{"id":28310,"date":"2024-12-03T05:57:42","date_gmt":"2024-12-02T20:57:42","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=28310"},"modified":"2024-12-03T05:57:42","modified_gmt":"2024-12-02T20:57:42","slug":"%e4%b8%80%e9%83%a8%e3%81%ae%e9%ab%98%e8%a1%80%e5%9c%a7%e3%81%ae%e8%96%ac%e3%81%af%e8%85%8e%e8%87%93%e3%82%92%e7%97%85%e7%9a%84%e3%81%aa%e7%8a%b6%e6%85%8b%e3%81%ab%e5%a4%89%e5%8c%96%e3%81%95%e3%81%9b-2","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=28310","title":{"rendered":"\u4e00\u90e8\u306e\u9ad8\u8840\u5727\u306e\u85ac\u306f\u814e\u81d3\u3092\u75c5\u7684\u306a\u72b6\u614b\u306b\u5909\u5316\u3055\u305b\u308b\u3000\u305d\u306e2"},"content":{"rendered":"<p>\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=28275\" target=\"_blank\" rel=\"noopener\">\u305d\u306e1<\/a>\u300d\u306e\u7d9a\u304d\u3067\u3059\u3002<\/p>\n<p>\u9ad8\u8840\u5727\u3067\u306f\u3001\u30ec\u30cb\u30f3\u5024\u306f\u7d0460\uff05\u3067\u6b63\u5e38\u3001\u7d0425\uff05\u3067\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23087856\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u3064\u307e\u308a\u3001\u9ad8\u8840\u5727\u60a3\u8005\u306e\u5927\u591a\u6570\u306f\u3001\u9ad8\u30ec\u30cb\u30f3\u5024\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u308c\u306a\u306e\u306b\u30ec\u30cb\u30f3\u3092\u963b\u5bb3\u3059\u308bRAS\u963b\u5bb3\u85ac\u304c\u3053\u3053\u307e\u3067\u983b\u7e41\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u8208\u5473\u6df1\u3044\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u9ad8\u8840\u5727\u3068\u8a00\u3048\u3070\u6162\u6027\u75be\u60a3\u306e\u4ee3\u8868\u3067\u3059\u304b\u3089\u3001\u305a\u3063\u3068\u85ac\u3092\u98f2\u307f\u7d9a\u3051\u307e\u3059\u3002<\/p>\n<p>RAS\u963b\u5bb3\u85ac\u306b\u9650\u3063\u305f\u7814\u7a76\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u8840\u5727\u3092\u5927\u304d\u304f\u4e0b\u3052\u308b\u5f37\u5316\u6cbb\u7642\uff08\u53ce\u7e2e\u671f\u8840\u5727\u76ee\u6a19\u3092120 mmHg\u672a\u6e80\uff09\u30b0\u30eb\u30fc\u30d7\u3068\u6a19\u6e96\u6cbb\u7642\uff08140 mmHg\u672a\u6e80\uff09\u30b0\u30eb\u30fc\u30d7\u3092\u6bd4\u8f03\u3057\u305f\u7814\u7a76\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26551272\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u3067\u3001\u4e3b\u8981\u8907\u5408\u30a2\u30a6\u30c8\u30ab\u30e0\uff08\u5fc3\u7b4b\u6897\u585e\u3001\u305d\u306e\u4ed6\u306e\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u4e0d\u5168\u3001\u307e\u305f\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\uff09\u306e\u767a\u751f\u7387\u306f\u78ba\u304b\u306b\u3001\u5f37\u5316\u6cbb\u7642\u30b0\u30eb\u30fc\u30d7\u306e\u65b9\u304c\u4f4e\u304f\u30011.65%\/\u5e74\u5bfe2.19%\/\u5e74\u3068\u7d76\u5bfe\u7684\u306a\u9055\u3044\u306f0.5\uff05\u307b\u3069\u306e\u9055\u3044\u3067\u3057\u305f\u3002\u3068\u3053\u308d\u304c\u305d\u306e\u4e00\u65b9\u3067\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u6162\u6027\u814e\u81d3\u75c