{"id":18135,"date":"2022-02-07T09:02:40","date_gmt":"2022-02-07T00:02:40","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=18135"},"modified":"2022-02-07T09:02:40","modified_gmt":"2022-02-07T00:02:40","slug":"post-18135","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=18135","title":{"rendered":"\u30d7\u30ed\u30c6\u30a4\u30f3\u6442\u53d6\u306f\u614e\u91cd\u306b"},"content":{"rendered":"

\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u5f71\u97ff\u3067\u69d8\u3005\u306a\u7523\u696d\u3001\u4f01\u696d\u304c\u6253\u6483\u3092\u53d7\u3051\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5e74\u672b\u9803\u306b\u725b\u4e73\u306e\u6d88\u8cbb\u4f4e\u8ff7\u3067\u5728\u5eab\u304c\u5897\u52a0\u3057\u7834\u68c4\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3088\u3046\u306a\u4e8b\u614b\u306b\u76f4\u9762\u3057\u305f\u6642\u3001\u306a\u305c\u304b\u81ea\u6cbb\u4f53\u3084\u56fd\u306a\u3069\u3082\u725b\u4e73\u6d88\u8cbb\u62e1\u5927\u3092\u8a34\u3048\u3066\u3044\u307e\u3057\u305f\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u3069\u3053\u304b\u3068\u3069\u3053\u304b\u306e\u88cf\u5074\u306e\u3064\u306a\u304c\u308a\u304c\u5f37\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u3044\u307e\u3060\u306b\u5c0f\u5b66\u6821\u306a\u3069\u306e\u7d66\u98df\u3067\u725b\u4e73\u304c\u51fa\u3066\u3044\u308b\u3053\u3068\u306f\u4e0d\u601d\u8b70\u3067\u3059\u3002\u3053\u306e\u6642\u4ee3\u306b\u306a\u3063\u3066\u3082\u725b\u4e73\u306f\u5065\u5eb7\u7684\u306a\u6804\u990a\u6e80\u70b9\u306a\u98f2\u307f\u7269\u3068\u3044\u3046\u8a8d\u8b58\u306a\u3093\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u307e\u305f\u3001\u65e5\u672c\u3067\u306f\u8fd1\u5e74\u30d7\u30ed\u30c6\u30a4\u30f3\u30d6\u30fc\u30e0\u304c\u8d77\u304d\u3066\u3044\u307e\u3059\u3002\u30de\u30b9\u30b3\u30df\u3082\u30cd\u30c3\u30c8\u4e0a\u3067\u3082\u30d7\u30ed\u30c6\u30a4\u30f3\u306b\u95a2\u3059\u308b\u8a71\u984c\u304c\u975e\u5e38\u306b\u591a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u9ad8\u30bf\u30f3\u30d1\u30af\u3092\u8b33\u3046\u5546\u54c1\u3082\u3082\u306e\u3059\u3054\u3044\u6570\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3082\u3061\u308d\u3093\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3001\u5fc5\u9808\u306e\u6804\u990a\u7d20\u3067\u3059\u304c\u3001\u3042\u307e\u308a\u306b\u3082\u30bf\u30f3\u30d1\u30af\u8cea\u4e0d\u8db3\u3068\u601d\u308f\u3055\u308c\u904e\u304e\u3066\u3044\u308b\u611f\u3058\u3082\u53d7\u3051\u307e\u3059\u3002<\/p>\n

\u69d8\u3005\u306a\u60c5\u5831\u3092\u3082\u3068\u306b\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u3092\u98f2\u3093\u3067\u3044\u308b\u4eba\u3082\u591a\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u306e\u5b89\u5168\u6027\u304c\u78ba\u304b\u3081\u3089\u308c\u308b\u524d\u306b\u5e02\u5834\u3067\u306f\u30d7\u30ed\u30c6\u30a4\u30f3\u5546\u54c1\u304c\u3042\u3075\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6442\u308a\u904e\u304e\u304c\u814e\u81d3\u306b\u60aa\u3044\u3068\u3044\u3046\u306e\u306f\u79c1\u306f\u5426\u5b9a\u7684\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u5225\u306e\u9762\u3067\u306e\u554f\u984c\u3092\u61f8\u5ff5\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u306f\u69d8\u3005\u306a\u6709\u76ca\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u591a\u304f\u306f\u8840\u7cd6\u5024\u3092\u4e0b\u3052\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3001IGF-1\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50\uff09\u5206\u6ccc\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u305d\u308c\u306b\u4f34\u3046mTOR\u6d3b\u6027\u5316\u3082\u6291\u5236\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u8d77\u3053\u3063\u3066\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u5b50\u4f9b\u306e\u3053\u308d\u306f\u4f53\u306e\u6210\u9577\u306b\u91cd\u8981\u306a\u3082\u306e\u304c\u3001\u5927\u4eba\u306b\u3068\u3063\u3066\u306f\u6210\u9577\u306f\u8001\u5316\u3068\u304c\u3093\u5316\u3092\u62db\u304f\u53ef\u80fd\u6027\u304c\u3042\u308b\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u90e8\u5206\u3092\u7cd6\u8cea\u5236\u9650\u3067\u306f\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n

