{"id":30148,"date":"2025-04-18T08:25:44","date_gmt":"2025-04-17T23:25:44","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=30148"},"modified":"2025-04-18T08:25:44","modified_gmt":"2025-04-17T23:25:44","slug":"iga%e8%85%8e%e7%97%87%e3%81%a8%e6%96%b0%e5%9e%8b%e3%82%b3%e3%83%ad%e3%83%8a%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%a8%e7%b3%96%e8%b3%aa%e9%81%8e%e5%89%b0%e6%91%82%e5%8f%96","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=30148","title":{"rendered":"IgA\u814e\u75c7\u3068\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3068\u7cd6\u8cea\u904e\u5270\u6442\u53d6"},"content":{"rendered":"

IgA\u814e\u75c7\u306f\u3001\u691c\u5c3f\u3067\u8840\u5c3f\u3084\u305f\u3093\u3071\u304f\u5c3f\u3092\u8a8d\u3081\u3001\u814e\u81d3\u306e\u7cf8\u7403\u4f53\u306bIgA\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u304c\u6c88\u7740\u3059\u308b\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3067\u3001\u591a\u304f\u306f\u6162\u6027\u306b\u7d4c\u904e\u3057\u307e\u3059\u3002<\/p>\n

\u305d\u306eIgA\u814e\u75c7\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u975e\u5e38\u306b\u591a\u304f\u767a\u751f\u3057\u305f\u308a\u3001\u60aa\u5316\u3057\u305f\u308a\u3057\u3066\u3044\u307e\u3059\u3002\u4ee5\u524d\u306b\u8a18\u4e8b\u300c\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306f\u814e\u969c\u5bb3\u3092\u3082\u305f\u3089\u3059\u3000\u4ed6\u306e\u30ef\u30af\u30c1\u30f3\u3082\u3054\u6ce8\u610f\u3092<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u65e5\u672c\u814e\u81d3\u5b66\u4f1a\u306f\u300c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\uff08COVID-19\uff09\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066<\/a>\u300d\u3068\u3044\u3046\u6587\u66f8\u3092\u51fa\u3057\u3066\u3001\u305d\u306e\u4e2d\u3067\u3001\u3042\u308b\u610f\u5473\u63a8\u5968\u3068\u3044\u3046\u7acb\u5834\u3092\u793a\u3057\u306a\u304c\u3089\u3001\u300c\u5b9f\u969b\u306b\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u4e3b\u6cbb\u533b\u3068\u3054\u76f8\u8ac7\u4e0b\u3055\u3044\u300d\u3068\u8a00\u3063\u3066\u3001\u73fe\u5834\u306b\u4e38\u6295\u3052\u3057\u3066\u3001\u5b66\u4f1a\u3068\u3057\u3066\u306f\u8cac\u4efb\u3092\u8ca0\u308f\u306a\u3044\u3088\u3046\u306a\u59ff\u52e2\u306b\u3082\u898b\u3048\u307e\u3057\u305f\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u4e00\u65b9\u3067\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u8089\u773c\u7684\u8840\u5c3f\u51fa\u73fe\u306e\u95a2\u9023\u6027\u306b\u95a2\u3059\u308b\u8abf\u67fb\u7814\u7a76<\/a>\u300d\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u30cd\u30d5\u30ed\u30fc\u30bc\u75c7\u5019\u7fa4\u65b0\u898f\u767a\u75c7\u30fb\u518d\u767a\u306e\u95a2\u9023\u6027\u306b\u95a2\u3059\u308b\u8abf\u67fb\u7814\u7a76<\/a>\u300d\u3068\u3044\u3046\u8abf\u67fb\u3092\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u5f53\u3067\u3042\u308c\u3070\u3001\u8abf\u67fb\u3060\u3051\u3067\u306a\u304f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u6b62\u3081\u308b\u3053\u3068\u304c\u5148\u3067\u306f\u306a\u304b\u3063\u305f\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u88ab\u5bb3\u304c\u5e83\u304c\u3089\u306a\u3044\u3088\u3046\u306b\u3001\u305d\u308c\u4ee5\u4e0a\u306e\u63a5\u7a2e\u306f\u307e\u305a\u306f\u6b62\u3081\u3066\u3001\u3068\u3044\u3046\u3079\u304d\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u65e5\u672c\u4eba\u306f\u30ef\u30af\u30c1\u30f3\u306e\u5b9f\u9a13\u53f0\u306e\u3088\u3046\u306b\u3055\u308c\u3001IgA\u814e\u75c7\u304c\u8d77\u304d\u3066\u3044\u3066\u3082\u63a5\u7a2e\u306f\u7d9a\u884c\u3055\u308c\u3001\u7814\u7a76\u3084\u8ad6\u6587\u306e\u30cd\u30bf\u306b\u3055\u308c\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u65e5\u672c\u304b\u3089\u306e\u8ad6\u6587\u3060\u3051\u3067\u3082\u5c11\u306a\u304f\u3068\u3082\u6b21\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u63a2\u305b\u3070\u3082\u3063\u3068\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\uff09<\/p>\n

