{"id":2427,"date":"2017-08-24T13:00:29","date_gmt":"2017-08-24T04:00:29","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=2427"},"modified":"2017-08-24T13:00:29","modified_gmt":"2017-08-24T04:00:29","slug":"post-2427","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=2427","title":{"rendered":"\u30d3\u30bf\u30df\u30f3\u306f\u5b89\u5168\u3067\u306f\u306a\u3044"},"content":{"rendered":"

\u30d3\u30bf\u30df\u30f3\u306f\u751f\u7269\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u91cd\u8981\u304b\u3064\u5fc5\u9808\u306e\u3082\u306e\u3067\u3042\u308b\u3053\u3068\u306f\u5426\u5b9a\u3057\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u3060\u304b\u3089\u3068\u8a00\u3063\u3066\u305f\u304f\u3055\u3093\u6442\u308c\u3070\u826f\u3044\u3063\u3066\u3082\u3093\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5fc5\u9808\u306e\u6804\u990a\u7d20\uff1d\u5b89\u5168\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u3002\u69d8\u3005\u306a\u591a\u69d8\u306a\u98df\u6750\u3092\u6442\u3063\u3066\u3044\u308c\u3070\u3001\u305d\u3053\u304b\u3089\u5341\u5206\u88dc\u3048\u308b\u306f\u305a\u306e\u6804\u990a\u7d20\u3092\u3001\u6562\u3048\u3066\u5de5\u696d\u88fd\u54c1\u3067\u3042\u308b\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304b\u3089\u6442\u308b\u30ea\u30b9\u30af\u3092\u8003\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u98df\u4e8b\u304b\u3089\u6442\u3063\u3066\u3044\u308b\u6804\u990a\u7d20\u306f\u5c11\u3057\u305a\u3064\u4f53\u306b\u5438\u53ce\u3055\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u6442\u308b\u3068\u3001\u4e00\u6c17\u306b\u5927\u91cf\u306e\u5358\u4f53\u306e\u6804\u990a\u7d20\u304c\u4f53\u306b\u5165\u308b\u306e\u3067\u3001\u4f53\u304c\u98df\u4e8b\u306e\u3068\u304d\u3068\u540c\u3058\u53cd\u5fdc\u3092\u3059\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u305d\u3057\u3066\u3001\u5fc5\u9808\u306e\u3082\u306e\u3068\u306f\u3044\u3048\u3001\u3069\u308c\u3060\u3051\u6442\u308b\u306e\u304c\u9069\u5207\u306a\u91cf\u306a\u306e\u304b\u306f\u306f\u3063\u304d\u308a\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n

\u305d\u3093\u306a\u308f\u304b\u3089\u306a\u3044\u72b6\u614b\u3067\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u63a8\u9032\u3057\u3066\u3044\u308b\u4eba\u305f\u3061\u306b\u3068\u3063\u3066\u3001\u30d3\u30bf\u30df\u30f3B6\u300020mg \/ d\u3001B12\u300055\u03bcg\/ d\u3068\u3044\u3046\u306e\u306f\u30011\u65e5\u306e\u6700\u4f4e\u91cf\u4ee5\u4e0b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u56fd\u306e\u63a8\u5968\u91cf\u306f\u3082\u3063\u3068\u4f4e\u3044\u306e\u3067\u3059\uff08\u30d3\u30bf\u30df\u30f3B6\u30001.2\uff5e1.4mg \/ d\u3001B12\u30002.4\u03bcg\/ d\uff09\u3002\u56fd\u306e\u63a8\u5968\u91cf\u304c\u6b63\u3057\u3044\u3068\u3082\u601d\u3063\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u305d\u306e10\u500d\u3092\u306f\u308b\u304b\u306b\u8d85\u3048\u308b\u91cf\u3092\u65e5\u5e38\u7684\u306b\u6442\u308b\u3053\u3068\u306f\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u4f7f\u7528\u3059\u308b\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u5371\u967a\u6027\u3092\u793a\u3057\u305f\u7814\u7a76\u3067\u3059\u3002<\/p>\n

\u300cLong-Term, Supplemental, One-Carbon Metabolism\u2013Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) Cohort\u300d<\/span><\/p>\n