\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f3\u306f\u3001\u725b\u4e73\u7531\u6765\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002\u725b\u4e73\u3082\u3082\u3061\u308d\u3093\u3067\u3059\u304c\u725b\u4e73\u7531\u6765\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3001IGF-1\u5206\u6ccc\u5897\u52a0\u3092\u3082\u305f\u3089\u3057\u3001mTOR\u306e\u6d3b\u6027\u5316\u3092\u62db\u304d\u307e\u3059\u3002\u7cd6\u8cea\u3092\u542b\u3093\u3060\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f3\u306f\u7cd6\u8cea\u3060\u3051\u3088\u308a\u30821.6\u500d\u3082\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5206\u6ccc\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n

\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u725b\u4e73\u3067\u5272\u308c\u3070\u3055\u3089\u306b\u305d\u306e\u3088\u3046\u306a\u4f5c\u7528\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u4eba\u985e\u306f\u3053\u308c\u307e\u3067\u6db2\u4f53\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6442\u3063\u3066\u304d\u305f\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u308c\u304c\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u6c34\u3084\u725b\u4e73\u306b\u6eb6\u304b\u3057\u3066\u98f2\u3080\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u304c\u51fa\u56de\u3063\u305f\u3053\u3068\u3067\u3001\u975e\u5e38\u306b\u5438\u53ce\u306e\u826f\u3044\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u4eba\u9593\u306f\u624b\u306b\u3057\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u5438\u53ce\u304c\u826f\u3051\u308c\u3070\u8840\u4e2d\u6fc3\u5ea6\u306e\u4e0a\u6607\u3082\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002\u7cd6\u8cea\u3082\u3086\u3063\u304f\u308a\u3068\u6442\u53d6\u3059\u308c\u3070\u5438\u53ce\u3082\u3086\u3063\u304f\u308a\u3067\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3082\u7de9\u3084\u304b\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u308c\u3068\u540c\u69d8\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u3082\u8089\u306a\u3069\u304b\u3089\u6442\u53d6\u3059\u308c\u3070\u3086\u3063\u304f\u308a\u5438\u53ce\u3055\u308c\u307e\u3059\u304c\u3001\u6db2\u4f53\u72b6\u3067\u306f\u975e\u5e38\u306b\u7d20\u65e9\u304f\u4f53\u5185\u306b\u5165\u308a\u3001\u305d\u306e\u5206\u4f53\u306e\u53cd\u5fdc\u3082\u6025\u6fc0\u306b\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u306f\u8840\u7cd6\u5024\u3092\u3042\u307e\u308a\u4e0a\u3052\u307e\u305b\u3093\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u5897\u52a0\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n