\u30fb\u300cAn adolescent presenting with IgA nephropathy and persistent decreased kidney function after COVID-19 vaccination during follow-up for asymptomatic hematuria: a clinicopathological study\u300d<\/span><\/p>\n

\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u7121\u75c7\u5019\u6027\u8840\u5c3f\u306e\u8ffd\u8de1\u8abf\u67fb\u4e2d\u306bIgA\u814e\u75c7\u3068\u6301\u7d9a\u6027\u814e\u6a5f\u80fd\u4f4e\u4e0b\u3092\u5448\u3057\u305f\u9752\u5e74\uff1a\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u7814\u7a76\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cAdverse reactions and effects on renal function of COVID-19 vaccines in patients with IgA nephropathy\u300d<\/span><\/p>\n

\u300cIgA\u814e\u75c7\u60a3\u8005\u306b\u304a\u3051\u308bCOVID-19\u30ef\u30af\u30c1\u30f3\u306e\u526f\u4f5c\u7528\u3068\u814e\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cSecondary immunoglobulin A nephropathy with gross hematuria leading to rapidly progressive glomerulonephritis following severe acute respiratory syndrome coronavirus 2 vaccination: a case report\u300d<\/span><\/p>\n

\u300c\u91cd\u75c7\u6025\u6027\u547c\u5438\u5668\u75c7\u5019\u7fa4\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b92\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u8089\u773c\u7684\u8840\u5c3f\u3092\u4f34\u3046\u4e8c\u6b21\u6027\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3A\u814e\u75c7\u304c\u6025\u901f\u9032\u884c\u6027\u7cf8\u7403\u4f53\u814e\u708e\u3092\u767a\u75c7\u3057\u305f\u75c7\u4f8b\u5831\u544a\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cComparison of renal histopathology in three patients with gross hematuria after SARS-CoV-2 vaccination\u300d<\/span><\/p>\n

\u300cSARS-CoV-2\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u8089\u773c\u7684\u8840\u5c3f\u3092\u5448\u3057\u305f3\u540d\u306e\u60a3\u8005\u306b\u304a\u3051\u308b\u814e\u81d3\u7d44\u7e54\u75c5\u7406\u5b66\u7684\u6bd4\u8f03\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cRapidly progressive IgA nephropathy with membranoproliferative glomerulonephritis-like lesions in an elderly man following the third dose of an mRNA COVID-19 vaccine: a case report\u300d<\/span><\/p>\n

\u300c\u9ad8\u9f62\u7537\u6027\u306b\u304a\u3051\u308bmRNA COVID-19\u30ef\u30af\u30c1\u30f3\u306e3\u56de\u76ee\u306e\u63a5\u7a2e\u5f8c\u306b\u819c\u6027\u5897\u6b96\u6027\u7cf8\u7403\u4f53\u814e\u708e\u69d8\u75c5\u5909\u3092\u4f34\u3046\u6025\u901f\u9032\u884c\u6027IgA\u814e\u75c7\u3092\u767a\u75c7\u3057\u305f\u75c7\u4f8b\u5831\u544a\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cAssociation between COVID-19 vaccination and relapse of glomerulonephritis\u300d<\/span><\/p>\n

\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u7cf8\u7403\u4f53\u814e\u708e\u306e\u518d\u767a\u3068\u306e\u95a2\u9023\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cDevelopment of IgA vasculitis with severe glomerulonephritis after COVID-19 vaccination: a case report and literature review\u300d<\/span><\/p>\n

