{"id":17436,"date":"2021-11-25T08:26:41","date_gmt":"2021-11-24T23:26:41","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=17436"},"modified":"2021-11-25T08:26:41","modified_gmt":"2021-11-24T23:26:41","slug":"post-17436","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=17436","title":{"rendered":"\u8102\u80aa\u809d\u306f\u809d\u81d3\u304c\u3093\u3078\u9032\u884c\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b"},"content":{"rendered":"<p>\u591a\u304f\u306e\u4eba\u306f\u8102\u80aa\u809d\u3092\u6307\u6458\u3055\u308c\u308b\u3068\u3001\u82e6\u7b11\u3057\u305f\u3088\u3046\u306a\u8868\u60c5\u3001\u53cd\u5fdc\u3092\u793a\u3057\u307e\u3059\u3002\u3061\u3087\u3063\u3068\u6065\u305a\u304b\u3057\u3044\u306e\u304b\u3001\u300c\u592a\u3063\u3066\u3044\u308b\u300d\u3068\u6307\u6458\u3055\u308c\u305f\u3088\u3046\u306a\u611f\u3058\u306a\u306e\u304b\u3001\u6df1\u523b\u3055\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\uff08NAFLD\uff09\u3092\u653e\u7f6e\u3059\u308b\u3053\u3068\u306f\u5f53\u7136\u826f\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u307e\u307e\u3067\u306f\u9032\u884c\u3057\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u809d\u81d3\u304c\u3093\u307e\u3067\u9032\u884c\u3059\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u304b\u3089\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17453\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17453\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?fit=742%2C367&amp;ssl=1\" data-orig-size=\"742,367\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u8102\u80aa\u809dijms-17-00774-g001\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?fit=300%2C148&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?fit=640%2C317&amp;ssl=1\" class=\"alignnone size-full wp-image-17453\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?resize=640%2C317\" alt=\"\" width=\"640\" height=\"317\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?w=742&amp;ssl=1 742w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?resize=300%2C148&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/3caae56ea9b9ada5c9e485fcf73b0886.jpg?resize=320%2C158&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\uff08NAFLD\uff09\u306f\u305d\u306e\u307e\u307e\u3060\u3068\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u708e\uff08NASH\uff09\u3068\u3044\u3046\u72b6\u614b\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001\u305d\u306e\u4e2d\u3067\u3082\u809d\u7dda\u7dad\u75c7\u3092\u4f34\u3046\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u3046\u3061\u4f55\u5272\u304b\u306f\u809d\u786c\u5909\u3078\u3068\u9032\u884c\u3057\u3001\u305d\u306e\u3046\u3061\u4f55\u5272\u304b\u306f\u809d\u81d3\u304c\u3093\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u809d\u786c\u5909\u306b\u306a\u3089\u306a\u304f\u3066\u3082\u809d\u81d3\u304c\u3093\u306b\u9032\u884c\u3059\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\uff08NAFLD\uff09\u306b\u95a2\u9023\u3057\u305f\u809d\u81d3\u304c\u3093\u60a3\u8005\u306e\u304a\u3088\u305d\u534a\u5206\u306f\u809d\u786c\u5909\u3092\u4f34\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u305d\u3046\u3059\u308b\u3068\u767a\u898b\u304c\u9045\u304f\u306a\u308a\u3001\u3088\u308a\u304c\u3093\u304c\u5927\u304d\u304f\u306a\u3063\u305f\u308a\u30b9\u30c6\u30fc\u30b8\u304c\u9032\u3093\u3060\u72b6\u614b\u3067\u767a\u898b\u3055\u308c\u308b\u53ef\u80fd\u6027\u3082\u9ad8\u304f\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\uff08\u56f3\u306f<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34674650\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u3088\u308a\u3001\u8868\u306f\u6539\u5909\uff09<\/p>\n<div