\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607<\/a>\u300d\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u8a08\u7b97\u5f0f\u3067\u6c42\u3081\u308b\u306e\u3067\u3001\u7cd6\u8cea\u5236\u9650\u6642\u306b\u306f\u975e\u5e38\u306b\u6b63\u78ba\u6027\u306b\u7591\u554f\u304c\u3042\u308b\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002<\/p>\n\u3057\u304b\u3057\u3001\u306a\u3093\u3068\u306a\u304f\u308f\u304b\u3063\u305f\u3088\u3046\u3067\u308f\u304b\u3089\u306a\u3044\u90e8\u5206\u3082\u3042\u308a\u307e\u3059\u3002\u306a\u306e\u3067\u3001\u305d\u308c\u4ee5\u5916\u306b\u3082\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8003\u3048\u3066\u307f\u307e\u3057\u305f\u3002<\/p>\n
\u307e\u305a\u3001LDL\u306fVLDL\u304b\u3089\u4f5c\u3089\u308c\u307e\u3059\u3002VLDL\u306f\u809d\u81d3\u3067\u4f5c\u3089\u308c\u3001\u4e2d\u6027\u8102\u80aa\u3092\u305f\u304f\u3055\u3093\u542b\u307f\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u540c\u6642\u306b\u542b\u3093\u3060\u3082\u306e\u3067\u3059\u3002\u305d\u3057\u3066\u3001VLDL\u306f\u69d8\u3005\u306a\u7d44\u7e54\u306b\u30a8\u30cd\u30eb\u30ae\u30fc\u3067\u3042\u308b\u8102\u80aa\u9178\u3092\u4e2d\u6027\u8102\u80aa\u306e\u5f62\u3067\u914d\u308a\u306b\u884c\u304d\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u4e2d\u6027\u8102\u80aa\u3092\u914d\u308b\u3068\u8377\u7269\u304c\u6e1b\u3063\u3066\u3001\u5c0f\u3055\u304f\u306a\u308a\u3001LDL\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n
\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u3001\u9ad8\u8840\u7cd6\u306b\u306a\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u305f\u304f\u3055\u3093\u5206\u6ccc\u3055\u308c\u3001\u7d44\u7e54\u3067\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306f\u30d6\u30c9\u30a6\u7cd6\u3067\u3042\u308b\u6642\u9593\u304c\u591a\u304f\u306a\u308a\u307e\u3059\u3002\u7b4b\u8089\u3084\u809d\u81d3\u3067\u306f\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u3068\u3057\u3066\u30d6\u30c9\u30a6\u7cd6\u3092\u3044\u304f\u3089\u304b\u8caf\u3081\u3053\u3080\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u306e\u3088\u3046\u306a\u5834\u5408\u3001\u3042\u3093\u307e\u308a\u9811\u5f35\u3063\u3066\u4e2d\u6027\u8102\u80aa\u3092\u5c4a\u3051\u308b\u5fc5\u8981\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3046\u3059\u308b\u3068\u3001VLDL\u306e\u4e2d\u6027\u8102\u80aa\u3068LDL\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30a8\u30b9\u30c6\u30eb\u3092\u4ea4\u63db\u3057\u3066\u3001LDL\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5c11\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n
\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u3042\u308b\u3068\u3001\u3055\u3089\u306b\u809d\u81d3\u3067\u306e\u4e2d\u6027\u8102\u80aa\u306e\u5408\u6210\u306f\u4fc3\u9032\u3055\u308c\u3001VLDL\u306e\u4e2d\u306b\u542b\u307e\u308c\u308b\u4e2d\u6027\u8102\u80aa\u304c\u591a\u304f\u306a\u308a\u3001VLDL1\u3068\u3044\u3046\u5927\u304d\u306aVLDL\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002\u3053\u306eVLDL1\u306b\u306f\u30a2\u30dd\u30bf\u30f3\u30d1\u30af\u306eApoC-3\u304c\u5897\u52a0\u3059\u308b\u3088\u3046\u3067\u3001\u3053\u306eApoC-3\u304c\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30ea\u30d1\u30fc\u30bc\u304a\u3088\u3073\u809d\u81d3\u30ea\u30d1\u30fc\u30bc\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001VLDL1\u304c\u7d44\u7e54\u306b\u4e2d\u6027\u8102\u80aa\u3092\u5c4a\u3051\u3089\u308c\u305a\u3001\u8840\u4e2d\u306b\u9577\u304f\u5b58\u5728\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u7d50\u679c\u7684\u306b\u8840\u4e2d\u306e\u4e2d\u6027\u8102\u80aa\u5024\u304c\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n
\u307e\u305f\u3001VLDL1\u304c\u9577\u304f\u3068\u3069\u307e\u3063\u3066\u3044\u308b\u9593\u306b\u3001LDL\u3084HDL\u306b\u4e2d\u6027\u8102\u80aa\u3092\u6e21\u3057\u3066\u3001\u4ee3\u308f\u308a\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30a8\u30b9\u30c6\u30eb\u3092\u3082\u3089\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081LDL\u3082HDL\u4e2d\u6027\u8102\u80aa\u304c\u8c4a\u5bcc\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u306e\u4e2d\u6027\u8102\u80aa\u306f\u809d\u81d3\u30ea\u30d1\u30fc\u30bc\u306a\u3069\u306e\u4f5c\u7528\u3067\u7d44\u7e54\u306b\u6e21\u3055\u308c\u3001LDL\u3082HDL\u3082\u5c0f\u3055\u304f\u306a\u308a\u307e\u3059\u3002LDL\u306f\u5c0f\u3055\u304f\u306a\u308a\u771f\u306e\u60aa\u7389\u306e\u5c0f\u7c92\u5b50LDL\uff08sdLDL\uff09\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002HDL\u3082\u5c0f\u3055\u304f\u306a\u308a\u3001ApoA-1\u304c\u5916\u308c\u3066\u3057\u307e\u3044\u3001HDL\u3067\u306f\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u305d\u306e\u3088\u3046\u306b\u3057\u3066HDL\u304c\u4f4e\u5024\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n