\u300c\u30d3\u30bf\u30df\u30f3\u304a\u3088\u3073\u751f\u6d3b\u7fd2\u6163\uff08VITAL\uff09\u30b3\u30db\u30fc\u30c8\u306b\u304a\u3051\u308b\u80ba\u764c\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u305f\u9577\u671f\u7684\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3088\u308b\u30011\u70ad\u7d20\u5358\u4f4d\u4ee3\u8b1d\u95a2\u9023\u30d3\u30bf\u30df\u30f3B\u306e\u4f7f\u7528\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u8981\u7d04<\/span>
\n1\u70ad\u7d20\u5358\u4f4d\u4ee3\u8b1d\u95a2\u9023\u306e\u30d3\u30bf\u30df\u30f3B\u306e\u4f7f\u7528\u3068\u80ba\u764c\u30ea\u30b9\u30af\u3068\u306e\u9593\u306b\u95a2\u9023\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u77db\u76fe\u3057\u305f\u77e5\u898b\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3088\u308b\u30d3\u30bf\u30df\u30f3B\u306e\u4f7f\u7528\u7387\u304c\u9ad8\u3044\u305f\u3081\u3001\u53ef\u80fd\u6027\u306e\u3042\u308b\u95a2\u9023\u6027\u306f\u3001\u3055\u3089\u306b\u8abf\u67fb\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u6211\u3005\u306f\u3001\u304c\u3093\u30ea\u30b9\u30af\u3068\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u4f7f\u7528\u306e\u95a2\u9023\u3092\u898b\u308b\u305f\u3081\u306b\u7279\u5225\u306b\u8a2d\u8a08\u3055\u308c\u305f\u30d3\u30bf\u30df\u30f3\u304a\u3088\u3073\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\uff08VITAL\uff09\u30b3\u30db\u30fc\u30c8\u306b\u304a\u3044\u3066\u30011\u70ad\u7d20\u5358\u4f4d\u4ee3\u8b1d\u7d4c\u8def\u306b\u304a\u3051\u308b\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u30d3\u30bf\u30df\u30f3B\u7fa4\u306e\u9577\u671f\u4f7f\u7528\u3068\u80ba\u764c\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u6027\u3092\u691c\u8a0e\u3057\u305f\u3002<\/span>
\n2000\u5e7410\u6708\u304b\u30892002\u5e7412\u6708\u306e\u9593\u306b\u3001VITAL\u30b3\u30db\u30fc\u30c8\u306e\u53c2\u52a0\u8005\u7dcf\u657077,118\u540d\uff0850\u6b73\u304b\u308976\u6b73\uff09\u3092\u5206\u6790\u3057\u305f\u3002\u80ba\u764c\u3092\u767a\u75c7\u3057\u305f\u306e\u306f808\u4eba\u3067\u3042\u3063\u305f\u3002<\/span><\/p>\n

\u7d50\u679c<\/span>
\n\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u30d3\u30bf\u30df\u30f3B6\u3001\u8449\u9178\u5869\u3001\u304a\u3088\u3073B12\u306e\u4f7f\u7528\u306f\u3001\u5973\u6027\u306e\u80ba\u764c\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u3057\u304b\u3057\u3001\u5bfe\u7167\u7684\u306b\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u304b\u3089\u3067\u306f\u306a\u304f\u3001\u500b\u3005\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304b\u3089\u306e\u30d3\u30bf\u30df\u30f3B6\u304a\u3088\u3073B12\u306e\u4f7f\u7528\u306f\u3001\u7537\u6027\u306b\u304a\u3051\u308b\u80ba\u764c\u30ea\u30b9\u30af\u306e30\uff05\u301c40\uff05\u306e\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u300210\u5e74\u9593\u306e\u5e73\u5747\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u91cf\u3092\u8a55\u4fa1\u3059\u308b\u3068\u3001\u30d3\u30bf\u30df\u30f3B6\u304c\u6700\u3082\u591a\u3044\u7fa4\uff0820mg \/ d\u4ee5\u4e0a\uff09\u3001\u30d3\u30bf\u30df\u30f3B12\uff0855\u03bcg\/ d\u4ee5\u4e0a\uff09\u306b\u304a\u3044\u3066\u7537\u6027\u306e\u80ba\u764c\u30ea\u30b9\u30af\u304c\u30d3\u30bf\u30df\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u4f7f\u3063\u3066\u3044\u306a\u3044\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u307b\u307c2\u500d\u306b\u4e0a\u6607\u3057\u305f\u3002\u30d3\u30bf\u30df\u30f3B6\u304a\u3088\u3073B12\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u7fa4\u3067\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306b\u55ab\u7159\u3057\u3066\u3044\u305f\u7537\u6027\u306e\u30ea\u30b9\u30af\u306f\u3055\u3089\u306b\u9ad8\u304f\u3001\u30d3\u30bf\u30df\u30f3B6\u7d043\u500d\u3001\u30d3\u30bf\u30df\u30f3B12\u3067\u7d044\u500d\u3067\u3042\u3063\u305f\u3002\u52a0\u3048\u3066\u3001\u30d3\u30bf\u30df\u30f3B6\u3084B12\u306e\u95a2\u9023\u6027\u306f\u3001\u55ab\u7159\u306b\u3042\u307e\u308a\u95a2\u9023\u3057\u3066\u3044\u306a\u3044\u30bf\u30a4\u30d7\u3067\u3042\u308b\u817a\u764c\u3092\u9664\u304f\u3059\u3079\u3066\u306e\u7d44\u7e54\u578b\u306b\u304a\u3044\u3066\u660e\u3089\u304b\u3060\u3063\u305f\u3002<\/span><\/p>\n

\u7d50\u8ad6<\/span>
\n\u3053\u306e\u6027\u5225\u306b\u3088\u308b\u5dee\u3068\u767a\u751f\u306b\u95a2\u308f\u3063\u3066\u3044\u308b\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u56fa\u6709\u306e\u95a2\u9023\u6027\u306f\u3001\u30d3\u30bf\u30df\u30f3B\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304c\u80ba\u764c\u306b\u5bfe\u3057\u3066\u4e88\u9632\u7684\u3067\u306f\u306a\u304f\u3001\u6709\u5bb3\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3055\u3089\u306a\u308b\u8a3c\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u3002<\/span><\/p>\n

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