{"id":21428,"date":"2023-01-16T07:54:33","date_gmt":"2023-01-15T22:54:33","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=21428"},"modified":"2023-01-16T07:54:33","modified_gmt":"2023-01-15T22:54:33","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%af%e8%82%ba%e5%a1%9e%e6%a0%93%e7%97%87%e3%82%84%e8%84%b3%e6%a2%97%e5%a1%9e","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=21428","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u30ef\u30af\u30c1\u30f3\u306f\u80ba\u585e\u6813\u75c7\u3084\u8133\u6897\u585e\u3092\u5897\u52a0\u3055\u305b\u308b\uff1f"},"content":{"rendered":"<p>\u6628\u5e74\u672b\u304b\u3089\u4eca\u5e74\u306b\u5165\u3063\u3066\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u98a8\u5411\u304d\u304c\u5909\u308f\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u660e\u3089\u304b\u306b\u6709\u5bb3\u6027\u306a\u3069\u306e\u5831\u544a\u3001\u8a18\u4e8b\u304c\u5897\u52a0\u3057\u3066\u304d\u305f\u3088\u3046\u306b\u601d\u3048\u307e\u3059\u3002<\/p>\n<p>30,712,101\u4eba\u306e65\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u3092\u30ab\u30d0\u30fc\u3059\u308b\u30a2\u30e1\u30ea\u30ab\u30e1\u30c7\u30a3\u30b1\u30a2 &amp; \u30e1\u30c7\u30a3\u30b1\u30a4\u30c9 \u30b5\u30fc\u30d3\u30b9 \u30bb\u30f3\u30bf\u30fc\uff08CMS\uff09\u306e\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3066\u3001\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e14\u306e\u7d50\u679c\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u30022020\u5e7412\u670811\u65e5\u304b\u30892022\u5e741\u670815\u65e5\u307e\u3067\u306e\u30c7\u30fc\u30bf\u306b\u306f\u3001\u5408\u8a0834,639,937\u56de\u306e\u6295\u4e0e\u3092\u53d7\u3051\u305f17,411,342\u4eba\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u5206\u6790\u306e\u7d50\u679c\u306f\u3001\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u3067\u80ba\u585e\u6813\u75c7\u306e\u30ea\u30b9\u30af\u306f1.54\u500d\u3001\u6025\u6027\u5fc3\u7b4b\u6897\u585e1.42\u500d\u3001\u64ad\u7a2e\u6027\u8840\u7ba1\u5185\u51dd\u56fa\u75c7\u5019\u7fa4\uff08DIC\uff091.91\u500d\u3001\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7 \uff08 ITP\uff091.44\u500d\u3067\u3057\u305f\u3002<\/p>\n<p>\u3069\u308c\u3082\u8840\u7ba1\u304a\u3088\u3073\u8840\u6813\u304c\u95a2\u308f\u308b\u3088\u3046\u306a\u526f\u4f5c\u7528\u3070\u304b\u308a\u3067\u3059\u306d\u3002<\/p>\n<p>\u3055\u3089\u306b\u3001\u3064\u3044\u5148\u65e5\u3001CDC\uff08\u30a2\u30e1\u30ea\u30ab\u75be\u75c5\u4e88\u9632\u7ba1\u7406\u30bb\u30f3\u30bf\u30fc\uff09\u3068FDA\uff08\u30a2\u30e1\u30ea\u30ab\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff09\u306f\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u767a\u8868\u3092\u884c\u3044\u307e\u3057\u305f\u3002\uff08<a href=\"https:\/\/www.fda.gov\/vaccines-blood-biologics\/safety-availability-biologics\/cdc-and-fda-identify-preliminary-covid-19-vaccine-safety-signal-persons-aged-65-years-and-older\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u3053\u306e\u767a\u8868\u306f\u73fe\u5728\u306e\u6700\u65b0\u306e2\u4fa1\u30ef\u30af\u30c1\u30f3\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3001\u30d5\u30a1\u30a4\u30b6\u30fc\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u306e2\u4fa1\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f65\u6b