{"id":2292,"date":"2017-08-12T00:01:32","date_gmt":"2017-08-11T15:01:32","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=2292"},"modified":"2017-08-12T00:01:32","modified_gmt":"2017-08-11T15:01:32","slug":"post-2292","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=2292","title":{"rendered":"\u9244\u306f\u304c\u3093\u306e\u539f\u56e0\u306e\u3072\u3068\u3064\u3068\u306a\u308b\uff08\u9577\u6587\uff09"},"content":{"rendered":"<p>\u3053\u308c\u307e\u3067\u3082\u3001\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=2017\" target=\"_blank\" rel=\"noopener\">\u9244\u3068\u304c\u3093\u306e\u95a2\u4fc2\u3000\u6570\u5e74\u5f8c\u306b\u5f8c\u6094\u3057\u306a\u3044\u305f\u3081\u306b<\/a>\u300d\u3084<a href=\"http:\/\/promea2014.com\/blog\/?p=1131\" target=\"_blank\" 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data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u9244\u3068\u304c\u30931\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?fit=300%2C274&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?fit=640%2C585&amp;ssl=1\" class=\"alignnone size-medium wp-image-2320\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?resize=300%2C274\" alt=\"\" width=\"300\" height=\"274\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?resize=300%2C274&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?resize=320%2C293&amp;ssl=1 320w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/c0401293d9503f761442b076921cde6c.png?w=656&amp;ssl=1 656w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><span style=\"color: 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[Fe\u00a0<sup>3+<\/sup>\u00a0]\u00a0<sub>2<\/sub>\uff09\u306f\u8840\u6d41\u3092\u5faa\u74b0\u3057\u3001\u9244\u3092\u5229\u7528\u90e8\u4f4d\u306b\u9001\u308a\u3053\u307f\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u90e8\u4f4d\u306e\u4e2d\u306e\u4e3b\u8981\u306a\u3082\u306e\u306f\u3001\u9244\u304c\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u304a\u3088\u3073\u8d64\u8840\u7403\u306e\u5408\u6210\u306b\u4f7f\u7528\u3055\u308c\u308b\u9aa8\u9ac4\u3067\u3059\u3002\u8d64\u8840\u7403\u306f\u7d30\u7db2\u5185\u76ae\u7cfb\u306e\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u3088\u3063\u3066\u7570\u5316\u3055\u308c\u308b\u307e\u3067\u306b\u7d0490\u65e5\u9593\u4f53\u5185\u3092\u5faa\u74b0\u3057\u307e\u3059\u3002\u9244\u306f\u7570\u5316\u3055\u308c\u305f\u30d8\u30e0\u304b\u3089\u653e\u51fa\u3055\u308c\u3001\u30d5\u30a7\u30ed\u30dd\u30fc\u30c1\u30f3\u306e\u4f5c\u7528\u306b\u3088\u308a\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u304b\u3089\u6d41\u51fa\u3057\u3001\u8840\u6d41\u306e\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u306b\u307e\u305f\u4e57\u305b\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u3053\u3068\u306f\u300c\u9244\u306e\u30ea\u30b5\u30a4\u30af\u30eb\u300d\u3068\u547c\u307e\u3059\u3002\u307e\u305f\u30013\u4fa1\u9244\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u8907\u5408\u4f53\u306f\u672b\u68a2\u7d44\u7e54\u304a\u3088\u3073\u904e\u5270\u306e\u9244\u306e\u8caf\u8535\u306e\u305f\u3081\u306e\u4e3b\u8981\u5668\u5b98\u3067\u3042\u308b\u809d\u81d3\u306b\u9001\u3089\u308c\u307e\u3059\u3002\u5c11\u91cf\u306e\u9244\u306f\u7d44\u7e54\u306a\u3069\u306e\u5265\u96e2\u306b\u3088\u3063\u3066\u5931\u308f\u308c\u307e\u3059\u304c\u3001\u9244\u306e\u6392\u6cc4\u7d4c\u8def\u306f\u306a\u3044\u305f\u3081\u3001\u4f53\u5185\u306e\u9244\u5206\u306e\u30ec\u30d9\u30eb\u306f\u4e3b\u306b\u5438\u53ce\u6bb5\u968e\u3067\u8abf\u7bc0\u3055\u308c\u307e\u3059\u3002\u904e\u5270\u306a\u9244\u306f\u3001\u5168\u8eab\u306e\u9244\u30db\u30e1\u30aa\u30b9\u30bf\u30b7\u30b9\u3092\u6700\u3082\u8abf\u7bc0\u3057\u3066\u3044\u308b\u30da\u30d7\u30c1\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u30d8\u30d7\u30b7\u30b8\u30f3\u306e\u5408\u6210\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002\u30d8\u30d7\u30b7\u30b8\u30f3\u306f\u30d5\u30a7\u30ed\u30dd\u30fc\u30c1\u30f3\u3068\u7d50\u5408\u3057\u3066\u5206\u89e3\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u304c\u3001\u8178\u7d30\u80de\u304b\u3089\u306e\u98df\u7269\u9244\u306e\u5438\u53ce\u304a\u3088\u3073\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u3088\u308b\u9244\u306e\u518d\u5faa\u74b0\u306e\u4e21\u65b9\u3092\u963b\u5bb3\u3057\u307e\u3059\u3002\u30d8\u30d7\u30b7\u30b8\u30f3\u306f\u307e\u305f\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306b\u5fdc\u3058\u3066\u8a98\u5c0e\u3055\u308c\u308b\u306e\u3067\u3001\u304c\u3093\u306e\u8ca7\u8840\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span 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data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?fit=300%2C235&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?fit=640%2C500&amp;ssl=1\" class=\"alignnone