{"id":20642,"date":"2022-11-15T07:37:27","date_gmt":"2022-11-14T22:37:27","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=20642"},"modified":"2022-11-15T07:37:27","modified_gmt":"2022-11-14T22:37:27","slug":"%e3%81%9d%e3%82%8c%e3%81%a7%e3%82%82%e3%82%aa%e3%83%9f%e3%82%af%e3%83%ad%e3%83%b3%e5%af%be%e5%bf%9c%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%82%92%e6%8e%a5%e7%a8%ae%e3%81%97%e3%81%be%e3%81%99%e3%81%8b","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=20642","title":{"rendered":"\u305d\u308c\u3067\u3082\u30aa\u30df\u30af\u30ed\u30f3\u5bfe\u5fdc\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u307e\u3059\u304b\uff1f"},"content":{"rendered":"

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\"\"<\/a><\/p>\n

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\"\"<\/a><\/p>\n

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\"\"<\/a><\/p>\n

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\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u611f\u67d3\u304c1\u56de\u30012\u56de\u30013\u56de\u4ee5\u4e0a\u306e\u5165\u9662\u3068\u5f8c\u907a\u75c7\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002\u78ba\u304b\u306b\u611f\u67d3\u56de\u6570\u304c\u5897\u52a0\u3059\u308b\u3054\u3068\u306b\u30ea\u30b9\u30af\u306f\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u611f\u67d3\u3057\u3066\u3044\u306a\u3044\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001\u611f\u67d3\u304c 1 \u56de\u3057\u304b\u306a\u3044\u4eba\u306f\u3001\u5c11\u306a\u304f\u3068\u30821\u3064\u306e\u5f8c\u907a\u75c7\u306e\u30ea\u30b9\u30af\u304c1.37\u500d\u9ad8\u304f\u30012\u56de\u611f\u67d3\u3057\u305f\u4eba\u306f2.07\u500d\u30013\u56de\u4ee5\u4e0a\u611f\u67d3\u3057\u305f\u4eba\u306f2.35\u500d\u3067\u3057\u305f\u3002\u611f\u67d3\u3057\u3066\u3044\u306a\u3044\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u30663\u56de\u4ee5\u4e0a\u611f\u67d3\u3057\u305f\u4eba\u306e\u5165\u9662\u7387\u306f7.75\u500d\u3067\u3057\u305f\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Characteristic<\/td>\nNon-infected control
\n(N=5,334,729)<\/td>\n		No reinfection
\n(N=443,588)<\/td>\n		Reinfection
\n(N=40,947)<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
Age (years), mean (SD)<\/td>\n63.46 (16.56)<\/td>\n60.01 (15.82)<\/td>\n60.12 (15.54)<\/td>\n<\/tr>\n
Race, N (%)<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0\u00a0 White<\/td>\n3859677 (72.35)<\/td>\n310689 (70.04)<\/td>\n26185 (63.95)<\/td>\n<\/tr>\n
\u00a0\u00a0 Black<\/td>\n947981 (17.77)<\/td>\n95460 (21.52)<\/td>\n11183 (27.31)<\/td>\n<\/tr>\n
\u00a0\u00a0 Other<\/td>\n527071 (9.88)<\/td>\n37439 (8.44)<\/td>\n3579 (8.74)<\/td>\n<\/tr>\n
Sex, N (%)<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0\u00a0 Male<\/td>\n4806591 (90.1)<\/td>\n387607 (87.38)<\/td>\n35493 (86.68)<\/td>\n<\/tr>\n
