{"id":21025,"date":"2023-06-14T16:03:05","date_gmt":"2023-06-14T07:03:05","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=21025"},"modified":"2023-06-14T16:03:05","modified_gmt":"2023-06-14T07:03:05","slug":"%e3%82%b9%e3%82%bf%e3%83%81%e3%83%b3%e3%81%af%e3%81%8c%e3%82%93%e3%81%ae%e3%83%aa%e3%82%b9%e3%82%af%e3%82%92%e5%a2%97%e5%8a%a0%e3%81%95%e3%81%9b%e3%82%8b%e5%8f%af%e8%83%bd%e6%80%a7","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=21025","title":{"rendered":"\u30b9\u30bf\u30c1\u30f3\u306f\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u53ef\u80fd\u6027"},"content":{"rendered":"<p>\u30b9\u30bf\u30c1\u30f3\u306f\u591a\u304f\u306e\u4eba\u306b\u51e6\u65b9\u3055\u308c\u3066\u3057\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3068\u304c\u3093\u306e\u95a2\u9023\u306f\u3044\u304f\u3064\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22156736\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u30b9\u30bf\u30c1\u30f3\u306e\u4e2d\u306e\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u306e\u8a66\u9a13\u3067\u306f\u30012\u3064\u306e\u8a66\u9a13\u306e\u305d\u308c\u305e\u308c\u3067\u306f\u6709\u610f\u306a\u95a2\u9023\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u30012\u3064\u3092\u5408\u308f\u305b\u3066\u5206\u6790\u3059\u308b\u3068\u3001\u76ae\u819a\u304c\u3093\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u30d7\u30e9\u30d0\u30b9\u30bf\u30c1\u30f3\u306e\u8a66\u9a13\u3067\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f1\u4eba\u306e\u60a3\u8005\u3001\u30d7\u30e9\u30d0\u30b9\u30bf\u30c1\u30f3\u7fa4\u3067\u306f12\u4eba\u306e\u60a3\u8005\u306b\u4e73\u304c\u3093\u304c\u767a\u751f\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3082\u3046\u4e00\u3064\u306e\u30d7\u30e9\u30d0\u30b9\u30bf\u30c1\u30f3\u306e\u8a66\u9a13\u3067\u30824\u5e74\u9593\u3067\u65b0\u305f\u306a\u304c\u3093\u306e\u8a3a\u65ad\u304c\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u308225\uff05\u5897\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u3068\u30a8\u30bc\u30c1\u30df\u30d6\u306e\u8a66\u9a13\u3067\u3082\u304c\u3093\u306e\u3088\u308b\u6b7b\u4ea1\u304c\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u308267\uff05\u5897\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f47,294\u4eba\u65e5\u672c\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30b9\u30bf\u30c1\u30f3\u3092\u4f7f\u3063\u305f\u7814\u7a76\u3067\u3059\u3002\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u3067\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u30686\u5e74\u9593\u3067\u3069\u3046\u306a\u3063\u305f\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/71dfaef8d78576497495e1a095f15dc3.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"23012\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=23012\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/71dfaef8d78576497495e1a095f15dc3.png?fit=1202%2C961&amp;ssl=1\" data-orig-size=\"1202,961\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u65e5\u672c\u4eba\u30b9\u30bf\u30c1\u30f3\" data-image-description=\"\" 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https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/71dfaef8d78576497495e1a095f15dc3.png?resize=1170%2C935&amp;ssl=1 1170w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f6\u5e74\u9593\u306e\u9593\u306e\u51a0\u52d5\u8108\u306e\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002\u78ba\u304b\u306b\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u3068\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306e\u9ad8\u5024\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4f4e\u5024\u3082\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u3066\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5024\u304c\u9ad8\u3044\u3053\u3068\u305d\u306e\u3082\u306e\u3088\u308a\u3082\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3084LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u9ad8\u3044\u3053\u3068\uff08\u3055\u3089\u306b\u30b9\u30bf\u30c1\u30f3\u3092\u4f7f\u3063\u3066\u3082\u9ad8\u3044\u3053\u3068\uff09\u306f\u975e\u5e38\u306b\u9ad8\u3044\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u3042\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"23011\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=23011\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?fit=1227%2C952&amp;ssl=1\" data-orig-size=\"1227,952\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u65e5\u672c\u4eba\u30b9\u30bf\u30c1\u30f32\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?fit=640%2C496&amp;ssl=1\" class=\"alignnone size-full