{"id":24991,"date":"2024-02-09T08:49:11","date_gmt":"2024-02-08T23:49:11","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=24991"},"modified":"2024-02-09T08:49:11","modified_gmt":"2024-02-08T23:49:11","slug":"%e7%b3%96%e8%b3%aa%e5%88%b6%e9%99%90%e3%81%a7sdldl%e3%81%8c%e6%b8%9b%e5%b0%91%e3%81%99%e3%82%8b","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=24991","title":{"rendered":"\u7cd6\u8cea\u5236\u9650\u3067sdLDL\u304c\u6e1b\u5c11\u3059\u308b"},"content":{"rendered":"

LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u6570\u5024\u3092\u6c17\u306b\u3057\u3066\u3082\u4ed5\u65b9\u304c\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u6570\u5024\u3088\u308a\u3082\u8cea\u3092\u6c17\u306b\u3057\u305f\u65b9\u304c\u826f\u3044\u3068\u601d\u3044\u307e\u3059\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u30ea\u30dd\u30bf\u30f3\u30d1\u30afLDL\u306f\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\uff08sdLDL\uff09\u3068\u5927\u304d\u306a\u5065\u5eb7\u7684\u306aLDL\u304c\u3042\u308a\u307e\u3059\u3002\u3082\u3061\u308d\u30932\u3064\u306b\u5b8c\u5168\u306b\u5206\u304b\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u9023\u7d9a\u7684\u3001\u6bb5\u968e\u7684\u306b\u5927\u304d\u3055\u304c\u5909\u5316\u3057\u307e\u3059\u3002<\/p>\n

\u3067\u306f\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u30682\u578b\u7cd6\u5c3f\u75c5\u306e\u4eba\u3067\u306fLDL\u306f\u3069\u3046\u306a\u308b\u3067\u3057\u3087\u3046\u3002\u5bfe\u8c61\u306fBMI25\u4ee5\u4e0a\u306e\u7cd6\u5c3f\u75c5\u306e\u4eba\u3067\u30012\u5e74\u9593\u7cd6\u8cea\u5236\u9650\u3092\u3057\u305f194\u4eba\u3068\u6a19\u6e96\u6cbb\u7642\u3092\u884c\u3063\u305f68\u4eba\u304c\u5bfe\u8c61\u3067\u3059\u3002\u7cd6\u8cea\u5236\u9650\u306e50%\u3068 \u6a19\u6e96\u6cbb\u7642\u306e59%\u304c\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u307e\u3057\u305f \u3002<\/p>\n

\u6a19\u6e96\u6cbb\u7642\u7fa4\u3067\u306f\u3001\u8102\u8cea\u3001\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u3001\u30a2\u30dd\u30bf\u30f3\u30d1\u30af\u3001\u8840\u5727\u3001CIMT\uff08\u9838\u52d5\u8108\u5185\u819c\u4e2d\u819c\u539a\uff09\u3001\u8102\u8cea\u4f4e\u4e0b\u85ac\u304a\u3088\u3073\u964d\u5727\u85ac\u306e\u7d4c\u6642\u7684\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u7cd6\u8cea\u5236\u9650\u7fa4\u3067\u306f\u30011\u5e74\u5f8c\u304a\u3088\u30732\u5e74\u5f8c\u306e\u5e73\u5747LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u5897\u52a0\u3057\u3001\u4e2d\u6027\u8102\u80aa\u3068\u8840\u5727\u306f\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u7cd6\u8cea\u5236\u9650\u3067\u30b9\u30bf\u30c1\u30f3\u306e\u4f7f\u7528\u91cf\u306f2\u5e74\u76ee\u3067\u3082\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u4ed6\u306e\u8102\u8cea\u4f4e\u4e0b\u85ac\u306e\u4f7f\u7528\u91cf\u306f2\u5e74\u524d\u304b\u3089\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306fLDL\u8868\u73fe\u578b\uff08Phenotype\uff09\u30d1\u30bf\u30fc\u30f3\u3068LDL\u306e\u30d4\u30fc\u30af\u76f4\u5f84 (\u00c5) \u306e\u5206\u5e03\u3067\u3059\u3002\u30d1\u30bf\u30fc\u30f3A\u306f\u5927\u304d\u306a\u6d6e\u904a\u6027\u306e\u8cea\u306e\u826f\u3044LDL\u7c92\u5b50\u304b\u3089\u306a\u308bLDL\u3067\u3042\u308a\u3001\u30d1\u30bf\u30fc\u30f3B\u306f\u5c0f\u3055\u306a\u3001\u9ad8\u5bc6\u5ea6\u306e\u60aa\u3044LDL\u7c92\u5b50\u304b\u3089\u306a\u308bLDL\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u300c\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607<\/a>\u300d\u306a\u3069\u53c2\u7167\uff09\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u30d1\u30bf\u30fc\u30f3A (LDL\u30d4\u30fc\u30af\u76f4\u5f84 > 21.88 nm \u306e\u5927\u304d\u306aLDL\u7c92\u5b50\u306e\u512a\u52e2)\u3001\u30d1\u30bf\u30fc\u30f3B (LDL\u30d4\u30fc\u30af\u76f4\u5f84 < 21.55 nm \u306e\u5c0f\u3055\u306aLDL\u7c92\u5b50\u306e\u512a\u52e2)\u3001\u307e\u305f\u306f\u305d\u306e\u4e2d\u9593\u30d1\u30bf\u30fc\u30f3 I (LDL \u30d4\u30fc\u30af\u76f4\u5f84\u306f 21.55 \uff5e 21.88 nm)\u3067\u5206\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e0a\u306e\u56f3a\u306f\u7cd6\u8cea\u5236\u9650\u3001b\u306f\u6a19\u6e96\u6cbb\u7642\u3067\u3001\u4e0a\u304b\u3089\u9806\u306b\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30011\u5e74\u5f8c\u30012\u5e74\u5f8c\u3067\u3059\u3002<\/p>\n