\u00a0\u00a0 Female<\/td>\n528138 (9.9)<\/td>\n55981 (12.62)<\/td>\n5454 (13.32)<\/td>\n<\/tr>\n
ADI, mean SD<\/td>\n53.23 (18.76)<\/td>\n53.81 (18.24)<\/td>\n52.23 (18.67)<\/td>\n<\/tr>\n
Smoking status, N (%)<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0\u00a0 Never<\/td>\n2460911 (46.13)<\/td>\n201167 (45.35)<\/td>\n19024 (46.46)<\/td>\n<\/tr>\n
\u00a0\u00a0 Former<\/td>\n1541203 (28.89)<\/td>\n135028 (30.44)<\/td>\n12415 (30.32)<\/td>\n<\/tr>\n
\u00a0\u00a0 Current<\/td>\n1332615 (24.98)<\/td>\n107393 (24.21)<\/td>\n9508 (23.22)<\/td>\n<\/tr>\n
Long-term care, N (%)<\/td>\n39477 (0.74)<\/td>\n11666 (2.63)<\/td>\n2768 (6.76)<\/td>\n<\/tr>\n
Systolic blood pressure (mmHg), mean (SD)<\/td>\n131.79 (16.38)<\/td>\n132.38 (17.95)<\/td>\n132.6 (18.69)<\/td>\n<\/tr>\n
Diastolic blood pressure, (mmHg) mean (SD)<\/td>\n77.14 (9.74)<\/td>\n78.48 (10.81)<\/td>\n78.45 (11.25)<\/td>\n<\/tr>\n
Estimated glomerular filtration rate (mL\/min\/1.73m2), mean (SD)<\/td>\n78.68 (19.56)<\/td>\n79.78 (21.47)<\/td>\n78.75 (23.30)<\/td>\n<\/tr>\n
BMI, mean (SD)<\/td>\n29.93 (5.33)<\/td>\n31.01 (6.05)<\/td>\n30.95 (6.19)<\/td>\n<\/tr>\n
Immunocompromised status, N (%)<\/td>\n136569 (2.56)<\/td>\n19474 (4.39)<\/td>\n3206 (7.83)<\/td>\n<\/tr>\n
Cerebrovascular disease, N (%)<\/td>\n297678 (5.58)<\/td>\n34689 (7.82)<\/td>\n4459 (10.89)<\/td>\n<\/tr>\n
Cancer, N(%)<\/td>\n112029 (2.1)<\/td>\n14062 (3.17)<\/td>\n1802 (4.40)<\/td>\n<\/tr>\n
Anxiety, N (%)<\/td>\n507333 (9.51)<\/td>\n66893 (15.08)<\/td>\n8890 (21.71)<\/td>\n<\/tr>\n
Chronic kidney disease, N (%)<\/td>\n432647 (8.11)<\/td>\n49194 (11.09)<\/td>\n6302 (15.39)<\/td>\n<\/tr>\n
Cardiovascular disease, N (%)<\/td>\n770868 (14.45)<\/td>\n81620 (18.4)<\/td>\n9819 (23.98)<\/td>\n<\/tr>\n
Dementia, N (%)<\/td>\n196318 (3.68)<\/td>\n25950 (5.85)<\/td>\n3902 (9.53)<\/td>\n<\/tr>\n
Depression, N (%)<\/td>\n504132 (9.45)<\/td>\n67558 (15.23)<\/td>\n8460 (20.66)<\/td>\n<\/tr>\n
Diabetes mellitus type 2, N (%)<\/td>\n1331015 (24.95)<\/td>\n141371 (31.87)<\/td>\n14802 (36.15)<\/td>\n<\/tr>\n
Lung disease, N (%)<\/td>\n669508 (12.55)<\/td>\n76741 (17.3)<\/td>\n9201 (22.47)<\/td>\n<\/tr>\n
Peripheral artery disease, N (%)<\/td>\n71485 (1.34)<\/td>\n9315 (2.1)<\/td>\n1368 (3.34)<\/td>\n<\/tr>\n
Receipt of seasonal influenza vaccine in the 2 years prior, N (%)<\/td>\n2073076 (38.86)<\/td>\n216604 (48.83)<\/td>\n24626 (60.14)<\/td>\n<\/tr>\n
Number of inpatient visits, mean (SD)<\/td>\n0.13 (0.61)<\/td>\n0.34 (1.18)<\/td>\n0.82 (2.06)<\/td>\n<\/tr>\n
Number of outpatient visits, mean (SD)<\/td>\n2.52 (1.54)<\/td>\n3.47 (1.6)<\/td>\n4.17 (1.73)<\/td>\n<\/tr>\n
Number of blood chemistry panels, mean (SD)<\/td>\n2.7 (4.33)<\/td>\n4.7 (7.38)<\/td>\n8.2 (12.88)<\/td>\n<\/tr>\n
Number of unique medications, mean (SD)<\/td>\n8.03 (8.21)<\/td>\n12.58 (9.63)<\/td>\n16 (11.18)<\/td>\n<\/tr>\n
