{"id":30476,"date":"2025-05-28T08:49:37","date_gmt":"2025-05-27T23:49:37","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=30476"},"modified":"2025-05-28T08:49:37","modified_gmt":"2025-05-27T23:49:37","slug":"%e9%ab%98%e8%a1%80%e5%9c%a7%e3%81%ae%e8%96%ac%e3%82%a2%e3%83%b3%e3%82%b8%e3%82%aa%e3%83%86%e3%83%b3%e3%82%b7%e3%83%b3%e5%8f%97%e5%ae%b9%e4%bd%93%e6%8b%ae%e6%8a%97%e8%96%ac%ef%bc%88arb%ef%bc%89-2","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=30476","title":{"rendered":"\u9ad8\u8840\u5727\u306e\u85ac\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09\u306f\u672c\u5f53\u306b\u5fc5\u8981\u306a\u85ac\u304b\uff1f\u3000\u305d\u306e2"},"content":{"rendered":"

\u300c\u305d\u306e1<\/a>\u300d\u3067\u306f\u3001\u9ad8\u8840\u5727\u306e\u85ac\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09\u306e\u5fc3\u81d3\u306b\u5bfe\u3059\u308b\u52b9\u679c\u306f\u5168\u304f\u7121\u3044\u306b\u7b49\u3057\u304f\u3001\u9006\u306b\u5fc3\u8840\u7ba1\u6b7b\u304c\u5897\u52a0\u3059\u308b\u53ef\u80fd\u6027\u3059\u3089\u3042\u308b\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u3001\u814e\u81d3\u3078\u306e\u52b9\u679c\u3084\u305d\u306e\u4ed6\u306e\u6709\u5bb3\u4f5c\u7528\u306b\u3064\u3044\u3066\u3067\u3059\u3002<\/p>\n

