{"id":17015,"date":"2021-10-06T17:52:58","date_gmt":"2021-10-06T08:52:58","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=17015"},"modified":"2021-10-06T17:58:02","modified_gmt":"2021-10-06T08:58:02","slug":"post-17015","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=17015","title":{"rendered":"\u30b1\u30c8\u30f3\u4f53\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u80a5\u6e80\u306e\u8133\u6a5f\u80fd\u3092\u6539\u5584\u3059\u308b\u304b\u3082\u3057\u308c\u306a\u3044"},"content":{"rendered":"<p>\u80a5\u6e80\u306e\u4eba\u306f\u3001\u8133\u8840\u6d41\u306e\u4f4e\u4e0b\u3068\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff08BDNF\uff09\u306e\u6e1b\u5c11\u306a\u3069\u306b\u3088\u308a\u7d50\u679c\u3001\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u8133\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306f\u30d6\u30c9\u30a6\u7cd6\u3067\u3059\u304c\u3001\u8a8d\u77e5\u75c7\u3067\u306f\u8133\u306e\u30d6\u30c9\u30a6\u7cd6\u306e\u53d6\u8fbc\u307f\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u305d\u306e\u5834\u5408\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3057\u3066\u3044\u308c\u3070\u30b1\u30c8\u30f3\u4f53\u304c\u751f\u6210\u3055\u308c\u306a\u3044\u306e\u3067\u3001\u8133\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u4e0d\u8db3\u306b\u9665\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u305d\u3093\u306a\u80a5\u6e80\u306e\u4eba\u306b\u30b1\u30c8\u30f3\u4f53\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u98f2\u3093\u3067\u3082\u3089\u3063\u305f\u3089\u3069\u3046\u306a\u308b\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u306f\u300130\u301c69\u6b73\u3067\u3001\u5c11\u306a\u304f\u3068\u3082\u8179\u56f2\u304c\u7537\u6027\u3067102cm\u3001\u5973\u6027\u306788cm\u3088\u308a\u5927\u304d\u3044\u304b\u3001BMI\u304c30\u3088\u308a\u5927\u304d\u3044\u304b\u3001\u524d\u7cd6\u5c3f\u75c5\uff08\u7cd6\u5c3f\u75c5\u4e88\u5099\u8ecd\uff09\u306e\u3069\u308c\u304b\u4e00\u3064\u306b\u5f53\u3066\u306f\u307e\u308b\u4eba\u3067\u3059\u3002\u5b9f\u969b\u306e\u53c2\u52a0\u8005\u306f\u7537\u60274\u4eba\u3001\u5973\u602710\u4eba\u3067\u3001\u5e73\u5747\u5e74\u9f6255.8\u6b73\u3001\u5e73\u5747BMI\u306f33.8\u3067\u3057\u305f\u3002\u6bd4\u8f03\u7684\u82e5\u3044\u96c6\u56e3\u3067\u3059\u3002\u671d\u98df\u3001\u663c\u98df\u3001\u5915\u98df\u306e15\u5206\u524d\u306b\u3001\u30b1\u30c8\u30f3\u4f53\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u309214\u65e5\u9593\u6442\u53d6\u3057\u3066\u3082\u3089\u3044\u307e\u3057\u305f\u3002\u30b1\u30c8\u30f3\u4f53\u306e\u30b5\u30d7\u30ea\u306f0.4g\/mL\u306e\u03b2-OHB\uff08\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178\uff09\u3092\u542b\u3093\u3060\u3082\u306e\u3067\u30011\u65e5\u3042\u305f\u308a36g\u306e\u03b2-OHB\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u98df\u4e8b\u306f\u63d0\u4f9b\u3055\u308c\u3001\u70ad\u6c34\u5316\u7269\u7d0450\uff05\u3001\u8102\u8cea30\uff05\u3001\u30bf\u30f3\u30d1\u30af\u8cea20\uff05\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<header class=\"article-table-caption\"><\/header>\n<div class=\"article-table-content-wrapper\">\n<table class=\"table article-section__table\">\n<thead>\n<tr>\n<th class=\"right-bordered-cell left-aligned\"><\/th>\n<th class=\"center-aligned\">\u5168\u4f53<\/th>\n<th class=\"center-aligned\">\u5973\u6027<\/th>\n<th class=\"center-aligned\">\u7537<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u5e74\u9f62\uff08\u5e74\uff09<\/td>\n<td class=\"center-aligned\">55.8\uff0812.4\uff09<\/td>\n<td