\u7537\u6027\u3082\u3082\u3061\u308d\u3093\u305d\u3046\u3067\u3059\u304c\u3001AYA\u4e16\u4ee3\u306e\u82e5\u3044\u5973\u6027\u306e\u9593\u3067\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u304c\u6d41\u884c\u3057\u3066\u3044\u308b\u306e\u306f\u975e\u5e38\u306b\u6050\u308d\u3057\u3044\u3053\u3068\u306b\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u3082IGF-1\u3082\u304c\u3093\u3068\u7d50\u3073\u3064\u3044\u3066\u3044\u308b\u304b\u3089\u3067\u3059\u3002\u62d9\u8457\u300c\u80a5\u6e80\u30fb\u7cd6\u5c3f\u75c5\u306e\u4eba\u306f\u306a\u305c\u65b0\u578b\u30b3\u30ed\u30ca\u306b\u5f31\u3044\u306e\u304b \u300c\u7cd6\u8cea\u904e\u5270\u300d\u75c7\u5019\u7fa4II<\/a>\u00a0\u300d\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001AYA\u4e16\u4ee3\u306e\u304c\u3093\u306e\u5897\u52a0\u306f\u8457\u3057\u3044\u3067\u3059\u300215\uff5e39\u6b73\u306e\u601d\u6625\u671f\u30fb\u82e5\u5e74\uff08AYA\uff09\u4e16\u4ee3\u306e\u304c\u3093\u60a3\u8005\u3067\u3001\u591a\u304f\u306f\u5973\u6027\u304c\u5360\u3081\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002AYA\u4e16\u4ee3\u306e\u4e2d\u306720\uff5e39\u6b73\u306e\u60a3\u8005\u306e\u7d048\u5272\u3092\u5973\u6027\u304c\u5360\u3081\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u4e73\u304c\u3093\u3084\u5b50\u5bae\u9838\u304c\u3093\u306e\u5897\u52a0\u304c\u5927\u304d\u306a\u539f\u56e0\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u4e73\u304c\u3093\u3067\u7cd6\u8cea\u5236\u9650\u3092\u3057\u305f\u65b9\u304c\u826f\u3044\u7406\u7531<\/a>\u300d\u3067\u793a\u3057\u305f\u3088\u3046\u306b\u3001\u4e73\u304c\u3093\u7d30\u80de\u306b\u306f\u7d046\u500d\u3082\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u53d7\u5bb9\u4f53\u304c\u3042\u308a\u307e\u3059\u3002IGF-1\u304c\u9ad8\u3044\u30688\u500d\u4ee5\u4e0a\u3001\u5b50\u5bae\u9838\u304c\u3093\u306e\u524d\u304c\u3093\u75c5\u5909\u306b\u306a\u308a\u3084\u3059\u3044\u306e\u3067\u3059\u3002<\/p>\n

\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f3\u306b\u8c4a\u5bcc\u306a\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u306f\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3001IGF-1\u306e\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\u3001\u30ed\u30a4\u30b7\u30f3\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002\u30b0\u30eb\u30bf\u30df\u30f3\u3082mTOR\u3092\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002\u725b\u4e73\u304a\u3088\u3073\u725b\u4e73\u7531\u6765\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u306f\u4ed6\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3082\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305b\u3063\u304b\u304f\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3082\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u9078\u629e\u3092\u9593\u9055\u3048\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3068\u540c\u69d8\u306a\u30ea\u30b9\u30af\u5897\u52a0\u3092\u8d77\u3053\u3057\u3066\u3057\u307e\u3046\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u725b\u4e73\u306f\u725b\u306e\u8d64\u3061\u3083\u3093\u3092\u5927\u304d\u304f\u3059\u308b\u305f\u3081\u306e\u304a\u4e73\u3067\u3059\u3002\u725b\u306f\u4eba\u9593\u3088\u308a\u4f55\u500d\u3082\u901f\u304f\u6210\u9577\u3057\u307e\u3059\u3002<\/p>\n

\u725b\u4e73\u6442\u53d6\u91cf\u304c\u591a\u3044\u3068\u3001\u521d\u6f6e\u304c\u65e9\u304f\u306a\u308b\u3068\u3082\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u30cb\u30ad\u30d3\u3082IGF-1\u3001\uff4dTOR\u306e\u6d3b\u6027\u5316\u304c\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u30dc\u30c7\u30a3\u30fc\u30d3\u30eb\u306e\u305f\u3081\u306b\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u59cb\u3081\u305f\u82e5\u3044\u7537\u6027\u304c\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u98f2\u307f\u59cb\u3081\u3066\u304b\u3089\u4f53\u5e79\u306b\u30cb\u767a\u751f\u3057\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u4e2d\u6b62\u3067\u6539\u5584\u3057\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\uff08\u3082\u3061\u308d\u3093\u3001\u3053\u306e\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u306b\u306f\u5927\u91cf\u306e\u7cd6\u8cea\u304c\u5165\u3063\u3066\u3044\u305f\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002\uff09<\/p>\n

