{"id":30369,"date":"2025-05-19T08:46:00","date_gmt":"2025-05-18T23:46:00","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=30369"},"modified":"2025-05-19T08:46:00","modified_gmt":"2025-05-18T23:46:00","slug":"sglt2%e9%98%bb%e5%ae%b3%e8%96%ac%e3%81%a8glp-1%e5%8f%97%e5%ae%b9%e4%bd%93%e4%bd%9c%e5%8b%95%e8%96%ac%e3%81%af%e7%b3%96%e5%b0%bf%e7%97%85%e6%82%a3%e8%80%85%e3%81%ae%e8%bb%a2%e5%80%92%e3%82%92%e5%a2%97","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=30369","title":{"rendered":"SGLT2\u963b\u5bb3\u85ac\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8ee2\u5012\u3092\u5897\u52a0\u3055\u305b\u308b"},"content":{"rendered":"

\u4ee5\u524d\u306e\u8a18\u4e8b\u300cGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u3088\u308b\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u3068\u9aa8\u7c97\u9b06\u75c7<\/a>\u300d\u3067\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u3088\u308a\u7b4b\u8089\u304c\u5927\u304d\u304f\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002\u300c\u7cd6\u5c3f\u75c5\u306b\u304a\u3044\u3066GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3084SGLT-2\u963b\u5bb3\u85ac\u3067\u8d77\u3053\u308b\u7b4b\u8089\u91cf\u306e\u6e1b\u5c11<\/a>\u300d\u3067\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3060\u3051\u3067\u306a\u304f\u3001SGLT2\u963b\u5bb3\u85ac\u3067\u3082\u7b4b\u8089\u306e\u6e1b\u5c11\u304c\u8d77\u304d\u308b\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u7b4b\u8089\u306e\u6e1b\u5c11\u306f\u8ee2\u5012\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304a\u3088\u3073SGLT2\u963b\u5bb3\u85ac\u30682\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8ee2\u5012\u3068\u306e\u95a2\u9023\u6027\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002\u6b69\u884c\u3084\u65e5\u5e38\u751f\u6d3b\u52d5\u4f5c\u306b\u5b8c\u5168\u306b\u81ea\u7acb\u3057\u3066\u3044\u308b2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005471\u4eba\uff08\u5e73\u5747\u5e74\u9f6263 \u6b73\uff09\u3092\u5bfe\u8c61\u3067\u3001\u8ffd\u8de1\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f2\u5e74\u3067\u8ee2\u5012\u767a\u751f\u7387\u306f100\u4eba\u5e74\u3042\u305f\u308a17.1\u4eba\u3067\u3057\u305f\u300215\u4eba\u304c\u8ee2\u5012\u306b\u3088\u308a\u9aa8\u6298\u3092\u7d4c\u9a13\u3057\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n
\n
\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n\u30e2\u30c7\u30eb1<\/th>\n<\/tr>\n<\/thead>\n
SGLT2\u963b\u5bb3\u85ac\/\u4e21\u85ac\u5264\u3068\u3082\u4f7f\u7528\u3057\u306a\u3044<\/td>\n1.80 (1.10\u20132.92)<\/span><\/td>\n<\/tr>\n
GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\/\u4e21\u85ac\u5264\u3068\u3082\u4f7f\u7528\u3057\u306a\u3044<\/td>\n1.61 (0.88\u20132.84)<\/td>\n<\/tr>\n
SGLT2\u963b\u5bb3\u85ac\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4f75\u7528\/\u4e21\u85ac\u5264\u3068\u3082\u4f7f\u7528\u3057\u306a\u3044<\/td>\n2.89 (1.27\u20136.56)<\/span><\/p>\n

