{"id":30562,"date":"2025-05-07T12:23:17","date_gmt":"2025-05-07T03:23:17","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=30562"},"modified":"2025-05-07T12:23:17","modified_gmt":"2025-05-07T03:23:17","slug":"%e5%8f%8c%e6%a5%b5%e6%80%a7%e9%9a%9c%e5%ae%b3%e3%81%af%e7%b3%96%e8%b3%aa%e9%81%8e%e5%89%b0%e7%97%87%e5%80%99%e7%be%a4%e3%80%80%e3%81%9d%e3%81%ae1","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=30562","title":{"rendered":"\u53cc\u6975\u6027\u969c\u5bb3\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3000\u305d\u306e1"},"content":{"rendered":"<p>\u53cc\u6975\u6027\u969c\u5bb3\uff08\u4ee5\u524d\u306f\u8e81\u3046\u3064\u75c5\u3068\u3082\u8a00\u308f\u308c\u3066\u3044\u307e\u3057\u305f\uff09\u306f\u7cbe\u795e\u75be\u60a3\u306e\u4ee3\u8868\u7684\u306a\u75be\u60a3\u306e\u4e00\u3064\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u672c\u5f53\u306b\u7cbe\u795e\u75be\u60a3\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u591a\u304f\u306e\u7cbe\u795e\u75be\u60a3\u306f\u591a\u56e0\u5b50\u6027\u3067\u3042\u308b\u3068\u306f\u601d\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u5927\u304d\u306a\u539f\u56e0\u306e\u4e00\u3064\u306f\u4ee3\u8b1d\u969c\u5bb3\u3067\u3042\u308a\u3001\u7cbe\u795e\u75be\u60a3\u3068\u3044\u3046\u3088\u308a\u306f\u4ee3\u8b1d\u75be\u60a3\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u3082\u3063\u3068\u8a00\u3063\u3066\u3057\u307e\u3048\u3070\u3001\u7cbe\u795e\u75be\u60a3\u306e\u307b\u3068\u3093\u3069\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u3001\u53cc\u6975\u6027\u969c\u5bb3\u3082\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u975e\u5e38\u306b\u591a\u304f\u306e\u7814\u7a76\u304c\u3001\u8133\u5185\u306e\u7cd6\u4ee3\u8b1d\u969c\u5bb3\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u304c\u53cc\u6975\u6027\u969c\u5bb3\u306e\u6839\u5e95\u306b\u3042\u308b\u91cd\u5927\u306a\u554f\u984c\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3042\u308b\u7814\u7a76\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3068\u53cc\u6975\u6027\u969c\u5bb3\u306e\u8ee2\u5e30\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25323142\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\u3001\u56f3\u3082\u3053\u3053\u3088\u308a\uff09\u53cc\u6975\u6027\u969c\u5bb3\u306e\u6210\u4eba121\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u5024\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u3092\u6e2c\u5b9a\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u8a3a\u65ad\u3057\u307e\u3057\u305f\u3002I\u578b\u53cc\u6975\u6027\u969c\u5bb3\u3068\u8a3a\u65ad\u3055\u308c\u305f\u60a3\u8005\u306f69.9\uff05\u3092\u5360\u3081\u3001II\u578b\u53cc\u6975\u6027\u969c\u5bb3\u306f30.1\uff05\u3067\u3057\u305f\u3002\uff08I\u578b\u306f\u300c\u8e81\u72b6\u614b\u300d\u304c\u304a\u3053\u308b\u53cc\u6975\u6027\u969c\u5bb3\u3001II\u578b\u306f\u300c\u8efd\u8e81\u72b6\u614b\u300d\u3068\u300c\u3046\u3064\u72b6\u614b\u300d\u306e\u4e21\u65b9\u304c\u304a\u3053\u308b\u53cc\u6975\u6027\u969c\u5bb3\uff09\u5e73\u5747\u5e74\u9f62\u306f48.1\u6b73\u3001\u53cc\u6975\u6027\u969c\u5bb3\u306e\u8a3a\u65ad\u6642\u306e\u5e73\u5747\u5e74\u9f62\u306f22.6\u6b73\u30012\u578b\u7cd6\u5c3f\u75c5\u767a\u75c7\u6642\u306e\u5e73\u5747\u5e74\u9f62\u306f47.8\u6b73\u3067\u3057\u305f\u3002\u5e73\u5747BMI\u306f30.0\u