\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u91cd\u75c7\u7cf8\u7403\u4f53\u814e\u708e\u3092\u4f34\u3046IgA\u8840\u7ba1\u708e\u3092\u767a\u75c7\u3057\u305f\u75c7\u4f8b\u5831\u544a\u3068\u6587\u732e\u30ec\u30d3\u30e5\u30fc\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cSibling cases of gross hematuria and newly diagnosed IgA nephropathy following SARS-CoV-2 vaccination\u300d<\/span><\/p>\n

\u300cSARS-CoV-2\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u8089\u773c\u7684\u8840\u5c3f\u3068\u65b0\u305f\u306bIgA\u814e\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5144\u5f1f\u306e\u75c7\u4f8b\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cIgA nephropathy with glomerular capillary IgA deposition following SARS-CoV-2 mRNA vaccination: a report of three cases\u300d<\/span><\/p>\n

\u300cSARS-CoV-2 mRNA\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u7cf8\u7403\u4f53\u6bdb\u7d30\u8840\u7ba1IgA\u6c88\u7740\u3092\u4f34\u3046IgA\u814e\u75c7\uff1a3\u75c7\u4f8b\u306e\u5831\u544a\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cGross hematuria can be an impact of severe acute respiratory syndrome coronavirus 2 vaccination on immunoglobulin A nephropathy: a case report\u300d<\/span><\/p>\n

\u300c\u91cd\u75c7\u6025\u6027\u547c\u5438\u5668\u75c7\u5019\u7fa4\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b92\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u304c\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3A\u814e\u75c7\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3068\u3057\u3066\u8089\u773c\u7684\u8840\u5c3f\u304c\u307f\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff1a\u75c7\u4f8b\u5831\u544a\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cIgA Nephropathy with Gross Hematuria Following COVID-19 mRNA Vaccination\u300d<\/span><\/p>\n

\u300cCOVID-19 mRNA\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u8089\u773c\u7684\u8840\u5c3f\u3092\u4f34\u3046IgA\u814e\u75c7\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u30fb\u300cAn adolescent girl diagnosed with IgA nephropathy following the first dose of the COVID-19 vaccine\u300d<\/span><\/p>\n

\u300cCOVID-19\u30ef\u30af\u30c1\u30f3\u306e\u521d\u56de\u63a5\u7a2e\u5f8c\u306bIgA\u814e\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305f10\u4ee3\u306e\u5c11\u5973\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

\u5b66\u4f1a\u306e\u5b58\u5728\u610f\u7fa9\u306f\u3001\u60a3\u8005\u5074\u306b\u5229\u76ca\u304c\u3042\u3063\u3066\u3053\u305d\u3067\u3042\u308b\u306f\u305a\u3067\u3057\u3087\u3046\u3002\u4eca\u306e\u533b\u7642\u306e\u4e16\u754c\u306f\u7570\u5e38\u3067\u3059\u3002<\/p>\n

\u3055\u3066\u4eca\u56de\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u308b\u3082\u306e\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u304c\u3001IgA\u814e\u75c7\u3068\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u306e\u8a18\u4e8b\u3067\u3059\u3002<\/p>\n

\u79c1\u306f\u3001\u6162\u6027\u814e\u81d3\u75c5\u306b\u306f\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u6162\u6027\u814e\u81d3\u75c5\u306b\u5bfe\u3059\u308b\u7cd6\u8cea\u5236\u9650<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u7cd6\u8cea\u5236\u9650\u304c\u6709\u52b9\u3001\u5fc5\u8981\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306eIgA\u814e\u75c7\u3068\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u95a2\u9023\u306f\u3069\u3046\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u307e\u305a\u306fIgA\u814e\u75c7\u3068\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u4ee3\u8868\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u3068\u306e\u95a2\u9023\u3067\u3059\u3002<\/p>\n

IgA\u814e\u75c7\u60a3\u8005698\u4eba\uff08\u5e73\u5747\u5e74\u9f6235.83\u6b73\u3001\u7537\u602751.86%\uff09\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u4e0b\u306e\u8868\u3082\u3053\u3053\u3088\u308a\u6539\u5909\uff09\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306e\u69cb\u6210\u8981\u7d20\u306e\u6570\u306b\u3088\u308a\u3001\u30b0\u30eb\u30fc\u30d7A\uff08\u69cb\u6210\u8981\u7d20\u306a\u3057\uff09\u3001\u30b0\u30eb\u30fc\u30d7B\uff08\u69cb\u6210\u8981\u7d201\u3064\uff09\u3001\u30b0\u30eb\u30fc\u30d7C\uff08\u69cb\u6210\u8981\u7d202\u3064\uff09\u3001\u30b0\u30eb\u30fc\u30d7D\uff08\u69cb\u6210\u8981\u7d203\u3064\uff09\u3001\u30b0\u30eb\u30fc\u30d7E\uff08\u69cb\u6210\u8981\u7d204\u3064\u4ee5\u4e0a\uff09\u306e5\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\u307e\u3057\u305f\u3002<\/p>\n