class=\"center-aligned\">59.0\uff088.2\uff09<\/td>\n<td class=\"center-aligned\">47.8\uff0818.4\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u4f53\u91cd\uff08kg\uff09<\/td>\n<td class=\"center-aligned\">95.1\uff0822.2\uff09<\/td>\n<td class=\"center-aligned\">91.5\uff0825.2\uff09<\/td>\n<td class=\"center-aligned\">104.0\uff088.8\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">BMI<\/td>\n<td class=\"center-aligned\">33.8\uff086.9\uff09<\/td>\n<td class=\"center-aligned\">34.1\uff088.2\uff09<\/td>\n<td class=\"center-aligned\">33.1\uff081.5\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u80f4\u56f2\uff08cm\uff09<\/td>\n<td class=\"center-aligned\">109.2\uff0817.1\uff09<\/td>\n<td class=\"center-aligned\">108.4\uff0820.4\uff09<\/td>\n<td class=\"center-aligned\">111.3\uff081.7\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u53ce\u7e2e\u671f\u8840\u5727\uff08mmHg\uff09<\/td>\n<td class=\"center-aligned\">132\uff0818\uff09<\/td>\n<td class=\"center-aligned\">134\uff0819\uff09<\/td>\n<td class=\"center-aligned\">128\uff0817\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u62e1\u5f35\u671f\u8840\u5727\uff08mmHg\uff09<\/td>\n<td class=\"center-aligned\">81\uff0811\uff09<\/td>\n<td class=\"center-aligned\">84\uff0810\uff09<\/td>\n<td class=\"center-aligned\">74\uff0813\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u8840\u7cd6\u5024\uff08mmol\/L\uff09<\/td>\n<td class=\"center-aligned\">4.74\uff080.49\uff09<\/td>\n<td class=\"center-aligned\">4.61\uff080.32\uff09<\/td>\n<td class=\"center-aligned\">4.96\uff080.35\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">\u30a4\u30f3\u30b9\u30ea\u30f3\uff08uIU\/mL\uff09<\/td>\n<td class=\"center-aligned\">21.58\uff0813.41\uff09<\/td>\n<td class=\"center-aligned\">20.11\uff0814.51\uff09<\/td>\n<td class=\"center-aligned\">25.27\uff0810.78\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">C-\u30da\u30d7\u30c1\u30c9\uff08pmol\/L\uff09<\/td>\n<td class=\"center-aligned\">2324.2\uff081112.5\uff09<\/td>\n<td class=\"center-aligned\">2404.6\uff081219.2\uff09<\/td>\n<td class=\"center-aligned\">2123.4\uff08910.2\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\">NEFA\uff08mmol\/L\uff09<\/td>\n<td class=\"center-aligned\">0.63\uff080.15\uff09<\/td>\n<td class=\"center-aligned\">0.66\uff080.15\uff09<\/td>\n<td class=\"center-aligned\">0.54\uff080.14\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u4e0a\u306e\u8868\u306f\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u7279\u5fb4\u3067\u3059\u3002\u80a5\u6e80\u3067\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3\u306f20\u4ee5\u4e0a\u3068\u9ad8\u3044\u3067\u3059\u3002<\/p>\n<div class=\"article-table-content-wrapper\">\n<table class=\"table article-section__table\" style=\"width: 90.4412%;\">\n<thead>\n<tr>\n<th class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\"><\/th>\n<th class=\"center-aligned\" style=\"width: 211px;\">\u30d7\u30e9\u30bb\u30dc\uff08<i>n<\/i>\u00a0\u00a0= 14\uff09<\/th>\n<th class=\"center-aligned\" style=\"width: 221px;\">\u30b1\u30c8\u30f3\u30b5\u30d7\u30ea\uff08<i>n<\/i>\u00a0\u00a0= 14\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">\u4f53\u91cd\uff08kg\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\"><span style=\"color: #ff0000;\">\u22121.08\uff08\u22121.77\u301c\u22120.39\uff09<\/span><\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\"><span style=\"color: #ff0000;\">\u22120.97\uff08\u22121.66\u301c\u22120.28\uff09<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">BMI<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\"><span