{"id":18157,"date":"2022-02-17T08:39:31","date_gmt":"2022-02-16T23:39:31","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=18157"},"modified":"2022-02-17T08:39:31","modified_gmt":"2022-02-16T23:39:31","slug":"post-18157","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=18157","title":{"rendered":"\u4e2d\u5e74\u671f\u306b\u3044\u304f\u3064\u3082\u306e\u6162\u6027\u75be\u60a3\u304c\u3042\u308b\u3068\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b"},"content":{"rendered":"

\u591a\u304f\u306e\u75be\u60a3\u3001\u7279\u306b\u6162\u6027\u75be\u60a3\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3082\u306e\u306f\u3001\u307b\u3068\u3093\u3069\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u3088\u308b\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u6700\u521d\u306b\u51fa\u305f\u75c7\u72b6\u3001\u75be\u60a3\u3092\u653e\u7f6e\u3057\u3066\u3057\u307e\u3046\u3068\u305d\u306e\u5f8c\u3069\u3093\u3069\u3093\u69d8\u3005\u306a\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306b\u8972\u308f\u308c\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u300155\u6b73\uff5e70\u6b73\u306e\u591a\u75be\u60a3\uff082\u3064\u4ee5\u4e0a\u306e\u6162\u6027\u75be\u60a3\uff09\u7f79\u60a3\u306e\u6709\u75c5\u7387\u3068\u305d\u306e\u5f8c\u306e\u8a8d\u77e5\u75c7\u767a\u75c7\u306e\u30ea\u30b9\u30af\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u5bfe\u8c61\u306f\u30ed\u30f3\u30c9\u30f3\u3067\u52e4\u52d9\u3057\u3066\u3044\u308b35\uff5e55\u6b73\u306e\u516c\u52d9\u54e11\u4e0795\u4eba\uff08\u7537\u60276,895\u4eba\u3001\u5973\u60273,413\u4eba\uff09\u3067\u3059\u3002<\/p>\n

\u591a\u75be\u60a3\u7f79\u60a3\u306f\u300113\u75be\u60a3\uff08\u51a0\u52d5\u8108\u75be\u60a3\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u4e0d\u5168\u3001\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u5727\u3001\u304c\u3093\u3001\u6162\u6027\u814e\u75be\u60a3\u3001COPD\u3001\u809d\u75be\u60a3\u3001\u3046\u3064\u75c5\u3001\u7cbe\u795e\u75be\u60a3\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3001\u95a2\u7bc0\u708e\uff0f\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff09\u306e\u3046\u30612\u75be\u60a3\u4ee5\u4e0a\u3092\u6709\u3059\u308b\u5834\u5408\u3068\u5b9a\u7fa9\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u8ffd\u8de1\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f31.7\u5e74\u3067\u3059\u3002<\/p>\n

\u591a\u75be\u60a3\u7f79\u60a3\u306e\u7f79\u60a3\u7387\u306f55\u6b73\u6642\u30676.6\uff05\u300170\u6b73\u6642\u306731.7\uff05\u3067\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u305d\u308c\u305e\u308c\u306e\u5e74\u9f62\u3067\u306e\u7f79\u60a3\u7387\u3067\u3059\u3002\u75be\u60a3\u306e\u6570\u306b\u3088\u3063\u3066\u8272\u5206\u3051\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5e74\u9f62\u3068\u3068\u3082\u306b\u591a\u75be\u60a3\u7f79\u60a3\u306f\u5f53\u7136\u591a\u304f\u306a\u3063\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n