\n

\u4e0b\u306e\u8868\u306f\u3001\u4ee3\u8b1d\u7570\u5e38\u306e\u306a\u3044\u30b0\u30eb\u30fc\u30d7A\u3068\u6bd4\u8f03\u3057\u305f\u3001\u305d\u306e\u4ed6\u306e\u30b0\u30eb\u30fc\u30d7\u306e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u30a4\u30d9\u30f3\u30c8\u3092\u7d4c\u9a13\u3059\u308b\u30ea\u30b9\u30af\u3067\u3059\u3002<\/p>\n<\/div>\n

\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u5358\u5909\u91cf<\/th>\n\u591a\u5909\u91cf<\/th>\n<\/tr>\n
HR (95%CI)<\/th>\nHR (95%CI)<\/th>\n<\/tr>\n<\/thead>\n
\u30b0\u30eb\u30fc\u30d7B\uff08\u5bfe\u30b0\u30eb\u30fc\u30d7A\uff09<\/td>\n2.475 (1.127\u20135.433)<\/span><\/td>\n<\/td>\n<\/tr>\n
\u30b0\u30eb\u30fc\u30d7C\uff08\u5bfe\u30b0\u30eb\u30fc\u30d7A\uff09<\/td>\n3.185 (1.467\u20136.915)<\/span><\/td>\n<\/td>\n<\/tr>\n
\u30b0\u30eb\u30fc\u30d7D\uff08\u5bfe\u30b0\u30eb\u30fc\u30d7A\uff09<\/td>\n4.093 (1.852\u20139.044)<\/span><\/td>\n<\/td>\n<\/tr>\n
\u30b0\u30eb\u30fc\u30d7E\uff08\u5bfe\u30b0\u30eb\u30fc\u30d7A\uff09<\/td>\n6.814 (2.914\u201315.934)<\/span><\/td>\n4.030 (1.675\u20139.693)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