\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u306f\u7cd6\u8cea\u5236\u9650\u7fa4\u306e48.7\uff05\u304c\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\u512a\u52e2\u306e\u30d1\u30bf\u30fc\u30f3B\u3067\u3001\u30d1\u30bf\u30fc\u30f3A\u306f35.3\uff05\u3060\u3051\u3067\u3057\u305f\u30021\u5e74\u5f8c\u306b\u306f\u30d1\u30bf\u30fc\u30f3A\u306f\u5927\u5e45\u306b\u5897\u52a0\u3057\u300163.3\uff05\u30012\u5e74\u5f8c\u3067\u308260.7\uff05\u3067\u3057\u305f\u30022\u5e74\u5f8c\u3067\u30d1\u30bf\u30fc\u30f3A\u304c\u5c11\u3057\u6e1b\u5c11\u3059\u308b\u306e\u306f\u3001\u3084\u306f\u308a\u6bb5\u3005\u3068\u7cd6\u8cea\u5236\u9650\u304c\u7518\u304f\u306a\u3063\u3066\u304f\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u4e00\u65b9\u6a19\u6e96\u6cbb\u7642\u7fa4\u3067\u306f\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306757.1\uff05\u304c\u30d1\u30bf\u30fc\u30f3B\u3067\u3001\u30d1\u30bf\u30fc\u30f3A\u306f57.1\uff05\u3067\u3057\u305f\u30021\u5e74\u5f8c\u30d1\u30bf\u30fc\u30f3A\u306f\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u300125.9\uff05\u30012\u5e74\u5f8c\u3067\u308229.2\uff05\u3067\u3057\u305f\u3002\u9006\u306b\u30d1\u30bf\u30fc\u30f3B\u306f1\u5e74\u5f8c\u5927\u5e45\u306b\u5897\u52a0\u3057\u300160.3\uff05\u3068\u306a\u308a\u30012\u5e74\u5f8c\u3067\u308245.8\uff05\u3067\u3057\u305f\u3002<\/p>\n

sdLDL\u304c\u591a\u304f\u306a\u308b\u3068\u3001\u69d8\u3005\u306a\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\uff08\u300c\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\uff08sdLDL\uff09\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u51a0\u52d5\u8108\u5fc3\u81d3\u75c5\u306e\u30ea\u30b9\u30af<\/a>\u300d\u306a\u3069\u53c2\u7167\uff09\u305d\u3057\u3066\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3001\u7279\u306b\u679c\u7cd6\u306e\u6442\u53d6\u306fsdLDL\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\uff08\u300c\u679c\u7cd6\u306f\u4e2d\u6027\u8102\u80aa\u3092\u5897\u52a0\u3055\u305b\u3001\u5c0f\u3055\u306aLDL\u3084\u9178\u5316LDL\u3082\u5897\u52a0\u3055\u305b\u308b<\/a>\u300d\u306a\u3069\u53c2\u7167\uff09\u3055\u3089\u306b\u3001\u4f4e\u8102\u80aa\u98df\u3082sdLDL\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\uff08\u300c\u4f4e\u8102\u80aa\u98df\u306f\u5c0f\u3055\u306a\u5371\u967a\u306aLDL\uff08sdLDL\uff09\u3092\u5897\u52a0\u3055\u305b\u308b<\/a>\u300d\u53c2\u7167\uff09<\/p>\n

\u3064\u307e\u308a\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308c\u3070\u3001sdLDL\u306e\u5897\u52a0\u306f\u9632\u3050\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3059\u3002\u6a19\u6e96\u6cbb\u7642\u3092\u3057\u3066\u3044\u308b\u3068\u4eca\u56de\u306e\u7814\u7a76\u306e\u3088\u3046\u306bsdLDL\u304c\u5897\u52a0\u3057\u3066\u304f\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607\u3092\u8d77\u3053\u3059\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u5927\u304d\u306a\u826f\u8cea\u306aLDL\u306e\u5897\u52a0\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5897\u52a0\u3092\u8d77\u3053\u3059\u306e\u306f\u4e0d\u601d\u8b70\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f2\u5e74\u5f8c\u3001\u7cd6\u8cea\u5236\u9650\u306b\u3088\u308a\u5c0f\u3055\u306aLDL\u304c 23% \u6e1b\u5c11\u3057\u3001\u5927\u304d\u306aLDL\u304c 29%\u5897\u52a0\u3057\u307e\u3057\u305f\u304c\u3001\u7dcfLDL\u7c92\u5b50\u6fc3\u5ea6\u3084ApoB\u306b\u306f\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3082\u3061\u308d\u3093CIMT\uff08\u9838\u52d5\u8108\u5185\u819c\u4e2d\u819c\u539a\uff09\u3082\u5897\u52a0\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5897\u52a0\u3057\u3066\u3082\u3001\u6c17\u306b\u3059\u308b\u5fc5\u8981\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u6a19\u6e96\u6cbb\u7642\u3060\u3051\u3092\u884c\u3063\u3066\u3044\u308b\u65b9\u304c\u6050\u308d\u3057\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u300cImpact of a 2-year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes\u300d<\/span><\/p>\n

\u300c2 \u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u6307\u6a19\u306b\u5bfe\u3059\u308b\u6804\u990a\u30b1\u30c8\u30fc\u30b7\u30b9\u306e 2 \u5e74\u9593\u306e\u8a66\u9a13\u306e\u5f71\u97ff\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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