{"id":20285,"date":"2022-10-19T18:35:26","date_gmt":"2022-10-19T09:35:26","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=20285"},"modified":"2022-10-19T18:36:53","modified_gmt":"2022-10-19T09:36:53","slug":"%e5%bf%83%e8%a1%80%e7%ae%a1%e7%96%be%e6%82%a3%e6%ad%bb%e4%ba%a1%e3%83%aa%e3%82%b9%e3%82%af%e3%82%92%e6%8e%a8%e5%ae%9a%e3%81%99%e3%82%8b%e3%81%ae%e3%81%ab%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=20285","title":{"rendered":"\u5fc3\u8840\u7ba1\u75be\u60a3\u6b7b\u4ea1\u30ea\u30b9\u30af\u3092\u63a8\u5b9a\u3059\u308b\u306e\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9069\u5207\uff1f"},"content":{"rendered":"

\u5fc3\u8840\u7ba1\u75be\u60a3\u306f\u3044\u307e\u3060\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u305b\u3044\u306b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u30ea\u30b9\u30af\u3092\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u672c\u5f53\u306b\u5371\u967a\u56e0\u5b50\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u306f\u30011995\uff5e1997\u5e74\u306b\u30ce\u30eb\u30a6\u30a7\u30fc\u306b\u4f4f\u3093\u3067\u3044\u305f20\u6b73\u4ee5\u4e0a\u306e\u6210\u4eba\u3067\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u65e2\u77e5\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u304c\u306a\u304452,087\u4eba\uff08\u7537\u602724,235\u4eba\u3001\u5973\u602727,852\u4eba\uff09\u3067\u3059\u300210\u5e74\u9593\u306e\u8ffd\u8de1\u8abf\u67fb\u671f\u9593\u4e2d\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u95a2\u9023\u3092\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002\u5358\u4f4d\u3092\u65e5\u672c\u306e\u3082\u306e\u306b\u3059\u308b\u306b\u306f38.7\u3092\u304b\u3051\u307e\u3059\u30025.5mmol\/L\u306f\u7d04213mg\/dL\u3067\u3059\u3002\u65e5\u672c\u306e\u57fa\u6e96\u5024\u306f120\uff5e219mg\/dL\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f1000\u4eba\u5e74\u3042\u305f\u308a\u306e\u81f4\u6b7b\u7684\u306a\u5fc3\u8840\u7ba1\u75be\u60a3\u306e10\u5e74\u9593\u306e\u767a\u751f\u7387\u3067\u3059\u3002\u8d64\u304c5\uff05\u4ee5\u4e0a\u3001\u7dd1\u304c1\uff05\u672a\u6e80\u3067\u3059\u300240\u6b73\u672a\u6e80\u3067\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u3082\u8840\u5727\u3068\u3082\u95a2\u9023\u305b\u305a\u3001\u767a\u751f\u7387\u306f\u975e\u5e38\u306b\u4f4e\u3044\u3067\u3059\u300240\uff5e59\u6b73\u3067\u306f\u8840\u5727\u304c140\u4ee5\u4e0a\u3067\u3001\u55ab\u7159\u8005\u3067\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb5.5\u4ee5\u4e0a\u3067\u306f\u767a\u751f\u7387\u304c\u3084\u3084\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7537\u6027\u306e\u307f\u8840\u5727\u304c140\u4ee5\u4e0a\u3067\u3001\u55ab\u7159\u8005\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c5.5\u672a\u6e80\u3067\u3082\u767a\u751f\u7387\u304c\u3084\u3084\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u300260\uff5e74\u6b73\u3067\u306f\u55ab\u7159\u8005\u3001\u7279\u306b\u7537\u6027\u306e\u55ab\u7159\u8005\u3067\u767a\u751f\u7387\u304c\u9ad8\u304f\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u95a2\u4fc2\u306a\u3055\u305d\u3046\u3067\u3059\u3002\u8840\u5727\u3082\u95a2\u4fc2\u3042\u3063\u305f\u308a\u306a\u304b\u3063\u305f\u308a\u3067\u3059\u306d\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u95a2\u9023\u3059\u308b\u5168\u539f\u56e0\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002\u9752\u304c\u7537\u6027\u3001\u8d64\u304c\u5973\u6027\u3067\u3001\u5e74\u9f62\u3001\u55ab\u7159\u3001\u53ce\u7e2e\u671f\u8840\u5727\u3067\u8abf\u6574\u3057\u3066\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb5\u672a\u6e80\uff08\u7d04194mg\/dL\uff09\u3068\u6bd4\u3079\u3066\u30017\u4ee5\u4e0a\uff08\u7d04271mg\/dL\uff09\u3067\u30ea\u30b9\u30af\u306f\u9ad8\u304f\u306a\u3063\u3066\u3044\u306a\u3044\u3069\u3053\u308d\u304b\u3001\u5973\u6027\u3067\u306f\u30ea\u30b9\u30af\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u9006\u306b\u8a00\u3048\u3070\u5973\u6027\u306e\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4e0b\u3052\u306a\u3044\u65b9\u304c\u826f\u3044\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u95a2\u9023\u3059\u308b\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3068\u306f\u95a2\u9023\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3067\u3059\u304c\u3001\u3053\u308c\u307e\u305f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306f\u95a2\u9023\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u307e\u305f\u7537\u5973\u3068\u3082\u306b\u3001\u55ab\u7159\u8005\u3067\u3082\u975e\u55ab\u7159\u8005\u3067\u3082\u30015.5mmol\/L\u3092\u8d85\u3048\u308b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u6b7b\u4ea1\u7387\u306e\u5897\u52a0\u3068\u306f\u95a2\u9023\u304c\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n

