{"id":22173,"date":"2023-03-17T08:26:13","date_gmt":"2023-03-16T23:26:13","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=22173"},"modified":"2023-03-17T08:26:13","modified_gmt":"2023-03-16T23:26:13","slug":"%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%ab%e3%82%88%e3%82%8b%e3%82%b9%e3%83%91%e3%82%a4%e3%82%af%e3%82%bf%e3%83%b3%e3%83%91%e3%82%af%e3%81%af%e5%a4%a7","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=22173","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306b\u3088\u308b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306f\u5927\u91cf\u306b\u9577\u671f\u306b\u6e21\u308a\u4f53\u4e2d\u3092\u99c6\u3051\u5de1\u3063\u3066\u3044\u308b"},"content":{"rendered":"

\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u306e\u63a5\u7a2e\u304c\u59cb\u307e\u308b\u3053\u308d\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3067\u3067\u304d\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306f\u3059\u3050\u306b\u4f53\u304b\u3089\u6d88\u3048\u3001\u6297\u4f53\u3060\u3051\u304c\u6b8b\u308b\u3068\u805e\u3044\u305f\u899a\u3048\u306f\u3042\u308a\u307e\u305b\u3093\u304b\uff1f<\/p>\n

\u3067\u3082\u3001\u4e8b\u5b9f\u306f\u305d\u3046\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30a2\u30e1\u30ea\u30ab\u306e\u5c0f\u5150\u75c5\u9662\u306b\u5fc3\u7b4b\u708e\u3067\u5165\u9662\u3057\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u5fc3\u7b4b\u30c8\u30ed\u30dd\u30cb\u30f3 T \u306e\u4e0a\u6607\u3092\u4f34\u3046\u80f8\u75db\u3092\u5448\u3057\u305f 16 \u4eba\u306e\u60a3\u8005\u304b\u3089\u8840\u6db2\u3092\u63a1\u53d6\u3057\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306eA\u306f\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3055\u308c\u305f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304a\u3088\u3073\u5fc3\u7b4b\u708e\u306e\u8840\u6f3f\u3067\u6e2c\u5b9a\u3055\u308c\u305f\u904a\u96e2\u304a\u3088\u3073\u7dcfS1 \u304a\u3088\u3073\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u3067\u3059\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u306f\u6297\u4f53\u3068\u7d50\u5408\u3057\u3066\u3044\u306a\u3044\u904a\u96e2\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306f\u307b\u3068\u3093\u3069\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u304c\u3001\u5fc3\u7b4b\u708e\u306e\u8840\u6f3f\u3067\u306f\u6297\u4f53\u306b\u7d50\u5408\u3057\u3066\u3044\u306a\u3044\u5168\u9577\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304c\u304b\u306a\u308a\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u5e73\u5747\u3067\u7d0434pg\/mL\u3067\u3057\u305f\u3002<\/p>\n

\u56f3\u306eB\u306f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u65e5\u6570\u3068\u691c\u51fa\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306b\u3064\u3044\u3066\u3067\u3059\u3002\u4f55\u4eba\u304b\u306e\u5fc3\u7b4b\u708e\u3067\u306f20\u65e5\u3092\u904e\u304e\u3066\u3082\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304c\u8840\u4e2d\u306b\u6f02\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n

34pg\/mL\u3063\u3066\u3088\u304f\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u5168\u9577\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306e\u5206\u5b50\u91cf\u306f\u7d04150kDa\u3068\u304b180kDa\u3068\u304b\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u7d30\u304b\u3044\u3053\u3068\u306f\u79c1\u306b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n

150 \u30ad\u30ed\u30c9\u30eb\u30c8\u30f3 [kDa]= 2.490 808 381 5\u00d710-19<\/sup> \u30b0\u30e9\u30e0 [g]<\/p>\n

180 \u30ad\u30ed\u30c9\u30eb\u30c8\u30f3 [kDa]= 2.988 970 057 8\u00d710-19<\/sup> \u30b0\u30e9\u30e0 [g]<\/p>\n

\u3067\u3059\u3002\uff08\u8a08\u7b97\u306f\u3053\u3053<\/a>\uff09<\/p>\n

60kg\u306e\u4f53\u91cd\u3060\u3068\u8840\u6f3f\u91cf\u306f\u305d\u306e\u7d045\uff05\u3067\u30013000ml\u3067\u3059\u300234pg\/ml\u00d73000ml \uff1d102,000pg\uff1d102\u00d710-9<\/sup>g<\/p>\n

