{"id":29255,"date":"2025-04-01T18:46:18","date_gmt":"2025-04-01T09:46:18","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=29255"},"modified":"2025-04-01T18:46:18","modified_gmt":"2025-04-01T09:46:18","slug":"%e6%ad%a2%e3%82%81%e3%82%8b%e3%81%aa%e5%8d%b1%e9%99%ba%ef%bc%9f%e5%b0%bf%e9%85%b8%e5%80%a4%e3%82%92%e4%b8%8b%e3%81%92%e3%82%8b%e8%96%ac%e3%81%ae%e6%8a%95%e4%b8%8e%e4%b8%ad%e6%ad%a2%e3%81%af%e6%8a%95","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=29255","title":{"rendered":"\u6b62\u3081\u308b\u306a\u5371\u967a\uff1f\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u85ac\u306e\u6295\u4e0e\u4e2d\u6b62\u306f\u6295\u4e0e\u7d99\u7d9a\u3088\u308a\u3082\u6b7b\u4ea1\u7387\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b"},"content":{"rendered":"<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=7382\" target=\"_blank\" 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href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35732345\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\u3001\u4e0b\u306e\u56f3\u3082\u3053\u3053\u304b\u3089\uff09CARES \u8a66\u9a13\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3066\u3001\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u307e\u305f\u306f\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u306e\u6295\u4e0e\u4e2d\u6b62\u306b\u3088\u308a\u3001\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8 (MACE) \u304a\u3088\u3073 \u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u304c\u5897\u52a0\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>6190\u4eba\u306e\u60a3\u8005\u306e\u3046\u3061\u3001\u85ac\u6295\u4e0e\u4e2d\u306bMACE\u304c\u767a\u751f\u3057\u305f\u306e\u306f448\u4eba (7.2%)\u3001\u85ac\u4e2d\u6b62\u5f8c\u306b\u306f208\u4eba (3.3%) 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\/><\/a><\/p>\n<p>\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u307e\u305f\u306f\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u306e\u6295\u4e0e\u958b\u59cb\u524d2\u5e74\u4ee5\u5185\u304a\u3088\u3073\u6295\u4e0e\u958b\u59cb\u5f8c2\u5e74\u4ee5\u5185\u306b\u767a\u751f\u3057\u305f\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08\u6025\u6027\u5fc3\u7b4b\u6897\u585e\uff083538\u4eba\uff09\u3001\u8133\u6897\u585e\uff085127\u4eba\uff09\u3001\u8133\u51fa\u8840\uff081593\u4eba\uff09\uff09\u306b\u3088\u308b\u5165\u9662\u3092\u7279\u5b9a\u3057\u307e\u3057\u305f\u3002\u4e0a\u306e\u56f3\u306e\u3088\u3046\u306b\u3001\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u307e\u305f\u306f\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u306e\u6295\u4e0e\u958b\u59cb\u524d2\u5e74\u9593\u306b\u767a\u751f\u3057\u305f\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306f4333\u4ef6\uff081\u4eba\u6642\u9593\u3042\u305f\u308a0.014\uff09\u3067\u3001\u6295\u4e0e\u958b\u59cb\u524d30\u65e5\u9593\u306b\u767a\u751f\u3057\u305f\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306f1032\u4ef6\uff081\u4eba\u6642\u9593\u3042\u305f\u308a0.081\uff09\u3067\u3057\u305f\u3002\u307e\u305f\u3001\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u307e\u305f\u306f\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u306e\u6295\u4e0e\u958b\u59cb\u5f8c7\u65e5\u4ee5\u5185\u306b\u300183\u4ef6\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff081\u4eba\u6642\u9