{"id":31855,"date":"2025-08-14T08:45:22","date_gmt":"2025-08-13T23:45:22","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=31855"},"modified":"2025-08-14T09:46:02","modified_gmt":"2025-08-14T00:46:02","slug":"%e5%bf%83%e7%ad%8b%e7%82%8e%e3%81%8a%e3%82%88%e3%81%b3%e5%bf%83%e8%86%9c%e7%82%8e%e3%81%ae%e6%9c%89%e5%ae%b3%e4%ba%8b%e8%b1%a1%e3%81%ab%e9%96%a2%e9%80%a3%e3%81%99%e3%82%8b%e8%96%ac%e5%89%a4%e3%83%88","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=31855","title":{"rendered":"\u5fc3\u7b4b\u708e\u304a\u3088\u3073\u5fc3\u819c\u708e\u306e\u6709\u5bb3\u4e8b\u8c61\u306b\u95a2\u9023\u3059\u308b\u85ac\u5264\u30c8\u30c3\u30d710"},"content":{"rendered":"

\u5fc3\u7b4b\u708e\u3068\u5fc3\u819c\u708e\u306f\u6bd4\u8f03\u7684\u307e\u308c\u3067\u3059\u304c\u3001\u5065\u5eb7\u3078\u306e\u5f71\u97ff\u306f\u6df1\u523b\u3067\u3059\u3002\u8efd\u5ea6\u306e\u75c7\u72b6\u304b\u3089\u3001\u5fc3\u4e0d\u5168\u3001\u4e0d\u6574\u8108\u3001\u3055\u3089\u306b\u306f\u7a81\u7136\u306e\u5fc3\u81d3\u6b7b\u306a\u3069\u306e\u91cd\u7be4\u306a\u5408\u4f75\u75c7\u307e\u3067\u591a\u5c90\u306b\u308f\u305f\u308a\u307e\u3059\u3002\u8efd\u5ea6\u306e\u75c7\u72b6\u3060\u3068\u601d\u3063\u3066\u3082\u3001\u7622\u75d5\u3092\u6b8b\u3057\u3001\u305d\u3053\u304b\u3089\u4e0d\u6574\u8108\u304c\u767a\u751f\u3057\u7a81\u7136\u6b7b\u3068\u3044\u3046\u30d1\u30bf\u30fc\u30f3\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u7279\u5b9a\u306e\u85ac\u5264\u304c\u5fc3\u7b4b\u708e\u304a\u3088\u3073\u5fc3\u819c\u708e\u306e\u8a98\u56e0\u3068\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u30011968\u5e74\u304b\u30892024\u5e74\u306e\u9593\u306e\u4e16\u754c\u7684\u306a\u533b\u85ac\u54c1\u5b89\u5168\u6027\u76e3\u8996\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u5fc3\u7b4b\u708e\u304c8,293,350\u4ef6\u3001\u5fc3\u819c\u708e\u304c8,631,131\u4ef6\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u00a0<\/span><\/td>\n\u00a0<\/span><\/td>\n\u5fc3\u7b4b\u708e\u3001\u6570\uff08\uff05\uff09<\/span><\/td>\n\u5fc3\u819c\u708e\u3001\u6570\uff08\uff05\uff09<\/span><\/td>\n<\/tr>\n
\u5831\u544a\u5e74<\/span><\/td>\n1968\uff5e1979\u5e74<\/span><\/td>\n0 (0)<\/span><\/td>\n5 (0.02)<\/span><\/td>\n<\/tr>\n
<\/td>\n1980\uff5e1989\u5e74<\/span><\/td>\n3 (0.01)<\/span><\/td>\n24 (0.10)<\/span><\/td>\n<\/tr>\n
<\/td>\n1990\uff5e1999\u5e74<\/span><\/td>\n88 (0.25)<\/span><\/td>\n99 (0.40)<\/span><\/td>\n<\/tr>\n
<\/td>\n2000\uff5e2009\u5e74<\/span><\/td>\n705 (2.01)<\/span><\/td>\n340 (1.36)<\/span><\/td>\n<\/tr>\n
<\/td>\n2010\uff5e2019\u5e74<\/span><\/td>\n3,651 (10.43)<\/span><\/td>\n1,933 (7.74)<\/span><\/td>\n<\/tr>\n
<\/td>\n2020\uff5e2024\u5e74<\/span><\/td>\n30,570 (87.3)<\/span><\/td>\n22,558 (90.38)<\/span><\/td>\n<\/tr>\n
\u6027\u5225<\/span><\/td>\n\u7537<\/span><\/td>\n23,407 (66.84)<\/span><\/td>\n13,324 (53.38)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u5973\u6027<\/span><\/td>\n11,118 (31.75)<\/span><\/td>\n11,433 (45.81)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u672a\u77e5<\/span><\/td>\n492 (1.41)<\/span><\/td>\n202 (0.81)<\/span><\/td>\n<\/tr>\n
\u5e74\u9f62\u3001\u5e74<\/span><\/td>\n0\uff5e17\u6b73<\/span><\/td>\n2921 (8.34)<\/span><\/td>\n1,058 (4.24)<\/span><\/td>\n<\/tr>\n
<\/td>\n18\uff5e44\u6b73<\/span><\/td>\n15,526 (44.34)<\/span><\/td>\n9,954 (39.88)<\/span><\/td>\n<\/tr>\n
<\/td>\n45\uff5e64\u6b73<\/span><\/td>\n5,885 (16.81)<\/span><\/td>\n5,797 (23.23)<\/span><\/td>\n<\/tr>\n
<\/td>\n65\uff5e74\u6b73<\/span><\/td>\n1,642 (4.69)<\/span><\/td>\n1,357 (5.44)<\/span><\/td>\n<\/tr>\n
<\/td>\n75\u6b73\u4ee5\u4e0a<\/span><\/td>\n1,018 (2.91)<\/span><\/td>\n782 (3.13)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u672a\u77e5<\/span><\/td>\n8,025 (22.92)<\/span><\/td>\n6,011 (24.08)<\/span><\/td>\n<\/tr>\n
\u767a\u75c7\u307e\u3067\u306e\u6642\u9593\u3001\u65e5\u6570<\/span><\/td>\n\u4e2d\u592e\u65e5\u6570\uff08IQR\uff09<\/span><\/td>\n1\uff081\u20131\uff09<\/span><\/td>\n1\uff081\u20131\uff09<\/span><\/td>\n<\/tr>\n
<\/td>\n\u5e73\u5747\uff08SD\uff09<\/span><\/td>\n9.52 (62.68)<\/span><\/td>\n6.46 (44.78)<\/span><\/td>\n<\/tr>\n
\u7d50\u679c<\/span><\/td>\n\u56de\u5fa9<\/span><\/td>\n10,864 (31.02)<\/span><\/td>\n8,216 (32.92)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u56de\u5fa9\u3057\u3066\u3044\u306a\u3044<\/span><\/td>\n4,703 (13.43)<\/span><\/td>\n4,697 (18.82)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u81f4\u547d\u7684<\/span><\/td>\n741 (2.11)<\/span><\/td>\n119 (0.48)<\/span><\/td>\n<\/tr>\n
<\/td>\n\u672a\u77e5<\/span><\/td>\n18,709 (53.43)<\/span><\/td>\n11,927 (47.79)<\/span><\/td>\n<\/tr>\n
\u5358\u4e00\u306e\u85ac\u7269\u304c\u7591\u308f\u308c\u308b<\/span><\/td>\n<\/td>\n35,017 (100.00)<\/span><\/td>\n24,959 (100.00)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u30012020\uff5e2024\u5e74\u304c\u7a81\u51fa\u3057\u3066\u591a\u3044\u3067\u3059\u306d\u3002\u306a\u305c\u304b\u308f\u304b\u308a\u307e\u3059\u306d\u3002\u6df1\u523b\u306a\u306e\u306f\u30010\uff5e17\u6b73\u300118\uff5e44\u6b73\u3068\u3044\u3046\u3001\u3053\u308c\u304b\u3089\u5c06\u6765\u304c\u3042\u308b\u4eba\u305f\u3061\u304c\u5fc3\u7b4b\u708e\u3084\u5fc3\u819c\u708e\u306b\u306a\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u56de\u5fa9\u3057\u3066\u3044\u306a\u3044\u4eba\u305f\u3061\u3082\u591a\u3044\u3067\u3059\u3002<\/span><\/p>\n

