{"id":2156,"date":"2017-08-01T19:03:18","date_gmt":"2017-08-01T10:03:18","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=2156"},"modified":"2020-01-10T08:41:37","modified_gmt":"2020-01-09T23:41:37","slug":"post-2156","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=2156","title":{"rendered":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u5024\u3060\u3051\u3067\u306f\u4f55\u3082\u308f\u304b\u3089\u306a\u3044"},"content":{"rendered":"

\u5148\u65e5\u3001\u8cea\u554f\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u306f\u3058\u3081\u307e\u3057\u3066\u3001\u5065\u5eb7\u8a3a\u65ad\u306e\u7d50\u679c\u3067\u82e6\u616e\u3057\u3066\u3044\u3068\u3053\u308d\u3001\u5148\u751f\u306e\u30d6\u30ed\u30b0\u3092\u62dd\u898b\u3044\u305f\u3057\u307e\u3057\u305f\u3002<\/span>
\n \u4f1a\u793e\u306e\u5065\u5eb7\u8a3a\u65ad\u3067LDL\u9ad8\u5024\uff08LDL 184\u3001HDL 65\u3001\u4e2d\u6027\u8102\u80aa\u300061\uff09\u3067\u8981\u53d7\u8a3a\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u5185\u79d1\u533b\u3044\u308f\u304f\u3001\u3044\u3064\u5fc3\u7b4b\u6897\u585e\u306b\u306a\u3063\u3066\u3082\u304a\u304b\u3057\u304f\u306a\u3044\u3001\u98df\u4e8b\u3067\u306f\u6539\u5584\u3057\u306a\u3044\u305f\u3081\u85ac\u3067\u4e0b\u3052\u308b\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3068\u8a00\u308f\u308c\u307e\u3057\u305f\u3002\u8840\u7ba1\u304c\u56fa\u304f\u8a70\u307e\u3063\u3066\u304a\u308a\u975e\u5e38\u306b\u5371\u967a\u306a\u72b6\u614b\u3067\u3042\u308b\u3068\u52d5\u8108\u786c\u5316\u304c\u9032\u3093\u3060\u5199\u771f\u7b49\u3092\u307f\u305b\u3089\u308c\u307e\u3057\u305f\u3002<\/span><\/p>\n

\u3059\u3054\u3044\u8105\u3057\u3067\u3059\u306d\u3002\u3073\u3063\u304f\u308a\u3057\u307e\u3057\u305f\u3002LDL\u304c\u9ad8\u3044\u3068\u3059\u3050\u306b\u5371\u967a\u3068\u3044\u3046\u5224\u65ad\u306b\u306a\u308b\u306e\u304c\u5f53\u305f\u308a\u524d\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/span><\/p>\n

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607<\/a>\u300d\u3067\u3082\u66f8\u304d\u307e\u3057\u305f\u304c\u3001LDL\u306f\u975e\u5e38\u306b\u4e0d\u78ba\u304b\u306a\u6570\u5024\u3067\u3059\u3002LDL\u306f\u6570\u5024\u3068\u3044\u3046\u3088\u308a\u3082\u8cea\u304c\u91cd\u8981\u3067\u3059\u3002\u305d\u308c\u306a\u306e\u306b\u3001\u3044\u307e\u3060\u306b\u533b\u5e2b\u306e\u4e2d\u3067\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1d\u60aa\u7389\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u3044\u3046\u8003\u3048\u304c\u629c\u3051\u307e\u305b\u3093\u3002\u4eba\u4f53\u306b\u60aa\u5f71\u97ff\u306a\u306e\u306fLDL\u306e\u4e2d\u3067\u3082\u5c0f\u7c92\u5b50\u9ad8\u5bc6\u5ea6LDL\u3067\u3059\u3002\u3053\u306e\u5c0f\u7c92\u5b50LDL\u306f\u9178\u5316LDL\u306b\u5909\u5316\u3057\u3084\u3059\u304f\u3001\u52d5\u8108\u786c\u5316\u306e\u539f\u56e0\u3001\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u304f\u3059\u308b\u3082\u306e\u306a\u306e\u3067\u3059\u3002\u5927\u304d\u306a\u7c92\u5b50\u306e\u3075\u308f\u3075\u308f\u3057\u305fLDL\u306f\u5168\u304f\u60aa\u7389\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u73fe\u5728\u306e\u8840\u6db2\u691c\u67fb\u3067\u306fLDL\u304c\u5927\u304d\u3044\u306e\u304b\u5c0f\u3055\u3044\u306e\u304b\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u305d\u3057\u3066\u3001\u3053\u308c\u3082\u4ee5\u524d\u306e\u8a18\u4e8b\u306b\u66f8\u304d\u307e\u3057\u305f\u304c\u3001\u901a\u5e38\u306f\u8a08\u7b97\u5f0f\u3067\u6c42\u3081\u308b\u63a8\u6e2c\u5024\u3067\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u4eca\u56de\u793a\u3059\u7814\u7a76\u3067\u306f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306f\u7121\u95a2\u4fc2\u306b\u3001LDL\u306e\u7c92\u5b50\u306e\u5927\u304d\u3055\u304c\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u30c7\u30fc\u30bf\u3067\u3059\u3002\u8105\u3057\u3092\u884c\u3063\u305f\u533b\u5e2b\u306f\u3053\u308c\u3092\u8aad\u3080\u3068\u3069\u3046\u601d\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