73\u4ee5\u4e0a\u306e\u4eba\u3067\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c22\uff5e44\u65e5\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c21\u65e5\u307e\u3067\u3067\u865a\u8840\u6027\u8133\u5352\u4e2d\uff08\u8133\u6897\u585e\uff09\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304b\u3063\u305f\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002\u3064\u307e\u308a\u3001\u30ef\u30af\u30c1\u30f3\u3068\u8133\u6897\u585e\u306e\u767a\u75c7\u306b\u56e0\u679c\u95a2\u4fc2\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3053\u308c\u307e\u305f\u8840\u6813\u7cfb\u306e\u526f\u4f5c\u7528\u3067\u3059\u306d\u3002\u3053\u308c\u304b\u3089\u8abf\u67fb\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u3087\u3046\u304c\u3001\u305d\u306e\u9593\u3082\u63a5\u7a2e\u3092\u4e2d\u6b62\u3059\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3072\u3069\u3044\u8a71\u3067\u3059\u3002<\/p>\n<p>CDC\u306f\u3053\u306e\u767a\u8868\u3067\u3001\u900f\u660e\u6027\u3092\u5f37\u8abf\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u672c\u5f53\u306bCDC\u3084FDA\u304c\u900f\u660e\u6027\u3092\u4fdd\u3063\u3066\u3044\u308b\u306a\u3093\u3066\u601d\u3048\u307e\u305b\u3093\u3002\u3061\u3087\u3063\u3068\u3057\u305f\u5b89\u5168\u6027\u306e\u7591\u5ff5\u3092\u767a\u8868\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u300c\u3061\u3083\u3093\u3068\u3059\u3079\u3066\u96a0\u3055\u305a\u767a\u8868\u3057\u3066\u3044\u307e\u3059\u300d\u611f\u3092\u51fa\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u3082\u601d\u3048\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u3088\u3046\u306a\u767a\u8868\u3082\u305b\u3056\u308b\u3092\u5f97\u306a\u3044\u307b\u3069\u3001\u69d8\u3005\u306a\u554f\u984c\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u3082\u4e8b\u5b9f\u3067\u3057\u3087\u3046\u3002\u3082\u3046\u96a0\u305b\u306a\u304f\u306a\u3063\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u305d\u3057\u3066\u3001\u6700\u5f8c\u306b\u306f\u5b89\u5168\u6027\u306b\u554f\u984c\u304c\u306a\u3044\u3053\u3068\u304c\u7e70\u308a\u8fd4\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3082\u3046\u3046\u3093\u3056\u308a\u3067\u3059\u3002<\/p>\n<p>The NEW ENGLAND JOURNAL of MEDICINE\u3068\u3044\u3046\u6709\u540d\u306a\u6a29\u5a01\u306e\u3042\u308b\u533b\u5b66\u96d1\u8a8c\u3067\u3055\u3048\u3001\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3078\u306e\u8b66\u544a\u6587\u3092\u8f09\u305b\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\uff08<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMp2215780\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u3053\u306e\u6587\u306b\u306f\u3001\u5909\u7570\u304c\u3069\u3093\u3069\u3093\u9032\u3080\u306e\u3067\u3001\u30ef\u30af\u30c1\u30f3\u304c\u8ffd\u3044\u4ed8\u3044\u3066\u3044\u306a\u3044\u3053\u3068\u3084\u3001\u305a\u3063\u3068\u524d\u304b\u3089\u8a00\u308f\u308c\u3066\u3044\u308b\u6297\u539f\u539f\u7f6a\u306b\u3064\u3044\u3066\u3082\u89e6\u308c\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6297\u539f\u539f\u7f6a\u3068\u3044\u3046\u306e\u306f\u3001\u6700\u521d\u306b\u611f\u67d3\u3057\u305f\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306e\u75c5\u539f\u4f53\u306e\u6297\u539f\u306b\u5bfe\u3057\u3066\u514d\u75ab\u304c\u7372\u5f97\u3055\u308