124\u4eba\u306e\u60a3\u8005\u304c\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3092\u7d4c\u9a13\u3057\u3001\u305d\u306e\u3046\u306112\u4eba\u304c\u6b7b\u4ea1\u300193\u4eba\u304c\u8907\u5408\u814e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\uff08\u672b\u671f\u814e\u75be\u60a3\u307e\u305f\u306f\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u500d\u5897\uff09\u300119\u4eba\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u7d4c\u9a13\u3057\u307e\u3057\u305f\u3002\u4ee3\u8b1d\u7570\u5e38\u306e\u306a\u3044IgA\u814e\u75c7\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30e1\u30bf\u30dc\u306e\u69cb\u6210\u8981\u7d20\u306e\u6570\u304c\u5897\u52a0\u3059\u308b\u306b\u3064\u308c\u3001\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u30014\u3064\u4ee5\u4e0a\u306e\u4ee3\u8b1d\u6210\u5206\u306e\u7d44\u307f\u5408\u308f\u305b\u3092\u6301\u3064\u60a3\u8005\u306f\u3001\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u30a4\u30d9\u30f3\u30c8\u3092\u7d4c\u9a13\u3059\u308b\u30ea\u30b9\u30af\u304c4.030\u500d\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u3064\u307e\u308a\u3001\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u3001IgA\u814e\u75c7\u306e\u4e88\u5f8c\u304c\u60aa\u304f\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u5225\u306e\u7814\u7a76\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3002\u56f3\u3082\u3053\u3053\u3088\u308a\uff09IgA\u814e\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305f\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u30b9\u30c6\u30fc\u30b8 1\uff5e4 \u306e\u60a3\u8005145 \u4eba (\u7537\u6027 92 \u4eba\u3001\u5973\u6027 53 \u4eba\u3001\u5e74\u9f62 54.7\u6b73) \u3092\u691c\u67fb\u3057\u3001\u5e73\u5747190 \u304b\u6708\u306b\u308f\u305f\u308a\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u4e3b\u8981\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u3001\u5168\u539f\u56e0\u6b7b\u4ea1\u3068\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8840\u884c\u518d\u5efa\u8853\u306a\u3069\u306e\u3042\u3089\u3086\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3067\u3057\u305f\u3002\u4e8c\u6b21\u5fc3\u8840\u7ba1\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u3042\u3089\u3086\u308b\u8840\u884c\u518d\u5efa\u8853\u306a\u3069\u306e\u3042\u3089\u3086\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3067\u3057\u305f\u3002\u4e8c\u6b21\u814e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u3001\u672b\u671f\u814e\u75be\u60a3\u3078\u306e\u5230\u9054\u3068\u814e\u4ee3\u66ff\u7642\u6cd5\u306e\u958b\u59cb\u3067\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u3001\u5de6\u304b\u3089\u4e3b\u8981\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u5fc3\u8840\u7ba1\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u814e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3067\u9752\u3044\u7dda\u304c\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306a\u3057\u3001\u8d64\u3044\u7dda\u304c\u30e1\u30bf\u30dc\uff08\uff0b\uff09\u3067\u3059\u3002\u660e\u3089\u304b\u306b\u30e1\u30bf\u30dc\u3092\u4f34\u3046IgA\u814e\u75c7\u60a3\u8005\u3068\u4f34\u308f\u306a\u3044IgA\u814e\u75c7\u60a3\u8005\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u4e3b\u8981\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u5fc3\u8840\u7ba1\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u814e\u81d3\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306b\u6709\u610f\u5dee\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u6b21\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u6307\u6a19\u3001TyG\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u3068\u306e\u95a2\u9023\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3002\u56f3\u3082\u3053\u3053\u3088\u308a\uff09IgA\u814e\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305f1210\u4eba\uff08\u5e73\u5747\u5e74\u9f6232\u6b73\uff09\u304c\u5bfe\u8c61\u3067\u3059\u3002\u814e\u6a5f\u80fd\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u3001eGFR\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u5024\u304b\u3089\u306e50%\u4ee5\u4e0a\u306e\u4f4e\u4e0b\u3001\u672b\u671f\u814e\u4e0d\u5168\uff08ESKD\uff09\u3001\u814e\u79fb\u690d\u304a\u3088\u3073\uff0f\u307e\u305f\u306f\u6b7b\u4ea1\u3068\u3057\u3001ESKD\u306f\u3001eGFR\u304c15 mL\/\u5206\/1.73 m 2\u4ee5\u4e0b\u307e\u305f\u306f\u7dad\u6301\u814e\u4ee3\u66ff\u7642\u6cd5\u3068\u5b9a\u7fa9\u3057\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306fTyG > 8.72\u3067\u5206\u3051\u305f\u3068\u304d\u306e\u814e\u751f\u5b58\u7387\u3067\u3059\u3002TyG\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u304c\u9ad8\u3044\u7fa4\u3067\u306f\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306e\u767a\u751f\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u9ad8\u3044TyG\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u306fIgA\u814e\u75c7\u306e\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3078\u306e\u9032\u884c\u30ea\u30b9\u30af\u304c2.654\u500d\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304cIgA\u814e\u75c7\u306e\u60aa\u5316\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u3082\u3046\u4e00\u3064\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3068\u306e\u95a2\u9023\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3002\u56f3\u3082\u3053\u3053\u3088\u308a\uff09IgA\u814e\u75c7\u306e174\u4eba\u306e\u60a3\u8005\u304c\u5bfe\u8c61\u3067\u3001\u814e\u751f\u691c\u3067IgA\u814e\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u3066\u304b\u308911\u5e74\u5f8c\u306816\u5e74\u5f8c\u306b\u691c\u67fb\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u9032\u884c\u6027IgA\u814e\u75c7\u306f\u3001\u30b7\u30b9\u30bf\u30c1\u30f3C\u304c\u6b63\u5e38\u7bc4\u56f2\u3092\u8d85\u3048\u3001\u6700\u521d\u306e\u53d7\u8a3a\u3068 2 \u56de\u76ee\u306e\u53d7\u8a3a\u306e\u9593\u306b20%\u3092\u8d85\u3048\u308b\u4e0a\u6607\u3092\u793a\u3059\u5834\u5408\u3001\u307e\u305f\u306f\u814e\u79fb\u690d\u307e\u305f\u306f\u900f\u6790\u306e\u958b\u59cb\u3068\u5b9a\u7fa9\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