3001\u7cd6\u5c3f\u75c5\u3068\u8a3a\u65ad\u3055\u308c\u3066\u3044\u306a\u3044\u5168\u53c2\u52a0\u8005\u306e\u5e73\u5747HOMA-IR\u306f2.02\u3001BMI\u3068HOMA-IR\u306e\u9593\u306b\u306f\u6b63\u306e\u76f8\u95a2\u95a2\u4fc2\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"30565\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=30565\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?fit=945%2C610&amp;ssl=1\" data-orig-size=\"945,610\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"\u53cc\u6975\u6027\u969c\u5bb3urn_cambridge.org_id_binary_20180606064932972-0056_S0007125000237410_S0007125000237410_fig1g\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?fit=300%2C194&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?fit=640%2C413&amp;ssl=1\" class=\"alignnone size-full wp-image-30565\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?resize=640%2C413\" alt=\"\" width=\"640\" height=\"413\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?w=945&amp;ssl=1 945w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?resize=300%2C194&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/e5fa7ff1450ae26f71352e1a4d6de978.jpeg?resize=768%2C496&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u75c5\u6c17\u306e\u7d4c\u904e\u304c\u6162\u6027\u306e\u7d4c\u904e\u3092\u305f\u3069\u3063\u305f\u5272\u5408\u3067\u3059\u3002\u6a2a\u8ef8\u306f\u5de6\u304b\u3089\u6b63\u5e38\u8840\u7cd6\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u30012\u578b\u7cd6\u5c3f\u75c5\u3067\u3059\u3002\u53cc\u6975\u6027\u969c\u5bb3\u304a\u3088\u30732\u578b\u7cd6\u5c3f\u75c5\u306e\u60a3\u8005\u306e50\uff05\u304a\u3088\u3073\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u60a3\u8005\u306e48.7\uff05\u304c\u6162\u6027\u7d4c\u904e\u3092\u305f\u3069\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001\u6b63\u5e38\u8840\u7cd6\u60a3\u8005\u3067\u306f27.3\uff05\u3067\u3057\u305f\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3001\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u3068\u6162\u6027\u7d4c\u904e\u3092\u305f\u3069\u308b\u53ef\u80fd\u6027\u304c\u7d043\u500d\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u307e\u305f\u306f2\u578b\u7cd6\u5c3f\u75c5\u306f\u3001BMI\u3092\u8003\u616e\u3057\u305f\u5f8c\u3067\u3082\u3001\u75c5\u72b6\u306e\u4e0d\u826f\u306a\u7d4c\u904e\u3092\u305f\u3069\u308b\u53ef\u80fd\u6027\u304c2.19\u500d\u3067\u3057\u305f\u3002<\/p>\n<p>2\u578b\u7cd6\u5c3f\u75c5\u307e\u305f\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3067\u306f\u6025\u6027\u4ea4\u4ee3\u578b\uff08rapid cycling\uff1a1\u5e74\u9593\u306b4\u56de\u4ee5\u4e0a\u8e81\u72b6\u614b\u3068\u3046\u3064\u72b6\u614b\u304c\u5207\u308a\u66ff\u308f\u308b\u53cc\u6975\u6027\u969c\u5bb3\u306e\u30bf\u30a4\u30d7\uff09\u306e\u53ef\u80fd\u6027\u30823.13\u500d\u3067\u3057\u305f\u3002<\/p>\n<p>BMI\u3092\u8abf\u6574\u3057\u305f\u5f8c\u3067\u3082\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u307e\u305f\u306f2\u578b\u7cd6\u5c3f\u75c5\u306f\u6025\u6027\u4ea4\u4ee3\u578b\u306e\u53ef\u80fd\u6027\u306f3.36\u500d\u3067\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"30564\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=30564\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?fit=937%2C688&amp;ssl=1\" data-orig-size=\"937,688\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"\u53cc\u6975\u6027\u969c\u5bb3urn_cambridge.org_id_binary_20180606064932972-0056_S0007125000237410_S0007125000237410_fig2g\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?fit=300%2C220&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?fit=640%2C470&amp;ssl=1\" class=\"alignnone