{"id":29178,"date":"2025-01-22T08:34:50","date_gmt":"2025-01-21T23:34:50","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=29178"},"modified":"2025-01-22T08:34:50","modified_gmt":"2025-01-21T23:34:50","slug":"%e7%b3%96%e5%b0%bf%e7%97%85%e8%96%ac%ef%bc%9f%e3%82%84%e3%81%9b%e8%96%ac%ef%bc%9fglp-1%e5%8f%97%e5%ae%b9%e4%bd%93%e4%bd%9c%e5%8b%95%e8%96%ac%e3%81%ae%e5%89%af%e4%bd%9c%e7%94%a8%e3%80%80%e3%81%9d-11","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=29178","title":{"rendered":"\u7cd6\u5c3f\u75c5\u85ac\uff1f\u3084\u305b\u85ac\uff1fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u3000\u305d\u306e11\u3000\u3046\u3064\u75c5\u3001\u4e0d\u5b89\u3001\u81ea\u6bba\u884c\u52d5\u306e\u30ea\u30b9\u30af"},"content":{"rendered":"

GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u30b7\u30ea\u30fc\u30ba\u3082\u300c\u305d\u306e11\u300d\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u300c\u305d\u306e2<\/a>\u300d\u3084\u300cGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u81ea\u6bba\u5ff5\u616e\u306e\u30ea\u30b9\u30af<\/a>\u300d\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u81ea\u6bba\u30ea\u30b9\u30af\u3068\u95a2\u9023\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u80a5\u6e80\u60a3\u8005\u306b\u304a\u3051\u308b\u3046\u3064\u75c5\u3001\u4e0d\u5b89\u3001\u81ea\u6bba\u884c\u52d5\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u3067\u3059\u3002\u5bfe\u8c61\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u51e6\u65b9\u3055\u308c\u305f\u80a5\u6e80\u306e\u4eba162,257\u4eba\u3068\u5bfe\u7167\u7fa4\u3068\u3057\u3066GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u51e6\u65b9\u3055\u308c\u3066\u3044\u306a\u3044\u80a5\u6e80162,257\u4eba\u3067\u3059\u3002\u904e\u53bb1\u5e74\u4ee5\u5185\u306b\u53cc\u6975\u6027\u969c\u5bb3\u3001\u7d71\u5408\u5931\u8abf\u75c7\u3001\u3046\u3064\u75c5\u3001\u4e0d\u5b89\u75c7\u3001\u81ea\u6bba\u5ff5\u616e\u307e\u305f\u306f\u81ea\u6bba\u4f01\u56f3\u304c\u3042\u3063\u305f\u4eba\u306f\u9664\u5916\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5e73\u5747\u5e74\u9f62\u306f\u7d0452\u6b73\u3067\u3059\u3002<\/p>\n

