{"id":22113,"date":"2023-03-13T08:46:49","date_gmt":"2023-03-12T23:46:49","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=22113"},"modified":"2023-03-13T08:46:49","modified_gmt":"2023-03-12T23:46:49","slug":"sdldl%e3%81%8c%e9%ab%98%e3%81%84%e3%81%a8%e8%a8%80%e3%82%8f%e3%82%8c%e3%81%9f%e3%81%91%e3%82%8c%e3%81%a9","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=22113","title":{"rendered":"sdLDL\u304c\u9ad8\u3044\u3068\u8a00\u308f\u308c\u305f\u3051\u308c\u3069\u2026"},"content":{"rendered":"

LDL\u306e\u4e2d\u3067\u3082\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\u3067\u3042\u308bsdLDL\u306b\u3064\u3044\u3066\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u3093\u306b\u3061\u306f<\/span>
\n\u3044\u3064\u3082\u5148\u751f\u306e\u30d6\u30ed\u30b0\u3092\u697d\u3057\u307f\u306b\u3057\u3066\u304a\u308a\u307e\u3059\u300270\u624d\u5973\u6027\u3067\u3059\u3002<\/span>
\n\u79c1\u306f\u7cd6\u5c3f\u75c5\u767a\u899a1\u5e74\u5f8c\u306e2015\u5e74\u304b\u3089\u59cb\u3081\u305f\u7cd6\u8cea\u5236\u9650\u3067\u3001A1c\u306f6.2\u7a0b\u5ea6\u3068\u306a\u308a\u307e\u3057\u305f\u3002 \u7cd6\u8cea\u5236\u9650\u524d\u306f\u57fa\u6e96\u5024\u3060\u3063\u305f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001\u7cd6\u8cea\u5236\u9650\u958b\u59cb\u5f8c\u306b\u306fLDL250\u301c300\u3001HDL130\u301c150\u3068\u3069\u3093\u3069\u3093\u4e0a\u6607\u3057\u305f\u307e\u307e\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306f30\u301c40(\u56e0\u307f\u306b\u4f53\u8102\u80aa\u738716.5%)\u3068\u4f4e\u5024\u5b89\u5b9a<\/span>
\n\u5148\u751f\u306e\u30d6\u30ed\u30b0\u3092\u983c\u308a\u306b\u3001\u904b\u52d5\u3092\u3088\u304f\u3059\u308b\u7cd6\u8cea\u5236\u9650\u8005\u306b\u306f\u3042\u308a\u5f97\u308b\u4e8b\u3068\u697d\u89b3\u306f\u3057\u3066\u304a\u308a\u307e\u3057\u305f\u304c\u3001\u4fdd\u5065\u6240\u3082\u7169\u304f\u554f\u3044\u5408\u308f\u305b\u3066\u6765\u307e\u3059\u3057\u3001\u81ea\u5206\u3067\u3082\u77e5\u308a\u305f\u3044\u3068\u601d\u3044\u3001\u672c\u5f53\u306b\u6016\u3044\u3068\u8a00\u3046sdLDL\u3092\u691c\u67fb\u3057\u3066\u8cb0\u3044\u307e\u3057\u305f\u3002\u3059\u308b\u3068\u7121\u3044\u7b48\u3068\u601d\u3063\u3066\u3044\u305f\u6570\u5024\u306f88mg\\ DL\u3068\u8981\u6cbb\u7642\u5024\u3067\u3057\u305f\u3002\u305d\u3053\u304b\u30891\u5e74\u9593\u30b9\u30bf\u30c1\u30f3\u3092\u53d7\u3051\u5165\u308c\u307e\u3057\u305f\u304c\u3001<\/span>
\n\u305f\u3044\u3057\u305f\u6570\u5024\u306e\u5909\u5316\u306f\u7121\u304f\u3001\u53cd\u5bfe\u306b\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3a1c\u304c0.3\u4e0a\u6607\u3002\u30b9\u30bf\u30c1\u30f3\u670d\u7528\u4e2d\u306f\u80c3\u8178\u306e\u8abf\u5b50\u304c\u60aa\u304b\u3063\u305f\u304d\u304c\u3057\u307e\u3059\u3002<\/span>
