{"id":20941,"date":"2022-12-05T08:40:59","date_gmt":"2022-12-04T23:40:59","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=20941"},"modified":"2022-12-05T08:40:59","modified_gmt":"2022-12-04T23:40:59","slug":"%e6%b8%a1%e8%be%ba%e5%be%b9%e3%81%95%e3%82%93%e3%81%ae%e3%81%94%e5%86%a5%e7%a6%8f%e3%82%92%e3%81%8a%e7%a5%88%e3%82%8a%e3%81%84%e3%81%9f%e3%81%97%e3%81%be%e3%81%99","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=20941","title":{"rendered":"\u6e21\u8fba\u5fb9\u3055\u3093\u306e\u3054\u51a5\u798f\u3092\u304a\u7948\u308a\u3044\u305f\u3057\u307e\u3059"},"content":{"rendered":"

\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n

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\n\u300c\u592a\u967d\u306b\u307b\u3048\u308d!\u300d\u3067\u30c7\u30d3\u30e5\u30fc\u3055\u308c\u305f\u9803\u3068\u306f\u6253\u3063\u3066\u5909\u308f\u3063\u3066<\/span>
\n\u6669\u5e74(\u304a\u82e5\u3044\u3067\u3059\u304c)\u306f\u900f\u6790\u6cbb\u7642\u3082\u53d7\u3051\u3066\u3044\u305f\u305d\u3046\u3067\u3059\u3002<\/span><\/p>\n

\u3054\u51a5\u798f\u3092\u304a\u7948\u308a\u3044\u305f\u3057\u307e\u3059\u3002<\/span><\/p>\n

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1991\u5e74\u7cd6\u5c3f\u75c5
\n2012\u5e74\u5fc3\u7b4b\u6897\u585e
\n2013\u5e74\u6025\u6027\u81b5\u708e
\n2016\u5e74\u6162\u6027\u814e\u4e0d\u5168
\n2021\u5e74\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7<\/p>\n

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\u6e21\u8fba\u5fb9\u3055\u3093\u6b7b\u53bb\u300061\u6b73\u3000\u6557\u8840\u75c7\u3000\u75c5\u6c17\u3068\u95d8\u3063\u305f\u534a\u751f 10\u6708\u821e\u53f0\u306f\u307b\u3063\u305d\u308a\u3057\u305f\u59ff\u3000\u698a\u539f\u90c1\u6075\u3068\u304a\u3057\u3069\u308a\u592b\u5a66<\/span><\/h2>\n

12\/2(\u91d1) 10:15\u3000\uff08\u8a18\u4e8b\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

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1981\u5e74\u306b\u6587\u5b66\u5ea7\u7814\u7a76\u751f\u3068\u306a\u308a\u3001\u540c\u5e74\u306b20\u6b73\u3067\u300c\u592a\u967d\u306b\u307b\u3048\u308d\uff01\u300d\u3067\u30c7\u30d3\u30e5\u30fc\u3002\u6f14\u3058\u305f\u65b0\u4eba\u5211\u4e8b\u306e\u7af9\u672c\u6df3\u4e8c\u306f\u3001\u30e9\u30b0\u30d3\u30fc\u90e8\u51fa\u8eab\u306e\u305f\u3081\u611b\u79f0\u306f\u300c\u30e9\u30ac\u30fc\u300d\u3002\u4e8c\u679a\u76ee\u306e\u30eb\u30c3\u30af\u30b9\u3082\u76f8\u307e\u3063\u3066\u4e00\u8e8d\u4eba\u6c17\u3092\u96c6\u3081\u3001\u5287\u4e2d\u3067\u6b89\u8077\u3059\u308b85\u5e74\u307e\u30674\u5e74\u9593\u51fa\u6f14\u3057\u305f\u3002\u6b4c\u624b\u3068\u3057\u3066\u3082\u6d3b\u52d5\u3057\u300182\u5e74\u306e\u300c\u7d04\u675f\u300d\u306f\u30b0\u30ea\u30b3\u300c\u30a2\u30fc\u30e2\u30f3\u30c9\u30c1\u30e7\u30b3\u30ec\u30fc\u30c8\u300d\u306eCM\u30bd\u30f3\u30b0\u3068\u3057\u3066\u30d2\u30c3\u30c8\u3002\u660e\u308b\u3044\u30ad\u30e3\u30e9\u30af\u30bf\u30fc\u304b\u3089\u30d0\u30e9\u30a8\u30c6\u30a3\u30fc\u756a\u7d44\u306e\u53f8\u4f1a\u8005\u3068\u3057\u3066\u3082\u6d3b\u8e8d\u3057\u305f\u3002<\/span><\/p>\n