\n

\u4e0b\u306e\u8868\u306fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4f7f\u7528\u3057\u305f\u80a5\u6e80\u60a3\u8005\u306e\u7cbe\u795e\u533b\u5b66\u7684\u8ee2\u5e30\u3067\u3059\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<\/div>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u65e5\u4ee5\u964d\u306e\u30a4\u30d9\u30f3\u30c8\u306e\u7d2f\u7a4d\u767a\u751f\u7387<\/th>\n<\/th>\n<\/th>\n<\/tr>\n
<\/th>\n6\u30f6\u6708<\/th>\n1\u5e74<\/th>\n3\u5e74<\/th>\n5\u5e74<\/th>\n\u30cf\u30b6\u30fc\u30c9\u6bd4\uff0895% CI\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u5168\u3066\u306e\u7cbe\u795e\u75be\u60a3<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u3000GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n9.36%<\/td>\n15.29%<\/td>\n29.62%<\/td>\n39.64%<\/td>\n1.98(1.94-2.01)<\/span><\/td>\n<\/tr>\n
\u3000\u975eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n4.76%<\/td>\n7.63%<\/td>\n16.45%<\/td>\n23.38%<\/td>\n1<\/td>\n<\/tr>\n
\u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u3000GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n1.41%<\/td>\n2.38%<\/td>\n4.99%<\/td>\n7.02%<\/td>\n2.95(2.82-3.08)<\/span><\/td>\n<\/tr>\n
\u3000\u975eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n0.36%<\/td>\n0.66%<\/td>\n1.67%<\/td>\n2.68%<\/td>\n1<\/td>\n<\/tr>\n
\u4e0d\u5b89<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u3000GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n6.35%<\/td>\n10.69%<\/td>\n21.68%<\/td>\n30.03%<\/td>\n2.08(2.04-2.12)<\/span><\/td>\n<\/tr>\n
\u3000\u975eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n3.09%<\/td>\n4.98%<\/td>\n11.16%<\/td>\n16.45%<\/td>\n1<\/td>\n<\/tr>\n
\u81ea\u6bba\u5ff5\u616e\u307e\u305f\u306f\u81ea\u6bba\u4f01\u56f3<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u3000GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n0.22%<\/td>\n0.42%<\/td>\n1.45%<\/td>\n3.64%<\/td>\n2.06(1.92-2.21)<\/span><\/td>\n<\/tr>\n
\u3000\u975eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/td>\n0.21%<\/td>\n0.35%<\/td>\n0.89%<\/td>\n1.42%<\/td>\n1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u30016\u304b\u6708\u304b\u30895\u5e74\u307e\u3067\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u4f7f\u7528\u8005\u306e\u69d8\u3005\u306a\u7cbe\u795e\u75be\u60a3\u306a\u3069\u304c\u4e00\u8cab\u3057\u3066\u5897\u52a0\u3057\u307e\u3057\u305f\u3002GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u4eba\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001\u5168\u3066\u306e\u7cbe\u795e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306f1.98\u500d\u3001\u3046\u3064\u75c5\u306f2.95\u500d\u3001\u4e0d\u5b89\u306f2.08\u500d\u3001\u81ea\u6bba\u5ff5\u616e\u307e\u305f\u306f\u81ea\u6bba\u4f01\u56f3\u306f2.06\u500d\u3067\u3059\u3002<\/p>\n