\n\u305d\u3053\u3067\u3001\u60a9\u307e\u3057\u3044\u306e\u304c\u5909\u308f\u3089\u305a\u9ad8\u5024\u306esd LDL\u3067\u3059\u3002\u3057\u304b\u3057\u73fe\u5728\u3082\u3068\u3066\u3082\u5143\u6c17\u3001\u903112\u6642\u9593\u306e\u6b66\u9053\u3084\u30b8\u30e0\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u52b1\u3093\u3067\u3044\u307e\u3059\u3002\u6570\u5024\u3070\u304b\u308a\u6c17\u306b\u3057\u3066\u85ac\u98f2\u3080\u3088\u308a\u3001\u60aa\u7389\u3068\u8a00\u308f\u308c\u3066\u3044\u308bSDLDL\u3055\u3048\u79c1\u306b\u3068\u3063\u3066\u306f\u5fc5\u8981\u306a\u5c0f\u578b\u30bf\u30a4\u30d7\u306a\u306e\u304b\u3082\u77e5\u308c\u306a\u3044\u3068\u958b\u304d\u76f4\u308b\u4e8b\u306b\u3057\u307e\u3057\u305f\u3002\u305f\u3060\u3001\u4eca\u5e74\u306e\u691c\u8a3a\u304b\u3089\u981a\u52d5\u8108\u30d7\u30e9\u30fc\u30af\u306e\u30a8\u30b3\u30fc\u691c\u67fb\u3092\u8ffd\u52a0\u30aa\u30fc\u30c0\u30fc\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/span>
\nSDLDL\u306b\u3064\u3044\u3066\u306e\u304a\u8003\u3048\u3092\u4f3a\u3048\u308c\u3070\u5e78\u3044\u3067\u3059\u3002\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3057\u307e\u3059\u3002<\/span><\/p>\n

sdLDL\u3092\u6e2c\u5b9a\u3057\u3066\u4e0d\u5b89\u306b\u306a\u3063\u3066\u3044\u308b\u65b9\u306f\u610f\u5916\u3068\u591a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u307e\u305a\u3001\u52d8\u9055\u3044\u3055\u308c\u306a\u3044\u3088\u3046\u306b\u6700\u521d\u306b\u66f8\u3044\u3066\u304a\u304d\u307e\u3059\u304c\u3001\u4e2d\u6027\u8102\u80aa\u5024\u304c\u975e\u5e38\u306b\u4f4e\u304f\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u975e\u5e38\u306b\u9ad8\u304f\u3066\u3082sdLDL\u306f\u7686\u7121\u3001\u30bc\u30ed\u3067\u306f\u6c7a\u3057\u3066\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u79c1\u306e\u5834\u5408\u3067\u306fsdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f12mg\/dL\u3001\u5168\u4f53\u306e4\uff05\u3067\u3057\u305f\u3002\uff08\u300c\u79c1\u306e\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\u306f\u3069\u308c\u304f\u3089\u3044\u3042\u308b\u304b\uff1f<\/a>\u300d\u53c2\u7167\uff09LDL\u306e\u5927\u534a\u304c\u3075\u308f\u3075\u308f\u3057\u305f\u5927\u304d\u306aLDL\u3067\u3042\u308b\u3060\u3051\u3067\u3001\u5c0f\u3055\u3044sdLDL\u304c0\uff05\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u3082\u3046\u4e00\u3064\u3001sdLDL\u306f\u5c0f\u3055\u3044\u304b\u3089\u8840\u7ba1\u58c1\u3092\u901a\u308a\u629c\u3051\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002LDL\u3068sdLDL\u306e\u5927\u304d\u3055\u306e\u5dee\u306f\u305b\u3044\u305c\u3044\u6570nm\u3068\u3044\u3046\u30ec\u30d9\u30eb\u3067\u3059\u3002sdLDL\u306f\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308a\u3001\u6050\u3089\u304f\u305d\u306e\u3082\u306e\u304c\u5371\u967a\u3067\u306f\u306a\u304f\u3001\u305d\u308c\u304c\u9ad8\u3044\u5024\u307e\u305f\u306f\u9ad8\u3044\u5272\u5408\u306e\u72b6\u614b\u3092\u4f5c\u308a\u51fa\u3059\u4f53\u306e\u7570\u5e38\u304c\u30a2\u30c6\u30ed\u30fc\u30e0\u3092\u4f5c\u308a\u51fa\u3059\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u666e\u901a\u306eLDL\u3082sdLDL\u3082\u8840\u7ba1\u58c1\u306b\u9699\u9593\u304c\u958b\u3044\u3066\u3044\u3066\u3001\u305d\u3053\u3092\u81ea\u7531\u306b\u901a\u308a\u629c\u3051