\n
<\/div>\n<\/div>\n\n\n\n\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u6162\u6027\u75be\u60a3<\/th>\n55\u6b73<\/th>\n60\u5e74<\/th>\n65\u6b73<\/th>\n70\u5e74<\/th>\n\u5168\u4f53<\/th>\n<\/tr>\n<\/thead>\n
\u51a0\u52d5\u8108\u6027\u5fc3\u81d3\u75c5<\/td>\n1.35\uff080.94\u301c1.95\uff09<\/td>\n1.46\uff081.11\u304b\u30891.92\uff09<\/span><\/td>\n1.31\uff081.03\u301c1.66\uff09<\/span><\/td>\n1.16\uff080.93\u301c1.45\uff09<\/td>\n1.25\uff081.04\u301c1.50\uff09<\/span><\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\nNA<\/td>\n3.55\uff081.46\u301c8.59\uff09<\/span><\/td>\n2.68\uff081.38\u301c5.20\uff09<\/span><\/td>\n1.62\uff080.89\u301c2.95\uff09<\/td>\n3.37\uff082.54\u304b\u30894.49\uff09<\/span><\/td>\n<\/tr>\n
\u5fc3\u4e0d\u5168<\/td>\nNA<\/td>\nNA<\/td>\n3.44\uff081.41\u304b\u30898.35\uff09<\/span><\/td>\n1.39\uff080.69\u301c2.81\uff09<\/td>\n2.49\uff081.88\u304b\u30893.32\uff09<\/span><\/td>\n<\/tr>\n
\u7cd6\u5c3f\u75c5<\/td>\n2.31\uff081.56\u304b\u30893.43\uff09<\/span><\/td>\n2.21\uff081.63\u301c2.99\uff09<\/span><\/td>\n1.98\uff081.54\u301c2.55\uff09<\/span><\/td>\n1.60\uff081.25\u301c2.05\uff09<\/span><\/td>\n1.63\uff081.35\u301c1.97\uff09<\/span><\/td>\n<\/tr>\n
\u9ad8\u8840\u5727<\/td>\n1.37\uff081.15\u304b\u30891.62\uff09<\/span><\/td>\n1.29\uff081.10\u304b\u30891.51\uff09<\/span><\/td>\n1.29\uff081.10\u301c1.52\uff09<\/span><\/td>\n1.31\uff081.10\u301c1.56\uff09<\/span><\/td>\n1.55\uff081.27\u301c1.88\uff09<\/span><\/td>\n<\/tr>\n
\u304c\u3093<\/td>\n0.97\uff080.50\u301c1.88\uff09<\/td>\n0.99\uff080.60\u301c1.64\uff09<\/td>\n0.69\uff080.44\u301c1.09\uff09<\/td>\n0.88\uff080.63\u301c1.24\uff09<\/td>\n1.06\uff080.85\u301c1.31\uff09<\/td>\n<\/tr>\n
\u6162\u6027\u814e\u81d3\u75c5<\/td>\nNA<\/td>\nNA<\/td>\nNA<\/td>\n5.18\uff082.29\u304b\u308911.70\uff09<\/span><\/td>\n2.98\uff082.22\u304b\u30893.99\uff09<\/span><\/td>\n<\/tr>\n
\u6162\u6027\u9589\u585e\u6027\u80ba\u75be\u60a3<\/td>\nNA<\/td>\nNA<\/td>\n3.64\uff081.49\u301c8.90\uff09<\/span><\/td>\n1.12\uff080.46\u301c2.72\uff09<\/td>\n2.20\uff081.63\u301c2.97\uff09<\/span><\/td>\n<\/tr>\n
\u809d\u75be\u60a3<\/td>\nNA<\/td>\nNA<\/td>\nNA<\/td>\nNA<\/td>\n1.89\uff081.11\u304b\u30893.21\uff09<\/span><\/td>\n<\/tr>\n
\u3046\u3064<\/td>\n1.42\uff080.94\u301c2.15\uff09<\/td>\n1.71\uff081.25\u301c2.35\uff09<\/span><\/td>\n1.79\uff081.36\u301c2.35\uff09<\/span><\/td>\n1.93\uff081.50\u301c2.50\uff09<\/span><\/td>\n2.95\uff082.44\u304b\u30893.57\uff09<\/span><\/td>\n<\/tr>\n
\u7cbe\u795e\u969c\u5bb3<\/td>\nNA<\/td>\n13.51\uff086.53\u304b\u308927.95\uff09<\/span><\/td>\n6.66\uff083.61\u304b\u308912.27\uff09<\/span><\/td>\n2.05\uff080.97\u301c4.35\uff09<\/td>\n5.73\uff084.48\u304b\u30897.34\uff09<\/span><\/td>\n<\/tr>\n
\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5<\/td>\nNA<\/td>\nNA<\/td>\n21.24\uff088.66\u304b\u308952.09\uff09<\/span><\/td>\n19.31\uff088.45\u304b\u308944.11\uff09<\/span><\/td>\n8.16\uff085.68\u304b\u308911.73\uff09<\/span><\/td>\n<\/tr>\n
