{"id":31878,"date":"2025-09-12T08:25:05","date_gmt":"2025-09-11T23:25:05","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=31878"},"modified":"2025-09-12T08:25:05","modified_gmt":"2025-09-11T23:25:05","slug":"sglt-2%e9%98%bb%e5%ae%b3%e5%89%a4%e3%81%ab%e3%82%88%e3%82%8b%e3%83%aa%e3%82%a2%e3%83%ab%e3%83%af%e3%83%bc%e3%83%ab%e3%83%89%e3%81%ae%e5%89%af%e4%bd%9c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=31878","title":{"rendered":"SGLT-2\u963b\u5bb3\u5264\u306b\u3088\u308b\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u306e\u526f\u4f5c\u7528"},"content":{"rendered":"

\u533b\u7642\u306e\u4e2d\u3067\u306f\u3001SGLT-2\u963b\u5bb3\u5264\u306f\u7d20\u6674\u3089\u3057\u3044\u85ac\u306e\u3088\u3046\u306b\u3082\u3066\u306f\u3084\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306e\u85ac\u3068\u3057\u3066\u3060\u3051\u3067\u306a\u304f\u3001\u5fc3\u4e0d\u5168\u3084\u6162\u6027\u814e\u81d3\u75c5\u306e\u85ac\u3068\u3057\u3066\u3082\u9069\u5fdc\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u304b\u3089\u304f\u308a\u306f\u5225\u3068\u3057\u3066\u3001\u3053\u306eSGLT-2\u963b\u5bb3\u5264\u306f\u3084\u3063\u3071\u308a\u85ac\u3067\u3042\u308a\u3001\u69d8\u3005\u306a\u526f\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30a2\u30e1\u30ea\u30ab\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u306e\u6709\u5bb3\u4e8b\u8c61\u5831\u544a\u30b7\u30b9\u30c6\u30e0\uff08FAERS\uff09\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3066\u3001SGLT-2\u963b\u5bb3\u5264\u306e\u4e00\u3064\u3067\u3042\u308b\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff08\u5546\u54c1\u540d\u30b8\u30e3\u30c7\u30a3\u30a2\u30f3\u30b9\uff09\u306e\u6709\u5bb3\u4e8b\u8c61\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u3044\u304f\u3064\u3082\u306e\u65b9\u6cd5\u3092\u7528\u3044\u3066\u3001\u6709\u5bb3\u4e8b\u8c61\u306e\u5371\u967a\u30b7\u30b0\u30ca\u30eb\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5371\u967a\u6027\u306e\u30b7\u30b0\u30ca\u30eb\u306e\u57fa\u6e96\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n\n\n\n\n\n\n\n\n
\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0<\/th>\n\u57fa\u6e96<\/th>\n<\/tr>\n<\/thead>\n
ROR<\/td>\nn<\/em>\u2009\u2265\u20093<\/p>\n

95% CI \u306e\u4e0b\u9650 <\/span>>\u20091<\/td>\n<\/tr>\n

PRR<\/td>\nn<\/em>\u2009\u2265\u20093<\/p>\n

PRR\u2009\u2265\u20092<\/p>\n

\u03c72<\/sup>\u2009\u2265\u20094<\/td>\n<\/tr>\n

BCPNN<\/td>\nIC025\u2009>\u20090<\/td>\n<\/tr>\n
MGPS<\/td>\nEBGM05\u2009>\u20092<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
<\/div>\n
\n

FAERS\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306e\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306e\u5831\u544a\u306e\u30b7\u30b0\u30ca\u30eb\u5f37\u5ea6<\/span><\/p>\n<\/div>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/th>\n<\/th>\n\u4e8b\u4f8b<\/span><\/th>\nROR<\/span>
\n\uff0895%\u4fe1\u983c\u533a\u9593\uff09<\/span><\/th>\n		PRR<\/span><\/th>\n\u03c7\u00a0<\/span>2<\/span><\/sup><\/th>\nIC<\/span>