\uff080.992\uff09<\/span><\/td>\n<\/tr>\n

\u5165\u9662\u6642\u306e\u8ee2\u5012\u6b74<\/td>\n2.26 (1.57\u20133.26)<\/span><\/td>\n<\/tr>\n
\u6027\u5225\uff08\u5973\u6027\/\u7537\u6027\uff09<\/td>\n1.73 (1.03\u20132.89)<\/span><\/td>\n<\/tr>\n
\u5e74<\/td>\n1.02 (1.01\u20131.04)<\/span><\/td>\n<\/tr>\n
\u8eab\u9577<\/td>\n1.00 (0.97\u20131.03)<\/td>\n<\/tr>\n
BMI<\/td>\n1.02 (0.99\u20131.06)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u3001\u8ee2\u5012\u306e\u53ef\u80fd\u6027\u306fGLP-1\u85ac\u306e\u670d\u7528\u306f\u6709\u610f\u306a\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002SGLT2\u963b\u5bb3\u85ac\u306e\u4f7f\u7528\u306f1.80\u500d\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068SGLT2\u963b\u5bb3\u85ac\u306e\u4f75\u7528\u306f2.89\u500d\u3067\u3057\u305f\u3002<\/p>\n

\u8ee2\u5012\u6b74\u306f2.26\u500d\u3001\u5973\u6027\u306f1.73\u500d\u3067\u3057\u305f\u3002<\/p>\n

SGLT2\u963b\u5bb3\u5264\u306f\u5c3f\u91cf\u3092\u5897\u52a0\u3055\u305b\u308b\u305f\u3081\u3001\u4f53\u6db2\u91cf\u304c\u6e1b\u308a\u3001\u6392\u5c3f\u983b\u5ea6\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u983b\u5c3f\u3001\u7279\u306b\u591c\u9593\u983b\u5c3f\u306f\u8ee2\u5012\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u4f53\u6db2\u91cf\u6e1b\u5c11\u306f\u8d77\u7acb\u6027\u4f4e\u8840\u5727\u306e\u5371\u967a\u56e0\u5b50\u3067\u3042\u308a\u3001\u8ee2\u5012\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u4e21\u85ac\u5264\u306b\u3088\u308b\u7b4b\u8089\u306e\u6e1b\u5c11\u3082\u8ee2\u5012\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u4eca\u56de\u306e\u7814\u7a76\u306e\u7d50\u679c\u306e\u3088\u3046\u306b\u3001\u4e21\u85ac\u5264\u3092\u4f75\u7528\u3059\u308b\u3068\u3055\u3089\u306b\u8ee2\u5012\u306e\u5371\u967a\u304c\u5897\u52a0\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n

\u85ac\u306b\u3088\u3063\u3066\u8840\u7cd6\u5024\u304c\u4f4e\u4e0b\u3057\u3001\u4f53\u91cd\u304c\u6e1b\u5c11\u3057\u3066\u3001\u559c\u3093\u3067\u3044\u308b\u5834\u5408\u3067\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u7279\u306b\u9ad8\u9f62\u306b\u306a\u3063\u3066\u304f\u308b\u3068\u3001\u8ee2\u5012\u306f\u9aa8\u6298\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u7b4b\u529b\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3057\u3001\u8ee2\u5012\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u305f\u3081\u306b\u3001\u9069\u5207\u306a\u98df\u4e8b\u7642\u6cd5\u3068\u904b\u52d5\u7642\u6cd5\u3092\u5b9f\u65bd\u3059\u3079\u304d\u3067\u3042\u308b\u3001\u3068\u8a00\u3046\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u305d\u3046\u3067\u3042\u308b\u306a\u3089\u3070\u6700\u521d\u304b\u3089\u85ac\u306a\u3057\u3067\u3001\u98df\u4e8b\u7642\u6cd5\u3068\u904b\u52d5\u3067\u5341\u5206\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u9069\u5207\u306a\u98df\u4e8b\u7642\u6cd5\u3068\u3044\u3046\u306e\u304c\u30011\u65e53\u56de\u304d\u3063\u3061\u308a\u3068\u3001\u30d0\u30e9\u30f3\u30b9\u306e\u826f\u3044\u98df\u4e8b\u3001\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u306a\u3069\u3068\u3044\u3046\u52b9\u679c\u306e\u4e4f\u3057\u3044\u98df\u4e8b\u3092\u63a8\u5968\u3057\u3066\u3044\u308b\u304b\u3089\u554f\u984c\u306a\u306e\u3067\u3059\u3002\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308c\u3070\u3001\u85ac\u306a\u3057\u3067\u8840\u7cd6\u5024\u306e\u4f4e\u4e0b\u3084\u4f53\u91cd\u6e1b\u5c11\u304c\u5f97\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u7cd6\u5c3f\u75c5\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u85ac\u306b\u983c\u3063\u3066\u3044\u3066\u306f\u3001\u526f\u4f5c\u7528\u306e\u5fc3\u914d\u304c\u7d76\u3048\u307e\u305b\u3093\u3002<\/p>\n