<\/p>\n
\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u308b\u5834\u5408\u306b\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3082\u591a\u304f\u306a\u304f\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3082\u5c11\u306a\u3044\u3067\u3059\u3057\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u3057\u3066\u8102\u80aa\u3092\u30e1\u30a4\u30f3\u3067\u4f7f\u3044\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u7d44\u7e54\u3067\u306e\u8102\u80aa\u9178\u306e\u9700\u8981\u304c\u975e\u5e38\u306b\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u809d\u81d3\u3067\u306e\u4e2d\u6027\u8102\u80aa\u306e\u5408\u6210\u306f\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n
\u4e2d\u6027\u8102\u80aa\u306e\u5408\u6210\u306f\u5c11\u306a\u3044\u3051\u3069\u3001\u7d44\u7e54\u3067\u306e\u9700\u8981\u306f\u9ad8\u3044\u305f\u3081\u3001\u5c0f\u3055\u306aVLDL2\u3092\u305f\u304f\u3055\u3093\u4f5c\u308b\u5fc5\u8981\u304c\u51fa\u3066\u304d\u307e\u3059\u3002\u305d\u308c\u3092\u3069\u3093\u3069\u3093\u9001\u308a\u8fbc\u3093\u3067\u3001\u4e2d\u6027\u8102\u80aa\u3092\u5c4a\u3051\u308b\u306e\u3067\u3059\u304c\u3001\u305d\u3046\u3059\u308b\u3068LDL\u3082\u305f\u304f\u3055\u3093\u3067\u304d\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3063\u304b\u308a\u3057\u3066\u3001\u3055\u3089\u306b\u7d44\u7e54\u3067\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u3057\u3066\u306e\u8102\u80aa\u306e\u9700\u8981\u304c\u9ad8\u304f\u306a\u308c\u3070\u306a\u308b\u307b\u3069LDL\u304c\u5897\u3048\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002\u3057\u304b\u3057\u3001VLDL2\u304b\u3089\u3067\u304d\u308bLDL\u306f\u901a\u5e38\u5927\u304d\u306a\u7c92\u5b50\u306eLDL\u3067\u3059\u3002\u305d\u306e\u3088\u3046\u306b\u3057\u3066LDL\u304c\u5897\u52a0\u3057\u3066\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n
\u3067\u306f\u3001\u7cd6\u8cea\u5236\u9650\u306e\u6642\u306b\u3069\u3046\u3059\u308c\u3070LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u4e0b\u304c\u308b\u304b\u3068\u3044\u3046\u3068\u3001\u4e8c\u3064\u65b9\u6cd5\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u4e00\u3064\u76ee\u306f\u90aa\u9053\u3067\u3059\u304c\u3001\u5c11\u3057\u3060\u3051\u7cd6\u8cea\u306e\u6442\u53d6\u91cf\u3092\u5897\u3084\u3059\u3053\u3068\u3067\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u7d44\u7e54\u306b\u5c11\u3057\u30d6\u30c9\u30a6\u7cd6\u304c\u53d6\u308a\u8fbc\u307e\u308c\u3001\u7d44\u7e54\u3067\u306e\u4e2d\u6027\u8102\u80aa\u306e\u9700\u8981\u304c\u6e1b\u308b\u306e\u3067\u3001VLDL\u304c\u5c11\u306a\u304f\u306a\u308a\u3001LDL\u3082\u6e1b\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3082\u3046\u4e00\u3064\u306e\u65b9\u6cd5\u306f\u3001\u8102\u80aa\u3092\u3082\u3063\u3068\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u8102\u80aa\u306f\u5438\u53ce\u3055\u308c\u308b\u3068\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306b\u3088\u3063\u3066\u7d44\u7e54\u306b\u904b\u3070\u308c\u307e\u3059\u3002\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306fVLDL\u3068\u540c\u3058\u3088\u3046\u306b\u7d44\u7e54\u306b\u4e2d\u6027\u8102\u80aa\u3092\u5c4a\u3051\u308b\u306e\u304c\u4ed5\u4e8b\u3067\u3059\u3002\u98df\u4e8b\u3067\u6442\u3063\u305f\u8102\u80aa\u306f\u3059\u3050\u306b\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u3067\u904b\u3070\u308c\u307e\u3059\u306e\u3067\u3001\u305d\u306e\u4e2d\u6027\u8102\u80aa\u306e\u91cf\u3092\u5897\u3084\u305b\u3070\u3001\u304a\u306e\u305a\u3068VLDL\u306e\u8ca0\u62c5\u304c\u8efd\u6e1b\u3055\u308c\u307e\u3059\u3002\u305d\u3046\u3059\u308c\u3070LDL\u306f\u5c11\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n
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