{"id":24238,"date":"2023-10-31T21:35:18","date_gmt":"2023-10-31T12:35:18","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=24238"},"modified":"2023-10-31T21:35:18","modified_gmt":"2023-10-31T12:35:18","slug":"%e6%96%b0%e3%81%97%e3%81%84%e6%9b%b4%e5%b9%b4%e6%9c%9f%e9%9a%9c%e5%ae%b3%e3%81%ae%e8%96%ac%e3%81%a7%e3%81%8c%e3%82%93%e3%81%ab%e3%81%aa%e3%82%8b%e3%81%8b%e3%82%82%e3%81%97%e3%82%8c%e3%81%aa%e3%81%84","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=24238","title":{"rendered":"\u65b0\u3057\u3044\u66f4\u5e74\u671f\u969c\u5bb3\u306e\u85ac\u3067\u304c\u3093\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u306a\u3044"},"content":{"rendered":"

\u4eca\u5e74\uff082023\u5e74\uff09\u306e5\u6708\u306b\u30a2\u30b9\u30c6\u30e9\u30b9\u88fd\u85ac\u304c\u958b\u767a\u3057\u3066\u3044\u305f\u66f4\u5e74\u671f\u969c\u5bb3\u306e\u85ac\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u304c\u30a2\u30e1\u30ea\u30ab\u3067\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u9854\u306e\u307b\u3066\u308a\u3001\u306e\u307c\u305b\u611f\u3001\u5bdd\u6c57\u306a\u3069\u306e\u66f4\u5e74\u671f\u969c\u5bb3\u75c7\u72b6\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u305d\u3046\u3067\u3059\u3002\u3044\u304b\u306b\u3082\u58f2\u308c\u305d\u3046\u306a\u85ac\u3067\u3059\u306d\u3002<\/p>\n

\u3067\u306f\u5b9f\u969b\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\u7b2c3\u76f8\u8a66\u9a13\u3067\u3059\u3002\u5bfe\u8c61\u306f40\uff5e65\u6b73\u3067\u9589\u7d4c\u3068\u78ba\u8a8d\u3055\u308c\u3001\u4e2d\u7b49\u5ea6\uff5e\u91cd\u5ea6\u306eVMS\uff08\u307b\u3066\u308a\u306a\u3069\u3092\u7279\u5fb4\u3068\u3059\u308b\u8840\u7ba1\u904b\u52d5\u795e\u7d4c\u75c7\u72b6\uff09\u304c1\u65e5\u5e73\u57477\u4ef6\u4ee5\u4e0a\u306e\u5973\u6027500\u4eba\u3067\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u7fa4\u300145mg\u7fa4\u306b\u5206\u3051\u3089\u308c\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306fVMS\u306e1\u65e5\u306e\u983b\u5ea6\u3068\u91cd\u75c7\u5ea6\u306e\u5909\u5316\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u30d7\u30e9\u30bb\u30dc\u306f12\u9031\u307e\u3067\u3067\u3059\u3002\u305d\u308c\u4ee5\u964d\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u306b\u3082\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u304c\u6295\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305a\u3001\u8208\u5473\u6df1\u3044\u306e\u306f\u30d7\u30e9\u30bb\u30dc\u52b9\u679c\u3067\u3059\u3002VMS\u306e\u983b\u5ea6\u306e\u5e73\u5747\u5909\u5316\u7387\u306f12\u9031\u3067\u3001\u30d7\u30e9\u30bb\u30dc\u3067\u306f45.35%\u6e1b\u5c11\u3067\u3057\u305f\u3002\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u306758.64%\u6e1b\u5c11\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c845mg\u306764.27%\u6e1b\u5c11\u3060\u3063\u305f\u306e\u3067\u3001\u85ac\u306e\u52b9\u679c\u306f10\u6570\uff05\uff5e20\uff05\u7a0b\u5ea6\u3067\u3059\u306d\u3002<\/p>\n

\u30b0\u30e9\u30d5\u3092\u898b\u308b\u306812\u9031\u4ee5\u964d\u3067\u3055\u3089\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u306e\u3067\u3001\u3082\u3046\u5c11\u3057\u85ac\u306e\u52b9\u679c\u306f\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u4e0a\u306e\u56f3\u306e\u4e0b\u5074\u306e\u56f3\u306e\u91cd\u75c7\u5ea6\u306b\u95a2\u3057\u3066\u3082\u300112\u9031\u3067\u30d7\u30e9\u30bb\u30dc\u3067\u306f\u304a\u3088\u305d20\uff05\u6e1b\u5c11\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u306