{"id":19922,"date":"2022-10-04T13:07:42","date_gmt":"2022-10-04T04:07:42","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=19922"},"modified":"2022-10-04T13:07:42","modified_gmt":"2022-10-04T04:07:42","slug":"%e6%9c%80%e8%bf%91ldl%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%8b%e3%82%89lpa%e3%81%8a%e3%82%88%e3%81%b3apob%e3%81%ab%e3%82%b7%e3%83%95%e3%83%88%e3%81%97%e3%81%a6-3","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=19922","title":{"rendered":"\u6700\u8fd1LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304b\u3089Lp(a)\u304a\u3088\u3073ApoB\u306b\u30b7\u30d5\u30c8\u3057\u3066\u304d\u3066\u3044\u308b\u3000\u305d\u306e3"},"content":{"rendered":"

\u300c\u305d\u306e1<\/a>\u300d\u300c\u305d\u306e2<\/a>\u300d\u306e\u7d9a\u304d\u3067\u3059\u3002<\/p>\n

\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e88\u9632\u3001\u30ea\u30b9\u30af\u8efd\u6e1b\u306b\u306f\u80a5\u6e80\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u306f\u91cd\u8981\u3060\u3068\u601d\u3044\u307e\u3059\u3002Lp(a)\u306b\u95a2\u3057\u3066\u306f\u98df\u4e8b\u5236\u9650\u3001\u4f53\u91cd\u6e1b\u5c11\u3068\u3069\u306e\u3088\u3046\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f2\u578b\u7cd6\u5c3f\u75c5\u306e\u3042\u308b\u4eba\u3068\u306a\u3044\u4eba\u4e21\u65b9\u3067\u3001\u4f53\u91cd\u6e1b\u5c11\u3068Lp(a)\u306e\u95a2\u9023\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u30022\u578b\u7cd6\u5c3f\u75c5\u306e\u4e3b\u306b\u80a5\u6e80\u306e\u60a3\u8005131\u4eba\u306e\u96c6\u56e3\uff08\u30b3\u30db\u30fc\u30c81\uff09\u3068\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u80a5\u6e80\u60a3\u800530\u4eba\u306e\u96c6\u56e3\uff08\u30b3\u30db\u30fc\u30c82\uff09\u3068\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u80a5\u6e80\u60a3\u800537\u4eba\u306e\u96c6\u56e3\uff08\u30b3\u30db\u30fc\u30c83\uff09\u3001\u304a\u3088\u3073\u80a5\u6e80\u624b\u8853\u3092\u53d7\u3051\u305f2\u578b\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u80a5\u6e80\u60a3\u800526\u4eba\u306e\u96c6\u56e3\uff08\u30b3\u30db\u30fc\u30c84\uff09\u3001\u306e4\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u304c\u5bfe\u8c61\u3067\u3057\u305f\u3002<\/p>\n

\u30b3\u30db\u30fc\u30c81\u30682\u3067\u306f1 \u65e5\u3042\u305f\u308a\u7d043000kJ (750kcal) \u306e\u975e\u5e38\u306b\u4f4e\u30a8\u30cd\u30eb\u30ae\u30fc\u98df\u306e 8 \u9031\u9593\u306e\u98df\u4e8b\u304b\u3089\u59cb\u307e\u308a\u3001\u305d\u306e\u5f8c\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf\u3092 1 \u65e5\u3042\u305f\u308a\u7d045500kJ (1300kcal) \u307e\u3067 12 \u9031\u9593\u306b\u308f\u305f\u3063\u3066\u3086\u3063\u304f\u308a\u3068\u5897\u52a0\u3055\u305b\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u98df\u3067\u4f53\u91cd\u6e1b\u5c11\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u30b3\u30db\u30fc\u30c83\u3067\u306f\u3001\u904b\u52d5\u304c\u5968\u52b1\u3055\u308c\u3001\u4e3b\u8981\u6804\u990a\u7d20\u3068\u5fae\u91cf\u6804\u990a\u7d20\u306e\u542b\u6709\u91cf\u304c\u56fd\u306e\u98df\u4e8b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u6cbf\u3063\u305f\u72b6\u614b\u3067\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3068\u6bd4\u8f03\u3057\u30661\u65e5\u3042\u305f2000kJ\uff08500kcal\uff09\u5c11\u306a\u30443\u304b\u6708\u306e\u98df\u4e8b\u4ecb\u5165\u3092\u53d7\u3051\u307e\u3057\u305f\u3002<\/p>\n