size-full wp-image-30564\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?resize=640%2C470\" alt=\"\" width=\"640\" height=\"470\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?w=937&amp;ssl=1 937w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?resize=300%2C220&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/2b2690021f3c1f746abec1aed7c6c977.jpeg?resize=768%2C564&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u7cd6\u4ee3\u8b1d\u72b6\u614b\u3068\u30ea\u30c1\u30a6\u30e0\u7642\u6cd5\uff08\u53cc\u6975\u6027\u969c\u5bb3\u306e\u6cbb\u7642\u85ac\uff09\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u53cd\u5fdc\u3067\u3059\u3002\u6fc3\u3044\u9752\u304c\u5b8c\u5168\u5bdb\u89e3\u3001\u8584\u3044\u8272\u304c\u90e8\u5206\u5bdb\u89e3\u3001\u767d\u304c\u53cd\u5fdc\u306a\u3057\u3067\u3059\u3002\u6b63\u5e38\u8840\u7cd6\u306e\u60a3\u8005\u306e\u3046\u3061\u3001\u30ea\u30c1\u30a6\u30e0\u306b\u53cd\u5fdc\u3057\u306a\u304b\u3063\u305f\u306e\u306f\u308f\u305a\u304b3.2%\uff081\u4eba\uff09\u3067\u3042\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3067\u306f36.7%\u30012\u578b\u7cd6\u5c3f\u75c5\u3067\u306f36.8%\u304c\u53cd\u5fdc\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u6b63\u5e38\u8840\u7cd6\u60a3\u8005\u3067\u306f\u3001\u30ea\u30c1\u30a6\u30e0\u3067\u5bdb\u89e3\u306b\u9054\u3057\u305f\u5272\u5408\u304c54.8%\u3067\u3042\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u60a3\u8005\u3067\u306f23.3%\u30012\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u306f21.1%\u3057\u304b\u5bdb\u89e3\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u307e\u305f\u306f2\u578b\u7cd6\u5c3f\u75c5\u306f\u30ea\u30c1\u30a6\u30e0\u306b\u53cd\u5fdc\u6027\u3057\u306a\u3044\u53ef\u80fd\u6027\u306f8.40\u500d\u3067\u3057\u305f\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u307e\u305f\u306f2\u578b\u7cd6\u5c3f\u75c5\u306f\u3001BMI30\u672a\u6e80\u306e\u975e\u80a5\u6e80\u53c2\u52a0\u800542\u4eba\u306b\u304a\u3044\u3066\u3082\u3001\u30ea\u30c1\u30a6\u30e0\u975e\u53cd\u5fdc\u306e\u53ef\u80fd\u6027\u306f3.87\u500d\u3067\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"30563\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=30563\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?fit=923%2C656&amp;ssl=1\" data-orig-size=\"923,656\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"\u53cc\u6975\u6027\u969c\u5bb3urn_cambridge.org_id_binary_20180606064932972-0056_S0007125000237410_S0007125000237410_fig3g\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?fit=300%2C213&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?fit=640%2C455&amp;ssl=1\" class=\"alignnone size-full wp-image-30563\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?resize=640%2C455\" alt=\"\" width=\"640\" height=\"455\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?w=923&amp;ssl=1 