726\uff05\u6e1b\u5c11\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c845mg\u306732\uff05\u6e1b\u5c11\u3067\u3059\u306e\u3067\u3001\u85ac\u306e\u52b9\u679c\u306f\u305d\u3053\u307e\u3067\u3067\u306f\u306a\u3055\u305d\u3046\u3067\u3059\u306d\u3002\u91cd\u75c7\u5ea6\u308212\u9031\u4ee5\u964d\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u306e\u3067\u3082\u3046\u3061\u3087\u3063\u3068\u52b9\u679c\u306f\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u7761\u7720\u969c\u5bb3\u306e\u30b9\u30b3\u30a2\u306ePROMIS SD SF 8b\u306f8\uff5e40\u70b9\u306e\u7bc4\u56f2\u3067\u6570\u5024\u304c\u5927\u304d\u3044\u307b\u3069\u91cd\u75c7\u3067\u3059\u3002\u305d\u306e\u7761\u7720\u969c\u5bb3\u306e\u30b9\u30b3\u30a2\u306f30mg\u7fa4\u3067\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6709\u610f\u5dee\u306a\u304f\u300145mg\u7fa4\u3067\u306f\u6709\u610f\u5dee\u304c\u51fa\u307e\u3057\u305f\u304c\u3001\u5927\u304d\u306a\u5dee\u306b\u306f\u898b\u3048\u307e\u305b\u3093\u3002\uff08\u8a73\u7d30\u7701\u7565\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u9031\u3054\u3068\u306e24\u6642\u9593\u3042\u305f\u308a\u306e\u4e2d\u7b49\u5ea6\u304a\u3088\u3073\u91cd\u5ea6\u306eVMS\u306e\u983b\u5ea6\u304c50\uff05\u4ee5\u4e0a\u304a\u3088\u307375\uff05\u4ee5\u4e0a\u6e1b\u5c11\u3057\u305f\u5272\u5408\u3067\u3059\u300212\u9031\u76ee\u307e\u3067\u306bVMS\u983b\u5ea6\u306e\u5c11\u306a\u304f\u3068\u308250\uff05\u6e1b\u5c11\u3092\u9054\u6210\u3057\u305f\u53c2\u52a0\u8005\u306e\u5272\u5408\u306f\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u7fa4\u306750.6\uff05\u300145mg\u7fa4\u306760.5\uff05\u3067\u3042\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f42.5\uff05\u3067\u3057\u305f\u3002\u30d7\u30e9\u30bb\u30dc\u52b9\u679c\u304b\u306a\u308a\u3042\u308a\u307e\u3059\u306d\u3002<\/p>\n

\u307e\u3042\u3001\u305d\u308c\u306a\u308a\u306b\u306f\u52b9\u679c\u306f\u3042\u308a\u305d\u3046\u3067\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u30a2\u30b8\u30a2\u4eba\u3067\u306f\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u4e2d\u56fd\u3084\u97d3\u56fd\u3001\u53f0\u6e7e\u3067\u306e300\u4eba\u898f\u6a21\u306e\u6cbb\u9a13\u306f\u3001\u4e8b\u524d\u306b\u8a2d\u5b9a\u3057\u305f\u6709\u52b9\u6027\u306e\u8a55\u4fa1\u9805\u76ee\u3092\u9054\u6210\u3067\u304d\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u3002\uff08\u3053\u306e\u8a18\u4e8b<\/a>\u53c2\u7167\uff09\u4f55\u304c\u9055\u3046\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u79c1\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u7a0b\u5ea6\u306e\u9055\u3044\u304c\u5927\u304d\u3044\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u3057\u3066\u3001\u3053\u306e\u8a18\u4e8b<\/a>\u3067\u306f\u300c\u30a2\u30b9\u30c6\u30e9\u30b9\u306f\u65e5\u672c\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c3\u76f8\u81e8\u5e8a\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u306a\u3044\u3002\u3053\u306e\u72b6\u6cc1\u3067\u3001\u5de8\u984d\u306e\u8cc7\u91d1\u3092\u6295\u3058\u3001\u65e5\u672c\u3067\u306e\u6cbb\u9a13\u3092\u9032\u3081\u308b\u306e\u306b\u8e8a\u8e87\u3057\u3066\u3044\u308b\u306e\u3060\u308d\u3046\u3002\u6211\u304c\u56fd\u521d\u306e\u4e16\u754c\u7684\u306a\u5049\u696d\u304c\u57cb\u3082\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u300d\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u3067\u306f\u6cbb\u9a13\u3092\u884c\u3063\u3066\u3044\u306a\u3044\u3088\u3046\u3067\u3059\u3002\u3067\u3082\u3001\u30a2\u30b8\u30a2\u4eba\u3067\u52b9\u679c\u304c\u306f\u3063\u304d\u308a\u3057\u306a\u3044\u306e\u3067\u3001\u300c\u6211\u304c\u56fd\u521d\u306e\u4e16\u754c\u7684\u306a\u5049\u696d\u304c\u57cb\u3082\u308c\u308b\u300d\u3063\u3066\u3044\u3046\u306e\u3082\u304a\u304b\u3057\u306a\u8a71\u3067\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u4e00\u756a\u91cd\u8981\u306a\u306e\u306f\u5b89\u5168\u6027\u3067\u3059\u3002<\/p>\n