style=\"color: #ff0000;\">\u22120.46\uff08\u22120.72\u301c\u22120.21\uff09<\/span><\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\"><span style=\"color: #ff0000;\">\u22120.39\uff08\u22120.65\u301c\u22120.13\uff09<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">\u80f4\u56f2\uff08cm\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\">\u22120.01\uff08\u22121.74\u301c1.71\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\">\u22121.2\uff08\u22122.9\u301c0.51\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">\u8840\u7cd6\u5024\uff08mmol\/L\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\">0.10\uff08-0.18\u301c0.38\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\">0.21\uff08-0.14\u301c0.55\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">\u30a4\u30f3\u30b9\u30ea\u30f3\uff08uIU\/mL\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\">\u22122.38\uff08\u221223.16\u301c18.40\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\">\u221216.78\uff08\u221252.48\u301c18.93\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">C-\u30da\u30d7\u30c1\u30c9\uff08pmol\/L\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\">4.77\uff08-647.7\u304b\u3089657.3\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\">\u2212364.5\uff08\u2212962.3\u301c233.4\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 183px;\">NEFA\uff08mmol\/L\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 211px;\"><span style=\"color: #ff0000;\">\u22120.15\uff08\u22120.32\u301c0.02\uff09<\/span><\/td>\n<td class=\"center-aligned\" style=\"width: 221px;\"><span style=\"color: #ff0000;\">\u22120.11\uff08\u22120.25\u301c0.02\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u4e0a\u306e\u8868\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u30b1\u30c8\u30f3\u4f53\u306e\u30b5\u30d7\u30ea\u3092\u98f2\u3093\u3060\u5f8c\u306e\u5e73\u5747\u306e\u5909\u5316\u91cf\u3067\u3059\u3002\u30d7\u30e9\u30bb\u30dc\u3067\u3082\u4f53\u91cd\u3084BMI\u304c\u4f4e\u4e0b\u3057\u305f\u306e\u306f\u30013\u98df\u3068\u3082\u98df\u4e8b\u3092\u63d0\u4f9b\u3055\u308c\u305f\u304b\u3089\u3067\u3057\u3087\u3046\u3002\u6709\u610f\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u30b1\u30c8\u30f3\u4f53\u306e\u30b5\u30d7\u30ea\u306e\u65b9\u304c\u30a4\u30f3\u30b9\u30ea\u30f3\u304a\u3088\u3073C-\u307a\u30d7\u30c1\u30c9\u304c\u5927\u304d\u304f\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u4eba\u304c\u591a\u3044\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n<header class=\"article-table-caption\"><\/header>\n<div class=\"article-table-content-wrapper\">\n<table class=\"table article-section__table\" style=\"width: 680px;\">\n<thead>\n<tr>\n<th class=\"right-bordered-cell left-aligned\" style=\"width: 192px;\"><\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 244px;\" colspan=\"2\">\u30d7\u30e9\u30bb\u30dc\uff08<i>n<\/i>\u00a0\u00a0= 14\uff09<\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 244px;\" colspan=\"2\">\u30b1\u30c8\u30f3\u4f53\uff08<i>n<\/i>\u00a0\u00a0= 14\uff09<\/th>\n<\/tr>\n<tr>\n<th class=\"bottom-bordered-cell right-bordered-cell left-aligned\" style=\"width: 192px;\"><\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 122px;\">\u524d<\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 122px;\">\u5f8c<\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 122px;\">\u524d<\/th>\n<th class=\"bottom-bordered-cell center-aligned\" style=\"width: 122px;\">\u5f8c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 