593\u3042\u305f\u308a0.030\uff09\u304c\u767a\u751f\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u3068\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u306f\u901a\u5e38\u3001\u6025\u6027\u75db\u98a8\u767a\u4f5c\u306e\u6570\u9031\u9593\u5f8c\u306b\u958b\u59cb\u3055\u308c\u308b\u3053\u3068\u3092\u8003\u616e\u3059\u308c\u3070\u3001\u6295\u4e0e\u958b\u59cb\u524d30\u65e5\u9593\u306b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u5927\u304d\u304f\u5897\u52a0\u3059\u308b\u3053\u3068\u306f\u3001\u5f53\u7136\u306e\u3088\u3046\u306b\u601d\u3048\u307e\u3059\u3002\u75db\u98a8\u767a\u4f5c\u306f\u5f37\u3044\u708e\u75c7\u3092\u8d77\u3053\u3057\u307e\u3059\u304b\u3089\u3002\u3057\u304b\u3057\u3001\u85ac\u958b\u59cb\u5f8c7\u65e5\u4ee5\u5185\u3067\u3055\u3048\u3001\u901a\u5e38\u6642\u306e\u304a\u3088\u305d2\u500d\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u8d77\u3053\u3059\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u85ac\u3067\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u3053\u3068\u306e\u5371\u967a\u6027\u3082\u8003\u3048\u308b\u5fc5\u8981\u304c\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u85ac\u306f\u59cb\u3081\u308b\u3068\u304d\u3082\u5371\u967a\u3001\u6b62\u3081\u308b\u3068\u304d\u306f\u3082\u3063\u3068\u5371\u967a\u3002\u305d\u3046\u3067\u3042\u308b\u306a\u3089\u3070\u3001\u59cb\u3081\u306a\u3044\u65b9\u304c\u826f\u3044\u3067\u3057\u3087\u3046\u3002\u59cb\u3081\u3066\u3057\u307e\u3048\u3070\u3001\u4e00\u751f\u533b\u7642\u306b\u4f9d\u5b58\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u304b\u306d\u307e\u305b\u3093\u3002<\/p>\n<p>\u305d\u308c\u3068\u3082\u3046\u4e00\u3064\u3001\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u85ac\u3092\u98f2\u307f\u59cb\u3081\u308b\u3068\u3001\u75db\u98a8\u767a\u4f5c\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4f55\u304b\u8a50\u6b3a\u307f\u305f\u3044\u306a\u8a71\u3067\u3059\u3088\u306d\u3002\u5c3f\u9178\u304c\u9ad8\u3044\u3068\u75db\u98a8\u306b\u306a\u308b\u3068\u56f0\u308b\u304b\u3089\u85ac\u3092\u98f2\u307f\u59cb\u3081\u305f\u3089\u3001\u9006\u306b\u75db\u98a8\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u304b\u3089\u3002\u5c3f\u9178\u5024\u304c\u6025\u6fc0\u306b\u4f4e\u4e0b\u3059\u308b\u3068\u3001\u95a2\u7bc0\u6db2\u4e2d\u306e\u7d50\u6676\u584a\u306e\u7d50\u5408\u304c\u3086\u308b\u304f\u306a\u308a\u3001\u7d50\u6676\u304c\u8131\u843d\u3057\u3066\u75db\u98a8\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u308b\u305d\u3046\u3067\u3059\u304c\u3001\u672c\u5f53\u306e\u3068\u3053\u308d\u306e\u6a5f\u5e8f\u306f\u4e0d\u660e\u306a\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u4e0b\u306e\u56f3\u306f\u30d5\u30a7\u30d6\u30ea\u30af\u306e\u6dfb\u4ed8\u6587\u66f8\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u3082\u306e\u3067\u3059\u30020\uff5e2\u9031\u3067\u306f\u30d5\u30a7\u30d6\u30ea\u30af\u3092\u98f2\u3093\u3060\u65b9\u304c\u75db\u98a8\u95a2\u7bc0\u708e\u3092\u8d77\u3053\u3057\u3084\u3059\u304f\u30012\uff5e6\u9031\u3067\u306f\u30d7\u30e9\u30bb\u30dc\u306e\u65b9\u304c\u767a\u73fe\u5272\u5408\u306f\u9ad8\u304f\u306a\u308a\u307e\u3059\u304c\u30016\uff5e10\u9031\u3067\u306f\u518d\u5ea6\u9006\u8ee2\u3057\u3001\u30d5\u30a7\u30d6\u30ea\u30af\u306e\u65b9\u304c\u75db\u98a8\u3092\u8d77\u3053\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u300210\uff5e16\u9031\u3067\u306f40mg\u3060\u3068\u30d5\u30a7\u30d6\u30ea\u30af\u304c3\u500d\u8fd1\u3044\u767a\u73fe\u7387\u3067\u3059\u30022\u9031\u9593\u3054\u3068\u304f\u3089\u3044\u306b\u5897\u91cf\u3057\u3066\u3082\u3053\u3093\u306a\u3082\u306e\u3067\u3059\u3002<\/p>\n<table