\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u305d\u3093\u306a\u9699\u9593\u304c\u3042\u3063\u305f\u3089\u8840\u6db2\u81ea\u4f53\u304c\u8840\u7ba1\u5916\u306b\u6f0f\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u666e\u901a\u306b\u8003\u3048\u308c\u3070\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u3066\u8840\u7ba1\u5185\u304b\u3089\u5165\u308a\u8fbc\u3093\u3067\u3044\u304f\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u3055\u3066\u73fe\u5728\u306e\u3068\u3053\u308dsdLDL\u306e\u6e2c\u5b9a\u6cd5\u306f\u3044\u308d\u3044\u308d\u3042\u308a\u307e\u3059\u304c\u3001\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u306a\u6e2c\u5b9a\u6cd5\u306f\u6c7a\u3081\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u6e2c\u5b9a\u6cd5\u304c\u9055\u3048\u3070\u3001\u6570\u5024\u3082\u7570\u306a\u308a\u307e\u3059\u3002\u307e\u3060\u307e\u3060\u3061\u3083\u3093\u3068\u3057\u305f\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9\u304c\u306a\u3044\u306e\u304c\u73fe\u72b6\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u3093\u306a\u4e2d\u4eca\u73fe\u5728\u4e00\u756a\u884c\u308f\u308c\u3066\u3044\u308b\u306e\u306f\u3001\u30c7\u30f3\u30ab\u793e\u306esdLDL\u691c\u67fb\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u3053\u308c\u306fLDL\u306e\u5927\u304d\u3055\u3092\u6e2c\u5b9a\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u6bd4\u91cd\u3092\u6e2c\u5b9a\u3057\u3066\u3044\u308b\u306f\u305a\u3067\u3059\u3002\u5c0f\u3055\u306aLDL\u3067\u3042\u308bsdLDL\u3060\u3051\u3067\u306a\u304f\u3001\u7d50\u69cb\u306a\u5272\u5408\u306eLDL\u3092\u542b\u3093\u3067\u3057\u307e\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3053\u308c\u306fsdLDL\u306e\u5b9a\u7fa9\u304c\u5b9a\u307e\u3063\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u304c\u4e00\u756a\u306e\u554f\u984c\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3044\u307e\u3059\u3002sdLDL\u306fsmall\uff08\u5c0f\u3055\u3044\uff09dense\uff08\u9ad8\u5bc6\u5ea6\uff09\u306eLDL\u3067\u3001\u5c0f\u3055\u3044\u306e\u3092sdLDL\u3068\u3059\u308b\u306e\u304b\u3001\u9ad8\u5bc6\u5ea6\u306e\u3082\u306e\u3092sdLDL\u3068\u3059\u308b\u306e\u304b\u3001\u3068\u3044\u3046\u9055\u3044\u304c\u3042\u308b\u3068\u8a00\u3048\u307e\u3059\u3002\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u304c\u6c7a\u3081\u3089\u308c\u306a\u3044\u307e\u307e\u3001\u6e2c\u5b9a\u3060\u3051\u304c\u884c\u308f\u308c\u3066\u3044\u3066\u3001\u305d\u308c\u3092\u3069\u3046\u6271\u3046\u304b\u3082\u4e00\u81f4\u3057\u3066\u306f\u3044\u306a\u3044\u72b6\u614b\u3067\u3059\u3002<\/p>\n

