{"id":27618,"date":"2024-09-18T08:47:27","date_gmt":"2024-09-17T23:47:27","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=27618"},"modified":"2024-09-18T08:47:27","modified_gmt":"2024-09-17T23:47:27","slug":"%e6%80%a5%e6%80%a7%e5%bf%83%e7%ad%8b%e6%a2%97%e5%a1%9e%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e6%8a%97%e8%a1%80%e5%b0%8f%e6%9d%bf%e8%96%ac%ef%bc%92%e5%89%a4%e4%bd%b5%e7%94%a8%e7%99%82%e6%b3%95%e3%81%a8","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=27618","title":{"rendered":"\u6025\u6027\u5fc3\u7b4b\u6897\u585e\u306b\u304a\u3051\u308b\u6297\u8840\u5c0f\u677f\u85ac\uff12\u5264\u4f75\u7528\u7642\u6cd5\u3068\u4f75\u7528\u3057\u305fPPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u306e\u6709\u5bb3\u6027"},"content":{"rendered":"

\u5fc3\u81d3\u306e\u5c02\u9580\u533b\u3067\u3042\u308d\u3046\u3068\u4ed6\u306e\u79d1\u3067\u3042\u308d\u3046\u3068\u3001\u81e8\u5e8a\u533b\u306f\u6297\u8840\u5c0f\u677f\u7642\u6cd5\u3092\u53d7\u3051\u3066\u3044\u308b\u51a0\u52d5\u8108\u75be\u60a3\u60a3\u8005\u306e\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u975e\u5e38\u306b\u8b66\u6212\u3057\u3066\u3044\u307e\u3059\u3002 \u305d\u3053\u3067\u3001\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u305d\u3046\u3068\u3001PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u3092\u51e6\u65b9\u3059\u308b\u3053\u3068\u3082\u591a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u6297\u8840\u5c0f\u677f\u85ac\u306f\u3044\u308f\u3086\u308b\u300c\u8840\u6db2\u3092\u30b5\u30e9\u30b5\u30e9\u306b\u3059\u308b\u300d\u85ac\u3067\u3059\u3002\u305d\u306e\u8840\u6db2\u3092\u30b5\u30e9\u30b5\u30e9\u306b\u3059\u308b\u85ac\u306b\u3001\u305d\u306e\u526f\u4f5c\u7528\u306e\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u305d\u3046\u3068\u3059\u308bPPI\u3092\u4f75\u7528\u3059\u308b\u3068\u3069\u3046\u306a\u308b\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u6297\u8840\u5c0f\u677f\u85ac\uff12\u5264\u4f75\u7528\u7642\u6cd5\uff08DAPT\uff09\u3001\u307b\u3068\u3093\u3069\u304c\u30a2\u30b9\u30d4\u30ea\u30f3\u3068\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u6025\u6027\u5fc3\u7b4b\u6897\u585e\u306e\u60a3\u8005\u3067\u300175\u6b73\u4ee5\u4e0a\u3084\u6297\u51dd\u56fa\u85ac\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u307e\u305f\u306f\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u85ac\u306e\u4f75\u7528\u3001\u304a\u3088\u3073\u30d8\u30ea\u30b3\u30d0\u30af\u30bf\u30fc\u30d4\u30ed\u30ea\u611f\u67d3\u306e\u4eba\u3092\u9ad8\u30ea\u30b9\u30af\u306e\u60a3\u8005\u3068\u3057\u3066\u9664\u5916\u3057\u3001\u6700\u7d42\u7684\u306b\u6d88\u5316\u7ba1\u51fa\u8840\u30ea\u30b9\u30af\u304c\u4f4e\u304417,247\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n\n\n\n\n
\u81e8\u5e8a\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/strong><\/th>\nPPI\u3042\u308a\uff08\uff05\uff09<\/strong><\/th>\nPPI\u306a\u3057\u3001\uff08\uff05\uff09<\/strong><\/th>\n\u8abf\u6574OR\uff0895% CI\uff09<\/strong><\/th>\n<\/tr>\n<\/thead>\n
\u6d88\u5316\u7ba1\u51fa\u8840<\/td>\n122 (1.1%)<\/td>\n10 (0.2%)<\/td>\n5.574 (2.902-10.697)<\/span><\/td>\n<\/tr>\n
\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8<\/td>\n568 (5.0%)<\/td>\n271 (4.7%)<\/td>\n1.026 (0.877-1.203)<\/td>\n<\/tr>\n
\u5168\u539f\u56e0\u6b7b\u4ea1<\/td>\n471 (4.1%)<\/td>\n248 (4.3%)<\/td>\n0.938 (0.791-1.112)<\/td>\n<\/tr>\n
