{"id":17917,"date":"2022-01-17T08:41:00","date_gmt":"2022-01-16T23:41:00","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=17917"},"modified":"2022-01-17T08:41:00","modified_gmt":"2022-01-16T23:41:00","slug":"post-17917","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=17917","title":{"rendered":"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3063\u3066\u52b9\u679c\u306f\u3069\u3046\uff1f"},"content":{"rendered":"<p>\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306b\u3064\u3044\u3066\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306f\u3001\u5404\u793e\u304b\u3089\u8ca9\u58f2\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u3001\u5148\u751f\u304c\u793a\u3055\u308c\u305f\u8840\u7cd6\u306a\u3069\u306e\u30c7\u30fc\u30bf\u3092\u898b\u3066\u3082\u7cd6\u8cea\u5236\u9650\u306b\u306f\u5168\u304f\u53ca\u3070\u306a\u3044\u3067\u3059\u306d\u3002<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u4e2d\u3067\u3082\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3001\u5225\u540d\u03b1\u30aa\u30ea\u30b4\u7cd6\u306f\u3001\u9762\u767d\u3044\u69cb\u9020\u3092\u3057\u3066\u3044\u3066\u8840\u7cd6\u3084\u4e2d\u6027\u8102\u80aa\u3001sdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308b\u3088\u3046\u3067\u3059\u3002<\/span><\/p>\n<p>\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3068\u3044\u3046\u3082\u306e\u3092\u3054\u5b58\u3058\u3067\u3057\u3087\u3046\u304b\uff1f\u79c1\u306f\u77e5\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u60c5\u5831\u3060\u3051\u3092\u8aad\u3081\u3070\u306a\u304b\u306a\u304b\u8208\u5473\u6df1\u3044\u7269\u8cea\u3067\u3059\u304c\u3001\u4e00\u65b9\u3044\u3064\u3082\u306e\u3088\u3046\u306b\u7709\u553e\u306e\u3088\u3046\u306a\u6c17\u3082\u3057\u307e\u3059\u3002<a href=\"http:\/\/www.cyclochem.com\/acd\/index.html\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u30b5\u30a4\u30c8<\/a>\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u3053\u3068\u3067\u306f\u3001\u8840\u7cd6\u5024\u4e0a\u6607\u6291\u5236\u52b9\u679c\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u6e1b\u52b9\u679c\u3001\u4e2d\u6027\u8102\u80aa\u5438\u53ce\u963b\u5bb3\u52b9\u679c\u3001\u98fd\u548c\u8102\u80aa\u9178\u306e\u9078\u629e\u7684\u6392\u6cc4\u306a\u3069\u69d8\u3005\u306a\u4f5c\u7528\u304c\u3042\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306f\u8840\u7cd6\u5024\u3084\u8102\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3088\u3046\u3067\u3059\u304c\u3001\u5b9f\u969b\u306b\u306f\u3069\u306e\u3088\u3046\u306a\u5831\u544a\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u3044\u304f\u3064\u304b\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>1\u65e56g\u306e\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u03b1-CD\uff09\u309212\u9031\u9593\u98f2\u3093\u3060\u5834\u5408\u306e\u7814\u7a76\u3067\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u5909\u5316\u304c\u3042\u308a\u307e\u3057\u305f\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27405337\/\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09<\/p>\n<div class=\"xtable\">\n<table class=\"rendered small default_table\" style=\"width: 87.1099%; height: 295px;\" frame=\"hsides\" rules=\"groups\">\n<thead>\n<tr>\n<th style=\"width: 265px;\">\u8102\u8cea\u3068\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea<\/th>\n<th style=\"width: 84px;\">\u30d7\u30e9\u30bb\u30dc<\/th>\n<th style=\"width: 84px;\">\u03b1-CD<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"width: 265px;\">\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08&lt;200 mg \/ dL\uff09<\/td>\n<td style=\"width: 84px;\">180\u00b14<\/td>\n<td style=\"width: 84px;\">180\u00b14<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">\u4e2d\u6027\u8102\u80aa\uff08&lt;150 mg \/ dL\uff09<\/td>\n<td style=\"width: 84px;\">97\u00b16<\/td>\n<td style=\"width: 84px;\">100\u00b16<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">LDL-C\uff08&lt;100 mg \/ dL\uff09<\/td>\n<td style=\"width: 84px;\">103\u00b13<\/td>\n<td style=\"width: 84px;\">103\u00b13<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">LDL-p\uff08&lt;1000 nmol \/ L\uff09<\/td>\n<td style=\"width: 84px;\">1038\u00b147<\/td>\n<td style=\"width: 84px;\">1005\u00b145<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">sLDL-p\uff08&lt;1317 nmol \/ L\uff09<\/td>\n<td style=\"width: 84px;\"><span style=\"color: #ff0000;\">405\u00b138<\/span><\/td>\n<td style=\"width: 84px;\"><span style=\"color: #ff0000;\">365\u00b135<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">HDL-C\uff08&lt;40 mg \/ dL\uff09<\/td>\n<td style=\"width: 84px;\">58\u00b12<\/td>\n<td style=\"width: 84px;\">60\u00b12<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 265px;\">HDL-p\uff0824\u201349 umol \/ L\uff09<\/td>\n<td style=\"width: 84px;\">35\u00b11<\/td>\n<td style=\"width: 84px;\">35\u00b11<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\u3067\u3042\u308bsdLDL\u306e\u7c92\u5b50\u6570\u306f\u304a\u3088\u305d10\uff05\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u4ed6\u306f\u5909\u5316\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4e2d\u6027\u8102\u80aa\u3082\u6e1b\u5c11\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<div