{"id":23550,"date":"2023-10-20T11:45:59","date_gmt":"2023-10-20T02:45:59","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=23550"},"modified":"2023-10-20T11:46:32","modified_gmt":"2023-10-20T02:46:32","slug":"%e3%83%aa%e3%83%aa%e3%82%ab%e3%81%a8%e8%aa%8d%e7%9f%a5%e7%97%87","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=23550","title":{"rendered":"\u30ea\u30ea\u30ab\uff08\u30d7\u30ec\u30ac\u30d0\u30ea\u30f3\uff09\u3068\u8a8d\u77e5\u75c7"},"content":{"rendered":"<p>\u30ea\u30ea\u30ab\u306f\u975e\u5e38\u306b\u5b89\u6613\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672b\u68a2\u306e\u795e\u7d4c\u969c\u5bb3\u6027\u306e\u75db\u307f\u306b\u5bfe\u3057\u3066\u4f7f\u308f\u308c\u308b\u306e\u3067\u3059\u304c\u3001\u4f55\u3067\u3082\u304b\u3093\u3067\u3082\u75db\u307f\u304c\u3042\u308c\u3070NSAIDs\u306e\u6b21\u306b\u30ea\u30ea\u30ab\u3092\u8a66\u3059\u533b\u5e2b\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002\u305d\u3057\u3066\u3001\u3053\u306e\u30ea\u30ea\u30ab\u304c\u9069\u5fdc\u3068\u3055\u308c\u308b\u60a3\u8005\u306e\u591a\u304f\u306f\u9ad8\u9f62\u8005\u3067\u3059\u3002<\/p>\n<p>\u9ad8\u9f62\u8005\u306b\u30ea\u30ea\u30ab\u3092\u51e6\u65b9\u3059\u308b\u3068\u3001\u6642\u306b\u7720\u6c17\u3084\u3075\u3089\u3064\u304d\u304c\u51fa\u307e\u3059\u3002\u305f\u3060\u3067\u3055\u3048\u6b69\u884c\u304c\u5f31\u3063\u3066\u3044\u308b\u9ad8\u9f62\u8005\u304c\u3075\u3089\u3064\u3044\u305f\u3089\u8ee2\u5012\u306e\u6050\u308c\u304c\u3042\u308a\u307e\u3059\u3002\u7720\u6c17\u306a\u3069\u3067\u6d3b\u52d5\u6027\u304c\u4f4e\u4e0b\u3057\u3066\u3057\u307e\u3048\u3070\u3001\u9ad8\u9f62\u8005\u306f\u3069\u3093\u3069\u3093\u5f31\u308a\u307e\u3059\u3002<\/p>\n<p>\u5f53\u7136\u3001\u30ea\u30ea\u30ab\u306f\u4e2d\u67a2\u306b\u4f5c\u7528\u3059\u308b\u306e\u3067\u8a8d\u77e5\u75c7\u3068\u306e\u95a2\u9023\u3092\u8003\u3048\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30ea\u30ea\u30ab\u3068\u8a8d\u77e5\u75c7\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u5206\u6790\u3057\u307e\u3057\u305f\u300234,467\u4eba\u306e\u30ea\u30ea\u30ab\uff08\u307e\u305f\u306f\u30ac\u30d0\u30da\u30f3\u30c1\u30f3\uff09\u304c\u51e6\u65b9\u3055\u308c\u305f\u75c7\u4f8b\u3068172,335\u4eba\u306e\u5bfe\u7167\u304c\u5bfe\u8c61\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"24153\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=24153\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?fit=675%2C677&amp;ssl=1\" data-orig-size=\"675,677\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u30ea\u30ea\u30abfphar-14-1128601-g002\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?fit=300%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?fit=640%2C642&amp;ssl=1\" class=\"alignnone size-full wp-image-24153\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?resize=640%2C642\" alt=\"\" width=\"640\" height=\"642\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?w=675&amp;ssl=1 675w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/3a3afb770fb9edad7019ef5e0aada21c.jpg?resize=150%2C150&amp;ssl=1 