs), triglycerides are lowered by 1.7 mg\/dL; when PUFAs are the replacement nutrient, triglycerides are lowered by 2.3 mg\/dL. Modification to the Dietary Approaches to Stop Hypertension dietary pattern by replacing 10% of calories from carbohydrates with 10% of calories from unsaturated fat (8% MUFAs and 2% PUFAs) lowered triglycerides by 10 mg\/dL; replacing 10% of calories from carbohydrates with 10% of calories from protein lowered triglycerides by 16 mg\/dL. A dose-response effect of dietary carbohydrate on triglyceride levels has been reported: triglycerides decreased by \u221223.9 mg\/dL (95% CI: \u221238.1 to \u22128.9 mg\/dL) on a very-low-carbohydrate diet (3% to 30% of energy), by \u221215.9 mg\/dL (95% CI: \u221223.0 to \u22129.7 mg\/dL) on low-carbohydrate diets (30% to 40% of energy), and by \u22128.9 mg\/dL (95% CI: \u221212.4 to -5.3 mg\/dL) on the moderately-low-carbohydrate diets (40% to 45% of energy).<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u70ad\u6c34\u5316\u7269\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u8102\u80aa<\/span><br \/>\n<span style=\"color: #3366ff;\">\u98fd\u548c\u8102\u80aa\u9178\u304b\u3089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306e1\uff05\u3054\u3068\u306b\u3001\u70ad\u6c34\u5316\u7269\uff08\u7cbe\u88fd\u7cd6\u3084\u6dfb\u52a0\u7cd6\u3067\u306f\u306a\u304f\u3001\u7e4a\u7dad\u304c\u8c4a\u5bcc\u306a\u8907\u5408\u70ad\u6c34\u5316\u7269\uff09\u307e\u305f\u306f\u4e00\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u304b\u3089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306e1\uff05\u306b\u7f6e\u304d\u63db\u3048\u3089\u308c\u308b\u3068\u3001\u4e2d\u6027\u8102\u80aa\u306f\u305d\u308c\u305e\u308c\u7d041.9\u304a\u3088\u30730.2 mg \/ dL\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u5bfe\u7167\u7684\u306b\u3001\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306b\u4ee3\u66ff\u3057\u305f\u5834\u5408\u3001\u4e2d\u6027\u8102\u80aa\u306f\u7d040.4 mg \/ dL\u4f4e\u4e0b\u3057\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u70ad\u6c34\u5316\u7269\u304b\u3089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306e1\uff05\u304c\u4e00\u4fa1\u98fd\u548c\u8102\u80aa\u9178\u304b\u3089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306e1\uff05\u306b\u7f6e\u304d\u63db\u3048\u3089\u308c\u308b\u3068\u3001\u4e2d\u6027\u8102\u80aa\u306f1.7 mg \/ dL\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306b\u4ee3\u66ff\u3057\u305f\u5834\u5408\u3001\u4e2d\u6027\u8102\u80aa\u306f2.3 mg \/ dL\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u70ad\u6c34\u5316\u7269\u304b\u3089\u306e\u30ab\u30ed\u30ea\u30fc\u306e10\uff05\u3092\u4e0d\u98fd\u548c\u8102\u80aa\u304b\u3089\u306e\u30ab\u30ed\u30ea\u30fc\u306e10\uff05\uff088\uff05\u4e00\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u304a\u3088\u30732\uff05\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\uff09\u306b\u7f6e\u304d\u63db\u3048\u308b\u3053\u3068\u306b\u3088\u308b\u3001DASH\u98df\u7642\u6cd5\u306f\u3001\u4e2d\u6027\u8102\u80aa\u309210 mg \/ dL\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002\u70ad\u6c34\u5316\u7269\u306e\u30ab\u30ed\u30ea\u30fc\u306e10\uff05\u3092\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30ab\u30ed\u30ea\u30fc\u306e10\uff05\u306b\u7f6e\u304d\u63db\u3048\u308b\u3068\u3001\u4e2d\u6027\u8102\u80aa\u304c16 mg \/ dL\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u4e2d\u6027\u8102\u80aa\u306b\u5bfe\u3059\u308b\u98df\u4e8b\u6027\u70ad\u6c34\u5316\u7269\u306e\u7528\u91cf\u53cd\u5fdc\u52b9\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u4e2d\u6027\u8102\u80aa\u306f\u3001\u8d85\u4f4e\u70ad\u6c34\u5316\u7269\u98df\uff08\u6442\u53d6\u30a8\u30cd\u30eb\u30ae\u30fc\u306e3\uff5e30<\/span><span style=\"color: #3366ff;\">\uff05<\/span><span style=\"color: #3366ff;\">\uff09\u3067-23.9mg \/ dL\uff0895\uff05CI\uff1a-38.1\u304b\u3089-8.9mg \/ dL\uff09\u6e1b\u5c11\u3057\u3001\u4f4e\u70ad\u6c34\u5316\u7269\u98df\uff08\u30a8\u30cd\u30eb\u30ae\u30fc\u306e30\uff05\uff5e40\uff05\uff09\u3067-15.9mg \/ dL\uff0895\uff05CI\uff1a-23.0\u304b\u3089-9.7mg \/ dL\uff09\u6e1b\u5c11\u3001\u304a\u3088\u3073<\/span><span style=\"color: #3366ff;\">\u4e2d\u7a0b\u5ea6\u306e\u4f4e\u70ad\u6c34\u5316\u7269\u98df\uff08\u30a8\u30cd\u30eb\u30ae\u30fc\u306e40\uff05\uff5e45\uff05\uff09<\/span><span style=\"color: #3366ff;\">-8.9mg \/ dL\uff0895\uff05CI\uff1a\u3067-12.4\u304b\u3089-5.3mg \/ dL\uff09\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002<\/span><\/p>\n<p>\u3064\u307e\u308a\u3001\u7c21\u5358\u306b\u8a00\u3048\u3070\u70ad\u6c34\u5316\u7269\u3092\u8102\u8cea\u306b\u7f6e\u304d\u63db\u3048\u308b\u5272\u5408\u304c\u591a\u3044\u307b\u3069\u4e2d\u6027\u8102\u80aa\u306f\u4f4e\u4e0b\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u7cd6\u8cea\u3092\u6e1b\u3089\u3057\u3001\u8102\u8cea\u3092\u5897\u3084\u305b\u3070\u4e2d\u6027\u8102\u80aa\u306f\u4f4e\u4e0b\u3059\u308b\u306e\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306f\u4e2d\u7a0b\u5ea6\u306e\u7cd6\u8cea\u5236\u9650\u3067\u3082\u591a\u5c11\u3057\u307e\u3059\u304c\u3001\u3084\u306f\u308a\u3057\u3063\u304b\u308a\u3068\u7cd6\u8cea\u5236\u9650\u3092\u3057\u305f\u65b9\u304c\u4f4e\u4e0b\u91cf\u306f\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">Clinical Summary: Meaningful reductions in triglycerides can be achieved by decreasing the carbohydrate content of the diet. When lowering total cholesterol in the diet to reduce triglyceride levels in patients with hypertriglyceridemia, the total fat content should be adjusted according to baseline triglyceride levels. It is important to keep in mind that when dietary carbohydrates are reduced, there is usually a decrease in dietary fiber intake. Clinicians should address strategies to maintain a healthy intake of fiber by replacing refined grains (white bread, white rice, pasta) with fiber-rich, whole grain cereals and bread, and brown rice.<\/span><\/p>\n<p><span style=\"color: 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style=\"color: #3366ff;\">\u300c2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia: A Report of the American College of Cardiology Solution Set Oversight Committee\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u6301\u7d9a\u6027\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u60a3\u8005\u306b\u304a\u3051\u308bASCVD\u30ea\u30b9\u30af\u4f4e\u6e1b\u306e\u7ba1\u7406\u306b\u95a2\u3059\u308b2021\u5e74ACC\u5c02\u9580\u5bb6\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9\u6c7a\u5b9a\u7d4c\u8def\uff1a\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u75c5\u5b66\u4f1a\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u30bb\u30c3\u30c8\u76e3\u8996\u59d4\u54e1\u4f1a\u306e\u5831\u544a\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34332805\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u75c5\u5b66\u4f1a\u306f\u4e2d\u6027\u8102\u80aa\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u98df\u4e8b\u3068\u3057\u3066\u7cd6\u8cea\u5236\u9650\u3092\u63d0\u5531\u3057\u307e\u3057\u305f\u3002\u524d\u56de\u306e\u8a18\u4e8b\u300c\u305d\u306e1\u300d\u306e\u7d9a\u304d\u3067\u3059\u3002 High-protein diets: A higher-protein diet is defined as<\/p>\n","protected":false},"author":1,"featured_media":16611,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,145,144,10],"tags":[19,24,46],"class_list":["post-16592","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-ldl","category-cholesterol","category-10","tag-toushitsuseigen","tag-cholesterol","tag-fat","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/5162953_s.jpg?fit=640%2C427&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-4jC","jetpack-related-posts":[{"id":16574,"url":"https:\/\/promea2014.com\/blog\/?p=16574","url_meta":{"origin":16592,"position":0},"title":"\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u75c5\u5b66\u4f1a\u306f\u4e2d\u6027\u8102\u80aa\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u4ecb\u5165\u3068\u3057\u3066\u7cd6\u8cea\u5236\u9650\u3092\u63d0\u5531\u3000\u305d\u306e1","author":"Dr.Shimizu","date":"2021\u5e748\u670810\u65e5","format":false,"excerpt":"\u307e\u305f\u30a2\u30e1\u30ea\u30ab\u306f\u7cd6\u8cea\u5236\u9650\u3092\u63a8\u5968\u3059\u308b\u52d5\u304d\u304c\u5f37\u307e\u308a\u307e\u3057\u305f\u3002\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u30a2\u30e1\u30ea\u30ab\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u304c\u51fa\u3057\u305f\u6b74\u53f2\u7684\u306a\u30b3\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/10001075_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/10001075_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 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