\u6b21\u306e\u8ad6\u6587\u3092\u898b\u305f\u3089\u3001\u307f\u3093\u306a\u8e8a\u8e87\u3059\u308b\u3067\u3057\u3087\u3046\u3002\u4e0b\u306e\u8868\u306f\u65b0\u751f\u7269\u75c7\u4f8b\u306e\u4ef6\u6570\u3068\u65b0\u751f\u7269\u767a\u75c7\u306e\u53ef\u80fd\u6027\u3067\u3059\u3002\u65b0\u751f\u7269\uff08\u816b\u760d\uff09\u306f\u826f\u6027\u3068\u60aa\u6027\u304c\u3042\u308a\u3001\u60aa\u6027\u306f\u3044\u308f\u3086\u308b\u304c\u3093\u3067\u3059\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u30d7\u30e9\u30bb\u30dc<\/strong><\/th>\n\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8 30 mg<\/strong><\/th>\n\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8 45 mg<\/strong><\/th>\n\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u3059\u3079\u3066<\/strong><\/th>\n<\/tr>\n<\/thead>\n
\u30b9\u30ab\u30a4\u30e9\u30a4\u30c8 1 (<\/strong>\u00a0NCT04003155\u00a0)<\/strong><\/td>\n<\/tr>\n
12\u9031\u9593<\/td>\n0\/175<\/td>\n0\/174<\/td>\n3\/173 (1\u00b773%)<\/td>\n3\/347 (0\u00b786%)<\/td>\n<\/tr>\n
52\u9031\u9593<\/td>\n–<\/td>\n1\/76 (1\u00b732%)<\/td>\n1\/76 (1\u00b732%)<\/td>\n2\/152 (1\u00b732%)<\/td>\n<\/tr>\n
\u30b9\u30ab\u30a4\u30e9\u30a4\u30c8 2 (<\/strong>\u00a0NCT04003142\u00a0)<\/strong><\/td>\n<\/tr>\n
12\u9031\u9593<\/td>\n0\/167<\/td>\n0\/166<\/td>\n2\/167 (1\u00b720%)<\/td>\n2\/333 (0\u00b760%)<\/td>\n<\/tr>\n
52\u9031\u9593<\/td>\n–<\/td>\n1\/76 (1\u00b732%)<\/td>\n1\/75 (1\u00b733%)<\/td>\n2\/151 (1\u00b732%)<\/td>\n<\/tr>\n
\u30b9\u30ab\u30a4\u30e9\u30a4\u30c8 4 (<\/strong>\u00a0NCT04003389\u00a0)<\/strong><\/td>\n<\/tr>\n
52\u9031\u9593<\/td>\n2\/610 (0\u00b733%)<\/td>\n5\/611 (0\u00b782%)<\/td>\n9\/609 (1\u00b748%)<\/td>\n14\/1220 (1\u00b715%)<\/td>\n<\/tr>\n
12\u9031\u9593\u307e\u3067\u306e\u30e1\u30bf\u5206\u6790<\/strong><\/td>\n<\/tr>\n
\u75c7\u4f8b\u6570 (%)<\/td>\n2\/952 (0\u30fb21%)<\/td>\n5\/951 (0\u00b753%)<\/td>\n14\/949 (1\u00b748%)<\/td>\n19\/1900 (1\u00b700%)<\/td>\n<\/tr>\n
OR (95% CI)<\/td>\n–<\/td>\n2\u00b736 (0\u00b753\u201310\u00b743)<\/td>\n4\u00b755<\/span> (1\u00b770\u201312\u00b715)<\/td>\n2\u00b794<\/span> (1\u00b718\u20137\u00b732)<\/td>\n<\/tr>\n
52\u9031\u9593\u307e\u3067\u306e\u30e1\u30bf\u5206\u6790<\/strong><\/td>\n<\/tr>\n
\u75c7\u4f8b\u6570 (%)<\/td>\n2\/952 (0\u30fb21%)<\/td>\n7\/1103 (0\u00b764%)<\/td>\n16\/1100 (1\u00b746%)<\/td>\n23\/2203 (1\u00b704%)<\/td>\n<\/tr>\n
OR (95% CI)<\/td>\n–<\/td>\n2\u00b783 (0\u00b776\u201310\u00b754)<\/td>\n4\u00b725<\/span> (1\u00b767\u201310\u00b780)<\/td>\n2\u00b794<\/span> (1\u00b725\u20136\u00b793)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306f\u65b0\u751f\u7269\u767a\u75c7\u306e\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u65b0\u751f\u7269\u75c7\u4f8b\u306f12\u9031\u9593\u3067\u30d7\u30e9\u30bb\u30dc\u3067\u306f2\u4eba\u3067\u3057\u305f\u3002\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u7fa4\u30675\u4eba\u300145mg\u7fa4\u306714\u4eba\u3067\u3057\u305f\u300252\u9031\u307e\u3067\u3067\u306f\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c830mg\u7fa47\u4eba\u300145mg\u7fa423\u4eba\u3067\u3057\u305f\u3002\u65b0\u751f\u7269\u767a\u75c7\u306e\u53ef\u80fd\u6027\u306f45mg\u7fa4\u3067\u6709\u610f\u306712\u9031\u30674.55\u500d\u300152\u9031\u30674.25\u500d\u3002\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u5168\u4f53\u3067\u30822.94\u500d\u3067\u3057\u305f\u3002<\/p>\n