150w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u8a8d\u77e5\u75c7\u306e\u7d2f\u7a4d\u767a\u75c7\u7387\u3067\u3059\u3002\u8d64\u304c\u30ea\u30ea\u30ab\u307e\u305f\u306f\u30ac\u30d0\u30da\u30f3\u30c1\u30f3\u3092\u98f2\u3093\u3067\u3044\u308b\u7fa4\u3001\u9752\u306f\u98f2\u3093\u3067\u3044\u306a\u3044\u7fa4\u3067\u3059\u3002\u30ea\u30ea\u30ab\u7fa4\u306e\u65b9\u304c\u8a8d\u77e5\u75c7\u767a\u75c7\u7387\u304c\u9ad8\u3044\u3067\u3059\u306d\u3002<\/p>\n<div class=\"caption\">\n<p>\u3055\u3089\u306b\u4e0b\u306e\u8868\u306e\u3088\u3046\u306b\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u306f\u3001\u8ffd\u8de1\u8abf\u67fb\u4e2d\u306b\u5e74\u9593\u306e\u7d2f\u7a4d\u898f\u5b9a\u7528\u91cf\uff08cDDD\uff09\u304c\u5897\u52a0\u3059\u308b\u306b\u3064\u308c\u3066\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\uff08\u7d2f\u7a4d\u898f\u5b9a\u7528\u91cf\u306b\u3064\u3044\u3066\u306f\u7701\u7565\u3057\u307e\u3059\uff09<\/p>\n<\/div>\n<div class=\"xtable\">\n<table class=\"rendered small default_table\" style=\"width: 93.2602%;\" frame=\"hsides\" rules=\"groups\">\n<thead valign=\"top\">\n<tr>\n<th style=\"width: 74.3725%;\" align=\"left\"><\/th>\n<th style=\"width: 25.4954%;\" align=\"center\">HR (95% CI)<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 74.3725%;\" align=\"left\">\u8ffd\u8de1\u8abf\u67fb\u4e2d\u306e\u5e74\u9593\u306e\u30ac\u30d0\u30da\u30f3\u30c1\u30f3\u307e\u305f\u306f\u30d7\u30ec\u30ac\u30d0\u30ea\u30f3\u306e\u7d2f\u7a4d\u898f\u5b9a\u7528\u91cf<\/th>\n<th style=\"width: 25.4954%;\" align=\"left\"><\/th>\n<\/tr>\n<\/thead>\n<tbody valign=\"top\">\n<tr>\n<td style=\"width: 74.3725%;\" align=\"left\">&lt;0.50<\/td>\n<td style=\"width: 25.4954%;\" align=\"left\">1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 74.3725%;\" align=\"left\">0.50\uff5e1.95<\/td>\n<td style=\"width: 25.4954%;\" align=\"left\"><span style=\"color: #ff0000;\">1.24 (1.09 \uff5e 1.41)<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 74.3725%;\" align=\"left\">1.96\uff5e9.66<\/td>\n<td style=\"width: 25.4954%;\" align=\"left\"><span style=\"color: #ff0000;\">1.69 (1.50\u20131.92)<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 74.3725%;\" align=\"left\">&gt;9.66<\/td>\n<td style=\"width: 25.4954%;\" align=\"left\"><span style=\"color: #ff0000;\">2.44 (2.14 \uff5e 2.78)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u51e6\u65b9\u91cf\u304c\u5897\u52a0\u3059\u308c\u3070\u3059\u308b\u307b\u3069\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"24154\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=24154\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?fit=699%2C557&amp;ssl=1\" data-orig-size=\"699,557\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u30ea\u30ea\u30abfphar-14-1128601-g003\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?fit=300%2C239&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?fit=640%2C510&amp;ssl=1\" class=\"alignnone size-full wp-image-24154\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?resize=640%2C510\" alt=\"\" width=\"640\" height=\"510\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?w=699&amp;ssl=1 699w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/49f589b700797dccfcf82853cd796338.jpg?resize=300%2C239&amp;ssl=1 