\n\uff08IC025\uff09<\/span><\/th>\n		EBGM<\/span>
\n\uff08EBGM05\uff09<\/span><\/th>\n<\/tr>\n<\/thead>\n
\u5916\u79d1\u624b\u8853\u304a\u3088\u3073\u533b\u7642\u51e6\u7f6e<\/span><\/td>\n\u8db3\u6307\u5207\u65ad<\/span><\/td>\n94<\/span><\/td>\n24.30 (19.80\u201329.81)<\/span><\/td>\n24.25<\/span><\/td>\n2051.29<\/span><\/td>\n23.76 (20.02)<\/span><\/td>\n4.57 (2.90)<\/span><\/td>\n<\/tr>\n
\u5fc3\u81d3\u624b\u8853<\/span><\/td>\n43<\/span><\/td>\n7.65 (5.67\u201310.33)<\/span><\/td>\n7.65<\/span><\/td>\n246.86<\/span><\/td>\n7.60 (5.92)<\/span><\/td>\n2.93 (1.26)<\/span><\/td>\n<\/tr>\n
\u751f\u6b96\u5668\u7cfb\u304a\u3088\u3073\u4e73\u623f\u75be\u60a3<\/span><\/td>\n\u4e80\u982d\u5305\u76ae\u708e<\/span><\/td>\n62<\/span><\/td>\n113.31 (87.26\u2013147.13)<\/span><\/td>\n113.15<\/span><\/td>\n6267.14<\/span><\/td>\n102.98 (82.77)<\/span><\/td>\n6.69 (5.02)<\/span><\/td>\n<\/tr>\n
\u6027\u5668\u63bb\u75d2\u75c7<\/span><\/td>\n86<\/span><\/td>\n57.40 (46.21\u201371.30)<\/span><\/td>\n57.29<\/span><\/td>\n4528.05<\/span><\/td>\n54.59 (45.53)<\/span><\/td>\n5.77 (4.10)<\/span><\/td>\n<\/tr>\n
\u5916\u9670\u81a3\u305d\u3046\u75d2\u75c7<\/span><\/td>\n126<\/span><\/td>\n36.09 (30.22\u201343.11)<\/span><\/td>\n35.99<\/span><\/td>\n4154.94<\/span><\/td>\n34.92 (30.09)<\/span><\/td>\n5.13 (3.46)<\/span><\/td>\n<\/tr>\n
\u814e\u81d3\u304a\u3088\u3073\u5c3f\u8def\u75be\u60a3<\/span><\/td>\n\u30b1\u30c8\u30f3\u5c3f\u75c7<\/span><\/td>\n89<\/span><\/td>\n167.60 (134.14\u2013209.42)<\/span><\/td>\n167.26<\/span><\/td>\n12820.10<\/span><\/td>\n145.91 (121.10)<\/span><\/td>\n7.19 (5.52)<\/span><\/td>\n<\/tr>\n
\u983b\u5c3f<\/span><\/td>\n712<\/span><\/td>\n24.64 (22.87\u201326.56)<\/span><\/td>\n24.26<\/span><\/td>\n15555.27<\/span><\/td>\n23.77 (22.33)<\/span><\/td>\n4.57 (2.91)<\/span><\/td>\n<\/tr>\n
\u591a\u5c3f<\/span><\/td>\n107<\/span><\/td>\n18.34 (15.15\u201322.20)<\/span><\/td>\n18.29<\/span><\/td>\n1721.88<\/span><\/td>\n18.02 (15.36)<\/span><\/td>\n4.17 (2.51)<\/span><\/td>\n<\/tr>\n
\u5c3f\u306e\u81ed\u3044\u304c\u7570\u5e38<\/span><\/td>\n63<\/span><\/td>\n14.52 (11.32\u201318.62)<\/span><\/td>\n14.50<\/span><\/td>\n781.93<\/span><\/td>\n14.33 (11.64)<\/span><\/td>\n3.84 (2.17)<\/span><\/td>\n<\/tr>\n
\u6392\u5c3f\u5207\u8feb\u611f<\/span><\/td>\n86<\/span><\/td>\n10.79 (8.72\u201313.34)<\/span><\/td>\n10.77<\/span><\/td>\n754.90<\/span><\/td>\n10.67 (8.94)<\/span><\/td>\n3.42 (1.75)<\/span><\/td>\n<\/tr>\n
\u814e\u81d3\u306e\u75db\u307f<\/span><\/td>\n47<\/span><\/td>\n6.21 (4.66\u20138.27)<\/span><\/td>\n6.20<\/span><\/td>\n204.07<\/span><\/td>\n6.18 (4.86)<\/span><\/td>\n2.63 (0.96)<\/span><\/td>\n<\/tr>\n
\u591c\u9593\u983b\u5c3f<\/span><\/td>\n44<\/span><\/td>\n5.36 (3.98\u20137.20)<\/span><\/td>\n5.35<\/span><\/td>\n154.96<\/span><\/td>\n5.33 (4.16)<\/span><\/td>\n2.41 (0.75)<\/span><\/td>\n<\/tr>\n