 <\/p>\n

\u300cSmall, Dense Low-Density Lipoprotein Particles as a Predictor of the Risk of Ischemic Heart Disease in Men\u300d<\/span><\/p>\n

\u300c\u7537\u6027\u306b\u304a\u3051\u308b\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306e\u4e88\u6e2c\u56e0\u5b50\u3068\u3057\u3066\u306e\u5c0f\u7c92\u5b50\u9ad8\u5bc6\u5ea6LDL\u7c92\u5b50\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u8981\u7d04<\/span><\/p>\n

\u865a\u8840\u6027\u5fc3\u75be\u60a3\u60a3\u8005\u306f\u3001\u5065\u5eb7\u306a\u4eba\u3088\u308a\u3082\u5c0f\u3055\u3044\u3001\u9ad8\u5bc6\u5ea6\u306eLDL\u7c92\u5b50\u306e\u5272\u5408\u304c\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u5c0f\u7c92\u5b50LDL\u306b\u8d77\u56e0\u3059\u308b\u30ea\u30b9\u30af\u306e\u7a0b\u5ea6\u306f\u8840\u6f3f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea – \u8102\u8cea\u6fc3\u5ea6\u306e\u5909\u52d5\u3068\u306f\u7121\u95a2\u4fc2\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u306f\u660e\u3089\u304b\u3067\u3042\u308b\u3002<\/span><\/p>\n

\u6700\u521d\u306b\u865a\u8840\u6027\u5fc3\u75be\u60a3\u304c\u306a\u30442103\u4eba\u306e\u7537\u6027\u3067\u30015\u5e74\u9593\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u306b114\u4eba\u306e\u865a\u8840\u6027\u5fc3\u75be\u60a3IHD\u3092\u767a\u75c7\u3057\u305f\u3002LDL\u7c92\u5b50\u306e\u30d4\u30fc\u30af\u306e\u7c92\u5f84\uff08PPD\uff09\u3092\u6e2c\u5b9a\u3057\u305f\u3002LDL-PPD\u5206\u5e03\uff08LDL-PPD\u226625.64nm\uff09\u306e\u7b2c1\u4e09\u5206\u4f4d\u306e\u4eba\u306f\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u3001\u7b2c3\u4e09\u5206\u4f4d\u306e\u4eba\uff08LDL-PPD> 26.05 nm\uff09\u3068\u6bd4\u8f03\u3057\u30663.6\u500d\u5897\u52a0\u3057\u305f\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u4e2d\u6027\u8102\u80aa\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30afB\u306e\u6fc3\u5ea6\u306f\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3068\u5c0f\u7c92\u5b50LDL\u306e\u95a2\u9023\u306b\u5f71\u97ff\u3057\u306a\u304b\u3063\u305f\u3002<\/span><\/p>\n

\u7d50\u8ad6\u3068\u3057\u3066\u3001\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u5c0f\u3055\u3044\u3001\u9ad8\u5bc6\u5ea6\u306eLDL\u7c92\u5b50\u306e\u5b58\u5728\u304c\u3001\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u6700\u521d\u306e\u524d\u5411\u304d\u306a\u8a3c\u62e0\u3067\u3042\u308b\u3002\u7d50\u679c\u306f\u307e\u305f\u3001\u5c0f\u3055\u306aLDL\u7c92\u5b50\u306b\u8d77\u56e0\u3059\u308b\u30ea\u30b9\u30af\u306f\u3001\u8840\u6f3f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af – \u8102\u8cea\u6fc3\u5ea6\u306e\u4ed8\u968f\u3059\u308b\u5909\u52d5\u3068\u90e8\u5206\u7684\u306b\u306f\u7121\u95a2\u4fc2\u3067\u3042\u308a\u5f97\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u3002<\/span><\/p>\n