c\u305f\u5f8c\u306b\u3001\u305d\u308c\u304c\u5237\u308a\u8fbc\u307e\u308c\u3001\u514d\u75ab\u7cfb\u304c\u305d\u306e\u8a18\u61b6\u306b\u56fa\u57f7\u3057\u3066\u3001\u5909\u7570\u3057\u305f\u6297\u539f\u306b\u5bfe\u3057\u3066\u306f\u6297\u4f53\u7523\u751f\u304c\u6291\u5236\u3055\u308c\u308b\u73fe\u8c61\u306e\u3053\u3068\u3067\u3059\u3002\u30ef\u30af\u30c1\u30f3\u306e\u5834\u5408\u3082\u540c\u69d8\u3068\u8003\u3048\u3089\u308c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u306f\u6b66\u6f22\u682a\u306b\u5bfe\u3057\u3066\u6700\u521d\u306b\u4f5c\u3089\u308c\u3001\u305d\u306e\u5f8c2\u4fa1\u306b\u306a\u3063\u3066\u3082\u6b66\u6f22\u7528\u306e\u3082\u306e\u304c\u5165\u3063\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u305a\u3063\u3068\u65b0\u578b\u30b3\u30ed\u30ca\u306e\u6700\u521d\u306e\u6b66\u6f22\u682a\u306b\u5bfe\u3059\u308b\u6297\u4f53\u3092\u4f5c\u308a\u7d9a\u3051\u3066\u3057\u307e\u3044\u3001\u5909\u7570\u682a\u306b\u306f\u5bfe\u5fdc\u304c\u3067\u304d\u306a\u304f\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3066\u3082\u73fe\u5728\u306e\u30aa\u30df\u30af\u30ed\u30f3\u682a\u306b\u306f\u7c21\u5358\u306b\u611f\u67d3\u3057\u3066\u3057\u307e\u3046\u3067\u3057\u3087\u3046\u3002\u3055\u3089\u306b\u3001IgG4\u304c\u5897\u52a0\u3057\u3066\u514d\u75ab\u6291\u5236\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u3067\u3001\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3064\u307b\u3069\u611f\u67d3\u3057\u3084\u3059\u304f\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u3055\u3089\u306b\u3053\u306e\u8ad6\u6587\u306e\u6700\u5f8c\u306b\u306f\u300c\u6570\u304b\u6708\u5f8c\u306b\u306f\u6d88\u5931\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u682a\u306emRNA\u3092\u542b\u3080\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3059\u308b\u3053\u3068\u3067\u3001\u5065\u5eb7\u306a\u82e5\u8005\u306e\u611f\u67d3\u3092\u3059\u3079\u3066\u4e88\u9632\u3057\u3088\u3046\u3068\u3059\u308b\u306e\u3092\u3084\u3081\u308b\u3079\u304d\u3060\u300d\u3068\u8b66\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3066\u611f\u67d3\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u3055\u3089\u306b\u9ad8\u9f62\u8005\u3067\u306f\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u8133\u6897\u585e\u3001\u80ba\u585e\u6813\u75c7\u3001\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u306a\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u4f55\u306e\u305f\u3081\u306e\u30ef\u30af\u30c1\u30f3\u3067\u3057\u3087\u3046\u304b\uff1f\u82e5\u3044\u4eba\u3082\u5fc3\u7b4b\u708e\u3092\u8d77\u3053\u3059\u3057\u3001\u672c\u5f53\u3067\u3042\u308c\u3070\u3082\u3046\u8ab0\u3082\u6253\u3064\u4eba\u304c\u3044\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5b89\u5168\u3060\u3001\u611f\u67d3\u4e88\u9632\u3060\u3001\u3068\u3044\u307e\u3060\u306b\u56fd\u3084\u5c02\u9580\u5bb6\u306f\u63a8\u5968\u3057\u7d9a\u3051\u307e\u3059\u3002\u672c\u6765\u306f\u3082\u3046\u3068\u3063\u304f\u306b\u4e2d\u6b62\u3055\u308c\u3066\u3044\u308b\u306f\u305a\u306e\u6bd2\u7269\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u5b8c\u5168\u306a\u56e0\u679c\u95a2\u4fc2\u304c\u308f\u304b\u308b\u306f\u305a\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u308f\u304b\u3063\u3066\u304b\u3089\u3067\u306f\u9045\u3044\u3057\u3001\u3