class=\"xtable\">\n<table class=\"rendered small default_table\" style=\"width: 80.6957%; height: 261px;\" frame=\"hsides\" rules=\"groups\">\n<thead>\n<tr>\n<th style=\"width: 331px;\">\u7cd6\u4ee3\u8b1d<\/th>\n<th style=\"width: 85px;\">\u30d7\u30e9\u30bb\u30dc<\/th>\n<th style=\"width: 75px;\">\u03b1-CD<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"width: 331px;\">\u4f53\u91cd\uff08Kg\uff09<\/td>\n<td style=\"width: 85px;\">74.8\u00b11.9<\/td>\n<td style=\"width: 75px;\">74.7\u00b12<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 331px;\">\u8840\u7cd6\u5024\uff0874\u2013106 mg \/ dL\uff09<\/td>\n<td style=\"width: 85px;\"><span style=\"color: #ff0000;\">88\u00b10.9<\/span><\/td>\n<td style=\"width: 75px;\"><span style=\"color: #ff0000;\">87\u00b10.7<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 331px;\">\u30a4\u30f3\u30b9\u30ea\u30f3\uff082.6 \u2212 24.9 mcU \/ mL\uff09<\/td>\n<td style=\"width: 85px;\">7.1\u00b10.5<\/td>\n<td style=\"width: 75px;\">7.3\u00b10.6<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 331px;\">HbA1C\uff084.0 \u2212 6.0\uff05\uff09<\/td>\n<td style=\"width: 85px;\">5.3\u00b10.4<\/td>\n<td style=\"width: 75px;\">5.3\u00b10.4<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 331px;\">\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u6307\u6570\uff08\uff05\uff09<\/td>\n<td style=\"width: 85px;\"><span style=\"color: #ff0000;\">1.6\u00b10.1<\/span><\/td>\n<td style=\"width: 75px;\"><span style=\"color: #ff0000;\">1.4\u00b10.1<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 331px;\">HOMA-IR<\/td>\n<td style=\"width: 85px;\">1.6\u00b10.1<\/td>\n<td style=\"width: 75px;\">1.5\u00b10.1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u8840\u7cd6\u5024\u3082\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3082\u5fae\u5999\u306a\u5909\u5316\u3067\u3059\u3002<\/p>\n<p>\u03b1-CD\u306b\u95a2\u9023\u3059\u308b\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u03b1-CD\u306e\u7d048\uff05\u304c\u8efd\u5ea6\u306e\u80c3\u8178\u75c7\u72b6\u3092\u8a34\u3048\u305f\u306e\u306b\u5bfe\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u3067\u306f3\uff05\u3067\u3057\u305f\u3002\u3053\u306e\u7cfb\u7d71\u306e\u85ac\u3084\u30b5\u30d7\u30ea\u306f\u3069\u3046\u3057\u3066\u3082\u80c3\u8178\u75c7\u72b6\uff08\u8179\u75db\u3001\u8179\u90e8\u81a8\u6e80\u611f\u306a\u3069\uff09\u304c\u591a\u304f\u306a\u308b\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u6b21\u306e\u7814\u7a76\u3067\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16373993\/\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09<\/p>\n<p>0\u30012\u30015\u3001\u307e\u305f\u306f10g\u306e\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3092\u6dfb\u52a0\u3057\u305f50g\u306e\u6d88\u5316\u6027\u70ad\u6c34\u5316\u7269\u3092\u542b\u3080\u767d\u7c73\u3092\u6442\u53d6\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17929\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17929\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?fit=897%2C1243&amp;ssl=1\" data-orig-size=\"897,1243\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f31\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?fit=216%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?fit=640%2C887&amp;ssl=1\" class=\"alignnone size-full wp-image-17929\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?resize=640%2C887\" alt=\"\" width=\"640\" height=\"887\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?w=897&amp;ssl=1 897w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?resize=216%2C300&amp;ssl=1 216w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?resize=739%2C1024&amp;ssl=1 739w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?resize=768%2C1064&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/7daeca5b3c12a7d2fcc48beed8dd6c2d.png?resize=320%2C443&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u8840\u7cd6\u5024\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u306e\u63a8\u79fb\u3067\u3059\u3002\u78ba\u304b\u306b\u98df\u5f8c\u8840\u7cd6\u5024\u306f\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u91cf\u304c\u591a\u304f\u306a\u308b\u306b\u3064\u308c\u3066\u3001\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u3082\u540c\u69d8\u306b\u3084\u3084\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u3082\u898b\u3048\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17928\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17928\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?fit=1505%2C516&amp;ssl=1\" data-orig-size=\"1505,516\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f32\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?fit=300%2C103&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?fit=640%2C219&amp;ssl=1\" class=\"alignnone size-full wp-image-17928\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?resize=640%2C219\" alt=\"\" width=\"640\" height=\"219\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?w=1505&amp;ssl=1 