\u8a66\u9a13\u5168\u4f53\u3067\u691c\u7d22\u3055\u308c\u305f25\u4f8b\u306e\u3046\u30613\u4f8b (12.00%) \u306f\u826f\u6027\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u7fa4\u306e24\u4eba\u3067\u5831\u544a\u3055\u308c\u305f26\u4ef6\u306e\u65b0\u751f\u7269\u306e\u3046\u306113\u4ef6 (50.00%) \u306f\u3001\u76ae\u819a\u307e\u305f\u306f\u7c98\u819c\u304b\u3089\u306e\u65b0\u751f\u7269\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u3002\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u30671\uff05\u3082\u306e\u4eba\u304c\u826f\u6027\u304b\u60aa\u6027\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u816b\u760d\u304c\u3067\u304d\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n

\u826f\u6027\u306f\u305f\u3063\u305f12\uff05\u3067\u3001\u4ed6\u306f\u60aa\u6027\u3068\u306f\u66f8\u304b\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u60aa\u6027\u3067\u3057\u3087\u3046\u3002\u304a\u3088\u305d3\u500d\u3082\u306e\u304c\u3093\u307e\u305f\u306f\u826f\u6027\u816b\u760d\u304c\u5897\u52a0\u3059\u308b\u53ef\u80fd\u6027\u3092\u6301\u3063\u305f\u85ac\u304c\u7c21\u5358\u306b\u627f\u8a8d\u3055\u308c\u308b\u6642\u4ee3\u3067\u3059\u3002\u4e16\u306e\u4e2d\u72c2\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3082\u3084\u85ac\u5bb3\u306e\u5302\u3044\u304c\u3057\u307e\u3059\u3002<\/p>\n

\u65e5\u672c\u3067\u306f\u6cbb\u9a13\u3082\u8ca9\u58f2\u3082\u5fc5\u8981\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u300cEfficacy and Safety of Fezolinetant in Moderate to Severe Vasomotor Symptoms Associated With Menopause: A Phase 3 RCT\u300d<\/span><\/p>\n

\u300c\u9589\u7d4c\u306b\u4f34\u3046\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u8840\u7ba1\u904b\u52d5\u75c7\u72b6\u306b\u304a\u3051\u308b\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\uff1a\u7b2c3\u76f8RCT\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u300cRisk of neoplasm with the neurokinin 3 receptor antagonist fezolinetant\u300d<\/span><\/p>\n

\u300c\u30cb\u30e5\u30fc\u30ed\u30ad\u30cb\u30f3 3 \u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u306b\u3088\u308b\u65b0\u751f\u7269\u306e\u30ea\u30b9\u30af\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u4eca\u5e74\uff082023\u5e74\uff09\u306e5\u6708\u306b\u30a2\u30b9\u30c6\u30e9\u30b9\u88fd\u85ac\u304c\u958b\u767a\u3057\u3066\u3044\u305f\u66f4\u5e74\u671f\u969c\u5bb3\u306e\u85ac\u3001\u30d5\u30a7\u30be\u30ea\u30cd\u30bf\u30f3\u30c8\u304c\u30a2\u30e1\u30ea\u30ab\u3067\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u9854\u306e\u307b\u3066\u308a\u3001\u306e\u307c\u305b\u611f\u3001\u5bdd\u6c57\u306a\u3069\u306e\u66f4\u5e74\u671f\u969c\u5bb3\u75c7\u72b6\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u305d\u3046\u3067\u3059\u3002\u3044\u304b\u306b\u3082\u58f2\u308c\u305d\u3046\u306a\u85ac\u3067\u3059\u306d\u3002 \u3067\u306f\u5b9f\u969b<\/p>\n","protected":false},"author":1,"featured_media":24264,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[153],"tags":[45,58,218],"class_list":["post-24238","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-side","tag-cancer","tag-218","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/10\/26844301_s.jpg?fit=640%2C427&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-6iW","jetpack-related-posts":[{"id":28730,"url":"https:\/\/promea2014.com\/blog\/?p=28730","url_meta":{"origin":24238,"position":0},"title":"\u4e73\u304c\u3093\u60a3\u8005\u306e\u30db\u30c3\u30c8\u30d5\u30e9\u30c3\u30b7\u30e5\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306e\u30de\u30b0\u30cd\u30b7\u30a6\u30e0","author":"Dr.Shimizu","date":"2025\u5e741\u670821\u65e5","format":false,"excerpt":"\u4e73\u304c\u3093\u60a3\u8005\u306f\u3001\u305d\u306e\u5f8c\u306e\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u306b\u3088\u308a\u3001\u6bd4\u8f03\u7684\u9ad8\u983b\u5ea6\u306b\u4e0d\u5feb\u306a\u30db\u30c3\u30c8\u30d5\u30e9\u30c3\u30b7\u30e5\uff08\u307b\u3066\u308a\uff09\u3092\u611f\u3058\u307e\u3059\u3002\u2026","rel":"","context":"\u304c\u3093","block_context":{"text":"\u304c\u3093","link":"https:\/\/promea2014.com\/blog\/?cat=153"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/01\/3257899_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/01\/3257899_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/01\/3257899_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":521,"url":"https:\/\/promea2014.com\/blog\/?p=521","url_meta":{"origin":24238,"position":1},"title":"\u30b5\u30a4\u30f3\u30d0\u30eb\u30bf\u6162\u6027\u8170\u75db\u75c7\u306b\u9069\u5fdc\u62e1\u5927","author":"Dr.Shimizu","date":"2016\u5e743\u670831\u65e5","format":false,"excerpt":"\u6297\u3046\u3064\u85ac\u306e\u30b5\u30a4\u30f3\u30d0\u30eb\u30bf\u306e\u9069\u5fdc\u306b\u6162\u6027\u8170\u75db\u75c7\u304c\u8ffd\u52a0\u3055\u308c\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u539a\u751f\u52b4\u50cd\u7701\u304b\u3089\u3059\u3050\u306b\u304a\u9054\u3057\u304c\u6765\u307e\u3057\u2026","rel":"","context":"\u75c5\u6c17","block_context":{"text":"\u75c5\u6c17","link":"https:\/\/promea2014.com\/blog\/?cat=15"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2016\/03\/GTY0027883401.jpg?fit=338%2C506&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":20891,"url":"https:\/\/promea2014.com\/blog\/?p=20891","url_meta":{"origin":24238,"position":2},"title":"\u300c\u6297\u80a5\u6e80\u85ac\u300d\u30aa\u30eb\u30ea\u30b9\u30bf\u30c3\u30c8\u304c\u51e6\u65b9\u7b8b\u306a\u3057\u306b\u85ac\u5c40\u3067\u8cfc\u5165\u53ef\u80fd\u306b\u306a\u308b\u3088\u3046\u3067\u3059","author":"Dr.Shimizu","date":"2022\u5e7412\u67081\u65e5","format":false,"excerpt":"\u6297\u80a5\u6e80\u85ac\u3067\u3042\u308b\u30aa\u30eb\u30ea\u30b9\u30bf\u30c3\u30c8\uff08\u5546\u54c1\u540d\u30a2\u30e9\u30a4\uff09\u304c\u3001\u6765\u5e742023\u5e743\u6708\u3088\u308a\u533b\u5e2b\u306e\u51e6\u65b9\u7b8b\u306a\u3057\u306b\u85ac\u5c40\u3067\u8cb7\u3048\u308b\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/25391676_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/25391676_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/11\/25391676_s.jpg?fit=640%2C480&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":7730,"url":"https:\/\/promea2014.com\/blog\/?p=7730","url_meta":{"origin":24238,"position":3},"title":"\u65b0\u3057\u3044\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u306e\u85ac\u30bf\u30ea\u30fc\u30b8\u30a7\uff08\u30df\u30ed\u30ac\u30d0\u30ea\u30