5\u3067\u306f\u306a\u304b\u3063\u305f\u4eba\u306e\u3046\u3061\u3001\u7cf8\u7403\u4f53\u308d\u904e\u91cf\uff08eGFR\uff09\u304c60ml\/\u5206\u672a\u6e80\u306e\u5024\u307e\u306730%\u4ee5\u4e0a\u4f4e\u4e0b\u3057\u305f\u30b1\u30fc\u30b9\u306f\u3001\u6a19\u6e96\u6cbb\u7642\u7fa4\uff080.35%\/\u5e74\uff09\u3088\u308a\u3082\u5f37\u5316\u6cbb\u7642\u7fa4\uff081.21%\/\u5e74\uff09\u3067\u591a\u304f\u8a8d\u3081\u3089\u308c\u3001\u5f37\u5316\u6cbb\u7642\u7fa4\u306e\u814e\u6a5f\u80fd\u4f4e\u4e0b\u306e\u30ea\u30b9\u30af\u306f3.49\u500d\u3067\u3057\u305f\u3002\u3055\u3089\u306b\u5168\u4f53\u3067\u306f\u3001\u6a19\u6e96\u6cbb\u7642\u7fa4\u3088\u308a\u3082\u5f37\u5316\u6cbb\u7642\u7fa4\u3067\u6025\u6027\u814e\u969c\u5bb3\u307e\u305f\u306f\u6025\u6027\u814e\u4e0d\u5168\u304c1.66\u500d\u591a\u304f\u898b\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u3089\u3059\u306e\u3067\u3042\u308c\u3070\u3001\u814e\u81d3\u304f\u3089\u3044\u72a0\u7272\u306b\u3057\u3066\u3082\u826f\u3044\u3068\u3067\u3082\u601d\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u30a2\u30e1\u30ea\u30ab\u4eba\u306b\u304a\u3051\u308b5\u7a2e\u985e\u306e\u964d\u5727\u85ac\u306e\u4f7f\u7528\u3068\u6162\u6027\u814e\u81d3\u75c5\u306e\u30b9\u30c6\u30fc\u30b8\u3068\u306e\u95a2\u4fc2\u3092\u5206\u6790\u3057\u305f\u7814\u7a76\uff08<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2018\/1382705\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u3067\u306f\u30012009\uff5e2012\u5e74\u306b\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac (ARB) \u3067\u6cbb\u7642\u3057\u305f\u60a3\u8005\u3067\u306f\u3001ARB\u3067\u6cbb\u7642\u3057\u306a\u304b\u3063\u305f\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u3001\u9032\u884c\u671f (\u30b9\u30c6\u30fc\u30b83\u30014\u30015 \u306e\u5408\u8a08) \u306e\u6162\u6027\u814e\u81d3\u75c5\u306e\u53ef\u80fd\u6027\u304c2.52\u500d\u3068\u6709\u610f\u306b\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u9032\u884c\u3057\u305f\u6162\u6027\u814e\u81d3\u75c5\u306e\u60a3\u8005\u306eRAS\u963b\u5bb3\u85ac\u3092\u4e2d\u6b62\u3057\u3066\u307f\u305f\u7814\u7a76\u30922\u3064\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u30021\u3064\u76ee\u306e\u7814\u7a76\uff08<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2210639\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u306f\u3001eGFR\u304c30\u672a\u6e80\u306e411\u4eba\u3092RAS\u963b\u5bb3\u85ac\u3092\u4e2d\u6b62\u3057\u305f\u7fa4\u3068\u7d99\u7d9a\u3057\u305f\u7fa4\u306b\u5206\u3051\u30663\u5e74\u5f8c\u3069\u3046\u306a\u308b\u304b\u898b\u3066\u307f\u307e\u3057\u305f\u3002\u7d50\u679c\u306f\u3001RAS\u963b\u5bb3\u5264\u306e\u6295\u4e0e\u4e2d\u6b62\u306f\u3001eGFR\u306e\u9577\u671f\u4f4e\u4e0b\u7387\u306b\u304a\u3044\u3066\u30b0\u30eb\u30fc\u30d7\u9593\u306e\u6709\u610f\u5dee\u3068\u306f\u95a2\u9023\u304c\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u672b\u671f\u814e\u4e0d\u5168\u307e\u305f\u306f\u814e\u4ee3\u66ff\u7642\u6cd5\u306e\u767a\u751f\u3082