{"id":24509,"date":"2023-12-06T12:21:06","date_gmt":"2023-12-06T03:21:06","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=24509"},"modified":"2023-12-06T12:21:06","modified_gmt":"2023-12-06T03:21:06","slug":"%e9%81%8b%e5%8b%95%e3%81%ae%e8%b3%aa%e3%81%a8hdl%e3%81%ae%e8%b3%aa","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=24509","title":{"rendered":"\u904b\u52d5\u306e\u8cea\u3068HDL\u306e\u8cea"},"content":{"rendered":"<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=21106\" target=\"_blank\" 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data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?fit=294%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?fit=640%2C654&amp;ssl=1\" class=\"alignnone size-full wp-image-24511\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?resize=640%2C654\" alt=\"\" width=\"640\" height=\"654\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?w=798&amp;ssl=1 798w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?resize=294%2C300&amp;ssl=1 294w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/25a35da577f587d07fa5895b9d6bbf5c.png?resize=768%2C784&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u3067\u3059\u3002HDL\u306e\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u306b\u306fapoA-\u2160\u3068apoA-\u2161\u304c\u3042\u308a\u307e\u3059\u304c\u3001apoA-II\u306b\u3064\u3044\u3066\u4eca\u307e\u3067\u306b\u308f\u304b\u3063\u3066\u3044\u308b\u5f71\u97ff\u306f\u591a\u304f\u304c\u6709\u5bb3\u3067\u3059\u3002apoA-II \u306f\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u306e\u5897\u52a0\u3001\u4f53\u8102\u80aa\u304c\u5897\u52a0\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u5897\u52a0\u306a\u3069\u3067\u3059\u3002\u3057\u304b\u3057\u4f55\u3089\u304b\u306e\u6709\u76ca\u306a\u4f5c\u7528\u304c\u3042\u308b\u304b\u3089\u3053\u305d\u3001\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u3088\u304f\u308f\u304b\u308a\u307e\u305b\u3093\u3002apoA-\u2161\u306b\u3064\u3044\u3066\u306f\u3044\u3064\u304b\u8a18\u4e8b\u306b\u3057\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>HDL\u306eapoA-\u2161\u306f\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001HDL2\u3067\u306f\u91cd\u91cf\u6319\u3052\u3067\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u4ee5\u5916\u3067\u306f\u5bfe\u7167\u7fa4\u3088\u308a\u4f4e\u4e0b\u3057\u3001\u30e9\u30f3\u30ca\u30fc\u3067\u306f\u30bc\u30ed\u3067\u3059\u3002HDL3\u3067\u306fapoA-\u2161\u306f\u5168\u3066\u3067\u5bfe\u7167\u7fa4\u3088\u308a\u3082\u4f4e\u4e0b\u3057\u3001\u7279\u306b\u30e9\u30f3\u30ca\u30fc\u3068\u30ec\u30b9\u30ea\u30f3\u30b0\u3067\u5927\u304d\u304f\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u6709\u76ca\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308bapoA-\u2160\u306e\u65b9\u306f\u3001HDL2\u3067\u306f\u7279\u306b\u30ec\u30b9\u30ea\u30f3\u30b0\u3067\u5927\u304d\u304f\u5897\u52a0\u3057\u3001\u30e9\u30f3\u30ca\u30fc\u3082\u30cf\u30f3\u30de\u30fc\u6295\u3052\u3067\u3082\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002HDL3\u3067\u306f\u5168\u3066\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u3067apoA-\u2160\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u7279\u306b\u30e9\u30f3\u30ca\u30fc\u3067\u5927\u304d\u304f\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u6b21\u306f\u30ec\u30b9\u30ea\u30f3\u30b0\u3067\u3059\u3002<\/p>\n<p>HDL\u3082LDL\u3068\u540c\u69d8\u306b\u3001\u6570\u5024\u3067\u306f\u306a\u304f\u8cea\u304c\u91cd\u8981\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u6050\u3089\u304f\u3044\u304f\u3089HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u5897\u52a0\u3057\u3066\u3082\u3001apoA-\u2160\/apoA-\u2161\u306e\u6bd4\u304c\u5c0f\u3055\u3044\u3001\u3064\u307e\u308aapoA-\u2161\u304c\u5897\u52a0\u3059\u308b\u72b6\u6cc1\u3067\u306fHDL\u306e\u6a5f\u80fd\u4f4e\u4e0b\u304c\u8d77\u304d\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001HDL\u306e\u4e2d\u3067\u2f9b\u30e9\u30f3\u30ca\u30fc\u3068\u30ec\u30b9\u30ea\u30f3\u30b0\u306eapoA-I\u767a\u73