\u30b3\u30db\u30fc\u30c84\u3067\u306f\u3001\u80a5\u6e80\u624b\u8853\u304c\u884c\u308f\u308c\u3001\u7279\u5b9a\u306e\u98df\u4e8b\u306f\u63a8\u5968\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n
\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5909\u6570<\/th>\n\u30b3\u30db\u30fc\u30c8 1 (\u00a0n<\/i>\u00a0\u00a0= 131)<\/th>\n\u30b3\u30db\u30fc\u30c8 2 (\u00a0n<\/i>\u00a0\u00a0= 30)<\/th>\n\u30b3\u30db\u30fc\u30c8 3 (\u00a0n<\/i>\u00a0\u00a0= 37)<\/th>\n\u30b3\u30db\u30fc\u30c8 4 (\u00a0n<\/i>\u00a0\u00a0= 26)<\/th>\n<\/tr>\n
\u524d<\/th>\n\u5f8c<\/th>\n\u524d<\/th>\n\u5f8c<\/th>\n\u524d<\/th>\n\u5f8c<\/th>\n\u524d<\/th>\n\u5f8c<\/th>\n<\/tr>\n<\/thead>\n
\u5e74\u9f62\u3001\u5e74\uff08\u7bc4\u56f2\uff09<\/td>\n54 (26\u201374)<\/td>\n\u2013<\/td>\n55 (34\u201370)<\/td>\n\u2013<\/td>\n42 (18\u201363)<\/td>\n\u2013<\/td>\n48 (34\u201359)<\/td>\n\u2013<\/td>\n<\/tr>\n
\u91cd\u91cf (kg)<\/td>\n105.0\u00b119.1<\/td>\n94.5\u00b117.3<\/span><\/td>\n103.2\u00b123.3<\/td>\n94.2 \u00b1 21.7<\/span><\/td>\n111.4\u00b117.1<\/td>\n104.3 \u00b1 16.7<\/span><\/td>\n124.0\u00b111.8<\/td>\n106.6\u00b111.2<\/span><\/td>\n<\/tr>\n
BMI (kg\/m\u00a02<\/sup>\u00a0)<\/td>\n36.8\u00b15.6<\/td>\n33.1\u00b15.2<\/span><\/td>\n34.8\u00b16.6<\/td>\n31.8\u00b16.6<\/span><\/td>\n38.4\u00b14.7<\/td>\n35.9\u00b14.5<\/span><\/td>\n43.7\u00b13.2<\/td>\n37.4 \u00b1 3.5<\/span><\/td>\n<\/tr>\n
\u80f4\u56f2\uff08cm\uff09<\/td>\n119.8\u00b112.9<\/td>\n110.8\u00b111.9<\/span><\/td>\n113.1\u00b112.3<\/td>\n106.0\u00b112.3<\/span><\/td>\n106.2\u00b115.1<\/td>\n98.3 \u00b1 13.8<\/span><\/td>\n\u2013<\/td>\n\u2013<\/td>\n<\/tr>\n