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2012\u5e74\u306b\u865a\u8840\u6027\u5fc3\u75be\u60a3<\/span>\u3068\u8a3a\u65ad\u3055\u308c\u30016\u6642\u9593\u306b\u3082\u53ca\u3076\u624b\u8853\u3092\u53d7\u3051\u305f\u3002\u5f53\u6642\u306f\u698a\u539f\u304c\u5065\u5eb7\u9762\u3092\u8003\u3048\u3066\u6599\u7406\u3092\u3064\u304f\u3063\u3066\u3044\u305f\u304c\u3001\u96a0\u308c\u3066\u66b4\u98f2\u66b4\u98df\u3092\u7d9a\u3051\u3066\u3044\u305f\u3053\u3068\u304c\u767a\u899a<\/span>\u3002\u751f\u6d3b\u3092\u6539\u3081\u308b\u3053\u3068\u3092\u8a93\u3063\u305f\u3002\u7fcc13\u5e74\u306b\u3082\u81b5\u708e\uff08\u3059\u3044\u3048\u3093\uff09<\/span>\u3067\u5165\u9662\u3002\u6628\u5e744\u6708\u306b\u3082\u5927\u52d5\u8108\u5f01\u72ed\u7a84\uff08\u304d\u3087\u3046\u3055\u304f\uff09\u75c7\u306e\u624b\u8853\u3092\u53d7\u3051\u305f<\/span>\u3002<\/span><\/p>\n

\u30d6\u30ed\u30b0\u306e\u6700\u5f8c\u306e\u66f4\u65b0\u306f\u5148\u670819\u65e5\u3002\u79cb\u7530\u770c\u5185\u3067\u5fc3\u81d3\u75c5\u306b\u95a2\u3059\u308b\u30d5\u30a9\u30fc\u30e9\u30e0\u306b\u30b2\u30b9\u30c8\u53c2\u52a0\u3057\u3001\u98df\u3079\u305f\u99c5\u5f01\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u3066\u3044\u305f\u3002<\/span><\/p>\n

61\u6b73\u3002\u82e5\u3044\u3067\u3059\u306d\u3002\u975e\u5e38\u306b\u6b8b\u5ff5\u3067\u3059\u3002\u304a\u305d\u3089\u304f\u306f\u6804\u990a\u6307\u5c0e\u3092\u53d7\u3051\u3066\u3044\u305f\u3067\u3057\u3087\u3046\u3051\u3069\u3001\u305d\u308c\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u98df\uff08\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\uff09\u3067\u3057\u3087\u3046\u3002\u4ee5\u524d\u306f\u672c\u5f53\u306b\u3072\u3069\u3044\u98df\u4e8b\u3060\u3063\u305f\u3088\u3046\u3067\u3059\u3002\u672c\u5f53\u304b\u3069\u3046\u304b\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u30011\u65e56\u98df\u3067\u30011.5\u30ea\u30c3\u30c8\u30eb\u306e\u30b3\u30fc\u30e9\u30921\u65e56\u672c\u98f2\u3080\u3001\u30ab\u30eb\u30d4\u30b9\u3092\u539f\u6db2\u3067\u98f2\u3080\u3001\u306a\u3069\u306e\u30a8\u30d4\u30bd\u30fc\u30c9\u3082\u76ee\u306b\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3042\u308b\u8a18\u4e8b<\/a>\u306b\u306f\u6b21\u306e\u3088\u3046\u306b\u66f8\u304b\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u30c0\u30a4\u30a8\u30c3\u30c8\u3082\u3001\u3044\u308d\u3044\u308d\u8a66\u3057\u3066\u307f\u305f\u3093\u3067\u3059\u3088\u3002\u30ef\u30ab\u30e1\u30c0\u30a4\u30a8\u30c3\u30c8\u3001\u30d0\u30ca\u30ca\u30c0\u30a4\u30a8\u30c3\u30c8\u3001\u3086\u3067\u5375\u30c0\u30a4\u30a8\u30c3\u30c8\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u30c0\u30a4\u30a8\u30c3\u30c8\u2026\u2026\u3002\u3069\u306e\u65b9\u6cd5\u3082\u3001\u78ba\u304b\u306b\uff13\uff5e\uff15\u338f\u7a0b\u5ea6\u3001\u81ea\u5206\u304c\u7acb\u3066\u305f\u76ee\u6a19\u307e\u3067\u306f\u75e9\u305b\u308b\u3093\u3067\u3059\u3002\u3067\u3082\u3001\u76ee\u6a19\u3092\u8a2d\u5b9a\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u30b4\u30fc\u30eb\u304c\u3042\u308b\u304b\u3089\u3001\u9054\u6210\u3059\u308b\u3068\u3054\u307b\u3046\u3073\u3092\u3042\u3052\u305f\u304f\u306a\u308b\u3002\u30ea\u30d0\u30a6\u30f3\u30c9\u3092\u8d77\u3053\u3057\u3066\u3057\u307e\u3046\u3002\u30c0\u30a4\u30a8\u30c3\u30c8\u3059\u308b\u305f\u3073\u306b\u3001\u592a\u3063\u3066\u304d\u305f\u308f\u3051\u3067\u3059\u3002<\/span><\/p>\n