\u795e\u7d4c\u7cfb\u969c\u5bb3<\/span><\/td>\n\u610f\u8b58\u306e\u5909\u6027\u72b6\u614b<\/span><\/td>\n78<\/span><\/td>\n5.42 (4.33\u20136.77)<\/span><\/td>\n5.41<\/span><\/td>\n278.96<\/span><\/td>\n5.39 (4.47)<\/span><\/td>\n2.43 (0.76)<\/span><\/td>\n<\/tr>\n
\u8133\u6897\u585e<\/span><\/td>\n79<\/span><\/td>\n4.36 (3.50\u20135.44)<\/span><\/td>\n4.36<\/span><\/td>\n203.72<\/span><\/td>\n4.35 (3.61)<\/span><\/td>\n2.12 (0.45)<\/span><\/td>\n<\/tr>\n
\u4ee3\u8b1d\u304a\u3088\u3073\u6804\u990a\u969c\u5bb3<\/span><\/td>\n\u6b63\u5e38\u8840\u7cd6\u7cd6\u5c3f\u75c5\u6027\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/span><\/td>\n909<\/span><\/td>\n744.18 (684.33\u2013809.26)<\/span><\/td>\n728.70<\/span><\/td>\n402327.22<\/span><\/td>\n444.19 (414.10)<\/span><\/td>\n8.80 (7.13)<\/span><\/td>\n<\/tr>\n
\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/span><\/td>\n1006<\/span><\/td>\n228.77 (213.67\u2013244.93)<\/span><\/td>\n223.52<\/span><\/td>\n186211.02<\/span><\/td>\n186.91 (176.53)<\/span><\/td>\n7.55 (5.88)<\/span><\/td>\n<\/tr>\n
\u7cd6\u5c3f\u75c5\u6027\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/span><\/td>\n2747<\/span><\/td>\n197.74 (189.71\u2013206.12)<\/span><\/td>\n185.35<\/span><\/td>\n433157.89<\/span><\/td>\n159.48 (154.04)<\/span><\/td>\n7.32 (5.65)<\/span><\/td>\n<\/tr>\n
\u7570\u5e38\u306a\u4f53\u91cd\u6e1b\u5c11<\/span><\/td>\n156<\/span><\/td>\n33.39 (28.47\u201339.16)<\/span><\/td>\n33.27<\/span><\/td>\n4744.79<\/span><\/td>\n32.35 (28.31)<\/span><\/td>\n5.02 (3.35)<\/span><\/td>\n<\/tr>\n
\u591a\u98f2\u75c7<\/span><\/td>\n72<\/span><\/td>\n25.00 (19.79\u201331.59)<\/span><\/td>\n24.96<\/span><\/td>\n1620.71<\/span><\/td>\n24.45 (20.11)<\/span><\/td>\n4.61 (2.94)<\/span><\/td>\n<\/tr>\n
\u4ee3\u8b1d\u6027\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9<\/span><\/td>\n238<\/span><\/td>\n11.09 (9.75\u201312.60)<\/span><\/td>\n11.03<\/span><\/td>\n2151.04<\/span><\/td>\n10.93 (9.82)<\/span><\/td>\n3.45 (1.78)<\/span><\/td>\n<\/tr>\n
\u8131\u6c34<\/span><\/td>\n529<\/span><\/td>\n5.49 (5.04\u20135.98)<\/span><\/td>\n5.44<\/span><\/td>\n1910.00<\/span><\/td>\n5.41 (5.04)<\/span><\/td>\n2.44 (0.77)<\/span><\/td>\n<\/tr>\n
\u691c\u67fb<\/span><\/td>\n\u5c3f\u4e2d\u30b1\u30c8\u30f3\u4f53<\/span><\/td>\n45<\/span><\/td>\n506.27 (356.26\u2013719.45)<\/span><\/td>\n505.75<\/span><\/td>\n15682.00<\/span><\/td>\n350.18 (260.97)<\/span><\/td>\n8.45 (6.77)<\/span><\/td>\n<\/tr>\n
\u8840\u4e2d\u30b1\u30c8\u30f3\u4f53\u5897\u52a0<\/span><\/td>\n126<\/span><\/td>\n313.19 (257.08\u2013381.53)<\/span><\/td>\n312.29<\/span><\/td>\n30661.58<\/span><\/td>\n245.12 (207.80)<\/span><\/td>\n7.94 (6.27)<\/span><\/td>\n<\/tr>\n
\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u306e\u6e1b\u5c11<\/span><\/td>\n63<\/span><\/td>\n65.64 (50.91\u201384.64)<\/span><\/td>\n65.55<\/span><\/td>\n3785.99<\/span><\/td>\n62.02 (50.14)<\/span><\/td>\n5.95 (4.29)<\/span><\/td>\n<\/tr>\n
\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u5897\u52a0<\/span><\/td>\n379<\/span><\/td>\n22.64 (20.45\u201325.08)<\/span><\/td>\n22.46<\/span><\/td>\n7622.05<\/span><\/td>\n22.04 (20.24)<\/span><\/td>\n4.46 (2.80)<\/span><\/td>\n<\/tr>\n