border=\"1\" cellpadding=\"3\">\n<caption>\n<div>\u75db\u98a8\u95a2\u7bc0\u708e\u306e\u767a\u73fe\u5272\u5408<\/div>\n<\/caption>\n<tbody>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">\u6295\u4e0e\u7fa4<\/td>\n<td colspan=\"1\" rowspan=\"1\">0\u301c2\u9031\u4ee5\u4e0b<\/td>\n<td colspan=\"1\" rowspan=\"1\">2\u9031\u8d856\u9031\u4ee5\u4e0b<\/td>\n<td colspan=\"1\" rowspan=\"1\">6\u9031\u8d8510\u9031\u4ee5\u4e0b<\/td>\n<td colspan=\"1\" rowspan=\"1\">10\u9031\u8d8516\u9031\u4ee5\u4e0b<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">\u30d7\u30e9\u30bb\u30dc\uff0838\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">0.0\uff05<\/td>\n<td colspan=\"1\" rowspan=\"1\">5.3\uff05<\/td>\n<td colspan=\"1\" rowspan=\"1\">2.6\uff05<\/td>\n<td colspan=\"1\" rowspan=\"1\">2.7\uff05<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">20mg\/\u65e5\uff0843\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"4\">0.6\uff05\uff0810mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"4\">2.5\uff05\uff0820mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">4.9\uff05\uff0820mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">2.4\uff05\uff0820mg\/\u65e5\uff09<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">40mg\/\u65e5\uff0841\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"3\">3.4\uff05\uff0840mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">7.5\uff05\uff0840mg\/\u65e5\uff09<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">60mg\/\u65e5\uff0836\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">8.8\uff05\uff0860mg\/\u65e5\uff09<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">80mg\/\u65e5\uff0841\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">17.9\uff05\uff0880mg\/\u65e5\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u3055\u3089\u306b\u3001\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u3068\u30d5\u30a7\u30d6\u30ea\u30af\u3092\u6bd4\u8f03\u3057\u305f\u306e\u304c\u4e0b\u306e\u8868\u3067\u3059\u3002<\/p>\n<table border=\"1\" cellpadding=\"3\">\n<caption>\n<div>\u75db\u98a8\u95a2\u7bc0\u708e\u306e\u767a\u73fe\u5272\u5408<\/div>\n<\/caption>\n<tbody>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">\u6295\u4e0e\u7fa4<\/td>\n<td colspan=\"1\" rowspan=\"1\">0\u301c12\u65e5\u4ee5\u4e0b<\/td>\n<td colspan=\"1\" rowspan=\"1\">12\u65e5\u8d856\u9031\u4ee5\u4e0b<\/td>\n<td colspan=\"1\" rowspan=\"1\">6\u9031\u8d858\u9031\u4ee5\u4e0b<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb200mg\/\u65e5\uff08121\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">1.7\uff05\uff08100mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">3.3\uff05\uff08200mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">0.9\uff05\uff08200mg\/\u65e5\uff09<\/td>\n<\/tr>\n<tr>\n<td colspan=\"1\" rowspan=\"1\">\u672c\u526440mg\/\u65e5\uff08122\u4f8b\uff09<\/td>\n<td colspan=\"1\" rowspan=\"1\">1.6\uff05\uff0810mg\/\u65e5\uff09<\/td>\n<td colspan=\"1\" 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