\u814e\u81d3\u3078\u306e\u52b9\u679c\u306e\u7814\u7a76\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u56f3\u3082\u3053\u3053\u3088\u308a\u3001\u8868\u306f\u3053\u3053\u3088\u308a\u6539\u5909\uff09\u6b63\u5e38\u8840\u5727\u3067\u6b63\u5e38\u30a2\u30eb\u30d6\u30df\u30f3\u5c3f\u3092\u6709\u3059\u308b1\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005285\u4eba\u304c\u5bfe\u8c61\u3067\u3059\u3002\u60a3\u8005\u306f\u30ed\u30b5\u30eb\u30bf\u30f3\uff08ARB\u3001\u5546\u54c1\u540d\u30cb\u30e5\u30fc\u30ed\u30bf\u30f3\uff09\uff08100mg\/\u65e5\uff09\u3001\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\uff08\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff08ACE\uff09\u963b\u5bb3\u85ac\u3001\u5546\u54c1\u540d\u30ec\u30cb\u30d9\u30fc\u30b9\uff09\uff0820mg\/\u65e5\uff09\u3001\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u3092\u6295\u4e0e\u3055\u308c\u308b\u7fa4\u306b\u7121\u4f5c\u70ba\u306b\u5206\u3051\u3089\u308c\u30015\u5e74\u9593\u8ffd\u8de1\u3055\u308c\u307e\u3057\u305f\u3002\u814e\u75c7\u306e\u9032\u884c\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u3001\u814e\u751f\u691c\u6a19\u672c\u306b\u304a\u3051\u308b\u7cf8\u7403\u4f53\u5bb9\u7a4d\u306b\u5360\u3081\u308b\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u306e\u5272\u5408\u306e\u5909\u5316\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u306e\u7d50\u679c\u3001\u4e0b\u306e\u8868\u306e\u3088\u3046\u306b\u30015\u5e74\u9593\u306e\u7cf8\u7403\u4f53\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u5206\u753b\u5bb9\u7a4d\u306e\u5909\u5316\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\u7fa4\u307e\u305f\u306f\u30ed\u30b5\u30eb\u30bf\u30f3\u7fa4\u3068\u306e\u9593\u306b\u6709\u610f\u5dee\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001\u751f\u691c\u3067\u8a55\u4fa1\u3055\u308c\u305f\u305d\u306e\u4ed6\u306e\u814e\u69cb\u9020\u5909\u6570\u306b\u3064\u3044\u3066\u3082\u6709\u610f\u306a\u6cbb\u7642\u52b9\u679c\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
a. \u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u305f\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\u3068\u30ed\u30b5\u30eb\u30bf\u30f3\u306e\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u5206\u753b\u5bb9\u7a4d\u5909\u5316\u306b\u5bfe\u3059\u308b\u52b9\u679c\uff08\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u30895\u5e74\u5f8c\u306e\u751f\u691c\u307e\u3067\uff09<\/p>\n
\n<\/th>\n<\/tr>\n
<\/th>\n\u30d7\u30e9\u30bb\u30dc\uff08N=85\uff09<\/th>\n\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\uff08N=86\uff09<\/th>\n\u30ed\u30b5\u30eb\u30bf\u30f3\uff08N=85\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306e\u5e73\u5747\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u5206\u753b\u5bb9\u7a4d<\/td>\n0.187<\/td>\n0.201<\/td>\n0.189<\/td>\n<\/tr>\n
\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u5206\u753b\u5bb9\u7a4d\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u306e\u5e73\u5747\u5909\u5316<\/td>\n0.016<\/td>\n0.005<\/td>\n0.026<\/td>\n<\/tr>\n
\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u5909\u5316\u306e\u5dee<\/td>\n<\/tr>\n
\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n\u22120.011<\/td>\n0.010<\/td>\n<\/tr>\n
\u8abf\u6574\u6e08\u307f\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u5909\u5316\u306e\u5dee<\/td>\n<\/tr>\n
\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n\u22120.006<\/td>\n0.008<\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
b. \u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u305f\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\u3068\u30ed\u30b5\u30eb\u30bf\u30f3\u306e\u30a2\u30eb\u30d6\u30df\u30f3\u6392\u6cc4\u7387\u3068\u7cf8\u7403\u4f53\u6ffe\u904e\u7387\u306b\u5bfe\u3059\u308b5\u5e74\u9593\u306e\u8ffd\u8de1\u8abf\u67fb\u4e2d\u304a\u3088\u30735\u5e74\u76ee\u306e\u751f\u691c\u6642\u306e\u5f71\u97ff<\/strong><\/p>\n
\n<\/td>\n<\/tr>\n
<\/td>\n\u30d7\u30e9\u30bb\u30dc\uff08N=85\uff09<\/strong><\/td>\n\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\uff08N=86\uff09<\/strong><\/td>\n\u30ed\u30b5\u30eb\u30bf\u30f3\uff08N=85\uff09<\/strong><\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
\u30a2\u30eb\u30d6\u30df\u30f3\u6392\u6cc4\u7387\uff08\u03bcg\/\u5206\uff09<\/strong><\/td>\n<\/tr>\n
\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u5e73\u5747<\/td>\n6.4\u00b16<\/td>\n6.3\u00b15<\/td>\n6.5\u00b17<\/td>\n<\/tr>\n
\u5e73\u57475\u5e74\u4ee5\u4e0a\u306e\u8ffd\u8de1\u8abf\u67fb<\/td>\n6.5\u00b16<\/td>\n7.7\u00b116<\/td>\n10.6\u00b118<\/td>\n<\/tr>\n
\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n1.3<\/td>\n4.0<\/span><\/td>\n<\/tr>\n
5\u5e74\u3054\u3068\u306e\u751f\u691c\u8a2a\u554f\u6642\u306e\u5e73\u5747<\/td>\n5.3\u00b14<\/td>\n6.9\u00b18<\/td>\n14.0\u00b136<\/td>\n<\/tr>\n
\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n1.0<\/td>\n8.0<\/span><\/td>\n<\/tr>\n
\u7cf8\u7403\u4f53\u6ffe\u904e\u7387\uff08ml\/\u5206\/1.73m\u00a02<\/sup>\uff09<\/strong><\/td>\n<\/tr>\n
\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u5e73\u5747<\/td>\n126\u00b122<\/td>\n129\u00b120<\/td>\n131\u00b118<\/td>\n<\/tr>\n
\u5e73\u57475\u5e74\u4ee5\u4e0a\u306e\u8ffd\u8de1\u8abf\u67fb<\/td>\n125\u00b118<\/td>\n124\u00b118<\/td>\n125\u00b117<\/td>\n<\/tr>\n
\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n\u22122.6<\/td>\n\u22122.4<\/td>\n<\/tr>\n
5\u5e74\u3054\u3068\u306e\u751f\u691c\u8a2a\u554f\u6642\u306e\u5e73\u5747<\/td>\n120\u00b122<\/td>\n123\u00b120<\/td>\n121\u00b121<\/td>\n<\/tr>\n
\u30d7\u30e9\u30bb\u30dc\u3068\u306e<\/em>\u2003\u5e73\u5747\u5dee<\/td>\n0<\/td>\n0.4<\/td>\n1.5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u4e0a\u306e\u8868\u306eb\u306b\u793a\u3059\u3088\u3046\u306b\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u6392\u6cc4\u7387\u306f\u30ed\u30b5\u30eb\u30bf\u30f3\u7fa4\u3067\u306e\u307f\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u6709\u610f\u306b\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u30015\u5e74\u5e73\u5747\u30a2\u30eb\u30d6\u30df\u30f3\u6392\u6cc4\u7387\u306f\u30ed\u30b5\u30eb\u30bf\u30f3\u30674.0\u03bcg\/\u5206\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u30025\u5e74\u6642\u70b9\u3067\u306e\u30a2\u30eb\u30d6\u30df\u30f3\u6392\u6cc4\u7387\u306f\u3001\u30ed\u30b5\u30eb\u30bf\u30f3\u7fa4\u3067\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u3088\u308a8.0\u03bcg\/\u5206\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u7cf8\u7403\u4f53\u6ffe\u904e\u7387\u306f3\u7fa4\u3068\u3082\u540c\u69d8\u306b6.6\uff5e8.9 ml\/\u5206\u6e1b\u5c11\u3057\u307e\u3057\u305f\u304c\u3001\u4e00\u756a\u4f4e\u4e0b\u3057\u305f\u306e\u306f\u30ed\u30b5\u30eb\u30bf\u30f3\u7fa4\u3067\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306b\u793a\u3059\u3088\u3046\u306b\u3001\u5fae\u91cf\u30a2\u30eb\u30d6\u30df\u30f3\u5c3f\u306e5\u5e74\u9593\u7d2f\u7a4d\u767a\u751f\u7387\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u30676%\u3067\u3001\u30ed\u30b5\u30eb\u30bf\u30f3\u7fa4\u3067\u306f17%\u3067\u767a\u751f\u7387\u304c\u3088\u308a\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