\u7cf8\u7403\u4f53\u6ffe\u904e\u7387\u306e\u4f4e\u4e0b<\/span><\/td>\n100<\/span><\/td>\n13.64 (11.20\u201316.62)<\/span><\/td>\n13.61<\/span><\/td>\n1154.77<\/span><\/td>\n13.46 (11.41)<\/span><\/td>\n3.75 (2.08)<\/span><\/td>\n<\/tr>\n
\u8840\u7cd6\u5024\u306e\u4e0a\u6607<\/span><\/td>\n974<\/span><\/td>\n7.07 (6.64\u20137.54)<\/span><\/td>\n6.94<\/span><\/td>\n4935.98<\/span><\/td>\n6.90 (6.54)<\/span><\/td>\n2.79 (1.12)<\/span><\/td>\n<\/tr>\n
\u4f53\u91cd\u6e1b\u5c11<\/span><\/td>\n939<\/span><\/td>\n4.76 (4.46\u20135.07)<\/span><\/td>\n4.67<\/span><\/td>\n2713.72<\/span><\/td>\n4.66 (4.41)<\/span><\/td>\n2.22 (0.55)<\/span><\/td>\n<\/tr>\n
\u611f\u67d3\u75c7\u3068\u5bc4\u751f\u866b\u611f\u67d3<\/span><\/td>\n\u30d5\u30eb\u30cb\u30a8\u58ca\u75bd<\/span><\/td>\n525<\/span><\/td>\n610.52 (548.96\u2013678.98)<\/span><\/td>\n603.18<\/span><\/td>\n206109.86<\/span><\/td>\n394.23 (360.69)<\/span><\/td>\n8.62 (6.96)<\/span><\/td>\n<\/tr>\n
\u6027\u5668\u771f\u83cc\u611f\u67d3\u75c7<\/span><\/td>\n53<\/span><\/td>\n95.31 (72.00\u2013126.16)<\/span><\/td>\n95.19<\/span><\/td>\n4557.66<\/span><\/td>\n87.91 (69.52)<\/span><\/td>\n6.46 (4.79)<\/span><\/td>\n<\/tr>\n
\u771f\u83cc\u611f\u67d3\u75c7<\/span><\/td>\n1268<\/span><\/td>\n57.87 (54.65\u201361.27)<\/span><\/td>\n56.22<\/span><\/td>\n65558.80<\/span><\/td>\n53.61 (51.11)<\/span><\/td>\n5.74 (4.08)<\/span><\/td>\n<\/tr>\n
\u58ca\u6b7b\u6027\u7b4b\u819c\u708e<\/span><\/td>\n126<\/span><\/td>\n55.70 (46.57\u201366.63)<\/span><\/td>\n55.54<\/span><\/td>\n6434.38<\/span><\/td>\n53.00 (45.62)<\/span><\/td>\n5.73 (4.06)<\/span><\/td>\n<\/tr>\n
\u5916\u9670\u81a3\u771f\u83cc\u611f\u67d3\u75c7<\/span><\/td>\n95<\/span><\/td>\n30.56 (24.92\u201337.48)<\/span><\/td>\n30.50<\/span><\/td>\n2639.62<\/span><\/td>\n29.73 (25.06)<\/span><\/td>\n4.89 (3.23)<\/span><\/td>\n<\/tr>\n
\u5c3f\u8def\u6557\u8840\u75c7<\/span><\/td>\n106<\/span><\/td>\n16.31 (13.47\u201319.77)<\/span><\/td>\n16.28<\/span><\/td>\n1498.68<\/span><\/td>\n16.06 (13.68)<\/span><\/td>\n4.01 (2.34)<\/span><\/td>\n<\/tr>\n
\u58ca\u75bd<\/span><\/td>\n62<\/span><\/td>\n13.45 (10.47\u201317.28)<\/span><\/td>\n13.43<\/span><\/td>\n705.22<\/span><\/td>\n13.29 (10.77)<\/span><\/td>\n3.73 (2.07)<\/span><\/td>\n<\/tr>\n
\u814e\u76c2\u814e\u708e<\/span><\/td>\n60<\/span><\/td>\n9.88 (7.66\u201312.75)<\/span><\/td>\n9.87<\/span><\/td>\n474.35<\/span><\/td>\n9.80 (7.92)<\/span><\/td>\n3.29 (1.63)<\/span><\/td>\n<\/tr>\n
\u5c3f\u8def\u611f\u67d3\u75c7<\/span><\/td>\n744<\/span><\/td>\n6.39 (5.94\u20136.87)<\/span><\/td>\n6.29<\/span><\/td>\n3304.30<\/span><\/td>\n6.27 (5.90)<\/span><\/td>\n2.65 (0.98)<\/span><\/td>\n<\/tr>\n
\u80c3\u8178\u708e<\/span><\/td>\n45<\/span><\/td>\n4.28 (3.19\u20135.73)<\/span><\/td>\n4.27<\/span><\/td>\n112.43<\/span><\/td>\n4.26 (3.33)<\/span><\/td>\n2.09 (0.42)<\/span><\/td>\n<\/tr>\n
