{"id":22212,"date":"2023-03-27T12:47:27","date_gmt":"2023-03-27T03:47:27","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=22212"},"modified":"2023-03-27T12:47:27","modified_gmt":"2023-03-27T03:47:27","slug":"%e9%85%b8%e5%8c%96hdl%e3%81%8a%e3%82%88%e3%81%b3%e9%85%b8%e5%8c%96ldl%e3%81%a8%e7%b3%96%e8%b3%aa%e9%81%8e%e5%89%b0%e7%97%87%e5%80%99%e7%be%a4","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=22212","title":{"rendered":"\u9178\u5316HDL\u304a\u3088\u3073\u9178\u5316LDL\u3068\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4"},"content":{"rendered":"<p>\u7cd6\u5c3f\u75c5\u3084\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u306f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u308c\u306b\u3088\u308a\u8840\u4e2d\u306e\u8102\u8cea\u3067\u3042\u308bHDL\u3001LDL\u3082\u9178\u5316\u3057\u307e\u3059\u3002<\/p>\n<p>10\u4ee3\u306e\u82e5\u8005\u3067\u3082\u80a5\u6e80\u3084\u7cd6\u5c3f\u75c5\u306b\u4f34\u3046\u9178\u5316HDL\u3084\u9178\u5316LDL\u306f\u5897\u52a0\u3057\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f11\uff5e18\u6b73\u306e\u7537\u5973\uff08\u6a19\u6e96\u4f53\u91cd37\u4eba\u3001\u80a5\u6e8038\u4eba\u30012\u578b\u7cd6\u5c3f\u75c542\u4eba\uff09\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<div class=\"caption\">\n<p id=\"P36\">\u53c2\u52a0\u8005\u306e\u7279\u5fb4\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<\/div>\n<div class=\"xtable\">\n<table class=\"rendered small default_table\" style=\"width: 76.104%; height: 255px;\" frame=\"hsides\" rules=\"groups\">\n<thead>\n<tr>\n<th align=\"left\" valign=\"top\"><\/th>\n<th align=\"center\" valign=\"top\">\u6a19\u6e96\u4f53\u91cd<br \/>\n(N = 37)<\/th>\n<th align=\"center\" valign=\"top\">\u80a5\u6e80<br \/>\n(N = 38)<\/th>\n<th align=\"center\" valign=\"top\">2\u578b\u7cd6\u5c3f\u75c5<br \/>\n(N = 42)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td align=\"left\" valign=\"top\">\u5973\u6027\/\u7537\u6027\u306e\u6570<\/td>\n<td align=\"center\" valign=\"top\">17\/20<\/td>\n<td align=\"center\" valign=\"top\">17\/21<\/td>\n<td align=\"center\" valign=\"top\">27\/15<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">\u5e74\u9f62<\/td>\n<td align=\"center\" valign=\"top\">14.6 \u00b1 1.7<\/td>\n<td align=\"center\" valign=\"top\">14.8 \u00b1 1.6<\/td>\n<td align=\"center\" valign=\"top\">15.6 \u00b1 2.0<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">BMI<\/td>\n<td align=\"center\" valign=\"top\">19.7 \u00b1 1.4<\/td>\n<td align=\"center\" valign=\"top\">33.2 \u00b1 5.6<\/td>\n<td align=\"center\" valign=\"top\">39.4 \u00b1 9.4<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">\u7dcf\u4f53\u8102\u80aa\u3001%<\/td>\n<td align=\"center\" valign=\"top\">25.6 \u00b1 8.2<\/td>\n<td align=\"center\" valign=\"top\">44.9 \u00b1 6.7<\/td>\n<td align=\"center\" valign=\"top\">47.6 \u00b1 7.0<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">\u4f53\u5e79\u8102\u80aa\u3001kg<\/td>\n<td align=\"center\" valign=\"top\">5.3 \u00b1 2.1<\/td>\n<td align=\"center\" valign=\"top\">22.2 \u00b1 8.3<\/td>\n<td align=\"center\" valign=\"top\">28.4 \u00b1 11.3<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">\u53ce\u7e2e\u671f\u8840\u5727\u3001mmHg<\/td>\n<td align=\"center\" valign=\"top\">109 \u00b1 6<\/td>\n<td align=\"center\" valign=\"top\">118 \u00b1 8<\/td>\n<td align=\"center\" valign=\"top\">118 \u00b1 13<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" valign=\"top\">\u62e1\u5f35\u671f\u8840\u5727\u3001mmHg<\/td>\n<td align=\"center\" valign=\"top\">58 \u00b1 4<\/td>\n<td align=\"center\" valign=\"top\">60 \u00b1 7<\/td>\n<td align=\"center\" valign=\"top\">62 \u00b1 8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div class=\"xtable\">\n<table class=\"rendered small default_table\" style=\"width: 76.5478%; height: 429px;\" frame=\"hsides\" rules=\"groups\">\n<thead>\n<tr>\n<th style=\"width: 50.9934%;\" align=\"left\" valign=\"top\"><\/th>\n<th style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">\u6a19\u6e96\u4f53\u91cd<\/th>\n<th style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">\u80a5\u6e80<\/th>\n<th style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">2\u578b\u7cd6\u5c3f\u75c5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"top\">\u8840\u7cd6\u5024\u3001mg\/dl (mmol\/L)<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">84 \u00b1 6<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">85 \u00b1 6<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">130 \u00b1 50<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"top\">\u30a4\u30f3\u30b9\u30ea\u30f3\u3001\u03bclU\/ml<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">7.2 \u00b1 5.2<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">22.5 \u00b1 12.8<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">37.4 \u00b1 24.6<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"top\">HOMA-IR\u3001AU<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">1.5 \u00b1 1.1<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">4.7 \u00b1 2.7<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">11.6 \u00b1 8.6<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"middle\">\u4e2d\u6027\u8102\u80aa\u3001mg\/dl<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">71 \u00b1 34<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">115 \u00b1 56<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">122 \u00b1 52<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"top\">\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001mg\/dl<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">155 \u00b1 29<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">184 \u00b1 77<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">157 \u00b1 30<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"top\">CRP\u3001mg\/l<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">0.5 \u00b1 0.7<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">4.4 \u00b1 5.8<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">6.0 \u00b1 6.3<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9934%;\" align=\"left\" valign=\"middle\">\u30df\u30a8\u30ed\u30da\u30eb\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\uff08\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u6307\u6a19\uff09\u3001ng\/ml<\/td>\n<td style=\"width: 16.0596%;\" align=\"center\" valign=\"top\">59 \u00b1 53<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">80 \u00b1 70<\/td>\n<td style=\"width: 16.3907%;\" align=\"center\" valign=\"top\">111 \u00b1 105<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5f53\u7136\u3001\u6b63\u5e38\u306e\u4f53\u91cd\u306b\u6bd4\u3079\u3066\u3001\u80a5\u6e80\u3084\u7cd6\u5c3f\u75c5\u3067\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u3084HOMA-IR\u304c\u9ad8\u304f\u3001\u4e2d\u6027\u8102\u80aa\u5024\u3082\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u708e\u75c7\u306eCRP\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u30df\u30a8\u30ed\u30da\u30eb\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\u3082\u540c\u69d8\u3067\u3059\u3002<\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9549762\/bin\/nihms-1839824-f0001.jpg?w=640&#038;ssl=1\" alt=\"\u5199\u771f\u3084\u30a4\u30e9\u30b9\u30c8\u306a\u3069\u3092\u4fdd\u6301\u3059\u308b\u5916\u90e8\u30d5\u30a1\u30a4\u30eb\u3002\u30aa\u30d6\u30b8\u30a7\u30af\u30c8\u540d\u306f nihms-1839824-f0001.jpg\" \/><\/p>\n<\/div>\n<\/div>\n<p>\u4e0a\u306e\u56f3\u306fNW\uff08\u6a19\u6e96\u4f53\u91cd\uff09\u3001Ob\uff08\u80a5\u6e80\uff09\u3001T2DM\uff082\u578b\u7cd6\u5c3f\u75c5\uff09\u306eHDL\u304a\u3088\u3073LDL\u306b\u3064\u3044\u3066\u3067\u3059\u3002\u6a19\u6e96\u4f53\u91cd\u3067\u3059\u3089\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306a\u306e\u3067HDL\u306f\u4f4e\u3081\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u308c\u306b\u3082\u307e\u3057\u3066\u80a5\u6e80\u3084\u7cd6\u5c3f\u75c5\u3067\u306fHDL\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002LDL\u306f\u80a5\u6e80\u306e\u7537\u6027\u306e\u307f\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u9178\u5316HDL\u306f\u7cd6\u5c3f\u75c5\u3067\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u7537\u6027\u3067\u3088\u308a\u9855\u8457\u3067\u3057\u305f\u3002\u9178\u5316LDL\u306f\u80a5\u6e80\u3067\u3082\u7cd6\u5c3f\u75c5\u3067\u3082\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002HDL\u304a\u3088\u3073LDL\u306b\u5bfe\u3057\u3066\u306e\u9178\u5316HDL\u3001\u9178\u5316LDL\u306f\u7cd6\u5c3f\u75c5\u3067\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9549762\/bin\/nihms-1839824-f0002.jpg?w=640&#038;ssl=1\" alt=\"\u5199\u771f\u3084\u30a4\u30e9\u30b9\u30c8\u306a\u3069\u3092\u4fdd\u6301\u3059\u308b\u5916\u90e8\u30d5\u30a1\u30a4\u30eb\u3002\u30aa\u30d6\u30b8\u30a7\u30af\u30c8\u540d\u306f