f3\uff09\u306e\u52b9\u679c\u3082\u602a\u3057\u3044","author":"Dr.Shimizu","date":"2019\u5e744\u670812\u65e5","format":false,"excerpt":"\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u3084\u3063\u3071\u308a\u30ea\u30ea\u30ab\u306f\u52b9\u304b\u306a\u3044\u3000\u526f\u4f5c\u7528\u305f\u3063\u3077\u308a\u306e\u79d1\u5b66\u7684\u6839\u62e0\u306e\u306a\u3044\u9069\u5fdc\u75c7\u300d\u3067\u3082\u66f8\u304d\u307e\u3057\u305f\u304c\u3001\u795e\u7d4c\u2026","rel":"","context":"\u75c5\u6c17","block_context":{"text":"\u75c5\u6c17","link":"https:\/\/promea2014.com\/blog\/?cat=15"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/04\/70ab9fc125fd34fb73cfcf08751fff2b_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/04\/70ab9fc125fd34fb73cfcf08751fff2b_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/04\/70ab9fc125fd34fb73cfcf08751fff2b_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":29619,"url":"https:\/\/promea2014.com\/blog\/?p=29619","url_meta":{"origin":24238,"position":4},"title":"\u9ad8\u8840\u5727\u306e\u85ac\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09\u306f\u672c\u5f53\u306b\u5fc5\u8981\u306a\u85ac\u304b\uff1f\u3000\u305d\u306e1","author":"Dr.Shimizu","date":"2025\u5e744\u670825\u65e5","format":false,"excerpt":"\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09\u306f\u9ad8\u8840\u5727\u306e\u85ac\u3067\u3042\u308a\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u814e\u81d3\u3084\u5fc3\u81d3\u3092\u4fdd\u8b77\u3059\u2026","rel":"","context":"\u7cd6\u5c3f\u75c5","block_context":{"text":"\u7cd6\u5c3f\u75c5","link":"https:\/\/promea2014.com\/blog\/?cat=150"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/04\/23260774_s.jpg?fit=640%2C423&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/04\/23260774_s.jpg?fit=640%2C423&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/04\/23260774_s.jpg?fit=640%2C423&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":24696,"url":"https:\/\/promea2014.com\/blog\/?p=24696","url_meta":{"origin":24238,"position":5},"title":"\u52b9\u679c\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u306f\u3084\u3063\u3071\u308a\u3084\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044GIP\/GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac","author":"Dr.Shimizu","date":"2023\u5e7412\u670813\u65e5","format":false,"excerpt":"2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3067\u3059\u304c\u3001\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff08\u5546\u54c1\u540d\uff1a\u30de\u30f3\u30b8\u30e3\u30ed\uff09\u3068\u3044\u2026","rel":"","context":"\u7cd6\u5c3f\u75c5","block_context":{"text":"\u7cd6\u5c3f\u75c5","link":"https:\/\/promea2014.com\/blog\/?cat=150"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/12\/27558739_s.jpg?fit=640%2C482&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/12\/27558739_s.jpg?fit=640%2C482&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/12\/27558739_s.jpg?fit=640%2C482&ssl=1&resize=525%2C300 1.5x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24238"}],"version-history":[{"count":6,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24238\/revisions"}],"predecessor-version":[{"id":24285,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24238\/revisions\/24285"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/media\/24264"}],"wp:attachment":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}