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\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u3082\u5b9f\u969b\u306e\u3068\u3053\u308d\u306f\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3068\u540c\u69d8\u306a\u306e\u3067\u3001\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3060\u3068\u8003\u3048\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u95a2\u9023\u3092\u6307\u6458\u3059\u308b\u7814\u7a76\u306f\u305f\u304f\u3055\u3093\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u3088\u308a\u751f\u6210\u3055\u308c\u308bAGEs\uff08\u7d42\u672b\u7cd6\u5316\u7523\u7269\uff09\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u3068\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u3067\u3059\u3002\u5bfe\u8c61\u306f\u91cd\u5ea6\u306e\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u306e\u60a3\u8005126\u4eba\u3067\u300150\u4eba\u306f2\u578b\u7cd6\u5c3f\u75c5\u304c\u3042\u308a\u307e\u3059\u3002\u5e73\u5747\u5e74\u9f62\u306f68\uff5e70\u6b73\u3001BMI\u306f28\uff5e31\u7a0b\u5ea6\u3067\u3059\u3002\u7cd6\u5c3f\u75c5\u7fa4\u306e\u5e73\u5747HbA1c\u306f6.8\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u306f135\u3067\u3057\u305f\u3002<\/p>\n

\u5927\u52d5\u8108\u5f01\u5c16\u306e\u539a\u3055\u306f\u3001\u7cd6\u5c3f\u75c5\u7fa4\u306e\u65b9\u304c\u975e\u7cd6\u5c3f\u75c5\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u5206\u539a\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u4e0a\u5074\u304c\u975e\u7cd6\u5c3f\u75c5\u3001\u4e0b\u304c\u7cd6\u5c3f\u75c5\u306e\u5927\u52d5\u8108\u5f01\u3067\u3001AGEs\u3001AGE\u53d7\u5bb9\u4f53\uff08RAGE\uff09\u3001\u6d3b\u6027\u9178\u7d20\u7a2e\uff08ROS\uff09\u306a\u3069\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u5927\u52d5\u8108\u5f01\u306eAGEs\u306f\u975e\u7cd6\u5c3f\u75c5\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u7cd6\u5c3f\u75c5\u3067 6.6 \u500d\u9ad8\u304f\u3001AGE\u53d7\u5bb9\u4f531.8 \u500d\u9ad8\u304f\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002ROS\u3082\u7cd6\u5c3f\u75c5\u306b\u591a\u304f\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

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\u305d\u3046\u3067\u306a\u304f\u3066\u3082\u3001\u7cd6\u5c3f\u75c5\u3067\u306f\u514d\u75ab\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u708e\u75c7\u3082\u8d77\u3053\u3057\u3084\u3059\u3044\u72b6\u614b\u3067\u3059\u3002<\/p>\n

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\u307e\u305a\u306f\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002<\/p>\n

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 <\/p>\n

\u300cAccumulation of advanced glycation end products (AGEs) is associated with the severity of aortic stenosis in patients with concomitant type 2 diabetes\u300d<\/span><\/p>\n

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