\u95a2\u7bc0\u708e\/\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1<\/td>\nNA<\/td>\n1.66\uff080.68\u301c4.05\uff09<\/td>\n1.51\uff080.91\u304b\u30892.51\uff09<\/td>\n1.14\uff080.78\u301c1.67\uff09<\/td>\n1.49\uff081.22\u304b\u30891.81\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306f\u6162\u6027\u75be\u60a3\u306e\u305d\u308c\u305e\u308c\u500b\u5225\u3068\u305d\u306e\u5f8c\u306e\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u304c\u3093\u306f\u8a8d\u77e5\u75c7\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u308c\u4ee5\u5916\u306f\u95a2\u9023\u304c\u3042\u308a\u3001\u5e74\u9f62\u304c\u6bd4\u8f03\u7684\u82e5\u3044\u3068\u304d\u304b\u3089\u75be\u60a3\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u65b9\u304c\u5f53\u7136\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u306f\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\n
<\/div>\n<\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u591a\u767a\u6027\u75be\u60a3\u306e\u72b6\u614b<\/th>\n1000\u4eba\u5e74\u3042\u305f\u308a\u306e\u767a\u751f\u7387\u306e\u5dee\uff0895\uff05CI\uff09<\/th>\n\u30cf\u30b6\u30fc\u30c9\u6bd4\uff0895\uff05CI\uff09<\/th>\n<\/tr>\n
\u30e2\u30c7\u30eb1<\/th>\n\u30e2\u30c7\u30eb2<\/th>\n\u30e2\u30c7\u30eb3<\/th>\n<\/tr>\n<\/thead>\n
55\u6b73<\/strong><\/td>\n<\/tr>\n
\u6162\u6027\u75be\u60a30\u307e\u305f\u306f1\u3064<\/td>\n0<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n1.56\uff080.62\u301c2.77\uff09<\/td>\n2.51\uff081.87\u301c3.35\uff09<\/td>\n2.47\uff081.84\u301c3.30\uff09<\/td>\n2.44\uff081.82\u304b\u30893.26\uff09<\/span><\/td>\n<\/tr>\n
60\u6b73<\/strong><\/td>\n<\/tr>\n
\u6162\u6027\u75be\u60a30\u307e\u305f\u306f1\u3064<\/td>\n0<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
55\u301c60\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n0.60\uff08-0.38\u301c1.90\uff09<\/td>\n1.45\uff081.05\u301c1.99\uff09<\/td>\n1.40\uff081.02\u301c1.93\uff09<\/td>\n1.39\uff081.01\u301c1.91\uff09<\/span><\/td>\n<\/tr>\n
55\u6b73\u4ee5\u524d\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n2.42\uff081.09\u304b\u30894.12\uff09<\/td>\n2.57\uff081.91\u301c3.45\uff09<\/td>\n2.52\uff081.88\u301c3.39\uff09<\/td>\n2.46\uff081.83\u304b\u30893.31\uff09<\/span><\/td>\n<\/tr>\n
65\u6b73<\/strong><\/td>\n<\/tr>\n
\u6162\u6027\u75be\u60a30\u307e\u305f\u306f1\u3064<\/td>\n0<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
60\u301c65\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n1.85\uff080.64\u301c3.39\uff09<\/td>\n1.55\uff081.19\u304b\u30892.01\uff09<\/td>\n1.53\uff081.17\u301c1.99\uff09<\/td>\n1.51\uff081.16\u301c1.97\uff09<\/span><\/td>\n<\/tr>\n
55\u301c60\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n1.24\uff08-0.24\u304b\u30893.22\uff09<\/td>\n1.49\uff081.08\u301c2.07\uff09<\/td>\n1.44\uff081.03\u301c2.00\uff09<\/td>\n1.41\uff081.01\u301c1.96\uff09<\/span><\/td>\n<\/tr>\n
55\u6b73\u4ee5\u524d\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n3.86\uff081.80\u301c6.52\uff09<\/td>\n2.57\uff081.88\u301c3.50\uff09<\/td>\n2.52\uff081.85\u304b\u30893.44\uff09<\/td>\n2.46\uff081.80\u301c3.36\uff09<\/span><\/td>\n<\/tr>\n
70\u6b73<\/strong><\/td>\n<\/tr>\n
\u6162\u6027\u75be\u60a30\u307e\u305f\u306f1\u3064<\/td>\n0<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
65\u301c70\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n2.34\uff080.84\u304b\u30894.23\uff09<\/td>\n1.33\uff081.03\u301c1.72\uff09<\/td>\n1.32\uff081.02\u301c1.70\uff09<\/td>\n1.29\uff081.001\u301c1.67\uff09<\/span><\/td>\n<\/tr>\n