\u73fe\u5728\u30c7\u30f3\u30ab\u793e\u306fsdLDL\u6e2c\u5b9a\u306b\u529b\u3092\u5165\u308c\u3066\u3044\u308b\u306e\u304b\u3001\u591a\u304f\u306e\u7814\u7a76\u306b\u8cc7\u91d1\u3092\u51fa\u3057\u3066\u3044\u307e\u3059\u3002\u81ea\u5206\u306e\u4f01\u696d\u306e\u6e2c\u5b9a\u6cd5\u304c\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u306b\u306a\u308b\u305f\u3081\u306b\u30a8\u30d3\u30c7\u30f3\u30b9\u4f5c\u308a\u3092\u3057\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u3002\u305d\u3057\u3066\u3001\u5b66\u4f1a\u306e\u304a\u5049\u3044\u65b9\u306a\u3069\u304c\u30bb\u30fc\u30eb\u30b9\u30de\u30f3\u3068\u306a\u308a\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u3053\u306e\u6e2c\u5b9a\u6cd5\u304c\u6700\u3082\u4e00\u822c\u7684\u306a\u65b9\u6cd5\u3067\u3001\u4fe1\u983c\u3067\u304d\u308b\u3068\u8f09\u3063\u3066\u3057\u307e\u3048\u3070\u3001\u975e\u5e38\u306b\u4f01\u696d\u306e\u5229\u76ca\u306f\u4e0a\u304c\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u3082\u3061\u308d\u3093\u3001\u3053\u306e\u3088\u3046\u306a\u8003\u3048\u306f\u79c1\u306e\u63a8\u6e2c\u306b\u3059\u304e\u307e\u305b\u3093\u304c\u3001\u305d\u3093\u306a\u306b\u9593\u9055\u3063\u3066\u306f\u3044\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u3093\u306a\u4f01\u696d\u3084\u533b\u7642\u5074\u306e\u601d\u60d1\u3092\u77e5\u3089\u306a\u3044\u307e\u307e\u3001\u4e00\u822c\u306e\u4eba\u306f\u691c\u67fb\u3092\u53d7\u3051\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u308c\u3067\u3082\u5168\u304f\u610f\u5473\u306e\u306a\u3044\u691c\u67fb\u3067\u306f\u306a\u3044\u306e\u3067\u3001\u3061\u3087\u3063\u3068\u3044\u304f\u3064\u304b\u306e\u306a\u8ad6\u6587\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n

\u307e\u305a\u306f\u3001sdLDL\u3068\u305d\u308c\u4ee5\u5916\u306e\u6e2c\u5b9a\u5024\u3068\u306e\u95a2\u9023\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\u4e0b\u306e\u56f3\u306e\u6a2a\u8ef8\u306fsdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3001\u7e26\u8ef8\u306f(a)\u304b\u3089\u9806\u306b\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u76f4\u63a5\u6e2c\u5b9aLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u8a08\u7b97\u6cd5\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u5927\u304d\u306a\u6bd4\u91cd\u306e\u8efd\u3044LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001LDL\u306e\u4e2d\u6027\u8102\u80aa\u3001VLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u975eHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001HDL3\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001HDL2\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u4e2d\u6027\u8102\u80aa\u3001\u30a2\u30c7\u30a3\u30dd\u30cd\u30af\u30c1\u30f3\u3001Lp(a)\u3001CRP\u3067\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\u4e00\u822c\u7684\u306b\u6e2c\u5b9a\u3057\u306a\u3044\u3082\u306e\u306f\u7f6e\u3044\u3068\u3044\u3066\u3001\u30d1\u30c3\u3068\u898b\u3066sdLDL\u306fLDL\u3084\u4e2d\u6027\u8102\u80aa\u3001VLDL\u306a\u3069\u3068\u306f\u6bd4\u4f8b\u95a2\u4fc2\u3001HDL\u3068\u306f\u53cd\u6bd4\u4f8b\u306e\u95a2\u4fc2\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u5b9f\u306f\u5927\u304d\u306a\u6bd4\u91cd\u306e\u8efd\u3044LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08\u8cea\u306e\u826f\u3044LDL\uff09\u3055\u3048sdLDL\u3068\u6bd4\u4f8b\u95a2\u4fc2\u306b\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001LDL\u4ee5\u5916\u3069\u308c\u3