Week of enrollment, mean (SD)**<\/td>\n75.29 (28.65)<\/td>\n78.51 (27.60)<\/td>\n47.90 (22.91)<\/td>\n<\/tr>\n
Average duration of follow-up, mean (SD)<\/td>\n110.80 (69.75)<\/td>\n104.93 (69.98)<\/td>\n157.89 (46.80)<\/td>\n<\/tr>\n
Time between infections, mean (SD)<\/td>\n192.37 (113.68)<\/td>\n187.04 (108.69)<\/td>\n240.94 (142.08)<\/td>\n<\/tr>\n
HHS region SARS-CoV-2 variant Delta proportion*, mean (SD)<\/td>\nNA<\/td>\n0.24 (0.4)<\/td>\n0.11 (0.3)<\/td>\n<\/tr>\n
HHS region SARS-CoV-2 variant Omicron proportion*, mean (SD)<\/td>\nNA<\/td>\n0.33 (0.45)<\/td>\n0.03 (0.16)<\/td>\n<\/tr>\n
Number of inpatient medicare usage, mean (SD)<\/td>\n0.04 (0.2)<\/td>\n0.03 (0.18)<\/td>\n0.04 (0.2)<\/td>\n<\/tr>\n
Number of outpatient medicare usage, mean (SD)<\/td>\n0.16 (0.36)<\/td>\n0.09 (0.29)<\/td>\n0.07 (0.26)<\/td>\n<\/tr>\n
Vaccination<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0\u00a0 No vaccination, N (%)<\/td>\n3262719 (61.16)<\/td>\n275690 (62.15)<\/td>\n35657 (87.08)<\/td>\n<\/tr>\n
\u00a0\u00a0 One vaccination, N (%)<\/td>\n376098 (7.05)<\/td>\n37128 (8.37)<\/td>\n1552 (3.79)<\/td>\n<\/tr>\n
\u00a0\u00a0 Two vaccinations, N (%)<\/td>\n1177908 (22.08)<\/td>\n93508 (21.08)<\/td>\n3263 (7.97)<\/td>\n<\/tr>\n
\u00a0\u00a0 Three or more vaccinations, N (%)<\/td>\n518002 (9.71)<\/td>\n37261 (8.4)<\/td>\n475 (1.16)<\/td>\n<\/tr>\n
Average hospital bed capacity*, mean (SD)<\/td>\n0.42 (0.14)<\/td>\n0.42 (0.14)<\/td>\n0.42 (0.14)<\/td>\n<\/tr>\n
Total bed capacity*, mean (SD)<\/td>\n466.25 (299.06)<\/td>\n473.62 (301.26)<\/td>\n491.82 (304.64)<\/td>\n<\/tr>\n
Hospitalization during acute phase of first infection, N (%)<\/td>\nNA<\/td>\n39036 ( 8.8 )<\/td>\n7280 ( 17.78 )<\/td>\n<\/tr>\n
Admittance to intensive care unit during acute phase of first infection, N (%)<\/td>\nNA<\/td>\n10025 ( 2.26 )<\/td>\n1978 ( 4.83 )<\/td>\n<\/tr>\n
COVID Treatment, Immunomudulators, N (%)<\/td>\nNA<\/td>\n54606 ( 12.31 )<\/td>\n7051 ( 17.22 )<\/td>\n<\/tr>\n
COVID Treatment, Antivirals, N (%)<\/td>\nNA<\/td>\n21337 ( 4.81 )<\/td>\n2686 ( 6.56 )<\/td>\n<\/tr>\n
COVID Treatment, Antibodies, N (%)<\/td>\nNA<\/td>\n6831 ( 1.54 )<\/td>\n446 ( 1.09 )<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u56fd\u6c11\u3092\u9a19\u3059\u6297\u4f53\u4fa1\u3055\u3048\u5927\u3057\u3066\u4e0a\u304c\u3089\u306a\u3044\u3001\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u306a\u3044\u3001\u526f\u4f5c\u7528\u3082\u591a\u3044\u3001\u30cd\u30ba\u30df\u3055\u3093\u3067\u3057\u304b\u8a66\u3057\u3066\u3044\u306a\u3044\u4eba\u4f53\u5b9f\u9a13\u30ef\u30af\u30c1\u30f3\u3002<\/p>\n

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 <\/p>\n

\u300cBivalent BNT162b2mRNA original\/Omicron BA.4-5 booster vaccination: adverse reactions and inability to work compared to the monovalent COVID-19 booster\u300d<\/span><\/p>\n

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