{"id":23127,"date":"2023-06-27T21:34:14","date_gmt":"2023-06-27T12:34:14","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=23127"},"modified":"2023-06-27T21:34:14","modified_gmt":"2023-06-27T12:34:14","slug":"%e3%82%a4%e3%83%b3%e3%82%b9%e3%83%aa%e3%83%b3%e6%8a%b5%e6%8a%97%e6%80%a7%e3%81%af%e8%aa%8d%e7%9f%a5%e6%a9%9f%e8%83%bd%e4%bd%8e%e4%b8%8b%e3%82%92%e6%8b%9b%e3%81%8f","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=23127","title":{"rendered":"\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3092\u62db\u304f"},"content":{"rendered":"

\u8a8d\u77e5\u75c7\u306e\u591a\u304f\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\uff13\u578b\u7cd6\u5c3f\u75c5\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u664245\uff5e64\u6b73\u3067\u8a8d\u77e5\u75c7\u306e\u306a\u30447,148\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3068\u305d\u306e6\u5e74\u5f8c\u306e\u8a8d\u77e5\u6a5f\u80fd\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u3069\u306e\u30ec\u30d9\u30eb\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u307e\u305f\u306f\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u304b\u306f\u4e0d\u660e\u3067\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u4eca\u56de\u306f\u521d\u8a3a\u6642\u306b\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u6e2c\u5b9a\u3057\u305f\u3059\u3079\u3066\u306e\u4eba\u306b\u57fa\u3065\u3044\u3066\u300175\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u4ee5\u4e0a\u3092\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3068\u5b9a\u7fa9\u3057\u307e\u3057\u305f\u300275\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306f\u3001\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3\u306b\u3064\u3044\u3066\u306f14.0mU\/l\u3001HOMA \u306b\u3064\u3044\u3066\u306f3.9\u3067\u3057\u305f\u3002\u307e\u305f\u3001\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3>12.2mU\/l\u304a\u3088\u3073HOMA>2.6\u3067\u3082\u5206\u3051\u307e\u3057\u305f\u3002<\/p>\n