\u80c3\u8178\u969c\u5bb3<\/span><\/td>\n\u81b5\u708e<\/span><\/td>\n213<\/span><\/td>\n5.58 (4.88\u20136.39)<\/span><\/td>\n5.56<\/span><\/td>\n793.86<\/span><\/td>\n5.54 (4.95)<\/span><\/td>\n2.47 (0.80)<\/span><\/td>\n<\/tr>\n
\u6025\u6027\u81b5\u708e<\/span><\/td>\n74<\/span><\/td>\n4.78 (3.81\u20136.01)<\/span><\/td>\n4.78<\/span><\/td>\n220.05<\/span><\/td>\n4.76 (3.93)<\/span><\/td>\n2.25 (0.58)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u4e0a\u306e\u8868\u306e\u8d64\u5b57\u306f\u533b\u85ac\u54c1\u30e9\u30d9\u30eb\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u306a\u3044\u4e88\u671f\u3057\u306a\u3044\u30b7\u30b0\u30ca\u30eb\u3067\u3059\u3002\u30a2\u30e1\u30ea\u30ab\u3067\u306f\u8133\u6897\u585e\u304c\u8a18\u8f09\u3055\u308c\u3066\u3044\u306a\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u6295\u4e0e\u3067\u3001\u5fc3\u81d3\u624b\u8853\u304c\u5927\u304d\u304f\u5897\u52a0\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u306d\u3002\u610f\u8b58\u306e\u5909\u6027\u72b6\u614b\u72b6\u614b\u3068\u3044\u3046\u306e\u306f\u3088\u304f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u8131\u6c34\u306b\u4f34\u3046\u8133\u8840\u6d41\u306e\u6e1b\u5c11\u3067\u8d77\u304d\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u306d\u3002\u81b5\u708e\u3082\u5897\u52a0\u3059\u308b\u3088\u3046\u3067\u3059\u3002<\/span><\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u306e\u767a\u73fe\u6642\u671f\u3067\u3059\u3002\u672a\u5831\u544a\u307e\u305f\u306f\u767a\u73fe\u6642\u671f\u4e0d\u660e\u306e\u5831\u544a\u3092\u9664\u304f\u3068\u3001\u5408\u8a084,112\u4ef6\u306e\u767a\u73fe\u6642\u671f\u304c\u5831\u544a\u3055\u308c\u3001\u767a\u73fe\u6642\u671f\u306e\u4e2d\u592e\u5024\u306f28\u65e5\u3067\u6709\u5bb3\u4e8b\u8c61\u306e\u75c7\u4f8b\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u6295\u4e0e\u958b\u59cb\u5f8c1\u304b\u6708\u4ee5\u5185\uff0851.36%\uff09\u30012\u304b\u6708\u4ee5\u5185\uff089.10%\uff09\u3001\u304a\u3088\u30733\u304b\u6708\u4ee5\u5185\uff085.93%\uff09\u306b\u767a\u751f\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u6295\u4e0e\u958b\u59cb\u304b\u30891\u5e74\u5f8c\u3082\u6709\u5bb3\u4e8b\u8c61\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001\u305d\u306e\u5272\u5408\u306f13.74%\u3067\u3042\u3063\u305f\u3053\u3068\u3082\u6ce8\u76ee\u306b\u5024\u3057\u307e\u3059\u3002<\/p>\n

SGLT-2\u963b\u5bb3\u5264\u306f\u6162\u6027\u5fc3\u4e0d\u5168\u307e\u305f\u306f\u6162\u6027\u814e\u81d3\u75c5\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u3082\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u814e\u4fdd\u8b77\u4f5c\u7528\u304c\u3042\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u306e\u306b\u3001\u65e5\u672c\u306e\u6dfb\u4ed8\u6587\u66f8\u3067\u306f\u3001\u300ceGFR\u304c20mL\/min\/1.73m2\u672a\u6e80\u306e\u60a3\u8005\u3067\u306f\u3001\u6295\u4e0e\u306e\u5fc5\u8981\u6027\u3092\u614e\u91cd\u306b\u5224\u65ad\u3059\u308b\u3053\u3068\u3002\u672c\u5264\u6295\u4e0e\u4e2d\u306beGFR\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