082\u304b\u306a\u308a\u306e\u3070\u3089\u3064\u304d\u3067\u3059\u3002\u3067\u306f\u3001\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u3044\u305f\u5973\u6027\u306eLDL\u3092300\u3001HDL\u3092150\u3001\u4e2d\u6027\u8102\u80aa\u309230\u3068\u8003\u3048\u3066\u3001sdLDL88\u3068\u306e\u4ea4\u70b9\u3092\u898b\u3066\u304f\u3060\u3055\u3044\u3002\u5b8c\u5168\u306b\u5916\u308c\u5024\u3067\u3059\u3002\u5916\u308c\u5024\u3068\u306f\u4ed6\u306e\u5024\u304b\u3089\u5927\u304d\u304f\u5916\u308c\u305f\u5024\u3067\u3001\u4e00\u822c\u7684\u306a\u4eba\u304b\u3089\u8003\u3048\u305f\u3089\u307e\u305a\u306f\u3042\u308a\u5f97\u306a\u3044\u6570\u5024\u306a\u306e\u3067\u3059\u3002\u3055\u3066\u3001\u3053\u3053\u3067\u4e00\u822c\u7684\u306a\u4eba\u3068\u3044\u3046\u306e\u306f\u5f53\u7136\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3057\u3066\u3044\u308b\u4eba\u3067\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3057\u3066\u3044\u308b\u4eba\u306e\u30c7\u30fc\u30bf\u306b\u7cd6\u8cea\u5236\u9650\u306e\u4eba\u306e\u30c7\u30fc\u30bf\u3092\u5f53\u3066\u306f\u3081\u3066\u3082\u4f55\u3082\u308f\u304b\u3089\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u79c1\u3082\u3044\u304f\u3064\u3082\u306e\u8a18\u4e8b\u3067\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u8005\u306e\u7814\u7a76\u3092\u53d6\u308a\u4e0a\u3052\u3066\u3001\u305d\u308c\u3092\u7cd6\u8cea\u5236\u9650\u306b\u5f53\u3066\u306f\u3081\u308b\u3053\u3068\u306f\u3084\u3063\u3066\u3057\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u308c\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u4e2d\u3067\u3082\u79c1\u304c\u8003\u3048\u308b\u4e2d\u3067\u3001\u6050\u3089\u304f\u5065\u5eb7\u7684\u3001\u6709\u76ca\u3060\u3068\u601d\u3046\u30c7\u30fc\u30bf\u306b\u5bfe\u3057\u3066\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308c\u3070\u7c21\u5358\u306b\u305d\u306e\u6570\u5024\u3092\u9054\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u5f53\u3066\u306f\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u5225\u306e\u7814\u7a76\u3067\u306f\u3001\u4e2d\u6027\u8102\u80aa\u304c\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u3001sdLDL\u304c\u307b\u3068\u3093\u3069\u30a4\u30b3\u30fc\u30eb\u306e\u30ea\u30b9\u30af\u306b\u306a\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u56f3\u306f\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u5bfe\u7167\u7fa4\u306e\u30b5\u30d6\u30b3\u30db\u30fc\u30c8\u3068\u500b\u3005\u306e\u5fc3\u8840\u7ba1\u8ee2\u5e30\u306b\u304a\u3051\u308b\u88ab\u9a13\u8005\u306e\u4e2d\u6027\u8102\u80aa\u306e\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08\u3044\u308f\u3086\u308b\u30ec\u30e0\u30ca\u30f3\u30c8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\uff08\u5de6\uff09\u304a\u3088\u3073sdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb \uff08\u53f3\uff09\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6fc3\u5ea6\u3067\u3059\u3002\u3002IS\uff1a\u865a\u8840\u6027\u8133\u5352\u4e2d\u3001MI\uff1a\u5fc3\u7b4b\u6897\u585e\u3001PAD\uff1a\u672b\u68a2\u52d5\u8108\u75be\u60a3\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306e\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304a\u3088\u3073sdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u30b5\u30d6\u30b3\u30db\u30fc\u30c8\u3068\u6bd4\u8f03\u3057\u3066\u5404\u75c7\u4f8b\u7fa4\u3067\u6709\u610f\u306b\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u5fc3\u7b4b\u6897\u585e\u306esdLDL\u306f\u5bfe\u7167\u7fa4\u3088\u308a10\u4ee5\u4e0a\u9ad8\u3044\u3067\u3059\u304c\u3001\u865a\u8840\u6027\u8133\u5352\u4e2d\u3084\u672b\u68a2\u52d5\u8108\u75be\u60a3\u3067\u306f10\u672a\u6e80\u306e\u9055\u3044\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u304c\u672c\u5f53\u306b\u610f\u5473\u306e\u3042\u308b\u9055\u3044\u306a\u306e\u304b\u306f\u7591\u554f\u3067\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u4e2d\u6027\u8102\u80aa\u306e\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304a\u3088\u3073sdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30924\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\u3066\u305d\u306e\u4e00\u756a\u5927\u304d\u306a\u30b0\u30eb\u30fc\u30d7\u3068\u4e00\u756a\u5c0f\u3055\u306a\u30b0\u30eb\u30fc\u30d7\u306e\u30ea\u30b9\u30af\u6bd4\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u4e00\u756a\u4e0a\u304b\u3089\u5fc3\u8840\u7ba1\u75be\u60a3\u5168\u4f53\u3001\u51a0\u52d5\u8108\u75be\u60a3\u304a\u3088\u3073\u8133\u8840\u7ba1\u75be\u60a3\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u672b\u68a2\u52d5\u8108\u75be\u60a3\u3001\u865a\u8840\u6027\u8133\u5352\u4e2d\u3067\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306e\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304a\u3088\u3073sdLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3067\u306f\u540c\u3058\u3088\u3046\u306a\u56f3\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u9ad8\u4e2d\u6027\u8102\u80aa\u8840\u75c7\u306f\u4e3b\u306bVLDL\u5897\u52a0\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u809d\u81d3\u3067\u306f\u5927\u578b\u3067\u4e2d\u6027\u8102\u80aa\u306b\u5bcc\u3080VLDL1\u3068\u5c0f\u578b\u306eVDLD2\u304c\u7523\u751f\u3001\u5206\u6ccc\u3055\u308c\u307e\u3059\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3067\u306fVLDL1\u306e\u5206\u6ccc\u306e\u307f\u304c\u4fc3\u9032\u3057\u307e\u3059\u3002\u3055\u3089\u306bApoC\u2162\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3084\u9ad8\u8840\u7cd6\u3067\u5897\u52a0\u3057\u3001VLDL\u306e\u7570\u5316\u969c\u5bb3\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002VLDL1\u304b\u3089sdLDL\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002\u3060\u304b\u3089\u3001\u4e2d\u6027\u8102\u80aa\u304c\u8c4a\u5bcc\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u3001sdLDL\u304c\u30ea\u30b9\u30af\u3068\u3057\u3066\u307b\u3068\u3093\u3069\u30a4\u30b3\u30fc\u30eb\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u9006\u306b\u8003\u3048\u308b\u3068\u4e2d\u6027\u8102\u80aa\u5024\u304c\u5341\u5206