\u5fc3\u7b4b\u6897\u585e<\/td>\n61 (0.5%)<\/td>\n16 (0.3%)<\/td>\n1.529 (0.872-2.678)<\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\n69 (0.6%)<\/td>\n16 (0.3%)<\/td>\n2.125 (1.216-3.682)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u3001\u6297\u8840\u5c0f\u677f\u85ac\uff12\u5264\u4f75\u7528\u7642\u6cd5\u306bPPI\u3092\u4f75\u7528\u3059\u308b\u3068\u3001\u6d88\u5316\u7ba1\u51fa\u8840\u306e\u53ef\u80fd\u6027\u304c\u306a\u3093\u3068\u7d045.6\u500d\u306b\u306a\u308a\u307e\u3059\u3002PPI\u306f\u6d88\u5316\u7ba1\u51fa\u8840\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u76ee\u7684\u3067\u306f\u306a\u304b\u3063\u305f\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u9006\u306b\u6d88\u5316\u7ba1\u51fa\u8840\u5897\u3048\u3066\u308b\u3084\u306a\u3044\u304b\u30fc\u3044\uff01\u305d\u3057\u3066\u3001\u3055\u3089\u306b\u8133\u5352\u4e2d\u306e\u53ef\u80fd\u6027\u306f2.1\u500d\u3067\u3059\u3002\u3042\u3089\u3089\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n
\u81e8\u5e8a\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/th>\n30\u65e5<\/th>\n6\u30f6\u6708<\/th>\n1\u5e74<\/th>\n2\u5e74<\/th>\n<\/tr>\n
<\/th>\n\u8abf\u6574HR\uff0895% CI\uff09<\/th>\n\u8abf\u6574HR\uff0895% CI\uff09<\/th>\n\u8abf\u6574HR\uff0895% CI\uff09<\/th>\n\u8abf\u6574HR\uff0895% CI\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u6d88\u5316\u7ba1\u51fa\u8840<\/td>\n5.577 (2.903-10.696)<\/span><\/td>\n4.988 (2.742-9.069)<\/span><\/td>\n4.331 (2.488-7.563)<\/span><\/td>\n3.650 (2.188-6.082)<\/span><\/td>\n<\/tr>\n
\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8<\/td>\n1.049 (0.905-1.211)<\/td>\n1.070 (0.934-1.225)<\/td>\n1.095 (0.963-1.246)<\/td>\n1.123 (0.994-1.270)<\/td>\n<\/tr>\n
\u5168\u539f\u56e0\u6b7b\u4ea1<\/td>\n0.965 (0.822-1.131)<\/td>\n0.945 (0.817-1.096)<\/td>\n0.940 (0.817-1.083)<\/td>\n0.971 (0.848-1.112)<\/td>\n<\/tr>\n
\u5fc3\u7b4b\u6897\u585e<\/td>\n1.297 (0.855-1.968)<\/td>\n1.580 (1.102-2.265)<\/span><\/td>\n1.812 (1.296-2.536)<\/span><\/td>\n1.773 (1.301-2.412)<\/span><\/td>\n<\/tr>\n
\u8133\u5352\u4e2d<\/td>\n2.202 (1.287-3.763)<\/span><\/td>\n2.270 (1.401-3.675)<\/span><\/td>\n2.261 (1.454-3.515)<\/span><\/td>\n2.072 (1.388-3.091)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

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PPI\u306e\u4f75\u7528\u306f\u80c3\u8178\u4fdd\u8b77\u52b9\u679c\u3092\u793a\u305b\u305a\u3001\u6d88\u5316\u7ba1\u51fa\u8840\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u5352\u4e2d\u3092\u5897\u52a0\u3055\u305b\u3066\u3044\u307e\u3059\u3002PPI\u304c\u6297\u8840\u5c0f\u677f\u4f5c\u7528\u3092\u6e1b\u5f31\u3055\u305b\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u3002\u672c\u672b\u8ee2\u5012\u3067\u3059\u306d\u3002<\/p>\n

\u3055\u3059\u304c\u30b9\u30bf\u30c1\u30f3\u3068\u4e26\u3076\u30de\u30c3\u30c1\u30dd\u30f3\u30d7\u85ac\u3067\u3059\u3002<\/p>\n

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\u300cThe Clinical Impact of Proton Pump Inhibitors When Co-Administered With Dual Antiplatelet Therapy in Patients Having Acute Myocardial Infarction With Low Risk of Gastrointestinal Bleeding: Insights From the China Acute Myocardial Infarction Registry\u300d<\/span><\/p>\n

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