\u9055\u3044\u306f\u306a\u304f\u3001\u4e2d\u6b62\u7fa4\u3068\u7d99\u7d9a\u7fa4\u3067\u306f\u3001\u3042\u3089\u3086\u308b\u7406\u7531\u306b\u3088\u308b\u5165\u9662\u4ef6\u6570\u304c\u540c\u7a0b\u5ea6\u3067\u3042\u308a\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u4ef6\u6570\u3082\u540c\u69d8\u3067\u3057\u305f\u3002\u3055\u3089\u306b\u6b7b\u4ea1\u4ef6\u6570\u3082\u540c\u69d8\u3067\u3057\u305f\u3002<\/p>\n<p>\u307e\u305f\u3001\u6700\u521d\u306e15\u304b\u6708\u9593\u306f\u3001\u4e2d\u6b62\u7fa4\u306e\u53ce\u7e2e\u671f\u8840\u5727\u3068\u62e1\u5f35\u671f\u8840\u5727\u306f\u3044\u305a\u308c\u3082\u7d99\u7d9a\u7fa4\u3088\u308a\u3082\u9ad8\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u5f8c\u3001\u8840\u5727\u5024\u306f2\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u540c\u7a0b\u5ea6\u3068\u306a\u308a\u3001\u8a66\u9a13\u4e2d\u306b\u51e6\u65b9\u3055\u308c\u305f\u964d\u5727\u85ac\u306e\u6570\u3082\u540c\u69d8\u3067\u3057\u305f\u3002\u6700\u521d\u306e1\u5e74\u9593\u3001\u4e2d\u6b62\u7fa4\u3067\u306f\u5c3f\u4e2d\u30bf\u30f3\u30d1\u30af\u8cea\uff1a\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u6bd4\u304c\u4e00\u6642\u7684\u306b\u4e0a\u6607\u3057\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u5f8c\u306f\u7fa4\u9593\u5dee\u306f\u7121\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u5fc3\u8840\u7ba1\u3001\u8840\u7ba1\u3001\u304a\u3088\u3073\u5fc3\u4e0d\u5168\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306e\u6570\u3082\u30012\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u540c\u7a0b\u5ea6\u3067\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u7d50\u679c\u3092\u898b\u308b\u3068\u3001\u672c\u5f53\u306b\u814e\u4fdd\u8b77\u4f5c\u7528\u304c\u3042\u308b\u306e\u304b\u7591\u554f\u3067\u3059\u3057\u3001\u3053\u306e\u85ac\u306e\u5fc5\u8981\u6027\u3082\u7591\u554f\u3067\u3059\u306d\u3002<\/p>\n<p>\u3082\u3046\u4e00\u3064\u7814\u7a76\u3067\u3059\u3002\uff08<a href=\"https:\/\/academic.oup.com\/ndt\/article-abstract\/25\/12\/3977\/1862962\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u9032\u884c\u6027\u6162\u6027\u814e\u81d3\u75c5\uff08\u30b9\u30c6\u30fc\u30b84\u304a\u3088\u30735\uff09\u306e\u60a3\u800552\u4eba\u304c\u5bfe\u8c61\u3067\u3001\u5e73\u5747\u5e74\u9f6273.3\u6b73\u3001eGFR\u306f16.38\u3002\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u5c3f\u30bf\u30f3\u30d1\u30af\u8cea\uff1a\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u6bd4\uff08PCR\uff09\u306f77mg\/mmol\u300246%\u304c\u7cd6\u5c3f\u75c5\u3067\u3057\u305f\u3002\u305d\u3057\u3066RAS\u963b\u5bb3\u85ac\u3092\u4e2d\u6b62\u3057\u300112\u304b\u6708\u9593\u8ffd\u8de1\u3057\u307e\u3057\u305f\u3002\u814e\u6a5f\u80fd\u306f\u3069\u3046\u306a\u3063\u305f\u3067\u3057\u3087\u3046\u3002\uff08\u56f3\u306f\u3053\u306e\u8ad6\u6587\u3088\u308a\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/11\/5ad6e8500c7c55ddfc48c926d714bd7b.png\"><img 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