\u306b\u4f4e\u3044\u5834\u5408sdLDL\u306f\u4f4e\u304f\u306a\u3051\u308c\u3070\u304a\u304b\u3057\u3044\u306e\u3067\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u3053\u306e\u30c7\u30f3\u30ab\u793e\u306e\u691c\u67fb\u306e\u7cbe\u5ea6\u304c\u672c\u5f53\u306b\u81e8\u5e8a\u7684\u306b\u8a55\u4fa1\u3059\u308b\u306e\u306b\u5024\u3059\u308b\u306e\u304b\u7591\u554f\u3092\u6301\u3063\u3066\u3057\u307e\u3046\u308f\u3051\u3067\u3059\u3002<\/p>\n

sdLDL\u306e\u672c\u5f53\u306e\u610f\u5473\u3067\u306e\u8a55\u4fa1\u306f\u96e3\u3057\u3044\u3067\u3057\u3087\u3046\u3002\u3082\u3061\u308d\u3093\u3001sdLDL\u306f\u6050\u3089\u304f\u9178\u5316\u3001\u7cd6\u5316\u3057\u3084\u3059\u304f\u3001\u305d\u308c\u304c\u591a\u3044\u72b6\u614b\u3067\u306f\u708e\u75c7\u304c\u8d77\u304d\u3084\u3059\u304b\u3063\u305f\u308a\u3001\u8840\u6813\u304c\u3067\u304d\u3084\u3059\u304b\u3063\u305f\u308a\u30a2\u30c6\u30ed\u30fc\u30e0\u306e\u8981\u7d20\u306b\u306a\u3063\u305f\u308a\u3057\u3084\u3059\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n

sdLDL\u3092\u6e2c\u5b9a\u3059\u308b\u306e\u306f\u307e\u3060\u307e\u3060\u4e00\u822c\u7684\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3060\u304b\u3089\u3053\u305d\u30c7\u30f3\u30ab\u793e\u304c\u72d9\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u3002\u901a\u5e38\u306e\u6e2c\u5b9a\u5024\u3067\u304a\u304a\u3088\u305d\u306e\u4e88\u6e2c\u3092\u3059\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\u306e\u5272\u5408\u3092\u63a8\u6e2c\u3059\u308b\u306b\u306f\uff1f<\/a>\u300d\u304c\u53c2\u8003\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u4e2d\u6027\u8102\u80aa\u304c70\u4ee5\u4e0b\u3067\u3042\u308c\u307090.9%\u304c\u300c\u4e3b\u306b\u300d\u5927\u304d\u306a\u7c92\u5b50\u306eLDL\u3092\u6301\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u4e00\u65b9\u3001\u4e2d\u6027\u8102\u80aa\u304c200\u3092\u8d85\u3048\u308b\u3088\u3046\u3060\u3068\u300184.8%\u304c\u300c\u4e3b\u306b\u300dsdLDL\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3067\u3082\u4f55\u30d1\u30fc\u30bb\u30f3\u30c8\u304csdLDL\u304b\u308f\u304b\u308a\u307e\u305b\u3093\u3002LDL\u306e\u7c92\u5b50\u306f\u5927\u304d\u3044\u304b\u5c0f\u3055\u3044\u304b\u306e2\u629e\u3067\u306f\u306a\u304f\u3001\u30b0\u30e9\u30c7\u30fc\u30b7\u30e7\u30f3\u306b\u306a\u3063\u3066\u3044\u3066\u3001\u69d8\u3005\u306a\u30b5\u30a4\u30ba\u304c\u5171\u5b58\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u69d8\u3005\u306a\u7814\u7a76\u304b\u3089\u5f97\u3089\u308c\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u7cd6\u8cea\u5236\u9650\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u4ee5\u5916\u306f\u3059\u3079\u3066\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u72b6\u614b\u3067\u306e\u30c7\u30fc\u30bf\u3067\u3059\u3002\u307e\u305f\u69d8\u3005\u306a\u691c\u67fb\u5024\u306e\u57fa\u6e96\u5024\u3001\u6b63\u5e38\u5024\u306f\u3059\u3079\u3066\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u8005\u306e\u57fa\u6e96\u5024\u3001\u6b63\u5e38\