\u8a8d\u77e5\u30c6\u30b9\u30c8\u306b\u306f\u3001DWR\u30c6\u30b9\u30c8\u3001DSS\u30c6\u30b9\u30c8\u3001WF\u30c6\u30b9\u30c8\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002DWR\u306f\u3001\u8a00\u8a9e\u5b66\u7fd2\u3068\u6700\u8fd1\u306e\u8a18\u61b6\u306e\u30c6\u30b9\u30c8\u3067\u3059\u3002DSS\u30b9\u30b3\u30a2\u306f\u300190\u79d2\u306e\u5236\u9650\u6642\u9593\u5185\u306b\u6b63\u3057\u304f\u63cf\u753b\u3055\u308c\u305f\u30b7\u30f3\u30dc\u30eb\u306e\u6570\u3067\u3059\u3002DSS\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3055\u308c\u308b\u8a8d\u77e5\u6a5f\u80fd\u3068\u7cbe\u795e\u904b\u52d5\u80fd\u529b\u306e\u69cb\u6210\u8981\u7d20\u306b\u306f\u3001\u53cd\u5fdc\u901f\u5ea6\u3001\u6301\u7d9a\u7684\u306a\u6ce8\u610f\u3001\u8996\u899a\u7a7a\u9593\u30b9\u30ad\u30eb\u3001\u9023\u5408\u5b66\u7fd2\u3001\u304a\u3088\u3073\u8a18\u61b6\u304c\u542b\u307e\u308c\u307e\u3059\u3002WF\u30c6\u30b9\u30c8\u306f\u3001\u7279\u5b9a\u306e\u6587\u5b57\u3067\u59cb\u307e\u308b\u5358\u8a9e\u3092\u691c\u7d22\u3059\u308b\u969b\u306e\u7cbe\u795e\u7684\u306a\u654f\u6377\u6027\u3092\u6e2c\u5b9a\u3057\u307e\u3059\u3002WF\u30c6\u30b9\u30c8\u306f\u3001\u8133\u306e\u524d\u982d\u8449\u306e\u640d\u50b7\u306b\u7279\u306b\u654f\u611f\u3067\u3059\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3042\u308a<\/span><\/th>\n\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u306a\u3057<\/span><\/th>\n<\/tr>\n<\/thead>\n
\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3 (\u30ab\u30c3\u30c8\u30aa\u30d5 75 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb)\u00a0<\/span><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DWR\u00a0<\/span><\/td>\n6.58\u00b11.42\u00a0<\/span><\/td>\n6.83\u00b11.42\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DWR\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22120.254\u00b11.53\u00a0<\/span><\/td>\n\u22120.129\u00b11.54\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DSS\u00a0<\/span><\/td>\n43.0\u00b113.7\u00a0<\/span><\/td>\n47.9\u00b113.1\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DSS\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22122.74\u00b17.30\u00a0<\/span><\/td>\n\u22122.51\u00b16.85\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 WF\u00a0<\/span><\/td>\n32.5\u00b112.3\u00a0<\/span><\/td>\n35.1\u00b112.1\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003WF\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22121.19\u00b17.86\u00a0<\/span><\/td>\n\u22120.532 \u00b1 7.92\u00a0<\/span><\/td>\n<\/tr>\n
\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3 (\u30ab\u30c3\u30c8\u30aa\u30d5 12.2 mU\/l)\u00a0<\/span><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DWR\u00a0<\/span><\/td>\n6.59\u00b11.40\u00a0<\/span><\/td>\n6.85\u00b11.43\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DWR\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22120.205\u00b11.57\u00a0<\/span><\/td>\n\u22120.134 \u00b1 1.55\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DSS\u00a0<\/span><\/td>\n43.7\u00b113.7\u00a0<\/span><\/td>\n48.1\u00b113.1\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DSS\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22122.66\u00b17.14\u00a0<\/span><\/td>\n\u22122.51\u00b16.86\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 WF\u00a0<\/span><\/td>\n32.7\u00b112.2\u00a0<\/span><\/td>\n35.3\u00b112.1\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003WF\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22121.035\u00b17.83\u00a0<\/span><\/td>\n\u22120.520 \u00b1 7.94\u00a0<\/span><\/td>\n<\/tr>\n
HOMA (\u30ab\u30c3\u30c8\u30aa\u30d5 75 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb)\u00a0<\/span><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DWR\u00a0<\/span><\/td>\n6.56\u00b11.41\u00a0<\/span><\/td>\n6.82\u00b11.43\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DWR\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22120.277 \u00b1 1.52\u00a0<\/span><\/td>\n\u22120.128\u00b11.54\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DSS\u00a0<\/span><\/td>\n42.8\u00b113.8\u00a0<\/span><\/td>\n47.8\u00b113.2\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DSS\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22122.74\u00b17.26\u00a0<\/span><\/td>\n\u22122.51\u00b16.87\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 WF\u00a0<\/span><\/td>\n32.3\u00b112.4\u00a0<\/span><\/td>\n35.0\u00b112.1\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003WF\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22121.08\u00b17.84\u00a0<\/span><\/td>\n\u22120.570 \u00b1 7.93\u00a0<\/span><\/td>\n<\/tr>\n
HOMA (\u30ab\u30c3\u30c8\u30aa\u30d5 2.6)\u00a0<\/span><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DWR\u00a0<\/span><\/td>\n6.64\u00b11.41\u00a0<\/span><\/td>\n6.86\u00b11.43\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DWR\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22120.211\u00b11.54\u00a0<\/span><\/td>\n\u22120.120\u00b11.54\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 DSS\u00a0<\/span><\/td>\n44.4\u00b113.7\u00a0<\/span><\/td>\n48.4\u00b113.0\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003DSS\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22122.57\u00b17.00\u00a0<\/span><\/td>\n\u22122.54\u00b16.91\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3 WF\u00a0<\/span><\/td>\n33.1\u00b112.1\u00a0<\/span><\/td>\n35.5\u00b112.2\u00a0<\/span><\/td>\n<\/tr>\n
\u2003\u2003\u2003\u2003WF\u5909\u5316\u30b9\u30b3\u30a2\u00a0<\/span><\/td>\n\u22120.88\u00b17.84\u00a0<\/span><\/td>\n\u22120.53\u00b17.96\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u306f\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3\u304a\u3088\u3073\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u8868\u3059HOMA\u306b\u304a\u3044\u3066\u300175\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3067\u308212.2mU\/l\u304a\u3088\u30732.6\u306e\u30ab\u30c3\u30c8\u30aa\u30d5\u5024\u3067\u3082\u3001\u307b\u3068\u3093\u3069\u3069\u308c\u3082\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u3044\u65b9\u304c\u30b9\u30b3\u30a2\u304c\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u3055\u3089\u306b6\u5e74\u5f8c\u306e\u5909\u5316\u30b9\u30b3\u30a2\u3067\u3082\u591a\u304f\u306e\u8a8d\u77e5\u6a5f\u80fd\u8a55\u4fa1\u30c6\u30b9\u30c8\u3067\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u3042\u308b\u65b9\u304c\u5927\u5e45\u306b\u30b9\u30b3\u30a2\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002\u3064\u307e\u308a\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n

\n
\n
\n

\u7a7a\u8179\u6642\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5897\u52a0\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u5897\u52a0\u306f\u8a8d\u77e5\u6a5f\u80fd\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u306e\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u3059\u3079\u3066\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n

\u4e16\u754c\u7684\u306b\u8a8d\u77e5\u75c7\u304c\u554f\u984c\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u307b\u3068\u3093\u3069\u52b9\u679c\u306e\u306a\u3044\u85ac\u306e\u51e6\u65b9\u306e\u524d\u306b\u307e\u305a\u306f\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002\u8a8d\u77e5\u75c7\u306f\u3059\u3050\u306b\u8d77\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u309320\u5e74\u307b\u3069\u3067\u767a\u75c7\u3059\u308b\u3053\u3068\u3092\u8003\u3048\u308c\u3070\u300140\u6b73\u3092\u904e\u304e\u305f\u3089\u7cd6\u8cea\u5236\u9650\u3092\u59cb\u3081\u308b\u3079\u304d\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u3082\u3063\u3068\u65e9\u304f\u3084\u3063\u305f\u65b9\u304c\u826f\u3044\u3067\u3059\u3002<\/p>\n

\u591a\u304f\u306e\u4eba\u306f\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u3053\u3068\u3092\u6c17\u306b\u3059\u308b\u306e\u306b\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002\u672c\u6c17\u3067\u6c17\u306b\u3059\u308b\u306e\u3067\u3042\u308c\u3070\u7cd6\u8cea\u306f\u6442\u3089\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n<\/div>\n

\u300cHyperinsulinemia and cognitive decline in a middle-aged cohort\u300d<\/span><\/p>\n

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