{"id":24247,"date":"2023-11-02T00:20:53","date_gmt":"2023-11-01T15:20:53","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=24247"},"modified":"2023-11-02T00:20:53","modified_gmt":"2023-11-01T15:20:53","slug":"%e3%81%84%e3%81%be%e3%81%a0%e3%81%ab%e7%87%bb%e3%82%8bsglt-2%e9%98%bb%e5%ae%b3%e8%96%ac%e3%81%ae%e4%b8%8b%e8%82%a2%e5%88%87%e6%96%ad%e3%83%aa%e3%82%b9%e3%82%af","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=24247","title":{"rendered":"\u3044\u307e\u3060\u306b\u71fb\u308bSGLT-2\u963b\u5bb3\u85ac\u306e\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af"},"content":{"rendered":"

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85acSGLT2\u963b\u5bb3\u85ac\u306f\u4e0b\u80a2\u5207\u65ad\u3092\u5897\u52a0\u3055\u305b\u308b\u304b\u3082\u3057\u308c\u306a\u3044\uff01<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001SGLT-2\u963b\u5bb3\u85ac\u306b\u306f\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u5897\u52a0\u306e\u61f8\u5ff5\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u305d\u306e\u8ad6\u6587\u306f\u3053\u3053<\/a>\uff09<\/p>\n

CANVAS\u8a66\u9a13\u3068\u8a00\u308f\u308c\u308b\u3082\u306e\u3067\u3001\u5229\u76ca\u76f8\u53cd\u305f\u3063\u3077\u308a\u3067\u3001\u88fd\u85ac\u4f1a\u793e\u304c\u30b9\u30dd\u30f3\u30b5\u30fc\u306b\u306a\u3063\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u304c\u304a\u3088\u305d2\u500d\u306b\u306a\u308b\u7d50\u679c\u306b\u306a\u3063\u305f\u306e\u3067\u3001\u6050\u3089\u304f\u88fd\u85ac\u4f1a\u793e\u306f\u614c\u3066\u305f\u3067\u3057\u3087\u3046\u3002\u305d\u306e\u5f8c\u3044\u304f\u3064\u3082\u306e\u8ad6\u6587\u304c\u51fa\u3066\u304f\u308c\u3070\u3001\u5f53\u7136\u305d\u3053\u3067\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u304c\u884c\u308f\u308c\u308b\u306e\u3067\u3001\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u3092\u8584\u3081\u308b\u305f\u3081\u306e\u30ea\u30b9\u30af\u5897\u52a0\u304c\u306a\u3044\u8ad6\u6587\u304a\u3088\u3073\u30ea\u30b9\u30af\u4f4e\u4e0b\u8ad6\u6587\u3092\u3044\u304f\u3064\u3082\u7528\u610f\u3059\u308c\u3070\u3001\u5206\u6790\u306e\u7d50\u679c\u306f\u30ea\u30b9\u30af\u306a\u3057\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u3057\u304b\u3082\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u305b\u305a\u3001\u4ed6\u306e\u85ac\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3044\u3046\u7814\u7a76\u306b\u3059\u308c\u3070\u3001SGLT-2\u963b\u5bb3\u85ac\u306e\u30ea\u30b9\u30af\u304c\u975e\u5e38\u306b\u5206\u304b\u308a\u3065\u3089\u3044\u3082\u306e\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u4f8b\u3048\u3070\u3053\u306e\u8ad6\u6587\u3002\uff08\u8ad6\u6587\u306f\u3053\u3053<\/a>\u3001\u56f3\u306f\u3053\u306e\u8ad6\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306fSGLT-2\u963b\u5bb3\u85ac\u3068GLP-1\u85ac\u3001DPP-4\u963b\u5bb3\u85ac\u3001\u4ed6\u306e\u7cd6\u5c3f\u75c5\u85ac\u3068\u306e\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u7b49\u306e\u6bd4\u8f03\u3067\u3059\u3002GLP-1\u3068\u306f\u6709\u610f\u306a\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001DPP-4\u963b\u5bb3\u85ac\u3084\u4ed6\u306e\u7cd6\u5c3f\u75c5\u85ac\u3088\u308a\u3082SGLT-2\u963b\u5bb3\u85ac\u306f\u30ea\u30b9\u30af\u4f4e\u4e0b\u3092\u8a8d\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3082\u5229\u76ca\u76f8\u53cd\u30d0\u30ea\u30d0\u30ea\u3067\u3059\u3002<\/p>\n

SGLT-2\u963b\u5bb3\u85ac\u306e\u30ea\u30b9\u30af\u304c\u975e\u5e38\u306b\u5206\u304b\u308a\u3065\u3089\u304f\u306a\u308b\u306e\u306f\u3001\u3069\u306e\u7cd6\u5c3f\u75c5\u85ac\u3082\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u3092\u4e0a\u3052\u3066\u3044\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n