 <\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\uff08\u30af\u30ea\u30c3\u30af\u3067\u62e1\u5927\u3001\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\u3053\u306e\u56f3\u306f\u6a2a\u8ef8\uff08X\u8ef8\uff09\u304cLDL\u306e\u30d4\u30fc\u30af\u306e\u7c92\u5f84\u3092\u3042\u3089\u308f\u3057\u3066\u3044\u307e\u3059\u3002\u7e26\u8ef8\uff08Y\u8ef8\uff09\u304c\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u8d77\u3053\u308a\u3084\u3059\u3055\u306e\u6bd4\u3092\u3042\u3089\u308f\u3057\u3001Z\u8ef8\u306f\u4e0a\u306e\u56f3\u304c\u30a2\u30dd\u30d7\u30ed\u30c6\u30a4\u30f3B\uff08ApoB\uff09\u306e\u6fc3\u5ea6\u3001\u4e0b\u306e\u56f3\u304c\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4\u3092\u3042\u3089\u308f\u3057\u3066\u3044\u307e\u3059\u3002\u30a2\u30dd\u30d7\u30ed\u30c6\u30a4\u30f3B\u306fApoB\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u904b\u3076\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u751f\u6210\u8a98\u767a\u306e\u6307\u6a19\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u3046\u3059\u308b\u3068\u3001LDL\u7c92\u5b50\u304c\u5927\u304d\u3044\u5834\u5408\u3001ApoB\u304c\u9ad8\u304f\u3066\u3082\u3001\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306f2\u500d\u7a0b\u5ea6\u3067\u3059\u304c\u3001LDL\u306e\u7c92\u5b50\u304c\u5c0f\u3055\u304f\u3066ApoB\u304c\u9ad8\u3044\u5834\u5408\u306f\u30ea\u30b9\u30af\u304c6.2\u500d\u306b\u8df3\u306d\u4e0a\u304c\u308a\u307e\u3059\u3002ApoB\u304c\u4f4e\u3044\u5834\u5408\u306fLDL\u306e\u7c92\u5b50\u306e\u5927\u304d\u3055\u3068\u306f\u95a2\u4fc2\u306a\u3044\u3088\u3046\u3067\u3059\u3002<\/p>\n

\u6b21\u306b\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4\u3067\u307f\u3066\u307f\u308b\u3068\u3001\u540c\u3058\u3088\u3046\u306bLDL\u306e\u7c92\u5b50\u304c\u5c0f\u3055\u304f\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4\u304c6\u4ee5\u4e0a\u306b\u306a\u308b\u3068\u30ea\u30b9\u30af\u304c4.9\u500d\u306b\u8df3\u306d\u4e0a\u304c\u308a\u307e\u3059\u3002<\/p>\n

\u8cea\u554f\u3055\u308c\u305f\u65b9\u306e\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f261\u3050\u3089\u3044\u3068\u63a8\u6e2c\u3055\u308c\u307e\u3059\u3057\u3001HDL\u306f65\u306a\u306e\u3067\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4\u306f4\u7a0b\u5ea6\u3067\u3059\u3002LDL\u306e\u7c92\u5b50\u5f84\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u3082\u3057\u3001\u5c0f\u3055\u304b\u3063\u305f\u3068\u3057\u3066\u30821.2\u500d\u7a0b\u5ea6\u306e\u30ea\u30b9\u30af\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3057\u3001HDL\u304c65\u3067\u4e2d\u6027\u8102\u80aa\u304c61\u306e\u5834\u5408\u3001TG\uff08\u4e2d\u6027\u8102\u80aa\uff09 \/ HDL-C\u6bd4\u306f0.94\u306a\u306e\u3067\u660e\u3089\u304b\u306bLDL\u7c92\u5b50\u306f\u5927\u304d\u306a\u3075\u308f\u3075\u308f\u826f\u8ceaLDL\u3067\u3057\u3087\u3046\u3002<\/p>\n

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