wp-image-23011\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?resize=640%2C497\" alt=\"\" width=\"640\" height=\"497\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?w=1227&amp;ssl=1 1227w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?resize=300%2C233&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?resize=1024%2C794&amp;ssl=1 1024w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?resize=768%2C596&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/308c9e127add679e5317167a5b64cbf1.png?resize=1170%2C908&amp;ssl=1 1170w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u6b7b\u4ea1\u30ea\u30b9\u30af\u3067\u3059\u3002\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082U\u5b57\u578b\u306b\u306a\u3063\u3066\u3044\u3066\u3001\u9ad8\u5024\u3067\u3082\u4f4e\u5024\u3067\u3082\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4f4e\u5024\u3067\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"23010\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=23010\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?fit=1105%2C1277&amp;ssl=1\" data-orig-size=\"1105,1277\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u65e5\u672c\u4eba\u30b9\u30bf\u30c1\u30f3\u6b7b\u4ea1\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?fit=640%2C740&amp;ssl=1\" class=\"alignnone size-full wp-image-23010\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?resize=640%2C740\" alt=\"\" width=\"640\" height=\"740\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?w=1105&amp;ssl=1 1105w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?resize=260%2C300&amp;ssl=1 260w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?resize=886%2C1024&amp;ssl=1 886w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/06\/326d2a32df4ad26c9e99ea6b13a33d4d.png?resize=768%2C888&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u6b7b\u4ea1\u306e\u539f\u56e0\u3068\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u5225\u3067\u3059\u3002\u4e00\u756a\u4e0a\u306e\u300cCardiac\u300d\u3068\u3044\u3046\u306e\u306f\u5fc3\u81d3\u3067\u3059\u306e\u3067\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c160\u672a\u6e80\u3067\u30826\u500d\u4ee5\u4e0a\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4f4e\u3051\u308c\u3070\u4f4e\u3044\u307b\u3069\u5fc3\u81d3\u306b\u826f\u3044\u3068\u3044\u3046\u306e\u306f\u30a6\u30bd\u3067\u3059\u306d\u3002\u3055\u3066\u3001\u554f\u984c\u306f3\u3064\u76ee\u3001\u300cMalignancy\u300d\u3068\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u304c\u3093\u306e\u3053\u3068\u3067\u3059\u3002\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c160\uff5e179\u3067\u306f1.85\u500d\u3001160\u672a\u6e80\u3067\u306f3.16\u500d\u3082\u304c\u3093\u306b\u3088\u308b\u6b7b\u4ea1\u304c\u5897\u52a0\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002160\u672a\u6e80\u3067\u306e\u6b7b\u4ea1\u306e\u6700\u3082\u591a\u3044\u539f\u56e0\u3067\u3059\u3002<\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=19876\" target=\"_blank\" rel=\"noopener\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u3068\u304c\u3093\u306e\u30ea\u30b9\u30af\u306f\u4f4e\u4e0b\u3059\u308b<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c10mg\/dL\u6e1b\u5c11\u3059\u308b\u3054\u3068\u306b\u304c\u3093\u30ea\u30b9\u30af\u306f\u304a\u3088\u305d20\uff05\u4e0a\u6607\u3059\u308b\u8a08\u7b97\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u30b9\u30bf\u30c1\u30f3\u3092\u98f2\u3093\u3067\u3044\u308b\u4eba\u306f\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u77e5\u3063\u3066\u3044\u3066\u98f2\u3093\u3067\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p><span style=\"color: #3366ff;\">\u300cLarge scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u65e5\u672c\u4eba\u306e\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u60a3\u8005\u306b\u304a\u3051\u308b\u4f4e\u7528\u91cf\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u7642\u6cd5\u306b\u3088\u308b\u8840\u6e05\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6fc3\u5ea6\u3068\u51a0\u52d5\u8108\u30a4\u30d9\u30f3\u30c8\u3068\u306e\u95a2\u4fc2\u306b\u95a2\u3059\u308b\u5927\u898f\u6a21\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12499611\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b9\u30bf\u30c1\u30f3\u306f\u591a\u304f\u306e\u4eba\u306b\u51e6\u65b9\u3055\u308c\u3066\u3057\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3068\u304c\u3093\u306e\u95a2\u9023\u306f\u3044\u304f\u3064\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u3053\u3053\u53c2\u7167\uff09 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