{"id":26875,"date":"2025-06-04T08:54:19","date_gmt":"2025-06-03T23:54:19","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=26875"},"modified":"2025-06-04T08:54:19","modified_gmt":"2025-06-03T23:54:19","slug":"%e3%83%97%e3%83%ad%e3%83%88%e3%83%b3%e3%83%9d%e3%83%b3%e3%83%97%e9%98%bb%e5%ae%b3%e8%96%ac%ef%bc%88ppi%ef%bc%89%e3%81%ae%e4%b8%8d%e9%81%a9%e5%88%87%e3%81%aa%e4%bd%bf%e7%94%a8%e3%81%af%e5%86%a0","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=26875","title":{"rendered":"\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff08PPI\uff09\u306e\u4e0d\u9069\u5207\u306a\u4f7f\u7528\u306f\u51a0\u52d5\u8108\u75be\u60a3\u60a3\u8005\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u5897\u52a0\u3055\u305b\u308b"},"content":{"rendered":"

\u5faa\u74b0\u5668\u79d1\u3067\u3042\u308d\u3046\u3068\u4ed6\u306e\u79d1\u3067\u3042\u308d\u3046\u3068\u3001\u533b\u5e2b\u306f\u6297\u8840\u5c0f\u677f\u7642\u6cd5\u3092\u53d7\u3051\u3066\u3044\u308b\u51a0\u52d5\u8108\u75be\u60a3\u60a3\u8005\u306e\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u8b66\u6212\u3057\u3066\u3044\u308b\u3067\u3057\u3087\u3046\u3002 \u3057\u304b\u3057\u3001\u591a\u304f\u306e\u533b\u5e2b\u306f\u4e0b\u90e8\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u3092\u7121\u8996\u3057\u3066\u4e0a\u90e8\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u4e88\u9632\u306b\u91cd\u70b9\u3092\u7f6e\u3044\u3066\u3044\u307e\u3059\u3002 \u5b9f\u969b\u3001\u6297\u8840\u5c0f\u677f\u85ac\u306f\u4e0b\u90e8\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u767a\u751f\u7387\u3092\u5897\u52a0\u3055\u305b\u3001PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u306e\u4f7f\u7528\u306b\u3088\u308a\u60aa\u5316\u3057\u307e\u3059\u3002\uff08\u300cNSAIDs\u3068PPI\u4f75\u7528\u3067\u4e0b\u90e8\u6d88\u5316\u7ba1\u51fa\u8840\u30ea\u30b9\u30af\u4e0a\u6607<\/a>\u300d\u53c2\u7167\uff09\u3055\u3089\u306b\u3001PPI\u304c\u6297\u8840\u5c0f\u677f\u85ac\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3001\u6297\u8840\u5c0f\u677f\u85ac\u306e\u52b9\u679c\u3092\u5f31\u3081\u308b\u3053\u3068\u304c\u591a\u304f\u306e\u7814\u7a76\u3067\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3042\u308b\u7814\u7a76\u3067\u306f\u3001PPI\u3068\u6297\u8840\u5c0f\u677f\u85ac\u306e\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u4f75\u7528\u306f\u3001\u7d4c\u76ae\u7684\u51a0\u52d5\u8108\u30a4\u30f3\u30bf\u30fc\u30d9\u30f3\u30b7\u30e7\u30f3\uff08PCI\uff09\u5f8c\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u30ea\u30b9\u30af\u3092\u691c\u8a0e\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u8868\u306f\u3053\u3053\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n

\u5bfe\u8c61\u306fPCI\u5f8c2\u9031\u9593\u4ee5\u5185\u306b\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u51e6\u65b9\u3092\u53d7\u3051\u305f99,836\u4eba\u3067\u3001\u3053\u306e\u3046\u3061\u300135,772\u4eba\uff0835.8%\uff09\u306fPPI\u3092\u4f75\u7528\u3057\u300164,064\u4eba\uff0864.2%\uff09\u306fPPI\u3092\u4f75\u7528\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4e0b\u306e\u8868\u306f\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u5358\u72ec\u7fa4\u3068PPI\u4f75\u7528\u7fa4\u306e\u69d8\u3005\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\nHR\uff0895\uff05CI\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u5fc3\u7b4b\u6897\u585e<\/td>\n<\/tr>\n
\u00a0\u00a0\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.00<\/td>\n<\/tr>\n
\u00a0\u00a0PPI + \u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.23 (1.15\u20131.32)<\/td>\n<\/tr>\n
\u51a0\u52d5\u8108\u75be\u60a3<\/td>\n<\/tr>\n