HbA1c (\u00a0%<\/sub>\u00a0)<\/td>\n7.7 (6.9\u20138.6)<\/td>\n7.0 (6.1\u20138.2)<\/span><\/td>\n7.5 (7.0\u20138.2)<\/td>\n6.6 (6.0\u20138.2)<\/span><\/td>\n5.5 (5.3\u20135.8)<\/td>\n5.4 (5.2\u20135.7)<\/span><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u7a7a\u8179\u6642\u8840\u7cd6 (mmol\/l)<\/td>\n8.8 (6.9\u201310.8)<\/td>\n7.3 (6.1\u20139.3)<\/span><\/td>\n8.7 (7.0\u201310.5)<\/td>\n7.4 (6.5\u20139.3)<\/td>\n5.3 (5.0\u20135.8)<\/td>\n5.1 (4.8\u20135.4)<\/span><\/td>\n5.1 (4.7\u20135.2)<\/td>\n4.9 (4.4\u20135.3)<\/td>\n<\/tr>\n
\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb (mmol\/l)<\/td>\n4.4 (3.7\u20135.1)<\/td>\n4.1 (3.5\u20134.8)<\/span><\/td>\n3.9 (3.6\u20135.1)<\/td>\n4.2 (3.5\u20135.5)<\/td>\n5.2 (4.3\u20135.7)<\/td>\n4.6 (4.1\u20135.2)<\/span><\/td>\n4.7 (3.8\u20135.8)<\/td>\n4.0 (3.5\u20134.9)<\/span><\/td>\n<\/tr>\n
LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb (mmol\/l)<\/td>\n2.5 (2.1\u20133.1)<\/td>\n2.4 (1.8\u20132.9)<\/span><\/td>\n2.4 (2.0\u20133.2)<\/td>\n2.2 (1.7\u20133.3)<\/td>\n3.4 (3.0\u20134.0)<\/td>\n3.1 (2.7\u20133.6)<\/span><\/td>\n2.8 (2.3\u20133.6)<\/td>\n2.3 (1.8\u20133.0)<\/span><\/td>\n<\/tr>\n
HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb (mmol\/l)<\/td>\n1.1 (1.0\u20131.3)<\/td>\n1.2 (1.0\u20131.4)<\/span><\/td>\n1.2 (1.0\u20131.5)<\/td>\n1.2 (1.1\u20131.5)<\/td>\n1.3 (1.1\u20131.4)<\/td>\n1.2 (1.1\u20131.4)<\/span><\/td>\n1.1 (1.0\u20131.3)<\/td>\n1.0 (0.9\u20131.2)<\/span><\/td>\n<\/tr>\n
\u4e2d\u6027\u8102\u80aa (mmol\/l)<\/td>\n1.8 (1.2\u20132.6)<\/td>\n1.4 (1.0\u20132.0)<\/span><\/td>\n1.5 (1.1\u20132.5)<\/td>\n1.4 (0.9\u20132.0)<\/td>\n1.3 (1.0\u20131.8)<\/td>\n1.1 (0.9\u20131.4)<\/span><\/td>\n1.2 (0.9\u20131.8)<\/td>\n1.2 (1.0\u20131.4)<\/td>\n<\/tr>\n
Lp(a) (nmol\/l)<\/td>\n40.9 (13.9\u2013159.5)<\/td>\n55.9 (23.0\u2013201.1)<\/span><\/td>\n56.9 (12.4\u2013148.9)<\/td>\n61.5 (20.4\u2013185.9)<\/span><\/td>\n27.0 (2.1\u201375.2)<\/td>\n45.2 (22.7\u201394.5)<\/span><\/td>\n36.4 (17.2\u201391.5)<\/td>\n20.6 (6.3\u2013104.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n