\"\"<\/a><\/p>\n

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\u4e0b\u306e\u56f3\u306f\u85ac\u5264\u95a2\u9023\u5fc3\u7b4b\u708e\u306e\u6709\u5bb3\u4e8b\u8c61\u306eIC 025 (A)\u304a\u3088\u3073 ROR\u3067\u3059\u3002\u30b7\u30b0\u30ca\u30eb\u6307\u6a19\u3068\u3057\u3066\u306fInformation Component\uff08IC\uff09\u3092\u7b97\u51fa\u3057\u3001IC\u306e95%\u4fe1\u983c\u533a\u9593\u306e\u4e0b\u9650\u5024\uff08IC025\uff09\u304c0\u3092\u8d85\u3048\u308b\u5834\u5408\u3092\u30b7\u30b0\u30ca\u30eb\u304c\u691c\u51fa\u3055\u308c\u305f\u3068\u307f\u306a\u3057\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0b\u306e\u56f3\u306f\u85ac\u5264\u95a2\u9023\u5fc3\u819c\u708e\u306e\u6709\u5bb3\u4e8b\u8c61\u306eIC 025 (A)\u304a\u3088\u3073 ROR\u3067\u3059\u3002<\/p>\n

\"\"<\/a>\u5929\u7136\u75d8\u30ef\u30af\u30c1\u30f3\u306f\u5fc3\u7b4b\u708e\u306eROR103.62\u3001\u5fc3\u819c\u708e\u306eROR111.93\u3068\u4e21\u65b9\u3067\u6700\u3082\u9ad8\u3044\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u65b0\u578b\u30b3\u30ed\u30camRNA\u30ef\u30af\u30c1\u30f3\u306f\u4e21\u65b9\u306e\u5831\u544a\u6570\u306b\u304a\u3044\u3066\u6700\u3082\u591a\u304f\u306e\u5831\u544a\u6570\u3092\u793a\u3057\u305f\u3082\u306e\u306e\u3001\u5fc3\u7b4b\u708eROR38.3\u3068\u5fc3\u819c\u708eROR55.95\u3068\u5929\u7136\u75d8\u3088\u308a\u306f\u4f4e\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u6700\u3082\u9ad8\u3044IC\u5024\u306f\u5929\u7136\u75d8\u30ef\u30af\u30c1\u30f3\u3067\u89b3\u5bdf\u3055\u308c\u3001\u5fc3\u7b4b\u708e\u306eIC\u306f6.43\u3001\u5fc3\u819c\u708e\u306eIC\u306f6.50\u3067\u3057\u305f\u3002<\/p>\n

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\u300cTop 10 drugs most frequently associated with adverse events of myocarditis and pericarditis\u300d<\/span><\/p>\n

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