ARB\u3067\u3042\u308b\u30ed\u30b5\u30eb\u30bf\u30f3\u306b\u306f\u3001\u814e\u4fdd\u8b77\u52b9\u679c\u306a\u3093\u3066\u5168\u304f\u306a\u3044\u3088\u3046\u306b\u3057\u304b\u898b\u3048\u307e\u305b\u3093\u3002<\/p>\n

\u4ed6\u306e\u7814\u7a76\u3082\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u3053\u3053<\/a>\u53c2\u7167\u3001\u56f3\u3082\u3053\u3053\u3088\u308a\uff09\u672b\u68a2\u81d3\u5668\u969c\u5bb3\u3092\u4f34\u3046\u304c\u30de\u30af\u30ed\u30a2\u30eb\u30d6\u30df\u30f3\u5c3f\u3084\u5fc3\u4e0d\u5168\u304c\u306a\u304f\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff08ACE\uff09\u963b\u5bb3\u5264\u306b\u8010\u3048\u3089\u308c\u306a\u3044\u65e2\u77e5\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u307e\u305f\u306f\u7cd6\u5c3f\u75c5\u306e5,927\u4eba\u304c\u5bfe\u8c61\u3067\u3059\u3002ARB\u306e\u30c6\u30eb\u30df\u30b5\u30eb\u30bf\u30f3\uff08\u5546\u54c1\u540d\u30df\u30ab\u30eb\u30c7\u30a3\u30b9\uff0980 mg\/\u65e5\u3001\u307e\u305f\u306f\u305d\u308c\u306b\u30de\u30c3\u30c1\u30f3\u30b0\u3057\u305f\u30d7\u30e9\u30bb\u30dc\u3068\u6a19\u6e96\u6cbb\u7642\u3092\u4f75\u7528\u3057\u305f\u7fa4\u306b\u5206\u3051\u3001\u5e73\u574756\u304b\u6708\u9593\u884c\u3044\u307e\u3057\u305f\u3002\u900f\u6790\u307e\u305f\u306f\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u306e\u500d\u5897\u3001\u63a8\u5b9a\u7cf8\u7403\u4f53\u6ffe\u904e\u7387 (GFR) \u306e\u5909\u5316\u3001\u304a\u3088\u3073\u30a2\u30eb\u30d6\u30df\u30f3\u5c3f\u306e\u5909\u5316\u306b\u3088\u308b\u8907\u5408\u7684\u306a\u814e\u81d3\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u900f\u6790\u307e\u305f\u306f\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024\u306e2\u500d\u5897\u52a0\u306e\u8907\u5408\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u767a\u751f\u7387\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u6709\u610f\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u30c6\u30eb\u30df\u30b5\u30eb\u30bf\u30f3\u7fa4\u306e\u65b9\u304c\u30d7\u30e9\u30bb\u30dc\u7fa4\u3088\u308a\u3082\u767a\u751f\u7387\u304c\u9ad8\u3044\u3088\u3046\u306b\u898b\u3048\u307e\u3059\u3002\u5b9f\u969b\u306b\u3001\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024\u306e2\u500d\u5897\u52a0\u3060\u3051\u3092\u898b\u308b\u3068\u3001\u30c6\u30eb\u30df\u30b5\u30eb\u30bf\u30f3\u30671.59\u500d\u6709\u610f\u306b\u767a\u751f\u7387\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

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\u300cThe role of angiotensin receptor blockers in CVD risk management\u300d<\/span><\/p>\n

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