\u4e0a\u306e\u8868\u306f\u4ecb\u5165\u524d\u5f8c\u306e\u72b6\u614b\u3067\u3059\u3002\u3069\u306e\u30b0\u30eb\u30fc\u30d7\u3082\u5927\u304d\u304f\u4f53\u91cd\u6e1b\u5c11\u3001BMI\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u5927\u304d\u304fHBA1c\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u4e2d\u6027\u8102\u80aa\u306f\u5897\u52a0\u3057\u305f\u308a\u6e1b\u5c11\u3057\u305f\u308a\u3001\u5909\u5316\u3057\u306a\u3044\u3067\u3001\u3068\u8272\u3005\u3067\u3059\u3002<\/p>\n

\u3055\u3066Lp(a)\u306f\u30b3\u30db\u30fc\u30c84\u4ee5\u5916\u3067\u5927\u304d\u304f\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u30b3\u30db\u30fc\u30c81\u306e\u305d\u308c\u305e\u308c\u306e\u60a3\u8005\u306eLp(a)\u306e\u5909\u5316\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u5f53\u7136\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001Lp(a)\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u4eba\u3082\u3044\u307e\u3057\u305f\u304c\u3001\u591a\u304f\u306f\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u5897\u52a0\u306e\u5272\u5408\u3082\u500b\u3005\u3067\u5927\u304d\u306a\u9055\u3044\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u65e5\u672c\u306e\u5358\u4f4d(mg\/dL)\u306b\u3059\u308b\u306b\u306f2.1\u3067\u5272\u3063\u3066\u304f\u3060\u3055\u3044\u3002\u6700\u3082\u5897\u52a0\u3057\u305f\u4eba\u3067\u306f\u304a\u3088\u305d250nmol\/L\u306e\u5897\u52a0\u306a\u306e\u3067\u3001120mg\/dL\u304f\u3089\u3044\u5897\u52a0\u3057\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u30b3\u30db\u30fc\u30c8\u5225\u306e\u5909\u5316\u3067\u3059\u3002\u25cb\u304c\u4f53\u91cd\u5909\u5316\u3067\u3059\u3002\u25cf\u304cLp(a)\u306e\u5909\u5316\u3067\u3059\u3002\u30b3\u30db\u30fc\u30c81\uff5e3\u306eLp(a)\u5897\u52a0\u306e\u4e2d\u592e\u5024\u306f11.9\uff5e14.8nmol\/l\u7a0b\u5ea6\u306a\u306e\u3067\u3001\u65e5\u672c\u306e\u5358\u4f4d\u3067\u8003\u3048\u308c\u30706\uff5e7mg\/dL\u7a0b\u5ea6\u306e\u5897\u52a0\u306b\u3059\u304e\u307e\u305b\u3093\u304c\u3001\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30b3\u30db\u30fc\u30c84\u3060\u3051\u306fLp(a)\u306f\u6709\u610f\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u6e1b\u5c11\u50be\u5411\u3067\u3057\u305f\u3002<\/p>\n

\u305d\u3046\u3059\u308b\u3068\u3001\u4f53\u91cd\u6e1b\u5c11\u3068Lp(a)\u306f\u95a2\u9023\u3057\u3066\u304a\u3089\u305a\u3001\u4f53\u91cd\u6e1b\u5c11\u3067\u306f\u306a\u304f\u98df\u4e8b\u5236\u9650\u3001\u3064\u307e\u308a\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u306b\u3088\u308aLp(a)\u304c\u5897\u52a0\u3057\u305f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u73fe\u5728\u306e\u4e00\u822c\u7684\u306a\u8003\u3048\u65b9\u3067\u306f\u3001\u4f53\u91cd\u3092\u6e1b\u5c11\u3055\u305b\u308b\u98df\u4e8b\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\uff08\u30ab\u30ed\u30ea\u30fc\u5236\u9650\uff09\u3067\u3059\u3002\u305d\u308c\u304c\u6b63\u3057\u3044\u3068\u3057\u304b\u601d\u3063\u3066\u3044\u306a\u3044\u533b\u5e2b\u306f\u3001\u6b21\u306e\u3088\u3046\u306b\u8003\u3048\u308b\u3067\u3057\u3087\u3046\u3002\u300c\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306b\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u3055\u308c\u305f\u98df\u4e8b\u3092\u3057\u3066\u3044\u308b\u904e\u4f53\u91cd\u304a\u3088\u3073\u80a5\u6e80\u306e\u4eba\u306b\u3068\u3063\u3066\u306f\u3001Lp(a)\u304c\u5897\u52a0\u3059\u308b\u306e\u3067\u3001Lp(a) \u4f4e\u4e0b\u85ac\u3092\u98df\u4e8b\u4ecb\u5165\u306b\u8ffd\u52a0\u3059\u308b\u3053\u3068\u304c\u5fc5\u8981\u3060\uff01\u300d<\/p>\n

\u305d\u3057\u3066\u3001Lp(a)\u4f4e\u4e0b\u85ac\u304c\u767a\u58f2\u3055\u308c\u305f\u6681\u306b\u306f\u3001\u60a3\u8005\u306b\u306fLp(a)\u4f4e\u4e0b\u85ac\u304c\u51e6\u65b9\u3055\u308c\u308b\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u975e\u5e38\u306b\u3046\u307e\u304f\u8003\u3048\u3089\u308c\u305f\u30d3\u30b8\u30cd\u30b9\u30e2\u30c7\u30eb\u3067\u3059\u306d\u3002\u60a3\u8005\u306b\u306f\u75e9\u305b\u308d\uff01\u3068\u8a00\u3063\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u3092\u3055\u305b\u3066\u3001Lp(a)\u304c\u5897\u52a0\u3057\u305f\uff01\u3068\u8a00\u3063\u3066\u85ac\u3092\u51e6\u65b9\u3059\u308b\u3002\u305d\u3093\u306a\u4e16\u754c\u304c\u3082\u3046\u3059\u3050\u3084\u3063\u3066\u304f\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

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 <\/p>\n

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