size-medium wp-image-2322\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?resize=300%2C235\" alt=\"\" width=\"300\" height=\"235\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?resize=300%2C235&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?resize=320%2C250&amp;ssl=1 320w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2017\/08\/557f4da3015189be2542eff98af5ce38.png?w=656&amp;ssl=1 656w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\">\u9244\u306f2\u3064\u306e3\u4fa1\u9244\u30a4\u30aa\u30f3\u3092\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u306b\u7d50\u5408\u3057\u305f\u72b6\u614b\u3067\u4f53\u5185\u3092\u5faa\u74b0\u3057\u307e\u3059\u3002\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u306b\u7d50\u5408\u3057\u305f\u9244\u306f\u3001\u307b\u3068\u3093\u3069\u306e\u7d30\u80de\u306e\u7d30\u80de\u819c\u4e0a\u306e\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u53d7\u5bb9\u4f531\uff08TFR1\uff09\u306b\u7d50\u5408\u3057\u3001\u53d6\u308a\u8fbc\u307e\u308c\u307e\u3059\u3002\u30a8\u30f3\u30c9\u30bd\u30fc\u30e0\u306e\u9178\u6027\u74b0\u5883\u306b\u304a\u3044\u3066\u30013\u4fa1\u9244\u306f\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30ea\u30f3\u304b\u3089\u653e\u51fa\u3055\u308c\u3001STEAP3\u306b\u3088\u308a2\u4fa1\u9244\u306b\u306a\u308a\u307e\u3059\u3002DMT1\u3068\u3044\u30462\u4fa1\u91d1\u5c5e\u8f38\u9001\u4f53\u306b\u3088\u308a\uff12\u4fa1\u9244\u30a4\u30aa\u30f3\u306f\u3001\u4e0d\u5b89\u5b9a\u9244\u30d7\u30fc\u30eb\u3068\u547c\u3070\u308c\u308b\u9244\u306e\u30d7\u30fc\u30eb\u3078\u30a8\u30f3\u30c9\u30bd\u30fc\u30e0\u304b\u3089\u6392\u51fa\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u30d7\u30fc\u30eb\u304b\u3089\u3001\u9244\u306f\u8907\u6570\u306e\u7d30\u80de\u5185\u306e\u69d8\u3005\u306a\u3053\u3068\u306b\u5229\u7528\u3055\u308c\u308b\u3002DNA\u306e\u5408\u6210\u3084\u4fee\u5fa9\u3001\u30d8\u30e0\u304a\u3088\u3073\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u9244 &#8211; \u786b\u9ec4\u30af\u30e9\u30b9\u30bf\u30fc\u306e\u5408\u6210\u306b\u3082\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u6b21\u306b\u30af\u30a8\u30f3\u9178\u30b5\u30a4\u30af\u30eb\u3001\u9178\u5316\u7684\u30ea\u30f3\u9178\u5316\u3001\u304a\u3088\u3073\u4ed6\u306e\u591a\u304f\u306e\u5fc5\u9808\u6a5f\u80fd\u3092\u884c\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5408\u6210\u306b<span style=\"color: #ff0000;\">\u5fc5\u8981\u306a\u30ec\u30d9\u30eb\u3092\u8d85\u3048\u308b\u300c\u904e\u5270\u306e\u9244\u300d<\/span>\u306f\u3001\u9244\u8caf\u8535\u30bf\u30f3\u30d1\u30af\u8cea\u30d5\u30a7\u30ea\u30c1\u30f3\u306b\u8caf\u8535\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"color: 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style=\"color: #0000ff;\">E1a\u764c\u907a\u4f1d\u5b50\u306f\u540c\u69d8\u306b\u30d5\u30a7\u30ea\u30c1\u30f3\u3092\u6291\u5236\u3057\u307e\u3059\u3002HRAS<em>\u306e<\/em>\u764c\u907a\u4f1d\u5b50\u3082\u30d5\u30a7\u30ea\u30c1\u30f3\u3092\u6291\u5236\u3057\u3001\u4e0d\u5b89\u5b9a\u306a\u9244\u306e\u30d7\u30fc\u30eb\u3092\u5897\u52a0\u3055\u305b\u3001\u5897\u6b96\u523a\u6fc0\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u9244\u8caf\u8535\u30bf\u30f3\u30d1\u30af\u8cea\u30d5\u30a7\u30ea\u30c1\u30f3\u306b\u304a\u3051\u308b\u764c\u907a\u4f1d\u5b50\u8a98\u5c0e\u6027\u306e\u5909\u5316\u304c\u3001\u4e0d\u5b89\u5b9a\u306a\u9244\u306e\u30d7\u30fc\u30eb\u3092\u5897\u52a0\u3055\u305b\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3092\u5897\u52a0\u3055\u305b\u308b\u306e\u306b\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u306f\u5b9f\u8a3c\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"color: 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style=\"color: #0000ff;\">\u9244\u306f\u816b\u760d\u306e\u958b\u59cb\u304a\u3088\u3073\u816b\u760d\u306e\u4fc3\u9032\u306e\u4e21\u65b9\u306b\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: 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style=\"color: #0000ff;\">\u307e\u3060\u5b8c\u5168\u306b\u306f\u7406\u89e3\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u9244\u5236\u5fa1\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u904e\u591a\u304c\u6700\u8fd1\u306b\u306a\u3063\u3066\u304c\u3093\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"color: 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\/>\n<span style=\"color: #0000ff;\"> 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style=\"color: #ff0000;\">\u300c\u9244\u306f\u304c\u3093\u306e\u539f\u56e0\u306e\u4e00\u3064\u3067\u3042\u308b\u300d<\/span>\u3068\u3044\u3046\u306e\u304c<span style=\"color: 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href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23594855\" target=\"_blank\" 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