2\u56de\u76ee\u306e\u8a3a\u5bdf\u6642\u306b\u60a3\u8005\u306e19.5\uff05\u3067IgA\u814e\u75c7\u304c\u9032\u884c\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\u4e0a\u306e\u56f3\u306f\u521d\u56de\u8a3a\u5bdf\u6642\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u30ec\u30d9\u30eb\u3068HOMA-IR\u306fIgA\u814e\u75c7\u306e\u9032\u884c\u3068\u306e\u95a2\u9023\u3067\u3059\u3002A\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u3001B\u306fHOMA-IR\u3067\u3059\u3002\u5de6\u5074\u304c\u5b89\u5b9a\u3057\u305fIgA\u814e\u75c7\u3001\u53f3\u5074\u304c\u9032\u884c\u6027IgA\u814e\u75c7\u3067\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u30ec\u30d9\u30eb\u3068HOMA-IR\u306f\u3069\u3061\u3089\u3082IgA\u814e\u75c7\u306e\u9032\u884c\u3068\u6709\u610f\u306a\u95a2\u9023\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n

IgA\u814e\u75c7\u306e\u6b63\u78ba\u306a\u75c5\u56e0\u306f\u4f9d\u7136\u3068\u3057\u3066\u4e0d\u660e\u3067\u3059\u3002IgA\u814e\u75c7\u3067\u306f\u5185\u76ae\u7d30\u80de\u306e\u640d\u5931\u304c\u767a\u751f\u3057\u3001\u305d\u308c\u304cIgA\u814e\u75c7\u306e\u9032\u884c\u306b\u5bc4\u4e0e\u3057\u3001\u8840\u7ba1\u5185\u76ae\u969c\u5bb3\u306f\u7cf8\u7403\u4f53\u969c\u5bb3\u306e\u4e3b\u8981\u306a\u539f\u56e0\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

IgA\u814e\u75c7\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u969c\u5bb3\u306e\u7279\u7570\u7684\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308b\u8840\u6f3f\u30d5\u30a9\u30f3\u30fb\u30f4\u30a3\u30ec\u30d6\u30e9\u30f3\u30c9\u56e0\u5b50\uff08vWF\uff09\u304a\u3088\u3073\u8840\u7ba1\u53ce\u7e2e\u6027\u30a8\u30f3\u30c9\u30bb\u30ea\u30f3-1\uff08ET-1\uff09\u306e\u4e0a\u6607\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u8840\u7ba1\u5185\u76ae\u5897\u6b96\u56e0\u5b50\uff08VEGF\uff09\u30a2\u30f3\u30bf\u30b4\u30cb\u30b9\u30c8\u3067\u3042\u308b\u53ef\u6eb6\u6027fms\u69d8\u30c1\u30ed\u30b7\u30f3\u30ad\u30ca\u30fc\u30bc-1\uff08sFlt-1\uff09\u306f\u3001\u598a\u5a20\u9ad8\u8840\u5727\u75c7\u5019\u7fa4\u306b\u304a\u3051\u308b\u5185\u76ae\u6a5f\u80fd\u969c\u5bb3\u306e\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u591a\u304f\u306e\u7814\u7a76\u3067\u3001\u904e\u5270\u306asFlt-1\u306f\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u60a3\u8005\u306e\u5185\u76ae\u6a5f\u80fd\u969c\u5bb3\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u524d\u306e\u7814\u7a76\u3067\u306f\u3001IgA\u814e\u75c7\u60a3\u8005\u306b\u304a\u3044\u3066sFlt-1\u5024\u304c\u4e0a\u6607\u3057\u3066\u304a\u308a\u3001\u30bf\u30f3\u30d1\u30af\u5c3f\u3001\u9ad8\u8840\u5727\u3001vWF\u5024\u3068\u3082\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n

\u305d\u3057\u3066\u3001\u9ad8\u8840\u7cd6\u306fsFlt-1\u3001ET-1\u3001vWF\u3092\u3059\u3079\u3066\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\uff08\u3053\u3053<\/a>\u3068\u3053\u3053<\/a>\u3068\u3053\u3053<\/a>\u3068\u3053\u3053<\/a>\u3068\u3053\u3053<\/a>\u306a\u3069\u53c2\u7167\uff09\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5897\u3084\u3057\u3001\u8840\u7ba1\u5185\u76ae\u969c\u5bb3\u3092\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n

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