\u3064\u307e\u308a\u3001\u521d\u6f6e\u304c\u65e9\u304f\u3001\u8eab\u9577\u304c\u6bd4\u8f03\u7684\u9ad8\u304f\u3001\u30cb\u30ad\u30d3\u304c\u591a\u3044\u307e\u305f\u306f\u4ee5\u524d\u591a\u304b\u3063\u305f\u5973\u6027\u306f\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u725b\u4e73\u7531\u6765\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u3082\u53cd\u5fdc\u3057\u3084\u3059\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u8840\u7cd6\u5024\u306e\u63a8\u79fb\u3060\u3051\u3092\u898b\u308c\u3070\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u3092\u98f2\u3093\u3067\u3082\u307b\u3068\u3093\u3069\u5909\u5316\u3057\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u898b\u3048\u306a\u3044\u88cf\u5074\u3067\u306f\u3001\u5065\u5eb7\u306b\u6709\u5bb3\u306b\u306a\u308a\u3046\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u52d5\u3044\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u7cd6\u8cea\u5236\u9650\u3067\u306f\u3001\u300c\u7cd6\u8cea\uff1d\u60aa\u7389\u300d\u3068\u3044\u3046\u56f3\u5f0f\u3067\u3059\u304c\u3001\u305d\u306e\u6d41\u308c\u3067\u300c\u30bf\u30f3\u30d1\u30af\u8cea\uff1d\u5584\u7389\u300d\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5168\u3066\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u540c\u3058\u3088\u3046\u306b\u306f\u3068\u3089\u3048\u3089\u308c\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u77ed\u671f\u7684\u306b\u898b\u308c\u3070\u672c\u5f53\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u4e0d\u8db3\u306e\u4eba\u3067\u306f\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u6442\u53d6\u306f\u4f53\u8abf\u306a\u3069\u306e\u6539\u5584\u3092\u8a8d\u3081\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u9577\u671f\u7684\u306b\u898b\u308c\u3070\u5b89\u5168\u6027\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u3057\u3001\u4f55\u304b\u3042\u3063\u3066\u3082\u56e0\u679c\u95a2\u4fc2\u306f\u4e0d\u660e\u3068\u3055\u308c\u308b\u3067\u3057\u3087\u3046\u3002\uff08\u306a\u3093\u304b\u3069\u3053\u304b\u306e\u30ef\u30af\u30c1\u30f3\u306b\u4f3c\u3066\u3044\u307e\u3059\u306d\uff1f\uff09\u304c\u3093\u3078\u306e\u5f71\u97ff\u306f\u304b\u306a\u308a\u7d4c\u3063\u3066\u304b\u3089\u3057\u304b\u73fe\u308c\u307e\u305b\u3093\u3002\u30d7\u30ed\u30c6\u30a4\u30f3\u306b\u3088\u308b\u4ee3\u8b1d\u3078\u306e\u5f71\u97ff\u3092\u8003\u3048\u308c\u3070\u3001\u5341\u5206\u306a\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002BUN20\u4ee5\u4e0a\u3092\u76ee\u6307\u3057\u3066\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u6442\u53d6\u3057\u7d9a\u3051\u308b\u306e\u3082\u554f\u984c\u3067\u3059\u3002\uff08\u300c\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306b\u5bfe\u3059\u308b\u6839\u62e0\u7121\u304d\u7406\u60f3\u5024\u3000\u305d\u306e1<\/a>\u300d\u306a\u3069\u53c2\u7167\uff09<\/p>\n

\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306f\u91cd\u8981\u3067\u3059\u3002\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u306f\u305d\u306e\u624b\u8efd\u3055\u3067\u4eba\u6c17\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u3057\u304b\u3057\u3001\u672c\u5f53\u306b\u5b89\u5168\u304b\u3069\u3046\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f320g\u306f\u725b\u4e73\u30b3\u30c3\u30d7\u7d043\u676f\u5206\uff08600ml\uff09\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u542b\u3093\u3067\u3044\u307e\u3059\u3002\u6bce\u65e5\u306e\u6442\u53d6\u306f\u304a\u52e7\u3081\u3057\u307e\u305b\u3093\u3002\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3084\u7cd6\u8cea\u904e\u5270\uff0b\u30d7\u30ed\u30c6\u30a4\u30f3\u3088\u308a\u306f\u30ea\u30b9\u30af\u306f\u5c11\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u306b\u95a2\u9023\u3059\u308b\u4f01\u696d\u306e\u6226\u7565\u3084\u4e00\u90e8\u306e\u5c02\u9580\u5bb6\u306b\u60d1\u308f\u3055\u308c\u305a\u3001\u614e\u91cd\u306b\u9078\u629e\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