\u00a0\u00a0\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.00<\/td>\n<\/tr>\n
\u00a0\u00a0PPI + \u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.28 (1.24\u20131.33)<\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\n<\/tr>\n
\u00a0\u00a0\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.00<\/td>\n<\/tr>\n
\u00a0\u00a0PPI + \u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.21 (1.05\u20131.40)<\/td>\n<\/tr>\n
\u5168\u6b7b\u4ea1\u7387<\/td>\n<\/tr>\n
\u00a0\u00a0\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.00<\/td>\n<\/tr>\n
\u00a0\u00a0PPI + \u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.71 (1.58\u20131.86)<\/td>\n<\/tr>\n
\u51a0\u52d5\u8108\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u7387<\/td>\n<\/tr>\n
\u00a0\u00a0\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.00<\/td>\n<\/tr>\n
\u00a0\u00a0PPI + \u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb<\/td>\n1.52 (1.37\u20131.69)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u5358\u72ec\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306bPPI\u4f75\u7528\u7fa4\u3067\u306f\u3001\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u304c1.23\u500d\u3001\u51a0\u52d5\u8108\u75be\u60a31.28\u500d\u3001\u8133\u5352\u4e2d1.21\u500d\u3001\u5168\u539f\u56e0\u6b7b\u4ea1\u73871.71\u500d\u3001\u51a0\u52d5\u8108\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u304c1.52\u500d\u3067\u3057\u305f\u3002<\/p>\n

\u4ed6\u306e\u7814\u7a76\u3082\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u8868\u3082\u3053\u3053\u3088\u308a\u6539\u5909\uff09\u6025\u6027\u5fc3\u7b4b\u6897\u585e\u5f8c\u306b\u6297\u8840\u5c0f\u677f\u85ac2\u5264\u4f75\u7528\u7642\u6cd5\uff08DAPT\uff09\u3092\u53d7\u3051\u3066\u3044\u308b17,274\u4eba\u304c\u5bfe\u8c61\u3067\u3059\u300266.6%\uff08 11,487\u4eba\uff09\u304cPPI\u306b\u3088\u308b\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n\n\n\n\n\n\n
\u81e8\u5e8a\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/strong><\/th>\nPPI\u3042\u308a\uff08\uff05\uff09<\/strong><\/th>\nPPI\u306a\u3057\uff08\uff05\uff09<\/strong><\/th>\n\u8abf\u6574OR\uff0895\uff05CI\uff09<\/strong><\/th>\n<\/tr>\n<\/thead>\n
\u6d88\u5316\u7ba1\u51fa\u8840<\/td>\n122\uff081.1\uff05\uff09<\/td>\n10\uff080.2\uff05\uff09<\/td>\n5.574 (2.902-10.697)<\/span><\/td>\n<\/tr>\n
\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u304a\u3088\u3073\u8133\u8840\u7ba1\u306e\u6709\u5bb3\u4e8b\u8c61<\/td>\n568 (5.0%)<\/td>\n271\uff084.7\uff05\uff09<\/td>\n1.026 (0.877-1.203)<\/td>\n<\/tr>\n
\u5168\u539f\u56e0\u6b7b\u4ea1<\/td>\n471\uff084.1\uff05\uff09<\/td>\n248 (4.3%)<\/td>\n0.938 (0.791-1.112)<\/td>\n<\/tr>\n
\u5fc3\u7b4b\u6897\u585e<\/td>\n61\uff080.5\uff05\uff09<\/td>\n16\uff080.3\uff05\uff09<\/td>\n1.529 (0.872-2.678)<\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\n69\uff080.6\uff05\uff09<\/td>\n16\uff080.3\uff05\uff09<\/td>\n2.125 (1.216-3.682)<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u4e0a\u306e\u8868\u306b\u793a\u3059\u3088\u3046\u306b\u3001\u6d88\u5316\u7ba1\u51fa\u8840\u306f\u306a\u3093\u3068PPI\u3042\u308a\u306e\u65b9\u304c\u591a\u304f\u3001\u30ea\u30b9\u30af\u304c5.574\u500d\u306b\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u8133\u5352\u4e2d\u306fPPI\u3042\u308a\u306e\u65b9\u304c2.125\u500d\u3067\u3057\u305f\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n
\u81e8\u5e8a\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/strong><\/th>\n30\u65e5\u9593<\/strong><\/th>\n6\u30f6\u6708<\/strong><\/th>\n1\u5e74<\/strong><\/th>\n2\u5e74<\/strong><\/th>\n<\/tr>\n