\u306a\u306e\u3067\u3001150\uff5e180kDa\u3067\u5272\u308b\u3068\u30013400\uff5e4000\u5104\u500b\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u4ed6\u306e\u7814\u7a76\u3067\u306f\u3001\u814b\u7aa9\u30ea\u30f3\u30d1\u7bc0\u751f\u691c\u3067\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e2\u56de\u76ee\u306e\u6295\u4e0e\u304b\u308960\u65e5\u5f8c\u307e\u3067\u3001\u30ef\u30af\u30c1\u30f3\u306e\uff4dRNA\u3068\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304c\u4f9d\u7136\u3068\u3057\u3066\u5b58\u5728\u3057\u3066\u3044\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u3053\u306e\u7814\u7a76\u3067\u306f\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u6700\u521d\u306e\u6570\u65e5\u3067\u8840\u6f3f\u4e2d\u306b\u767a\u898b\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306f\u5e73\u574747pg\/mL\u3067\u3057\u305f\u306e\u3067\u30015000\u5104\u500b\u524d\u5f8c\u3001\u8840\u4e2d\u306b\u5b58\u5728\u3057\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u3092\u542b\u3080\u5faa\u74b0\u30a8\u30ad\u30bd\u30bd\u30fc\u30e0\u306f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c14\u65e5\u76ee\u306b\u3082\u767a\u898b\u3055\u308c\u3001\u30d6\u30fc\u30b9\u30bf\u30fc\u6295\u4e0e\u5f8c\u306b\u5897\u52a0\u3057\u3001\u6700\u59274\u304b\u6708\u9593\u6301\u7d9a\u3057\u305f\u3057\u305f\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u3002\u3053\u306e\u5c0f\u80de\u306f\u3001\u514d\u75ab\u5fdc\u7b54\u3092\u523a\u6fc0\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u307e\u3060\u306f\u3063\u304d\u308a\u3057\u305f\u3053\u3068\u306f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306e\u53d7\u5bb9\u4f53\u306f\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3084\u5668\u5b98\u3067\u767a\u73fe\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u3053\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u5358\u7d14\u306a\u300c\u6297\u539f\u300d\u3068\u3044\u3046\u306e\u3092\u660e\u3089\u304b\u306b\u8d85\u3048\u305f\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306f\u5341\u5206\u306b\u9ad8\u3044\u3067\u3057\u3087\u3046\u3002\u8840\u4e2d\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304c\u8840\u5c0f\u677f\u3092\u6d3b\u6027\u5316\u3057\u3066\u8840\u6813\u3092\u4f5c\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3055\u3089\u306b\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304c\u8840\u6db2\u8133\u95a2\u9580\u3082\u901a\u904e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u795e\u7d4c\u5b66\u7684\u75c7\u72b6\u3092\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u5b9f\u969b\u306b\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306f\u30013\u56de\u76ee\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u53d7\u3051\u3066\u304b\u30893\u9031\u9593\u5f8c\u306b\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306e\u8133\u3068\u5fc3\u81d3\u306e\u8840\u7ba1\u58c1\u3067\u691c\u51fa\u3055\u308c\u305f\u306e\u3067\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n

\u3055\u3089\u306b\u5b9f\u9a13\u7684\u306b\u306f\u30d5\u30a1\u30a4\u30b6\u30fc\u306e\u30ef\u30af\u30c1\u30f3\u3067mRNA\u304c\u30d2\u30c8\u306e\u809d\u7d30\u80de\u306b\u6025\u901f\u306b\u4fb5\u5165\u3057\u305f\u5f8c\u3001\u6570\u6642\u9593\u4ee5\u5185\u306bDNA\u3078\u306e\u300c\u9006\u8ee2\u5199\u300d\u304c\u8d77\u304d\u307e\u3057\u305f\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u30ef\u30af\u30c1\u30f3\u306emRNA \u304b\u3089\u9006\u8ee2\u5199\u3055\u308c\u305fDNA\u304c\u7d30\u80de\u30b2\u30ce\u30e0\u306b\u7d44\u307f\u8fbc\u307e\u308c\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u306f\u307e\u3060\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u907a\u4f1d\u6bd2\u6027\u306e\u526f\u4f5c\u7528\u306e\u53ef\u80fd\u6027\u3055\u3048\u3042\u308a\u307e\u3059\u3002DNA\u306b\u9006\u8ee2\u5199\u3055\u308c\u308b\u5834\u5408\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u306e\u5408\u6210\u306f\u9577\u671f\u9593\u6301\u7d9a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3067\u3082\u3001\u3082\u3057\u304b\u3057\u305f\u3089\u3001mRNA\u3060\u3051\u3067\u306a\u304fDNA\u304c\u30ef\u30af\u30c1\u30f3\u306b\u6df7\u5165\u3057\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u3044\u3046\u8a18\u4e8b\u307e\u3067\u5b58\u5728\u3057\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u305d\u3046\u3060\u3068\u3057\u305f\u3089\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u53d7\u3051\u305f\u4eba\u306e\u8840\u6db2\u4e2d\u306b\u3001\u63a5\u7a2e\u5f8c\u6570\u9031\u9593\u307e\u305f\u306f\u6570\u304b\u6708\u306b\u308f\u305f\u3063\u3066\u6301\u7d9a\u7684\u306b\u8a8d\u3081\u3089\u308c\u308b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u3092\u8aac\u660e\u3067\u304d\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306f\u6700\u521d\u304b\u3089\u30a6\u30bd\u3070\u304b\u308a\u3067\u3059\u3002\u305d\u3093\u306a\u3082\u306e\u3092\u8a8d\u3081\u305f\u56fd\u3082\u56fd\u3067\u3059\u3002\u5373\u6642\u4e2d\u6b62\u3092\u3002\u305d\u3057\u3066\u8a73\u7d30\u306a\u8abf\u67fb\u3092\u3002<\/p>\n

\u300cCirculating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis\u300d<\/span><\/p>\n

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