923w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?resize=300%2C213&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/247a4389f5d927de25a8b02e44552aa4.jpeg?resize=768%2C546&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u30ea\u30c1\u30a6\u30e0\u3078\u306e\u53cd\u5fdc\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\uff08HOMA-IR\uff09\u3068\u306e\u95a2\u9023\u3067\u3059\u3002\u6a2a\u8ef8\u306f\u5de6\u304b\u3089\u5b8c\u5168\u5bdb\u89e3\u3001\u90e8\u5206\u7684\u306a\u5bdb\u89e3\u3001\u53cd\u5fdc\u306a\u3057\u3067\u3059\u3002\u660e\u3089\u304b\u306b\u53cd\u5fdc\u306a\u3057\u3067\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u975e\u5e38\u306b\u9ad8\u3044\u3067\u3059\u306d\u3002<\/p>\n<p>\u7cd6\u5c3f\u75c5\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u3082\u3061\u308d\u3093\u8133\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u4f34\u3046\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u7cd6\u5c3f\u75c5\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u5927\u304d\u304f\u53cc\u6975\u6027\u969c\u5bb3\u306e\u7d4c\u904e\u3084\u6cbb\u7642\u3078\u306e\u53cd\u5fdc\u306b\u5f71\u97ff\u3059\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u7cd6\u8cea\u5236\u9650\u3084\u30b1\u30c8\u30f3\u98df\u304c\u6709\u52b9\u306a\u306f\u305a\u3067\u3059\u3002\u5b9f\u969b\u306b\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=25891\" target=\"_blank\" rel=\"noopener\">\u53cc\u6975\u6027\u969c\u5bb3\u3068\u7d71\u5408\u5931\u8abf\u75c7\u306b\u304a\u3051\u308b\u7cd6\u8cea\u5236\u9650\u306e\u52b9\u679c<\/a>\u300d\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=19440\" target=\"_blank\" rel=\"noopener\">\u96e3\u6cbb\u6027\u7cbe\u795e\u75be\u60a3\u306e\u305f\u3081\u306e\u30b1\u30c8\u30f3\u98df\u306e\u9a5a\u304f\u3079\u304d\u52b9\u679c<\/a>\u300d\u306a\u3069\u306b\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u591a\u304f\u306e\u4eba\u304c\u30b1\u30c8\u30f3\u98df\uff08\u7cd6\u8cea\u5236\u9650\uff09\u3067\u75c7\u72b6\u304c\u6539\u5584\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4ed6\u306e\u7814\u7a76\u3067\u3082\u30b1\u30c8\u30f3\u98df\u306f\u69d8\u3005\u306a\u6539\u5584\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u307e\u3059\u3002\u53cc\u6975\u6027\u969c\u5bb3\u3092\u6301\u3064274\u4eba\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u98df\u4e8b\u4ecb\u5165\uff08\u30b1\u30c8\u30f3\u98df\u3001\u30aa\u30e1\u30ac 3 \u5f37\u5316\u3001\u30d9\u30b8\u30bf\u30ea\u30a2\u30f3\uff09\u306e\u6c17\u5206\u3078\u306e\u5f71\u97ff\u306e\u89b3\u5bdf\u5206\u6790\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002\u4e00\u5b9a\u671f\u9593\u306b\u308f\u305f\u308b\u6709\u610f\u306a\u6c17\u5206\u306e\u5b89\u5b9a\u307e\u305f\u306f\u75c7\u72b6\u306e\u7de9\u548c\u306b\u95a2\u3059\u308b\u5831\u544a\u306e\u53ef\u80fd\u6027\u306f\u3001\u30aa\u30e1\u30ac3\u5f37\u5316\u3084\u30d9\u30b8\u30bf\u30ea\u30a2\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30b1\u30c8\u30f3\u98df\u3067\u306f7.4\u500d\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u30b1\u30c8\u30f3\u98df\u306b\u95a2\u9023\u3059\u308b\u80af\u5b9a\u7684\u306a\u52b9\u679c\u3092\u5831\u544a\u3057\u305f85\u4eba\u4e2d\u300155\u4eba\uff0865\uff05\uff09\u3067\u6c17\u5206\u306e\u5b89\u5b9a\u6027\u304c\u6539\u5584\u300135\u4eba\uff0841.2 \uff05\uff09\u3067\u3046\u3064\u75c5\u30a8\u30d4\u30bd\u30fc\u30c9\u306e\u6e1b\u5c11\u300124\u4eba\uff0828.2\uff05\uff09\u3067\u601d\u8003\u3068\u4f1a\u8a71\u306e\u660e\u6670\u6027\u304c\u6539\u5584\u300122\u4eba\uff0825.9\uff05\uff09\u3067\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u5897\u52a0\u300117\u4eba\uff0820.0\uff05\uff09\u3067\u4e0d\u5b89\/\u30d1\u30cb\u30c3\u30af\u767a\u4f5c\u306e\u6e1b\u5c11\u300111\u4eba\uff0812.9\uff05\uff09\u3067\u8e81\u75c5\u30a8\u30d4\u30bd\u30fc\u30c9\u306e\u6e1b\u5c11\u30017\u4eba\uff088.2\uff05\uff09\u3067\u7761\u7720\u304c\u6539\u5584\u3001\u884c\u52d5\u5236\u5fa1\u306e\u6539\u5584\u306f7\u4eba\uff088.2%\uff09\u3001\u8a18\u61b6\u529b\u306e\u6539\u5584\u306f2\u4eba\uff082.4%\uff09\u3068\u69d8\u3005\u306a\u6709\u76ca\u306a\u5831\u544a\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u53cc\u6975\u6027\u969c\u5bb3\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u5927\u304d\u304f\u304b\u304b\u308f\u3063\u3066\u3044\u308b\u75be\u60a3\u3001\u3064\u307e\u308a\u4ee3\u8b1d\u75be\u60a3\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u7cbe\u795e\u79d1\u533b\u305f\u3061\u306f\u4ee3\u8b1d\u75be\u60a3\u3067\u3042\u308b\u3053\u3068\u3084\u3001\u98df\u4e8b\u3067\u75be\u60a3\u304c\u6539\u5584\u3057\u3066\u3057\u307e\u3063\u3066\u306f\u3001\u81ea\u5206\u305f\u3061\u306e\u7acb\u5834\u304c\u5371\u3046\u3044\u3068\u3067\u3082\u601d\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u300c<a href=\"https:\/\/www.secretariat.ne.jp\/jsmd\/iinkai\/katsudou\/data\/guideline_sokyoku2023.pdf\" target=\"_blank\" rel=\"noopener\">\u65e5\u672c\u3046\u3064\u75c5\u5b66\u4f1a\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 \u53cc\u6975\u75c72023<\/a>\u300d\u3067\u306f\u3001\u98df\u4e8b\u7642\u6cd5\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u6539\u5584\u6cbb\u7642\u306b\u3064\u3044\u3066\u306e\u8a00\u53ca\u306f\u5168\u304f\u306a\u304f\u3001\u85ac\u7269\u7642\u6cd5\u3070\u304b\u308a\u3067\u3001\u975e\u85ac\u7269\u7642\u6cd5\u3067\u306f\u975e\u5e38\u306b\u975e\u4eba\u9593\u7684\u306a\u6b8b\u9177\u306a\u6cbb\u7642\u6cd5\u306e\u96fb\u6c17\u3051\u3044\u308c\u3093\u7642\u6cd5\u3084\u4fb5\u8972\u7684\u306a\u6cbb\u7642\u6cd5\u306a\u3069\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002<\/p>\n<p>\u53cc\u6975\u6027\u969c\u5bb3\u3067\u3082\u76f4\u3055\u306a\u3044\u6cbb\u7642\u304c\u6a19\u6e96\u7684\u306a\u6cbb\u7642\u3068\u306a\u3063\u3066\u3057\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u7cbe\u795e\u75be\u60a3\u306e\u4e88\u9632\u3084\u6539\u5584\u306b\u306f\u7cd6\u8cea\u5236\u9650\u3067\u3059\u306d\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cKetosis and bipolar disorder: controlled analytic study of online reports\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u30b1\u30c8\u30fc\u30b7\u30b9\u3068\u53cc\u6975\u6027\u969c\u5bb3\uff1a\u30aa\u30f3\u30e9\u30a4\u30f3\u30ec\u30dd\u30fc\u30c8\u306e\u7ba1\u7406\u3055\u308c\u305f\u5206\u6790\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31530294\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u53cc\u6975\u6027\u969c\u5bb3\uff08\u4ee5\u524d\u306f\u8e81\u3046\u3064\u75c5\u3068\u3082\u8a00\u308f\u308c\u3066\u3044\u307e\u3057\u305f\uff09\u306f\u7cbe\u795e\u75be\u60a3\u306e\u4ee3\u8868\u7684\u306a\u75be\u60a3\u306e\u4e00\u3064\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u672c\u5f53\u306b\u7cbe\u795e\u75be\u60a3\