 <\/p>\n

\u300cLifetime Impact of Cow’s Milk on Overactivation of mTORC1: From Fetal to Childhood Overgrowth, Acne, Diabetes, Cancers, and Neurodegeneration\u300d<\/span><\/p>\n

\u300cmTORC1\u306e\u904e\u5270\u6d3b\u6027\u5316\u306b\u5bfe\u3059\u308b\u725b\u4e73\u306e\u751f\u6daf\u306e\u5f71\u97ff\uff1a\u80ce\u5150\u304b\u3089\u5c0f\u5150\u671f\u306e\u7570\u5e38\u6210\u9577\u304b\u3089\u3001\u306b\u304d\u3073\u3001\u7cd6\u5c3f\u75c5\u3001\u304c\u3093\u3001\u304a\u3088\u3073\u795e\u7d4c\u5909\u6027\u307e\u3067\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u5f71\u97ff\u3067\u69d8\u3005\u306a\u7523\u696d\u3001\u4f01\u696d\u304c\u6253\u6483\u3092\u53d7\u3051\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5e74\u672b\u9803\u306b\u725b\u4e73\u306e\u6d88\u8cbb\u4f4e\u8ff7\u3067\u5728\u5eab\u304c\u5897\u52a0\u3057\u7834\u68c4\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3088\u3046\u306a\u4e8b\u614b\u306b\u76f4\u9762\u3057\u305f\u6642\u3001\u306a\u305c\u304b\u81ea\u6cbb\u4f53\u3084\u56fd\u306a\u3069\u3082\u725b\u4e73\u6d88\u8cbb\u62e1\u5927\u3092\u8a34\u3048\u3066\u3044\u307e\u3057\u305f\u3002\uff08\u3053\u3053\u53c2\u7167\uff09\u3069<\/p>\n","protected":false},"author":1,"featured_media":18136,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,150,153,171],"tags":[80,19,58],"class_list":["post-18135","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-diabetes","category-cancer","category-171","tag-80","tag-toushitsuseigen","tag-cancer","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/02\/23260002_s.jpg?fit=640%2C427&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-4Iv","jetpack-related-posts":[{"id":15722,"url":"https:\/\/promea2014.com\/blog\/?p=15722","url_meta":{"origin":18135,"position":0},"title":"\u725b\u4e73\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5927\u304d\u304f\u5897\u52a0\u3055\u305b\u308b","author":"Dr.Shimizu","date":"2021\u5e744\u67089\u65e5","format":false,"excerpt":"\u5c0f\u3055\u3044\u9803\u3001\u80cc\u304c\u9ad8\u304f\u306a\u308a\u305f\u304f\u3066\u725b\u4e73\u3092\u305f\u304f\u3055\u3093\u98f2\u3093\u3067\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u7d50\u679c\u7684\u306b\u306f\u4eca\u306f\u3061\u3093\u3061\u304f\u308a\u3093\u306e\u304a\u3058\u3055\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/04\/4609034_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/04\/4609034_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/04\/4609034_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":16614,"url":"https:\/\/promea2014.com\/blog\/?p=16614","url_meta":{"origin":18135,"position":1},"title":"\u725b\u4e73\u3067\u4e73\u304c\u3093\u30ea\u30b9\u30af\u306e\u4e0a\u6607\uff1f\u5973\u6027\u306f\u30d7\u30ed\u30c6\u30a4\u30f3\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u304b\u3082\u3057\u308c\u306a\u3044","author":"Dr.Shimizu","date":"2021\u5e748\u670813\u65e5","format":false,"excerpt":"\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u725b\u4e73\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5927\u304d\u304f\u5897\u52a0\u3055\u305b\u308b\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u725b\u4e73\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u2026","rel":"","context":"\u304c\u3093","block_context":{"text":"\u304c\u3093","link":"https:\/\/promea2014.com\/blog\/?cat=153"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/4667551_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/4667551_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/08\/4667551_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":9265,"url":"https:\/\/promea2014.com\/blog\/?p=9265","url_meta":{"origin":18135,"position":2},"title":"\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306b\u3088\u308b\u6709\u5bb3\u6027\u306f\uff1f\u3000\u305d\u306e2","author":"Dr.Shimizu","date":"2019\u5e748\u67086\u65e5","format":false,"excerpt":"\u4eba\u9593\u3060\u3051\u3067\u306a\u304f\u3001\u751f\u7269\u306b\u306f\u5bff