u5024\u3067\u3059\u3002\u7cd6\u8cea\u5236\u9650\u306e\u57fa\u6e96\u5024\u306f\u307e\u3060\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u975e\u5e38\u306b\u591a\u304f\u306e\u4eba\u304c\u4f4e\u4e2d\u6027\u8102\u80aa\u3001\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3067\u3059\u3002\uff08\u300c\u9a5a\u304d\u306e\u7d50\u679c\uff01\u7cd6\u8cea\u5236\u9650\u306b\u304a\u3051\u308bHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u4e2d\u6027\u8102\u80aa\u3000\u307f\u306a\u3055\u3093\u306e\u8840\u6db2\u30c7\u30fc\u30bf\u304b\u3089\u3000\u305d\u306e2<\/a>\u300d\u300c\u307f\u306a\u3055\u3093\u306e\u8840\u6db2\u691c\u67fb\u30c7\u30fc\u30bf2020\u3000\u96c6\u8a08\u3000\u305d\u306e4\u3000HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/a>\u300d\u300c\u305d\u306e5\u3000\u4e2d\u6027\u8102\u80aa<\/a>\u300d\u300c\u305d\u306e6\u3000\u4e2d\u6027\u8102\u80aa\/HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u6bd4<\/a>\u300d\u53c2\u7167\uff09LDL\u306f\u6c17\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3057\u3001\u305d\u306e\u4e2d\u3067\u3082sdLDL\u306f\u3082\u3063\u3068\u6c17\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u533b\u7642\u306e\u4e16\u754c\u306f\u3044\u307e\u3060\u306b\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u304c\u6a19\u6e96\u3067\u3042\u308a\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3068\u4f55\u304c\u3069\u3046\u5909\u308f\u308b\u304b\u3001\u81ea\u5206\u3067\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3044\u308b\u4eba\u4ee5\u5916\u306f\u307b\u3068\u3093\u3069\u306e\u533b\u5e2b\u306f\u77e5\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u6e2c\u5b9a\u3057\u3066\u3082\u305d\u306e\u8a55\u4fa1\u3082\u96e3\u3057\u304f\u3001\u3069\u3046\u3059\u308c\u3070\u3044\u3044\u306e\u304b\u308f\u304b\u3089\u306a\u3044\u691c\u67fb\u306f\u3001\u305f\u3060\u4e0d\u5b89\u306b\u306a\u308b\u3060\u3051\u3067\u4f55\u3082\u6709\u76ca\u306a\u3053\u3068\u306f\u306a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u79c1\u306f\u30b9\u30bf\u30c1\u30f3\u306f\u5168\u304f\u4e0d\u8981\u3060\u3068\u8003\u3048\u307e\u3059\u3002\u3068\u3044\u3046\u3088\u308a\u7cd6\u8cea\u5236\u9650\u306b\u30b9\u30bf\u30c1\u30f3\u306f\u5371\u967a\u3060\u3068\u601d\u3044\u307e\u3059\u3002\uff08\u300c\u7cd6\u8cea\u5236\u9650\u306b\u30b9\u30bf\u30c1\u30f3\u306e\u4f75\u7528\u306f\u5371\u967a\u3067\u306f\u306a\u3044\u304b\uff1f<\/a>\u300d\u53c2\u7167\uff09\u305d\u3057\u3066\u3001\u73fe\u5728\u306e\u30c7\u30f3\u30ab\u793e\u306esdLDL\u691c\u67fb\u3082\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3044\u308b\u72b6\u614b\u3067\u306f\u3042\u307e\u308a\u610f\u5473\u304c\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u7b54\u3048\u306b\u306a\u308a\u307e\u3057\u305f\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

 <\/p>\n

\u300cSmall Dense Low-Density Lipoprotein Cholesterol and Carotid Intimal Medial Thickness Progression\u300d<\/span><\/p>\n

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