nihms-1839824-f0002.jpg\" \/><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u9178\u5316LDL\u3068\u9178\u5316HDL\u306e\u95a2\u4fc2\u3001\u9664\u8102\u80aa\u4f53\u91cd\u3068\u9178\u5316HDL\u306e\u95a2\u9023\u3067\u3059\u3002\u9178\u5316HDL\u306f\u9178\u5316LDL\u3084\u9664\u8102\u80aa\u4f53\u91cd\u3068\u95a2\u9023\u304c\u3042\u308a\u3001\u305d\u306e\u4ed6\u306b\u3082\u4f53\u5e79\u9664\u8102\u80aa\u4f53\u91cd\u3001\u4f53\u91cd \u3001\u8102\u80aa\u91cf\u3001BMI\u3068\u3082\u95a2\u9023\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u305f\u3060\u3001\u4e0a\u306e\u30b0\u30e9\u30d5\u3092\u898b\u3066\u308f\u304b\u308b\u3088\u3046\u306b\u3001\u7cd6\u5c3f\u75c5\u3067\u306f\u9065\u304b\u9ad8\u3044\u9178\u5316HDL\u3092\u793a\u3059\u4eba\u304c\u591a\u304f\u3044\u307e\u3057\u305f\u3002\u7b4b\u8089\u304c\u591a\u3044\u65b9\u304c\u9178\u5316HDL\u304c\u591a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u306e\u3082\u3061\u3087\u3063\u3068\u4e0d\u601d\u8b70\u3067\u3059\u304c\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9549762\/bin\/nihms-1839824-f0003.jpg?w=640&#038;ssl=1\" alt=\"\u5199\u771f\u3084\u30a4\u30e9\u30b9\u30c8\u306a\u3069\u3092\u4fdd\u6301\u3059\u308b\u5916\u90e8\u30d5\u30a1\u30a4\u30eb\u3002\u30aa\u30d6\u30b8\u30a7\u30af\u30c8\u540d\u306f nihms-1839824-f0003.jpg\" \/><\/p>\n<p>\u9178\u5316LDL\u306fApoB\u3001\u4e2d\u6027\u8102\u80aa\u3001HOMA-IR\u3001\u4f53\u5e79\u8102\u80aa\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u8840\u7cd6\u5024\u3001\u4f53\u91cd\u3001\u8102\u80aa\u91cf\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3001BMI\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>10\u4ee3\u306e\u82e5\u8005\u3067\u3055\u3048\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u3088\u308b\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u6652\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f7c\u3089\u306f\u3059\u3050\u306b\u75c5\u6c17\u3092\u767a\u75c7\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u3053\u306e\u72b6\u614b\u304c\u7a4d\u3082\u308a\u7a4d\u3082\u3063\u3066\u6bd4\u8f03\u7684\u65e9\u3044\u5e74\u9f62\u3067\u4f55\u3089\u304b\u306e\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u75c7\u72b6\u304c\u51fa\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u3053\u3068\u306f\u826f\u304f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u3053\u3068\u3092\u554f\u984c\u8996\u3059\u308b\u4eba\u304c\u591a\u3044\u3067\u3057\u3087\u3046\u304c\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u826f\u3044\u3082\u60aa\u3044\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3067\u91cd\u8981\u306a\u3082\u306e\u3067\u3059\u3002\u305d\u308c\u3092\u904b\u3076HDL\u3084LDL\u306e\u8cea\u304c\u554f\u984c\u3067\u3059\u3002\u9178\u5316\u3082\u3082\u3061\u308d\u3093\u3067\u3059\u304c\u3001\u7cd6\u5316\u3082\u975e\u5e38\u306b\u6709\u5bb3\u3067\u3059\u3002\u7cd6\u5316HDL\u3001\u7cd6\u5316LDL\u304c\u6a5f\u80fd\u969c\u5bb3\u3092\u8d77\u3053\u3057\u3066\u69d8\u3005\u306a\u6709\u5bb3\u306a\u3053\u3068\u304c\u8d77\u304d\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u306f\u9178\u5316\u3082\u7cd6\u5316\u3082\u975e\u5e38\u306b\u4fc3\u9032\u3055\u308c\u307e\u3059\u3002\u307e\u305a\u306f\u82e5\u3044\u3046\u3061\u304b\u3089\u306e\u7cd6\u8cea\u5236\u9650\u304c\u57fa\u672c\u3067\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cOxidized HDL and LDL in adolescents with type 2 diabetes compared to normal weight and obese peers\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c2\u578b\u7cd6\u5c3f\u75c5\u306e\u9752\u5e74\u306b\u304a\u3051\u308b\u9178\u5316HDL\u304a\u3088\u3073\u9178\u5316LDL\u306e\u6b63\u5e38\u4f53\u91cd\u304a\u3088\u3073\u80a5\u6e80\u3068\u306e\u6bd4\u8f03\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25881918\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7cd6\u5c3f\u75c5\u3084\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u306f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u308c\u306b\u3088\u308a\u8840\u4e2d\u306e\u8102\u8cea\u3067\u3042\u308bHDL\u3001LDL\u3082\u9178\u5316\u3057\u307e\u3059\u3002 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