\u547d\u304c\u3042\u308a\u307e\u3059\u3002\u5bff\u547d\u3092\u5168\u3046\u3059\u308b\u524d\u306b\u8001\u5316\u3068\u3044\u3046\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002\u8001\u5316\u306e\u524d\u306b\u306f\u6210\u9577\u2026","rel":"","context":"\u7cd6\u5c3f\u75c5","block_context":{"text":"\u7cd6\u5c3f\u75c5","link":"https:\/\/promea2014.com\/blog\/?cat=150"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/ca13efb533ab46621c6f6f145138942f_s.jpg?fit=640%2C597&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/ca13efb533ab46621c6f6f145138942f_s.jpg?fit=640%2C597&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/ca13efb533ab46621c6f6f145138942f_s.jpg?fit=640%2C597&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":17155,"url":"https:\/\/promea2014.com\/blog\/?p=17155","url_meta":{"origin":18135,"position":3},"title":"\u7b4b\u8089\u3092\u5897\u3084\u3059\u306e\u306b\u7cd6\u8cea\u306f\u5fc5\u8981\u306a\u3044","author":"Dr.Shimizu","date":"2021\u5e7410\u670827\u65e5","format":false,"excerpt":"\u7b4b\u8089\u3092\u5897\u3084\u3059\u306e\u306b\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u3060\u304b\u3089\u30bf\u30f3\u30d1\u30af\u8cea\u3060\u3051\u3067\u306a\u304f\u7cd6\u8cea\uff08\u70ad\u6c34\u5316\u7269\uff09\u306e\u6442\u53d6\u3082\u540c\u6642\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/22153031_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/22153031_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/10\/22153031_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":9151,"url":"https:\/\/promea2014.com\/blog\/?p=9151","url_meta":{"origin":18135,"position":4},"title":"\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306b\u3088\u308b\u6709\u5bb3\u6027\u306f\uff1f\u3000\u305d\u306e1","author":"Dr.Shimizu","date":"2019\u5e748\u67085\u65e5","format":false,"excerpt":"\u826f\u3044\u3053\u3068\u305a\u304f\u3081\u306e\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u7cd6\u5c3f\u75c5\u306e\u4eba\u3067\u306f\u5c11\u3057\u6ce8\u610f\u304c\u5fc5\u8981\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002 \u300c\u30bf\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/07\/5b8efb67f6697b84a8fc1d9f5f5035d6_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/07\/5b8efb67f6697b84a8fc1d9f5f5035d6_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/07\/5b8efb67f6697b84a8fc1d9f5f5035d6_s.jpg?fit=640%2C480&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":9288,"url":"https:\/\/promea2014.com\/blog\/?p=9288","url_meta":{"origin":18135,"position":5},"title":"\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306b\u3088\u308b\u6709\u5bb3\u6027\u306f\uff1f\u3000\u305d\u306e3\u3000\u30a2\u30b9\u30ea\u30fc\u30c8","author":"Dr.Shimizu","date":"2019\u5e748\u67088\u65e5","format":false,"excerpt":"\u524d\u56de\u306e\u8a18\u4e8b\u300c\u305d\u306e2\u300d\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u3068mTOR\u306e\u6d3b\u6027\u5316\u306b\u3064\u3044\u3066\u66f8\u304d\u307e\u3057\u305f\u3002\u305d\u306e\u6700\u5f8c\u306e\u65b9\u3067\u6700\u8fd1\u82e5\u3044\u30a2\u2026","rel":"","context":"\u304c\u3093","block_context":{"text":"\u304c\u3093","link":"https:\/\/promea2014.com\/blog\/?cat=153"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1da4c6f27b19a4ae1fe2f42e30058265_s.jpg?fit=640%2C473&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1da4c6f27b19a4ae1fe2f42e30058265_s.jpg?fit=640%2C473&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1da4c6f27b19a4ae1fe2f42e30058265_s.jpg?fit=640%2C473&ssl=1&resize=525%2C300 1.5x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18135"}],"version-history":[{"count":5,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18135\/revisions"}],"predecessor-version":[{"id":18143,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18135\/revisions\/18143"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/media\/18136"}],"wp:attachment":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}