class=\"caption\">\n<p id=\"idm140200054585088\"><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17454\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17454\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?fit=795%2C351&amp;ssl=1\" data-orig-size=\"795,351\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u8102\u80aa\u809d\u809d\u81d3\u304c\u309312876_2021_1978_Fig1_HTML\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?fit=300%2C132&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?fit=640%2C283&amp;ssl=1\" class=\"alignnone size-full wp-image-17454\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?resize=640%2C283\" alt=\"\" width=\"640\" height=\"283\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?w=795&amp;ssl=1 795w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?resize=300%2C132&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?resize=768%2C339&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/11\/4dd0f9db5bc40685f3188669a0137bb7.jpg?resize=320%2C141&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306fNAFLD\u60a3\u80051\u4e07\u4eba\u5f53\u305f\u308a\u306e\u809d\u81d3\u304c\u3093\u306e\u6709\u75c5\u7387\u3067\u3059\u3002\u4e00\u756a\u4e0a\u304c\u975e\u809d\u786c\u5909\u3001\u305d\u306e\u4e0b\u304c\u975e\u809d\u786c\u5909\u3067\u7537\u6027\u300165\u6b73\u4ee5\u4e0a\u3001\u55ab\u7159\u3001\u7cd6\u5c3f\u75c5\u3001ALT\u4e0a\u6607\uff08\u5177\u4f53\u7684\u306a\u6570\u5024\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u6050\u3089\u304f\u306f\u57fa\u6e96\u5024\u306e45\u4ee5\u4e0a\u3060\u3068\u601d\u3044\u307e\u3059\uff09\u304c\u3042\u308b\u5834\u5408\u30013\u756a\u76ee\u304c\u305d\u308c\u306b\u52a0\u3048\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u4f7f\u7528\u306e\u5834\u5408\u3001\u4e00\u756a\u4e0b\u304c\u809d\u786c\u5909\u3067\u3059\u3002\u975e\u809d\u786c\u5909\u3067\u30825\u3064\u306e\u5371\u967a\u56e0\u5b50\u304c\u52a0\u308f\u308b\u3068\u304a\u3088\u305d10\u500d\u809d\u81d3\u304c\u3093\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u4e0b\u306e\u8868\u306f\u975e\u809d\u786c\u5909NAFLD\u306b\u304a\u3051\u308b\u809d\u81d3\u304c\u3093\u6709\u75c5\u7387\u306b\u95a2\u9023\u3059\u308b\u8981\u56e0\u306e\u591a\u5909\u91cf\u89e3\u6790\u3067\u3059\u3002<\/p>\n<\/div>\n<div class=\"xtable\" data-largeobj=\"\" data-largeobj-link-rid=\"largeobj_idm140200054584720\">\n<table class=\"rendered small default_table\" style=\"width: 77.1722%; height: 347px;\" frame=\"hsides\" rules=\"groups\">\n<thead>\n<tr>\n<th style=\"width: 49.4475%;\" align=\"left\"><\/th>\n<th style=\"width: 50.5525%; text-align: center;\" align=\"left\">\u30aa\u30c3\u30ba\u6bd4<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u5e74\u9f62&gt; 65\u6b73<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\"><span style=\"color: #ff0000;\">3.37<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u7537\u6027<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\"><span style=\"color: #ff0000;\">2.57<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u7cd6\u5c3f\u75c5<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\"><span style=\"color: #ff0000;\">1.56<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u9ad8\u8840\u5727<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\">1.24<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u9ad8\u8102\u8840\u75c7<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\">0.95<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u80a5\u6e80<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\">0.84<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u75c5\u7684\u80a5\u6e80<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\">1.06<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u55ab\u7159\u8005<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\"><span style=\"color: #ff0000;\">1.75<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.4475%;\" align=\"left\">\u9ad8ALT<\/td>\n<td style=\"width: 50.5525%;\" align=\"center\"><span style=\"color: #ff0000;\">2.69<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>65\u6b73\u4ee5\u4e0a\u3001\u7537\u6027\u3001\u7cd6\u5c3f\u75c5\u3001\u55ab\u7159\u3001ALT\u306e\u4e0a\u6607\u306f\u809d\u786c\u5909\u304c\u7121\u304f\u3066\u3082\u8102\u80aa\u809d\u306e\u809d\u81d3\u304c\u3093\u3078\u306e\u9032\u884c\u306e\u53ef\u80fd\u6027\u3092\u9ad8\u3081\u307e\u3059\u3002\u672c\u5f53\u306f\u82e6\u7b11\u3057\u3066\u3044\u308b\u5834\u5408\u3067\u306f\u306a\u304f\u3001\u3059\u3050\u306b\u3067\u3082\u98df\u4e8b\u3092\u6539\u5584\u3059\u3079\u304d\u3067\u3059\u3002\u8102\u80aa\u809d\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u7279\u306b\u679c\u7cd6\u306e\u904e\u5270\u6442\u53d6\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\uff08NAFLD\uff09\u306e\u539f\u56e0\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3092\u6442\u53d6\u3059\u308c\u3070\u809d\u81d3\u306b\u3068\u3063\u3066\u306f\u30c0\u30d6\u30eb\u30d1\u30f3\u30c1\uff08\u8868\u73fe\u304c\u53e4\u3044\uff1f\uff09\u3067\u3059\u3002<\/p>\n<p>\u5f53\u7136\u3001NAFLD\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3042\u308b\u306e\u3067\u3001\u809d\u81d3\u304c\u3093\u4ee5\u5916\u306b\u3082\u305d\u306e\u4ed6\u306e\u304c\u3093\u306e\u30ea\u30b9\u30af\u3082\u5897\u52a0\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\uff08\u305d\u308c\u306b\u3064\u3044\u3066\u306f\u6b21\u56de\u4ee5\u964d\u306b\uff09<\/p>\n<p>\u809d\u81d3\u306b\u8102\u80aa\u304c\u305f\u307e\u3063\u3066\u3044\u308b\u306e\u306f\u304b\u306a\u308a\u5f37\u3044\u4eba\u4f53\u304b\u3089\u306e\u8b66\u544a\u3067\u3059\u3002\u305f\u3060\u306e\u98df\u3079\u3059\u304e\u3001\u80a5\u6e80\u306e\u5146\u5019\u3092\u793a\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u308c\u306b\u6c17\u3065\u3044\u305f\u3068\u304d\u3001\u6307\u6458\u3055\u308c\u305f\u3068\u304d\u306b\u3059\u3050\u306b\u98df\u4e8b\u3092\u6539\u5584\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306f\u500b\u4eba\u305d\u308c\u305e\u308c\u3067\u3059\u3002<\/p>\n<p>\u5148\u5ef6\u3070\u3057\u306b\u3059\u308b\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7cd6\u8cea\u5236\u9650\u3092\u59cb\u3081\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #3366ff;\">\u300cThe Natural Course of Non-Alcoholic Fatty Liver Disease\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\u306e\u81ea\u7136\u7d4c\u904e\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27213358\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u591a\u304f\u306e\u4eba\u306f\u8102\u80aa\u809d\u3092\u6307\u6458\u3055\u308c\u308b\u3068\u3001\u82e6\u7b11\u3057\u305f\u3088\u3046\u306a\u8868\u60c5\u3001\u53cd\u5fdc\u3092\u793a\u3057\u307e\u3059\u3002\u3061\u3087\u3063\u3068\u6065\u305a\u304b\u3057\u3044\u306e\u304b\u3001\u300c\u592a\u3063\u3066\u3044\u308b\u300d\u3068\u6307\u6458\u3055\u308c\u305f\u3088\u3046\u306a\u611f\u3058\u306a\u306e\u304b\u3001\u6df1\u523b\u3055\u306f\u3042\u308a\u307e\u305b\u3093\u3002 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