{"id":18687,"date":"2022-04-18T08:34:30","date_gmt":"2022-04-17T23:34:30","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=18687"},"modified":"2022-04-18T08:34:30","modified_gmt":"2022-04-17T23:34:30","slug":"post-18687","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=18687","title":{"rendered":"\u30a2\u30e1\u30ea\u30ab\u5fc3\u81d3\u5354\u4f1a\u304c\u51fa\u3057\u305f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u75be\u60a3\u306b\u3064\u3044\u3066\u306e\u58f0\u660e\u3067\u7cd6\u8cea\u5236\u9650\u3092\u63a8\u5968"},"content":{"rendered":"

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Dietary Modification<\/span><\/p>\n

Beyond the benefit attributable to significant weight loss in ameliorating NASH (ie, \u226510% body weight reduction), some specific dietary recommendations may exert independent effects in reducing NASH beyond weight loss. Hypocaloric diets, whether low carbohydrate or low fat, reduce intrahepatocellular lipid content, although the former results in faster (eg, within 2 days) and more pronounced effects even in an isocaloric context. Restriction of high-fructose corn syrup intake to <20 g\/d has been shown to improve NASH even in the absence of weight loss. Sucrose-sweetened beverages are a significant source of fructose intake for many individuals. Consumption of a Mediterranean-like diet with a pattern of dietary consumption limited to 8 to 12 hours during the day and restriction of food before bedtime may be most advantageous in formulating dietary recommendations for NASH. Mediterranean-style dietary habits have been shown to reduce hepatic fat and to improve insulin sensitivity independently of exercise and weight loss.This is a particularly important consideration given the difficulty that many patients have achieving sustainable weight loss. Currently, the Mediterranean diet is the only specific dietary pattern recommended by the European Association for the Study of the Liver\/European Association for the Study of Diabetes\/European Association for the Study of Obesity clinical practice guidelines for the treatment of NAFLD and NASH. Fructose intake should be minimized because it aggravates weight gain, stimulates intrahepatic triglyceride accumulation, and has been associated with worsening fibrosis and progression to NASH among patients with NAFLD. Restriction of dietary fat intake may lower plasma triglyceride levels, particularly when the triglyceride concentration is severely elevated >800 to 1000 mg\/dL, but increased carbohydrate intake may increase triglyceride levels in some individuals with triglycerides in the range of 500 to 1000 mg\/dL. Consultation with a dietitian can be invaluable to educate patients and to facilitate optimization of dietary habits.<\/span><\/p>\n

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\u4e2d\u6027\u8102\u80aa\u304c800\u301c1000mg\/dL\u3092\u8d85\u3048\u308b\u3088\u3046\u306a\u4eba\u3067\u306f\u8102\u8cea\u5236\u9650\u304c\u5fc5\u8981\u3067\u3042\u308b\u304c\u3001500\u301c1000mg\/dL\u306e\u7a0b\u5ea6\u306e\u7bc4\u56f2\u3067\u3042\u308c\u3070\u3001\u7cd6\u8cea\u5236\u9650\u304c\u5fc5\u8981\u3067\u3042\u308b\u3088\u3046\u306a\u8a18\u8ff0\u306b\u3082\u601d\u3048\u307e\u3059\u306d\u3002<\/p>\n

\u300c\u6804\u990a\u58eb\u3068\u306e\u76f8\u8ac7\u306f\u3001\u60a3\u8005\u3092\u6559\u80b2\u3057\u3001\u98df\u751f\u6d3b\u306e\u6700\u9069\u5316\u3092\u4fc3\u9032\u3059\u308b\u305f\u3081\u306b\u975e\u5e38\u306b\u8cb4\u91cd\u306a\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/span>\u300d<\/p>\n

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 <\/p>\n

\u300cNonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association\u300d<\/span><\/p>\n

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