\u4f8b\u3048\u3070\u3042\u308b\u8ad6\u6587\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u3082\u3061\u308d\u3093\u3001\u7d4c\u53e3\u7cd6\u5c3f\u75c5\u85ac\u3067\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u306f\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u3053\u306e\u8ad6\u6587<\/a>\u53c2\u7167\uff09\u98df\u4e8b\u7642\u6cd5\u306e\u307f\u3068\u6bd4\u8f03\u3057\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u4f7f\u7528\u306e2\u578b\u7cd6\u5c3f\u75c5\u30672.41\u500d\u3001\u7d4c\u53e3\u7cd6\u5c3f\u75c5\u85ac\u4f7f\u7528\u306e2\u578b\u7cd6\u5c3f\u75c5\u30671.62\u500d\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f7f\u7528\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u307b\u3069\u7cd6\u5c3f\u75c5\u304c\u60aa\u5316\u3057\u3066\u3044\u305f\u3068\u3082\u8003\u3048\u3089\u308c\u307e\u3059\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f7f\u3046\u307b\u3069\u60aa\u5316\u3059\u308b\u307e\u3067\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u7d9a\u3051\u3001\u305d\u306e\u5f8c\u3082\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u7d9a\u3051\u3001\u3055\u3089\u306b\u8840\u7ba1\u640d\u50b7\u3092\u60aa\u5316\u3055\u305b\u305f\u3068\u3082\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u85ac\u3092\u4f7f\u3046\u3053\u3068\u3067\u3001\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u306f\u4f4e\u4e0b\u3057\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u6700\u8fd1\u3067\u3082\u3084\u306f\u308a\u3001\u3053\u306eSGLT-2\u963b\u5bb3\u85ac\u306e\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u3068\u3044\u3046\u7814\u7a76\u304c\u51fa\u3066\u304d\u3066\u3044\u307e\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n\n\n\n\n\n\n\n
<\/th>\n1\u5e74<\/th>\n2\u5e74<\/th>\n3\u5e74<\/th>\n4\u5e74<\/th>\n<\/tr>\n<\/thead>\n
SGLT2<\/td>\n0.33% (0.17\uff5e0.63%)<\/td>\n0.66% (0.39 \uff5e 1.11%)<\/td>\n1.14% (0.72\uff5e1.80%)<\/td>\n2.15% (1.33\uff5e3.47%)<\/span><\/td>\n<\/tr>\n
DPP-4<\/td>\n0.37% (0.20\uff5e0.69%)<\/td>\n0.70% (0.42\uff5e1.15%)<\/td>\n0.77% (0.47\uff5e1.25%)<\/td>\n0.77% (0.47\uff5e1.25%)<\/span><\/td>\n<\/tr>\n
\u7d2f\u7a4d\u30cf\u30b6\u30fc\u30c9\u6bd4<\/td>\n0.89 (0.36\u20132.20)<\/td>\n0.94 (0.45 \uff5e 1.95)<\/td>\n1.48 (0.76\u20132.91)<\/td>\n2.81 (1.63\u20134.84)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\"\"<\/a><\/p>\n

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\u4e00\u5fdc\u3053\u306e\u7814\u7a76\u3067\u306f\u5229\u76ca\u76f8\u53cd\u306f\u306a\u3055\u305d\u3046\u3067\u3059\u3002<\/p>\n

\u3082\u3061\u308d\u3093\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3053\u308c\u3089\u3092\u307e\u3068\u3081\u308b\u306e\u3067\u3001\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u306e\u3068\u4f4e\u3044\u306e\u304c\u96c6\u3081\u3089\u308c\u308c\u3070\u3001\u95a2\u9023\u306a\u3057\u306e\u7d50\u8ad6\u306b\u306a\u308b\u306e\u306f\u5f53\u7136\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u5b9f\u969b\u306b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u4e0b\u306e\u56f3\u306e\u3088\u3046\u3067\u3059\u3002\uff08\u56f3\u306f\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

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\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u526f\u4f5c\u7528\u306e\u306a\u3044\u85ac\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002\u7cd6\u5c3f\u75c5\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306a\u306e\u3067\u3001\u85ac\u3067\u6cbb\u7642\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u7cd6\u8cea\u5236\u9650\u3092\u3057\u307e\u3057\u3087\u3046\u3002\u305d\u3046\u3059\u308c\u3070\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u306a\u3093\u3066\u8003\u3048\u306a\u304f\u3066\u3082\u3088\u304f\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u3057\u3066\u3001\u7cd6\u5c3f\u75c5\u306e\u6a19\u6e96\u6cbb\u7642\u306e\u5931\u6557\u304c\u4e0b\u80a2\u5207\u65ad\u3092\u62db\u3044\u3066\u3044\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u308c\u306b\u3064\u3044\u3066\u306f\u6b21\u56de\u4ee5\u964d\u3067\u3002<\/p>\n

\u300cRisk of lower extremity amputations in patients with type 2 diabetes using sodium-glucose co-transporter 2 inhibitors\u300d<\/span><\/p>\n

\u300cSGLT-2\u963b\u5bb3\u85ac\u3092\u4f7f\u7528\u3059\u308b2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u4e0b\u80a2\u5207\u65ad\u306e\u30ea\u30b9\u30af\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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