fe\u30ec\u30d9\u30eb\u304c\u6700\u3082\u2fbc\u304f\u3001apoA-II\u767a\u73fe\u30ec\u30d9\u30eb\u304c\u6700\u3082\u4f4e\u304b\u3063\u305f\u3053\u3068\u3092\u2f70\u3057\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30e9\u30f3\u30ca\u30fc\u3068\u30ec\u30b9\u30ea\u30f3\u30b0\u3067\u306f\u3088\u308a\u2f24\u304d\u306aHDL\uff08HDL2\uff09\u3092\u6301\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u30ec\u30b9\u30ea\u30f3\u30b0\u306746nm\u3001\u30e9\u30f3\u30ca\u30fc\u306745nm\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u91cd\u91cf\u6319\u3052\u306f\u6700\u3082\u5c0f\u3055\u304f33nm\u3067\u3057\u305f\u3002\u305f\u3060\u3057\u3001\u5bfe\u7167\u7fa4\u3067\u306f28nm\u3088\u308a\u306f\u5927\u304d\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6050\u3089\u304f\u30ec\u30b9\u30ea\u30f3\u30b0\u306f\u529b\u3060\u3051\u3067\u306a\u304f\u3001\u6301\u4e45\u529b\u3082\u975e\u5e38\u306b\u5fc5\u8981\u306a\u7af6\u6280\u306a\u306e\u3067\u3057\u3087\u3046\u3002\u30d1\u30ef\u30fc\u3084\u77ac\u767a\u529b\u306e\u30cf\u30f3\u30de\u30fc\u6295\u3052\u3084\u91cd\u91cf\u6319\u3052\u3067\u306f\u6301\u4e45\u529b\u3001\u6709\u9178\u7d20\u904b\u52d5\u306f\u91cd\u8981\u8996\u3055\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u6709\u9178\u7d20\u904b\u52d5\u306f\u30b9\u30dd\u30fc\u30c4\u306e\u7a2e\u985e\u3084BMI\u306b\u95a2\u4fc2\u306a\u304f\u3001HDL\u7c92\u2f26\u30b5\u30a4\u30ba\u3001apoA-I\u6fc3\u5ea6\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3001\u6297\u9178\u5316\u6d3b\u6027\u304c\u5897\u52a0\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u2f70\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4e00\u822c\u7684\u306b\u306fHDL\u306e\u5927\u304d\u3055\u306f\u5927\u304d\u3044\u65b9\u304c\u826f\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u79c1\u306f\u3053\u308c\u3082\u8cea\u306e\u554f\u984c\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001apoA-II\u304c\u3042\u3063\u3066\u5927\u304d\u3044HDL\u306f\u8cea\u304c\u60aa\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>apoA-II\u304c\u591a\u3044\u3068PON-1\u3068\u6297\u9178\u5316\u6d3b\u6027\u306e\u4f4e\u4e0b\u304c\u8d77\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u30cf\u30f3\u30de\u30fc\u6295\u3052\u3084\u91cd\u91cf\u6319\u3052\u306a\u3069\u306e\u904b\u52d5\u306e\u8cea\u306fHDL\u306e\u8cea\u3092\u4e0b\u3052\u3066\u3044\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n<p>\u7b4b\u30c8\u30ec\uff0b\u7cd6\u8cea\u6442\u53d6\u3060\u3068\u3044\u304f\u3089HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u304f\u3066\u3082\u8981\u6ce8\u610f\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u5065\u5eb7\u306e\u305f\u3081\u306b\u306f\u904b\u52d5\u304c\u5fc5\u8981\u3067\u3059\u3002\u30a2\u30b9\u30ea\u30fc\u30c8\u3067\u306f\u306a\u304f\u3001\u5065\u5eb7\u306e\u305f\u3081\u306b\u904b\u52d5\u3059\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u6709\u9178\u7d20\u904b\u52d5\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cEnhanced functional and structural properties of high-density lipoproteins from runners and wrestlers compared to throwers and lifters\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u6295\u64f2\u3084\u91cd\u91cf\u6319\u3052\u3068\u6bd4\u8f03\u3057\u305f\u30e9\u30f3\u30ca\u30fc\u3084\u30ec\u30b9\u30ea\u30f3\u30b0\u9078\u624b\u306eHDL\u306e\u6a5f\u80fd\u7684\u304a\u3088\u3073\u69cb\u9020\u7684\u7279\u6027\u304c\u5411\u4e0a\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19788863\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u904b\u52d5\u306e\u8cea\u3068HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u300d\u3067\u306f\u3001\u6709\u9178\u7d20\u904b\u52d5\u304cHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5897\u52a0\u306b\u306f\u6700\u3082\u9069\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002 \u3067\u306f\u3001\u904b\u52d5\u306e\u8cea\u306b\u3088\u308aHDL\u306e\u8cea\u306b\u9055\u3044\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f 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