u814e\u6a5f\u80fd\u969c\u5bb3\u304c\u60aa\u5316\u3059\u308b\u304a\u305d\u308c\u304c\u3042\u308b\u3002eGFR\u304c20mL\/min\/1.73m2\u672a\u6e80\u306e\u60a3\u8005\u53c8\u306f\u900f\u6790\u3092\u8981\u3059\u308b\u814e\u6a5f\u80fd\u969c\u5bb3\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u81e8\u5e8a\u8a66\u9a13\u306f\u5b9f\u65bd\u3057\u3066\u3044\u306a\u3044\u3002<\/span>\u300d\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u5f53\u306e\u610f\u5473\u3067\u8a00\u3048\u3070\u814e\u4fdd\u8b77\u4f5c\u7528\u306f\u7121\u3044\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u8981\u3059\u308b\u306b\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3055\u305b\u3066\u3001\u305d\u306e\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u6709\u5bb3\u6027\u3092\u8efd\u6e1b\u3057\u3066\u3044\u308b\u3060\u3051\u306e\u8a71\u3067\u3059\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308c\u3070\u3001\u4e0a\u306e\u3088\u3046\u306a\u6709\u5bb3\u4e8b\u8c61\u3082\u8d77\u3053\u3089\u305a\u306b\u3001\u8840\u7cd6\u5024\u3082\u4e0a\u304c\u3089\u305a\u306b\u3001\u5fc3\u81d3\u3082\u814e\u81d3\u3082\u4fdd\u8b77\u3067\u304d\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u526f\u4f5c\u7528\u306e\u306a\u3044\u85ac\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u300cThe real-world safety profile of empagliflozin: a disproportionality analysis based on the FDA Adverse Event Reporting System (FAERS) database\u300d<\/span><\/p>\n

\u300c\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306e\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\uff1aFDA\u6709\u5bb3\u4e8b\u8c61\u5831\u544a\u30b7\u30b9\u30c6\u30e0\uff08FAERS\uff09\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u57fa\u3065\u304f\u4e0d\u5747\u8861\u5206\u6790\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u533b\u7642\u306e\u4e2d\u3067\u306f\u3001SGLT-2\u963b\u5bb3\u5264\u306f\u7d20\u6674\u3089\u3057\u3044\u85ac\u306e\u3088\u3046\u306b\u3082\u3066\u306f\u3084\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306e\u85ac\u3068\u3057\u3066\u3060\u3051\u3067\u306a\u304f\u3001\u5fc3\u4e0d\u5168\u3084\u6162\u6027\u814e\u81d3\u75c5\u306e\u85ac\u3068\u3057\u3066\u3082\u9069\u5fdc\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u304b\u3089\u304f\u308a\u306f\u5225\u3068\u3057\u3066\u3001\u3053\u306eSGLT-2\u963b\u5bb3\u5264\u306f\u3084\u3063\u3071\u308a\u85ac\u3067\u3042\u308a\u3001<\/p>\n","protected":false},"author":1,"featured_media":31919,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,150,161],"tags":[19,32,45,98],"class_list":["post-31878","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-diabetes","category-ketone","tag-toushitsuseigen","tag-diabetes","tag-side","tag-98","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/08\/23158157_s.jpg?fit=480%2C640&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-8ia","jetpack-related-posts":[{"id":23257,"url":"https:\/\/promea2014.com\/blog\/?p=23257","url_meta":{"origin":31878,"position":