\u3068\u3053\u308d\u3067\u3001\u6628\u65e5\u3001\u30d5\u30eb\u30de\u30e9\u30bd\u30f3\u306e\u30ec\u30fc\u30b9\u304c\u3042\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u6570\u65e5\u524d\u304b\u3089\u53f3\u819d\u306e\u75db\u307f\u304c\u51fa\u73fe\u3057\u307e\u3057\u305f\u3002\u7279\u306b\u6b69\u304d\u51fa\u3057\u304c\u75db\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u3068\u308a\u3042\u3048\u305a\u30b7\u30c3\u30d7\u3092\u5f35\u3063\u3066\u69d8\u5b50\u3092\u898b\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u30ec\u30fc\u30b9\u5f53\u65e5\u307e\u3067\u75db\u307f\u306f\u5909\u308f\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3067\u3082\u3001\u305d\u306e\u307e\u307e\u8d70\u308a\u59cb\u3081\u3001\u30ec\u30fc\u30b9\u3092\u7d42\u3048\u308b\u3068\u3001\u3042\u3089\u4e0d\u601d\u8b70\u3001\u53f3\u819d\u306e\u75db\u307f\u306f\u6d88\u3048\u3066\u3044\u307e\u3057\u305f\u3002\u4ee5\u524d\u3082\u30d5\u30eb\u30de\u30e9\u30bd\u30f3\u524d\u65e5\u3084\u5bcc\u58eb\u5c71\u767b\u9802\u306e\u6570\u65e5\u524d\u306b\u304e\u3063\u304f\u308a\u8170\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u3044\u305a\u308c\u3082\u30ec\u30fc\u30b9\u3084\u767b\u5c71\u7d42\u4e86\u5f8c\u306b\u8170\u75db\u306f\u6d88\u5931\u3057\u3066\u3044\u307e\u3059\u3002\u4eba\u9593\u306e\u4f53\u3063\u3066\u9762\u767d\u3044\u3067\u3059\u3088\u306d\u3002\u533b\u7642\u3088\u308a\u3082\u904e\u9177\u306a\u904b\u52d5\u306e\u65b9\u304c\u52b9\u679c\u7684\u306a\u3093\u3066\u3002\u8133\u304c\u75db\u307f\u3088\u308a\u3082\u512a\u5148\u7684\u306b\u69d8\u3005\u306a\u904b\u52d5\u306b\u5fc5\u8981\u306a\u547d\u4ee4\u3092\u305a\u3063\u3068\u51fa\u3057\u3066\u3044\u308b\u3046\u3061\u306b\u3001\u75db\u307f\u306e\u4fe1\u53f7\u3092\u51fa\u3059\u3053\u3068\u3092\u5fd8\u308c\u3066\u3057\u307e\u3046\u306e\u3067\u3057\u3087\u3046\u304b\u306d\uff1f<\/p>\n

\u3067\u304d\u308b\u9650\u308a\u533b\u7642\u306b\u983c\u308b\u306e\u306f\u3084\u3081\u307e\u3057\u3087\u3046\u3002<\/p>\n

\u300cLongitudinal association of SGLT2 inhibitors and GLP-1RAs on falls in persons with type 2 diabetes\u300d<\/span><\/p>\n

\u300c2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8ee2\u5012\u306b\u5bfe\u3059\u308bSGLT2\u963b\u5bb3\u85ac\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u9577\u671f\u7684\u95a2\u9023\u6027\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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