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u591a\u304f\u306e\u7cbe\u795e\u75be\u60a3\u306f\u591a\u56e0\u5b50\u6027\u3067\u3042\u308b\u3068\u306f\u601d\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u5927\u304d\u306a\u539f\u56e0\u306e\u4e00\u3064\u306f\u4ee3\u8b1d\u969c\u5bb3\u3067\u3042\u308a\u3001\u7cbe\u795e\u75be\u60a3\u3068\u3044\u3046<\/p>\n","protected":false},"author":1,"featured_media":30570,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,150,111,15,154,10],"tags":[19,44,47,98],"class_list":["post-30562","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-diabetes","category-111","category-15","category-depression","category-10","tag-toushitsuseigen","tag-depression","tag-ir","tag-98","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/32033880_s.jpg?fit=640%2C427&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-7WW","jetpack-related-posts":[{"id":30622,"url":"https:\/\/promea2014.com\/blog\/?p=30622","url_meta":{"origin":30562,"position":0},"title":"\u53cc\u6975\u6027\u969c\u5bb3\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3000\u305d\u306e2","author":"Dr.Shimizu","date":"2025\u5e745\u670815\u65e5","format":false,"excerpt":"\u300c\u305d\u306e1\u300d\u306e\u7d9a\u304d\u3067\u3059\u3002 \u53cc\u6975\u6027\u969c\u5bb3\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u8d77\u3053\u308b\u30a4\u30f3\u30b9\u2026","rel":"","context":"\u7cd6\u5c3f\u75c5","block_context":{"text":"\u7cd6\u5c3f\u75c5","link":"https:\/\/promea2014.com\/blog\/?cat=150"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/25470024_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/25470024_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/05\/25470024_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":16483,"url":"https:\/\/promea2014.com\/blog\/?p=16483","url_meta":{"origin":30562,"position":1},"title":"\u4e0d\u5b89\u3068\u7cd6\u8cea\u904e\u5270\u6442\u53d6","author":"Dr.Shimizu","date":"2021\u5e748\u67082\u65e5","format":false,"excerpt":"\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u91cd\u75c7\u5316\u3068\u57fa\u790e\u75be\u60a3\u300d\u3067\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u91cd\u75c7\u5316\u306e\u30ea\u30b9\u30af\u3068\u57fa\u790e\u75be\u60a3\u306e\u95a2\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/07\/22014834_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/07\/22014834_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2021\/07\/22014834_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":28320,"url":"https:\/\/promea2014.com\/blog\/?p=28320","url_meta":{"origin":30562,"position":2},"title":"\u3080\u305a\u3080\u305a\u811a\u75c7\u5019\u7fa4\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3000\u305d\u306e1","author":"Dr.Shimizu","date":"2024\u5e7412\u670823\u65e5","format":false,"excerpt":"\u79c1\u306f\u3080\u305a\u3080\u305a\u811a\u75c7\u5019\u7fa4\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002 \u307e\u305a\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u4ee3\u8868\u75be\u60a3\u30012\u578b\u7cd6\u5c3f\u75c5\u3068\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/11\/30854160_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/11\/30854160_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/11\/30854160_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":25891,"url":"https:\/\/promea2014.com\/blog\/?p=25891","url_meta":{"origin":30562,"position":3},"title":"\u53cc\u6975\u6027\u969c\u5bb3\u3068\u7d71\u5408\u5931\u8abf\u75c7\u306b\u304a\u3051\u308b\u7cd6\u8cea\u5236\u9650\u306e\u52b9\u679c","author":"Dr.Shimizu","date":"2024\u5e744\u670825\u65e5","format":false,"excerpt":"\u7cbe\u795e\u75be\u60a3\u306e\u591a\u304f\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u7cbe\u795e\u7684\u5065\u5eb7\u3068\u4ee3\u8b1d\u7684\u5065\u5eb7\u306f\u3064\u306a\u304c\u3063\u3066\u3044\u307e\u3059\u3002\u4ee3\u8b1d\u3092\u6539\u5584\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/04\/29576391_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/04\/29576391_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2024\/04\/29576391_s.jpg?fit=640%2C426&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":33949,"url":"https:\/\/promea2014.com\/blog\/?p=33949","url_meta":{"origin":30562,"position":4},"title":"\u7cd6\u8cea\u5236\u9650\u306f\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306b\u3082\u826f\u3044\u5f71\u97ff\u3092\u53ca\u307c\u3059","author":"Dr.Shimizu","date":"2026\u5e744\u670822\u65e5","format":false,"excerpt":"\u7cbe\u795e\u79d1\u3084\u5fc3\u7642\u5185\u79d1\u3067\u3001\u6700\u521d\u306b\u98df\u4e8b\u6539\u5584\u3092\u3059\u308b\u3053\u3068\u306f\u307b\u3068\u3093\u3069\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u305d\u3057\u3066\u3001\u3069\u3093\u3069\u3093\u85ac\u304c\u5897\u3048\u3066\u3001\u629c\u3051\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/04\/33890512_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/04\/33890512_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/04\/33890512_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":19440,"url":"https:\/\/promea2014.com\/blog\/?p=19440","url_meta":{"origin":30562,"position":5},"title":"\u96e3\u6cbb\u6027\u7cbe\u795e\u75be\u60a3\u306e\u305f\u3081\u306e\u30b1\u30c8\u30f3\u98df\u306e\u9a5a\u304f\u3079\u304d\u52b9\u679c","author":"Dr.Shimizu","date":"2022\u5e747\u670811\u65e5","format":false,"excerpt":"\u6050\u3089\u304f\u4e16\u754c\u3067\u5104\u5358\u4f4d\u306e\u4eba\u304c\u3046\u3064\u75c5\u306a\u3069\u7cbe\u795e\u75be\u60a3\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u69d8\u3005\u306a\u6cbb\u7642\u85ac\u304c\u3042\u308a\u306a\u304c\u3089\u3001\u6cbb\u7642\u62b5\u6297\u6027\u306e\u4eba\u3082\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/07\/22945667_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/07\/22945667_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2022\/07\/22945667_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/30562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=30562"}],"version-history":[{"count":3,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/30562\/revisions"}],"predecessor-version":[{"id":30571,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/30562\/revisions\/30571"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/media\/30570"}],"wp:attachment":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=30562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=30562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=30562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}