60\u301c65\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n2.32\uff080.41\u304b\u30894.82\uff09<\/td>\n1.45\uff081.07\u301c1.95\uff09<\/td>\n1.41\uff081.04\u301c1.89\uff09<\/td>\n1.38\uff081.02\u304b\u30891.86\uff09<\/span><\/td>\n<\/tr>\n
55\u301c60\u6b73\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n2.52\uff08-0.09\u301c6.10\uff09<\/td>\n1.50\uff081.04\u301c2.15\uff09<\/td>\n1.42\uff080.98\u301c2.04\uff09<\/td>\n1.36\uff080.94\u301c1.96\uff09<\/td>\n<\/tr>\n
55\u6b73\u4ee5\u524d\u306e\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n8.94\uff084.65\u304b\u308914.58\uff09<\/td>\n2.80\uff081.99\u301c3.94\uff09<\/td>\n2.71\uff081.92\u301c3.83\uff09<\/td>\n2.60\uff081.84\u301c3.67\uff09<\/span><\/td>\n<\/tr>\n
\u5168\u4f53<\/strong><\/td>\n<\/tr>\n
\u6162\u6027\u75be\u60a30\u307e\u305f\u306f1\u3064<\/td>\n0<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
\u591a\u75be\u60a3\u7f79\u60a3<\/td>\n1.59\uff081.51\u301c1.67\uff09<\/td>\n2.44\uff082.04\u301c2.91\uff09<\/td>\n2.44\uff082.04\u301c2.91\uff09<\/td>\n2.36\uff081.97\u301c2.81\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306f\u591a\u75be\u60a3\u7f79\u60a3\uff082\u3064\u4ee5\u4e0a\u306e\u6162\u6027\u72b6\u614b\uff09\u3068\u305d\u306e\u5f8c\u306e\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u6162\u6027\u75be\u60a3\u304c0\u307e\u305f\u306f1\u3064\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u300155\u6b73\u3067\u3059\u3067\u306b\u591a\u75be\u60a3\u7f79\u60a3\u3057\u3066\u3044\u308b\u3068\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306f2.44\u500d\u306b\u3082\u306a\u308a\u307e\u3059\u3002\u591a\u75be\u60a3\u7f79\u60a3\u306e\u767a\u75c7\u6642\u306e\u5e74\u9f62\u304c\u4f4e\u3044\u307b\u3069\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u308a\u300170\u6b73\u307e\u3067\u306f\u3001\u591a\u75be\u60a3\u7f79\u60a3\u306e\u767a\u75c7\u5e74\u9f62\u304c5\u6b73\u4e0b\u304c\u308b\u3054\u3068\u306b\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u304c18\uff05\u4e0a\u6607\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

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\"\"<\/a><\/p>\n

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1\u3064\u3067\u3082\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u75c7\u72b6\u3001\u75be\u60a3\u304c\u73fe\u308c\u305f\u5834\u5408\u3001\u305d\u306e\u6642\u306b\u6c17\u304c\u4ed8\u3044\u3066\u98df\u4e8b\u3092\u6539\u5584\u3059\u308c\u3070\u3001\u9006\u8ee2\u304c\u53ef\u80fd\u306a\u5834\u5408\u3082\u9ad8\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u6cbb\u3055\u306a\u3044\u6cbb\u7642<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u98df\u4e8b\u3092\u5909\u3048\u305a\u306b\u3001\u305f\u3060\u5358\u306b\u85ac\u3060\u3051\u3092\u98f2\u307f\u7d9a\u3051\u308b\u3088\u3046\u306a\u6cbb\u7642\u3092\u884c\u3063\u3066\u3044\u308c\u3070\u9006\u8ee2\u306f\u96e3\u3057\u304f\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u307e\u305a\u306f\u3001\u7cd6\u8cea\u5236\u9650\u304c\u57fa\u672c\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u300cAssociation between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study\u300d<\/span><\/p>\n

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