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u69d8\u3005\u306a\u30b0\u30eb\u30fc\u30d7\u306e\u8a8d\u77e5\u75c7\u767a\u75c7\u30ea\u30b9\u30af\u3067\u3059\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u5e74\u9f62\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u5206\u3051\u308b\u3068\u300150\u6b73\u672a\u6e80\u306e\u65b9\u304c\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u300250\u6b73\u672a\u6e80\u306e\u5e74\u9f62\u30b0\u30eb\u30fc\u30d7\u3067\u306f3.16\u500d\u300150\uff5e59\u6b73\u3067\u306f1.58\u500d\u3001 60\uff5e69\u6b73\u30671.54\u500d\u300170\u6b73\u4ee5\u4e0a\u3067\u306f1.30\u500d\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u5e74\u9f62\u3060\u3051\u3067\u306a\u304f\u305d\u306e\u4ed6\u306e\u69d8\u3005\u306a\u6761\u4ef6\u3067\u306e\u30b0\u30eb\u30fc\u30d7\u306e\u307b\u3068\u3093\u3069\u304c\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u306e\u7d50\u679c\u3092\u8003\u3048\u308b\u3068\u3001\u30ea\u30ea\u30ab\u306e\u9577\u671f\u6295\u4e0e\u30011\u65e5\u91cf\u304c\u591a\u3044\u51e6\u65b9\u3001\u6bd4\u8f03\u7684\u82e5\u5e74\u5c64\u3078\u306e\u6295\u4e0e\u306b\u306f\u614e\u91cd\u306b\u306a\u3089\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3057\u3001\u60a3\u8005\u3078\u306e\u8aac\u660e\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u30ea\u30ea\u30ab\u3082\u6839\u672c\u7684\u306b\u6cbb\u7642\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5fc5\u8981\u6700\u5c0f\u9650\u3067\u3001\u9069\u5fdc\u306e\u7121\u3044\u5834\u5408\u306f\u614e\u91cd\u306b\u691c\u8a0e\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002\u79c1\u306f\u30ea\u30ea\u30ab\u306e\u51e6\u65b9\u306f\u6ec5\u591a\u306b\u3057\u307e\u305b\u3093\u3002<\/p>\n<p>\u305d\u308c\u306b\u30ea\u30ea\u30ab\u306f\u60aa\u540d\u9ad8\u3044\u30d5\u30a1\u30a4\u30b6\u30fc\u306e\u85ac\u3067\u3059\u304b\u3089\u306d\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cThe association between Gabapentin or Pregabalin use and the risk of dementia: an analysis of the National Health Insurance Research Database in Taiwan\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u30ac\u30d0\u30da\u30f3\u30c1\u30f3\u307e\u305f\u306f\u30d7\u30ec\u30ac\u30d0\u30ea\u30f3\u306e\u4f7f\u7528\u3068\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u6027\uff1a\u53f0\u6e7e\u306e\u56fd\u6c11\u5065\u5eb7\u4fdd\u967a\u7814\u7a76\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306e\u5206\u6790\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37324474\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30ea\u30ea\u30ab\u306f\u975e\u5e38\u306b\u5b89\u6613\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672b\u68a2\u306e\u795e\u7d4c\u969c\u5bb3\u6027\u306e\u75db\u307f\u306b\u5bfe\u3057\u3066\u4f7f\u308f\u308c\u308b\u306e\u3067\u3059\u304c\u3001\u4f55\u3067\u3082\u304b\u3093\u3067\u3082\u75db\u307f\u304c\u3042\u308c\u3070NSAIDs\u306e\u6b21\u306b\u30ea\u30ea\u30ab\u3092\u8a66\u3059\u533b\u5e2b\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002\u305d\u3057\u3066\u3001\u3053\u306e\u30ea\u30ea\u30ab\u304c\u9069\u5fdc\u3068\u3055\u308c\u308b\u60a3\u8005\u306e\u591a\u304f\u306f\u9ad8\u9f62\u8005\u3067\u3059\u3002 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