192px;\">\u6570\u5b57\u7b26\u53f7\u7f6e\u63db\u691c\u67fb\uff08\u6b63\u3057\u3044\u6570\u5b57\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">37.1\uff088.7\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">38.8\uff087.1\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\"><span style=\"color: #ff0000;\">38.6\uff087.4\uff09<\/span><\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\"><span style=\"color: #ff0000;\">40.9\uff087.8\uff09<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 192px;\">\u30bf\u30b9\u30af\u5207\u308a\u66ff\u3048\uff08ms\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">208.3\uff08162.7\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">175.1\uff08106.9\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">216.4\uff08142.2\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">185.0\uff08150.4\uff09<\/td>\n<\/tr>\n<tr>\n<td class=\"right-bordered-cell left-aligned\" style=\"width: 192px;\">\u30b9\u30c8\u30eb\u30fc\u30d7\u30bf\u30b9\u30af\uff08\u30df\u30ea\u79d2\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">195.6\uff08104.3\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">185.7\uff0883.5\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">220.1\uff08174.8\uff09<\/td>\n<td class=\"center-aligned\" style=\"width: 122px;\">199.5\uff08103.2\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u6570\u5b57\u7b26\u53f7\u7f6e\u63db\u691c\u67fbdigit symbol substitution task (DSST)\u306a\u3069\u306e\u8a73\u7d30\u306f\u7701\u7565\u3057\u307e\u3059\u304c\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u30c6\u30b9\u30c8\u3067\u3059\u3002\u6570\u5b57\u7b26\u53f7\u7f6e\u63db\u691c\u67fb\u306f\u30b1\u30c8\u30f3\u4f53\u30b5\u30d7\u30ea\u3067\u5927\u5e45\u306b\u6539\u5584\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u4ed6\u306e\u30c6\u30b9\u30c8\u306f\u6709\u610f\u306a\u5909\u5316\u304c\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/a0e066b1274c297b85c1caf53bf6042f.webp\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17023\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17023\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/a0e066b1274c297b85c1caf53bf6042f.webp?fit=320%2C500&amp;ssl=1\" data-orig-size=\"320,500\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u30b1\u30c8\u30f3\u30b5\u30d7\u30ea\u8133\u8840\u6d41tjp14839-fig-0002-m\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/a0e066b1274c297b85c1caf53bf6042f.webp?fit=192%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/a0e066b1274c297b85c1caf53bf6042f.webp?fit=320%2C500&amp;ssl=1\" class=\"alignnone size-full wp-image-17023\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/a0e066b1274c297b85c1caf53bf6042f.webp?resize=320%2C500\" alt=\"\" width=\"320\" height=\"500\" 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style=\"color: #3366ff;\">\u300cShort-term ketone monoester supplementation improves cerebral blood flow and cognition in obesity: A randomized cross-over trial\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u77ed\u671f\u9593\u306e\u30b1\u30c8\u30f3\u30e2\u30ce\u30a8\u30b9\u30c6\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3001\u80a5\u6e80\u306b\u304a\u3051\u308b\u8133\u8840\u6d41\u3068\u8a8d\u77e5\u3092\u6539\u5584\u3059\u308b\uff1a\u30e9\u30f3\u30c0\u30e0\u5316\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u8a66\u9a13\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/full\/10.1113\/JP281988\" target=\"_blank\" 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