{"id":20822,"date":"2022-12-07T08:41:54","date_gmt":"2022-12-06T23:41:54","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=20822"},"modified":"2022-12-07T08:41:54","modified_gmt":"2022-12-06T23:41:54","slug":"alp%ef%bc%88%e3%82%a2%e3%83%ab%e3%82%ab%e3%83%aa%e3%83%95%e3%82%a9%e3%82%b9%e3%83%95%e3%82%a1%e3%82%bf%e3%83%bc%e3%82%bc%ef%bc%89%e3%81%8c%e9%ab%98%e3%81%84%e3%81%93%e3%81%a8%e3%81%8c%e6%84%8f-2","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=20822","title":{"rendered":"ALP\uff08\u30a2\u30eb\u30ab\u30ea\u30d5\u30a9\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\uff09\u304c\u9ad8\u3044\u3053\u3068\u304c\u610f\u5473\u3059\u308b\u3053\u3068\u306f\u3000\u305d\u306e2"},"content":{"rendered":"<p>\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=20732\" target=\"_blank\" rel=\"noopener\">\u305d\u306e1<\/a>\u300d\u3067\u306f\u3001ALP\u3068\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u66f8\u304d\u307e\u3057\u305f\u3002\u3082\u3046\u3061\u3087\u3063\u3068\u9055\u3046\u7814\u7a76\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u795e\u7d4c\u5b66\u7684\u306b\u5065\u5eb7\u306a1,011\u4eba\u306e\u4eba\u306e\u8840\u7ba1\u5371\u967a\u56e0\u5b50\u3001\u8133\u306eMRI\u3001MR\u8840\u7ba1\u9020\u5f71\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u7121\u75c7\u5019\u6027\u30e9\u30af\u30ca\u6897\u585e (SLI) \u304a\u3088\u3073\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u8133\u767d\u8cea\u904e\u4fe1\u53f7 (MS-cWMH) \u306e\u5b58\u5728\u306f\u3001\u8133MRI\u4e0a\u306e\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\u306e\u6307\u6a19\u3068\u3057\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u982d\u84cb\u5916\u52d5\u8108\u72ed\u7a84 (ECAS) 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https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/b71951d388d6f60af1637e8e7a05635f.png?resize=1536%2C696&amp;ssl=1 1536w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/b71951d388d6f60af1637e8e7a05635f.png?resize=2048%2C928&amp;ssl=1 2048w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/b71951d388d6f60af1637e8e7a05635f.png?resize=1170%2C530&amp;ssl=1 1170w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/b71951d388d6f60af1637e8e7a05635f.png?w=1280 1280w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/b71951d388d6f60af1637e8e7a05635f.png?w=1920 1920w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306fALP\u3068\u7121\u75c7\u5019\u6027\u30e9\u30af\u30ca\u6897\u585e (SLI) \u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u8133\u767d\u8cea\u904e\u4fe1\u53f7 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(MS-cWMH)\u304c\u7d041.5\u500d\u3067\u3057\u305f\u3002\u305d\u3057\u3066ALP\u304c10\u5897\u52a0\u3059\u308b\u3068SLI\u306e\u53ef\u80fd\u6027\u306f5\uff05\u3001MS-cWMH\u306e\u53ef\u80fd\u6027\u306f3\uff05\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"20824\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=20824\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?fit=2000%2C830&amp;ssl=1\" data-orig-size=\"2000,830\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"ALP\u8133\u6897\u585epone.0143355.g002\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?fit=300%2C125&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?fit=640%2C266&amp;ssl=1\" class=\"alignnone size-full wp-image-20824\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=640%2C266\" alt=\"\" width=\"640\" height=\"266\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?w=2000&amp;ssl=1 2000w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=300%2C125&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=1024%2C425&amp;ssl=1 1024w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=768%2C319&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=1536%2C637&amp;ssl=1 1536w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?resize=1170%2C486&amp;ssl=1 1170w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?w=1280 1280w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/22addab39e868aace55a4df62c08d090.png?w=1920 1920w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u3001ALP\u3068SLI\u3001MS-cWMH\u306e\u5b58\u5728\u306e\u78ba\u7387\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002ALP\u304c\u5897\u52a0\u3059\u308b\u3068\u305d\u308c\u3089\u306e\u78ba\u7387\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u8133\u5c0f\u8840\u7ba1\u75be\u60a3 (cSVD) \u306f\u3001\u8133\u306e\u5c0f\u3055\u306a\u52d5\u8108\u306e\u9589\u585e\u3092\u4f34\u3046\u8133\u8840\u7ba1\u75be\u60a3\u3067\u3059\u3002\u30b5\u30a4\u30ec\u30f3\u30c8\u8133\u6897\u585e\uff08\u3044\u308f\u3086\u308b\u96a0\u308c\u8133\u6897\u585e\uff09\u304a\u3088\u3073\u8133\u767d\u8cea\u9ad8\u4fe1\u53f7 (cWMH) \u306f\u3001\u5065\u5eb7\u306a\u4eba\u306b\u3082\u6642\u6298\u898b\u3089\u308c\u308b\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\u306e\u30de\u30fc\u30ab\u30fc\u3067\u3059\u3002\u75c7\u72b6\u306f\u7121\u304f\u3066\u4e00\u898b\u5065\u5eb7\u306b\u898b\u3048\u307e\u3059\u304c\u3001\u5c06\u6765\u7684\u306a\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u304c3\u500d\u4ee5\u4e0a\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u306f2\u500d\u4ee5\u4e0a\u5897\u52a0\u3057\u307e\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12690219\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u3068<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12660385\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u3055\u3089\u306b\u6b63\u5e38\u7bc4\u56f2\u5185\u306eALP\u3067\u3042\u3063\u3066\u3082ALP\u304c\u9ad8\u3044\u5834\u5408\u3001\u8133\u5352\u4e2d\u5f8c\u306e\u9577\u671f\u306e\u6b7b\u4ea1\u7387\u3092\u9ad8\u3081\u307e\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21115954\/\" target=\"_blank\" 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style=\"color: #3366ff;\">\u300cAssociation between Serum Alkaline Phosphatase Level and Cerebral Small Vessel Disease\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u8840\u6e05\u30a2\u30eb\u30ab\u30ea\u30db\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\u30ec\u30d9\u30eb\u3068\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\u3068\u306e\u95a2\u9023\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26580067\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u305d\u306e1\u300d\u3067\u306f\u3001ALP\u3068\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u66f8\u304d\u307e\u3057\u305f\u3002\u3082\u3046\u3061\u3087\u3063\u3068\u9055\u3046\u7814\u7a76\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002 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