\n

\u4e0b\u306e\u8868\u306f\u5e74\u9f62\u3001\u6027\u5225\u3001\u4eba\u7a2e\u5225\u306b\u5206\u3051\u305f\u7cbe\u795e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002<\/p>\n<\/div>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7<\/th>\n\u5168\u3066\u306e\u7cbe\u795e\u75be\u60a3<\/th>\n\u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3<\/th>\n\u4e0d\u5b89<\/th>\n\u81ea\u6bba\u5ff5\u616e\u307e\u305f\u306f\u81ea\u6bba\u4f01\u56f3<\/th>\n<\/tr>\n<\/thead>\n
\u6027\u5225<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0 \u5973\u6027<\/td>\n2.05(2.01\u20132.09)<\/span><\/td>\n3.16(2.98\u20133.34)<\/span><\/td>\n2.19(2.14\u20132.24)<\/span><\/td>\n2.53(2.32\u20132.76)<\/span><\/td>\n<\/tr>\n
\u00a0 \u7537\u6027<\/td>\n1.77(1.72\u20131.83)<\/span><\/td>\n2.89(2.63\u20133.19)<\/span><\/td>\n1.89(1.82\u20131.96)<\/span><\/td>\n1.70(1.50\u20131.92)<\/span><\/td>\n<\/tr>\n
\u5e74<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0 18\uff5e49\u6b73<\/td>\n2.01(1.96\u20132.07)<\/span><\/td>\n2.34(2.15\u20132.55)<\/span><\/td>\n2.16(2.09\u20132.24)<\/span><\/td>\n3.01(2.70\u20133.37)<\/span><\/td>\n<\/tr>\n
\u00a0 50\uff5e69\u6b73<\/td>\n1.78(1.73\u20131.83)<\/span><\/td>\n2.44(2.25\u20132.64)<\/span><\/td>\n1.89(1.83\u20131.95)<\/span><\/td>\n2.40(2.13\u20132.71)<\/span><\/td>\n<\/tr>\n
\u00a0 \u2265 70<\/td>\n1.71(1.61\u20131.82)<\/span><\/td>\n2.49(2.07\u20132.99)<\/span><\/td>\n1.81(1.67\u20131.95)<\/span><\/td>\n1.65(1.21\u20132.27)<\/span><\/td>\n<\/tr>\n
\u4eba\u7a2e<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u00a0 \u767d\u4eba<\/td>\n1.92(1.89\u20131.96)<\/span><\/td>\n3.03(2.87\u20133.21)<\/span><\/td>\n2.03(1.99\u20132.08)<\/span><\/td>\n2.18(2.01\u20132.36)<\/span><\/td>\n<\/tr>\n
\u00a0 \u9ed2\u4eba<\/td>\n2.18(2.08\u20132.28)<\/span><\/td>\n2.76(2.41\u20133.16)<\/span><\/td>\n2.37(2.25\u20132.50)<\/span><\/td>\n3.45(2.86\u20134.17)<\/span><\/td>\n<\/tr>\n
\u00a0 \u30a2\u30b8\u30a2\u4eba<\/td>\n1.78(1.57\u20132.02)<\/span><\/td>\n1.89(1.28\u20132.79)<\/span><\/td>\n1.98(1.71\u20132.29)<\/span><\/td>\n0.87(0.49\u20131.54)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u4f7f\u7528\u8005\u306e\u4e2d\u3067\u3001\u5973\u6027\u306e\u65b9\u304c\u7537\u6027\u3088\u308a\u3082\u3055\u307e\u3056\u307e\u306a\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u5e74\u9f62\u5225\u3067\u306f\u300118\uff5e49\u6b73\u3068\u3044\u3046\u82e5\u5e74\u5c64\u306e\u65b9\u304c\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u4eba\u7a2e\u5225\u3067\u306f\u3001\u6211\u3005\u30a2\u30b8\u30a2\u4eba\u306f\u3001\u3084\u3084\u30ea\u30b9\u30af\u304c\u4f4e\u3081\u3067\u3001\u81ea\u6bba\u5ff5\u616e\u307e\u305f\u306f\u81ea\u6bba\u4f01\u56f3\u306b\u95a2\u3057\u3066\u306f\u6709\u610f\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3067\u3082\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8003\u3048\u308b\u3068\u6cb9\u65ad\u306f\u7981\u7269\u3067\u3059\u3002<\/p>\n

GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u8133\u306b\u3082\u50cd\u304d\u3001\u8133\u306e\u5831\u916c\u7cfb\u306b\u4f5c\u7528\u3057\u3066\u3001\u30c9\u30d1\u30df\u30f3\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u304c\u4f4e\u4e0b\u3055\u305b\u3066\u3001\u98df\u6b32\u3092\u6291\u5236\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09\u30c9\u30d1\u30df\u30f3\u306f\u4eba\u9593\u304c\u89e6\u308c\u3066\u306f\u3044\u3051\u306a\u3044\u9818\u57df\u3067\u3059\u3002\u30c9\u30d1\u30df\u30f3\u3092\u523a\u6fc0\u3059\u308c\u3070\u3001\u4f9d\u5b58\u3084\u885d\u52d5\u884c\u52d5\u3001\u7570\u5e38\u884c\u52d5\u306b\u7d50\u3073\u3064\u304d\u307e\u3059\u3057\u3001\u30c9\u30d1\u30df\u30f3\u306e\u4f4e\u4e0b\u306f\u3046\u3064\u3084\u4e0d\u5b89\u3092\u8d77\u3053\u3057\u3001\u305d\u3057\u3066\u81ea\u6bba\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n

\u3053\u3093\u306a\u5371\u967a\u306a\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308b\u30ea\u30b9\u30af\u307e\u3067\u8ca0\u3063\u3066\u3001\u3053\u306e\u85ac\u3092\u4f7f\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u304b\uff1f\u5b89\u6613\u306b\u85ac\u3092\u4f7f\u3048\u3070\u3001\u305d\u306e\u4ee3\u511f\u306f\u975e\u5e38\u306b\u5927\u304d\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u7cd6\u5c3f\u75c5\u306b\u3082\u4f53\u91cd\u6e1b\u5c11\u306b\u3082\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002<\/p>\n

\u300cThe risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy\u300d<\/span><\/p>\n

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