\u4e00\u65b9\u3001\u55ab\u7159\u306f\u5927\u304d\u304f\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u6b7b\u56e0<\/th>\n\u55ab\u7159\u72b6\u6cc1<\/th>\n\u7537\u6027<\/th>\n\u5973\u6027<\/th>\n<\/tr>\n
HR (95% CI)<\/th>\nHR (95% CI)<\/th>\n<\/tr>\n<\/thead>\n
\u3059\u3079\u3066\u306e\u539f\u56e0<\/b><\/td>\n<\/tr>\n
\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n2.09 (1.71\u20132.55)<\/span><\/td>\n1.72 (1.29\u20132.30)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n
\u4f4e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n1.99 (1.76\u20132.24)<\/span><\/td>\n2.16 (1.87\u20132.48)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n
\u5fc3\u8840\u7ba1\u75be\u60a3<\/b><\/td>\n<\/tr>\n
\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n2.30 (1.61\u20133.29)<\/span><\/td>\n1.82 (0.91\u20133.64)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n
\u4f4e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n2.44 (1.98\u20133.00)<\/span><\/td>\n2.24 (1.73\u20132.91)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n
\u865a\u8840\u6027\u5fc3\u75be\u60a3<\/b><\/td>\n<\/tr>\n
\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n2.28 (1.34\u20133.90)<\/span><\/td>\n2.35 (0.80\u20136.95)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n
\u4f4e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u55ab\u7159<\/td>\n2.42 (1.80\u20133.25)<\/span><\/td>\n3.08 (2.07\u20134.58)<\/span><\/td>\n<\/tr>\n
\u7981\u7159<\/td>\n1.00<\/td>\n1.00<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u3092\u898b\u3066\u660e\u3089\u304b\u306e\u3088\u3046\u306b\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u304f\u3066\u3082\u4f4e\u304f\u3066\u3082\u3001\u7981\u7159\u8005\u3068\u6bd4\u8f03\u3059\u308b\u3068\u55ab\u7159\u8005\u3067\u306f\u5927\u304d\u304f\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n

\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u3068\u901a\u5e38\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001LDL\u3082\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u5b9f\u969b\u306b\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u306f\u95a2\u9023\u3057\u3066\u3044\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u75be\u60a3\u304c\u85ac\u304a\u3088\u3073\u4f01\u696d\u3068\u5f37\u304f\u7d50\u3073\u3064\u304f\u3068\u771f\u5b9f\u304c\u637b\u3058\u66f2\u3052\u3089\u308c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u4f5c\u3089\u308c\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304c\u4f5c\u3089\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u69cb\u56f3\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3068\u305d\u306e\u30ef\u30af\u30c1\u30f3\u306e\u69cb\u56f3\u3068\u4e00\u7dd2\u3067\u3059\u3002<\/p>\n

\u5fc3\u8840\u7ba1\u75be\u60a3\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u907f\u3051\u305f\u3044\u306e\u3067\u3042\u308c\u3070\u3001\u307e\u305a\u306f\u7981\u7159\u3068\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u300cIs the use of cholesterol in mortality risk algorithms in clinical guidelines valid? Ten years prospective data from the Norwegian HUNT 2 study\u300d<\/span><\/p>\n

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