<\/th>\n\u8abf\u6574HR\uff0895\uff05CI\uff09<\/strong><\/th>\n\u8abf\u6574HR\uff0895\uff05CI\uff09<\/strong><\/th>\n\u8abf\u6574HR\uff0895\uff05CI\uff09<\/strong><\/th>\n\u8abf\u6574HR\uff0895\uff05CI\uff09<\/strong><\/th>\n<\/tr>\n<\/thead>\n
\u6d88\u5316\u7ba1\u51fa\u8840<\/td>\n5.577 (2.903-10.696)<\/span><\/td>\n4.988 (2.742-9.069)<\/span><\/td>\n4.331 (2.488-7.563)<\/span><\/td>\n3.650 (2.188-6.082)<\/span><\/td>\n<\/tr>\n
\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u304a\u3088\u3073\u8133\u8840\u7ba1\u306e\u6709\u5bb3\u4e8b\u8c61<\/td>\n1.049 (0.905-1.211)<\/td>\n1.070 (0.934-1.225)<\/td>\n1.095 (0.963-1.246)<\/td>\n1.123 (0.994-1.270)<\/td>\n<\/tr>\n
\u5168\u539f\u56e0\u6b7b\u4ea1<\/td>\n0.965 (0.822-1.131)<\/td>\n0.945 (0.817-1.096)<\/td>\n0.940 (0.817-1.083)<\/td>\n0.971 (0.848-1.112)<\/td>\n<\/tr>\n
\u5fc3\u7b4b\u6897\u585e<\/td>\n1.297 (0.855-1.968)<\/td>\n1.580 (1.102-2.265)<\/strong><\/span><\/td>\n1.812 (1.296-2.536)<\/strong><\/span><\/td>\n1.773 (1.301-2.412)<\/strong><\/span><\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\n2.202 (1.287-3.763)<\/strong><\/span><\/td>\n2.270 (1.401-3.675)<\/strong><\/span><\/td>\n2.261 (1.454-3.515)<\/strong><\/span><\/td>\n2.072 (1.388-3.091)<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u3001PPI\u306e\u4f7f\u7528\u671f\u9593\u3067\u5206\u3051\u308b\u3068\u6d88\u5316\u7ba1\u51fa\u8840\u3068\u8133\u5352\u4e2d\u306b\u95a2\u3057\u3066\u306f30\u65e5\u9593\u304b\u30892\u5e74\u9593\u307e\u3067\u305a\u3063\u3068\u30ea\u30b9\u30af\u5897\u52a0\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u5fc3\u7b4b\u6897\u585e\u306f6\u304b\u6708\u4ee5\u4e0a\u306ePPI\u4f7f\u7528\u3067\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u3082\u3046\u4e00\u3064\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u56f3\u3082\u3053\u3053\u3088\u308a\uff09\u7d4c\u76ae\u7684\u51a0\u52d5\u8108\u30a4\u30f3\u30bf\u30fc\u30d9\u30f3\u30b7\u30e7\u30f3 (PCI) \u5f8c\u306e15,839\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u30c1\u30ab\u30b0\u30ec\u30ed\u30eb\u3068\u3044\u3046\u85ac\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u3092\u6bd4\u8f03\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u4eca\u56de\u306f\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u307f\u3092\u63a1\u308a\u4e0a\u3052\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u53f3\u5074\u306e\u65b9\u304c\u30a2\u30b9\u30d4\u30ea\u30f3\u7fa4\u3067\u3001PPI\u3092\u4f75\u7528\u3057\u305f\u4eba\u3068\u4f75\u7528\u3057\u3066\u3044\u306a\u3044\u4eba\u3067\u6bd4\u8f03\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u4e0a\u304b\u3089\u3001\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\uff08POCE\uff1a\u5168\u6b7b\u4ea1\u7387\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u307e\u305f\u306f\u518d\u8840\u884c\u518d\u5efa\u8853\uff09\u3001\u30b9\u30c6\u30f3\u30c8\u8840\u6813\u75c7\u3001BARC\uff08Bleeding Academic Research Consortium\uff09\u306e\u30bf\u30a4\u30d73\u307e\u305f\u306f5\u306e\u51fa\u8840\u3001\u30bf\u30a4\u30d72\u306e\u51fa\u8840\u3001\u6709\u5bb3\u81e8\u5e8a\u30a4\u30d9\u30f3\u30c8\uff08NACE\uff09\u3067\u3059\u3002PPI\u306e\u4f75\u7528\u306b\u3088\u308a\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u306f1.27\u500d\u3001\u5168\u539f\u56e0\u6b7b\u4ea1\u306f1.53\u500d\u3001\u5fc3\u7b4b\u6897\u585e1.46\u500d\u3001\u8133\u5352\u4e2d1.92\u500d\u3001\u518d\u8840\u884c\u518d\u5efa\u88531.22\u500d\u3001\u6709\u5bb3\u81e8\u5e8a\u30a4\u30d9\u30f3\u30c81.26\u500d\u3067\u3057\u305f\u3002<\/p>\n

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