1505w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?resize=300%2C103&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?resize=1024%2C351&amp;ssl=1 1024w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?resize=768%2C263&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?resize=320%2C110&amp;ssl=1 320w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/367a06d04b47e0e55bacfa78349fdab4.png?w=1280 1280w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21554816\/\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09<\/p>\n<p>10g\u306e\u03b1-\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3068100g\u306e\u7802\u7cd6\u3092\u6df7\u305c\u305f\u30c9\u30ea\u30f3\u30af\u3092\u98f2\u307f\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e8a1aa0d331b8d1ce25029109196200.gif\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17930\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17930\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e8a1aa0d331b8d1ce25029109196200.gif?fit=1380%2C432&amp;ssl=1\" data-orig-size=\"1380,432\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3urn_cambridge.org_id_binary_20160920224400866-0743_S0007114511000444_S0007114511000444_fig2g\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e8a1aa0d331b8d1ce25029109196200.gif?fit=300%2C94&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e8a1aa0d331b8d1ce25029109196200.gif?fit=640%2C201&amp;ssl=1\" class=\"alignnone size-full wp-image-17930\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e8a1aa0d331b8d1ce25029109196200.gif?resize=640%2C200\" alt=\"\" width=\"640\" height=\"200\" 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rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17935\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17935\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?fit=768%2C423&amp;ssl=1\" data-orig-size=\"768,423\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3foods-09-00062-g001\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?fit=300%2C165&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?fit=640%2C353&amp;ssl=1\" class=\"alignnone size-full wp-image-17935\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?resize=640%2C353\" alt=\"\" width=\"640\" height=\"353\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?w=768&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?resize=300%2C165&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/6a5cf8697f46f99e4aa9fb356af52d15.jpg?resize=320%2C176&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17934\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17934\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?fit=769%2C421&amp;ssl=1\" data-orig-size=\"769,421\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3foods-09-00062-g002\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?fit=300%2C164&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?fit=640%2C350&amp;ssl=1\" class=\"alignnone size-full wp-image-17934\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?resize=640%2C350\" alt=\"\" width=\"640\" height=\"350\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?w=769&amp;ssl=1 769w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?resize=300%2C164&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/9e3580161e9f0e339a75ac21a2b46c6e.jpg?resize=320%2C175&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23806736\/\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/4bd2ad1bdbde5362575f8b209a874ac8.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"17942\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17942\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/4bd2ad1bdbde5362575f8b209a874ac8.png?fit=698%2C437&amp;ssl=1\" data-orig-size=\"698,437\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u30bd\u30fc\u30bb\u30fc\u30b8\u30de\u30d5\u30a3\u30f3\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/4bd2ad1bdbde5362575f8b209a874ac8.png?fit=300%2C188&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/4bd2ad1bdbde5362575f8b209a874ac8.png?fit=640%2C401&amp;ssl=1\" class=\"alignnone size-full wp-image-17942\" 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decoding=\"async\" data-attachment-id=\"17937\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=17937\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/5c5bca68ee5e26da11a9ed69dd322e6b-e1642165094648.jpeg?fit=259%2C181&amp;ssl=1\" data-orig-size=\"259,181\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u03b1\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3046\u3093\u3053m_nxy135fig4\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/5c5bca68ee5e26da11a9ed69dd322e6b-e1642165094648.jpeg?fit=300%2C211&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/5c5bca68ee5e26da11a9ed69dd322e6b-e1642165094648.jpeg?fit=259%2C181&amp;ssl=1\" class=\"alignnone wp-image-17937 size-full\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/01\/5c5bca68ee5e26da11a9ed69dd322e6b-e1642165094648.jpeg?resize=259%2C181\" alt=\"\" width=\"259\" height=\"181\" 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