082\u3046\u3059\u3067\u306b\u304b\u306a\u308a\u306e\u5371\u967a\u6027\u306e\u60c5\u5831\u306f\u51fa\u3066\u3044\u307e\u3059\u3002\u4e16\u754c\u5404\u5730\u3067\u8d85\u904e\u6b7b\u4ea1\u306e\u5897\u52a0\u3001\u51fa\u751f\u7387\u306e\u4f4e\u4e0b\u304c\u8d77\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>2022\u5e74\u306e\u590f\u306bLancet\u3067\u767a\u8868\u3055\u308c\u305f\u3001\u5229\u76ca\u76f8\u53cd\u306e\u3042\u308a\u305d\u3046\u3067\u90fd\u5408\u306e\u826f\u3055\u305d\u3046\u306a\u8ad6\u6587\u3067\u306f\u3001\u30ef\u30af\u30c1\u30f3\u306b\u3088\u3063\u30662000\u4e07\u4eba\u306e\u547d\u304c\u6551\u308f\u308c\u305f\u3068\u3057\u3066\u3044\u307e\u3059\u3002\uff08<a href=\"https:\/\/www.thelancet.com\/journals\/laninf\/article\/PIIS1473-3099(22)00320-6\/fulltext\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u3057\u304b\u3057\u3001\u305d\u306e\u53cd\u9762\u30ef\u30af\u30c1\u30f3\u30672100\u4e07\u4eba\u304c\u6b7b\u4ea1\u300119\u51045000\u4e07\u4eba\u304c\u4f55\u3089\u304b\u306e\u526f\u4f5c\u7528\u3084\u5f8c\u907a\u75c7\u3092\u8ca0\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u8a08\u7b97\u3082\u3042\u308a\u307e\u3059\u3002\uff08<a href=\"https:\/\/peterhalligan.substack.com\/p\/cumulative-and-calendar-year-snap\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u4ee5\u524d\u30ef\u30af\u30c1\u30f3\u304c\u5341\u5206\u306b\u8cb7\u3048\u306a\u3044\u3088\u3046\u306a\u8ca7\u3057\u3044\u30a2\u30d5\u30ea\u30ab\u306e\u56fd\u306b\u65b0\u578b\u30b3\u30ed\u30ca\u304c\u6d41\u884c\u3057\u305f\u3089\u975e\u5e38\u306b\u591a\u304f\u306e\u4eba\u304c\u72a0\u7272\u306b\u306a\u308b\u3068\u3044\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u5b9f\u969b\u306b\u306f\u305d\u306e\u9006\u3067\u3057\u305f\u3002\u30b3\u30ed\u30ca\u306e\u81f4\u6b7b\u7387\u304c\u6700\u3082\u4f4e\u3044\u56fd\u306f\u30ef\u30af\u30c1\u30f3\u3092\u307b\u3068\u3093\u3069\u63a5\u7a2e\u3057\u3066\u3044\u306a\u3044\u30a2\u30d5\u30ea\u30ab\u56fd\u3005\u3067\u3059\u3002<\/p>\n<p>\u56fd\u304c\u3084\u3081\u306a\u3044\u306e\u3067\u3042\u308c\u3070\u3001\u4efb\u610f\u63a5\u7a2e\u306a\u3093\u3067\u3059\u304b\u3089\u3001\u81ea\u5206\u3067\u3084\u3081\u308b\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002<span style=\"color: #ff0000;\">\u63a5\u7a2e\u3057\u3066\u5f97\u3089\u308c\u308b\u5229\u76ca\u306f\u4f55\u3082\u3042\u308a\u307e\u305b\u3093<\/span>\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #3366ff;\">\u300cSurveillance of COVID-19 vaccine safety among elderly persons aged 65 years and older\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c65\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308bCOVID-19\u30ef\u30af\u30c1\u30f3\u306e\u5b89\u5168\u6027\u306e\u8abf\u67fb\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36496287\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6628\u5e74\u672b\u304b\u3089\u4eca\u5e74\u306b\u5165\u3063\u3066\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u98a8\u5411\u304d\u304c\u5909\u308f\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u660e\u3089\u304b\u306b\u6709\u5bb3\u6027\u306a\u3069\u306e\u5831\u544a\u3001\u8a18\u4e8b\u304c\u5897\u52a0\u3057\u3066\u304d\u305f\u3088\u3046\u306b\u601d\u3048\u307e\u3059\u3002 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