0},"title":"SGLT-2\u963b\u5bb3\u85ac\u306b\u4f34\u3046\u6025\u6027\u81b5\u708e\u3068\u6b7b\u4ea1\u30ea\u30b9\u30af","author":"Dr.Shimizu","date":"2023\u5e748\u670810\u65e5","format":false,"excerpt":"\u7cd6\u5c3f\u75c5\u85ac\u306eSGLT-2\u963b\u5bb3\u85ac\u306f\u3044\u304f\u3064\u3082\u306e\u5229\u70b9\u304c\u5f37\u8abf\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u5b8c\u5168\u306b\u5b89\u5168\u306a\u85ac\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002\u2026","rel":"","context":"\u30b9\u30bf\u30c1\u30f3","block_context":{"text":"\u30b9\u30bf\u30c1\u30f3","link":"https:\/\/promea2014.com\/blog\/?cat=149"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/08\/25667314_s.jpg?fit=640%2C459&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/08\/25667314_s.jpg?fit=640%2C459&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/08\/25667314_s.jpg?fit=640%2C459&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":24045,"url":"https:\/\/promea2014.com\/blog\/?p=24045","url_meta":{"origin":31878,"position":1},"title":"\u7cd6\u5c3f\u75c5\u85ac\uff1f\u3084\u305b\u85ac\uff1fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u3000\u305d\u306e7\u3000\u7532\u72b6\u817a\u304c\u3093","author":"Dr.Shimizu","date":"2023\u5e7411\u670827\u65e5","format":false,"excerpt":"GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u69d8\u3005\u306a\u526f\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u300c\u305d\u306e1\u300d\u300c\u305d\u306e2\u300d\u300c\u305d\u306e3\u300d\u300c\u305d\u306e4\u300d\u300c\u305d\u306e5\u300d\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/23214183_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/23214183_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/23214183_s.jpg?fit=640%2C426&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":23242,"url":"https:\/\/promea2014.com\/blog\/?p=23242","url_meta":{"origin":31878,"position":2},"title":"\u7cd6\u5c3f\u75c5\u85ac\uff1f\u3084\u305b\u85ac\uff1fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u3000\u305d\u306e1","author":"Dr.Shimizu","date":"2023\u5e747\u670810\u65e5","format":false,"excerpt":"2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3067\u3042\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u6700\u8fd1\u3067\u306f\u30c0\u30a4\u30a8\u30c3\u30c8\u76ee\u7684\u306e\u3044\u308f\u3086\u308b\u300c\u3084\u305b\u85ac\u300d\u3068\u3057\u3066\u3082\u9069\u5fdc\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26977714_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26977714_s.jpg?fit=640%2C426&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26977714_s.jpg?fit=640%2C426&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":24247,"url":"https:\/\/promea2014.com\/blog\/?p=24247","url_meta":{"origin":31878,"position":3},"title":"\u3044\u307e\u3060\u306b\u71fb\u308bSGLT-2\u963b\u5bb3\u85ac\u306e\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af","author":"Dr.Shimizu","date":"2023\u5e7411\u67082\u65e5","format":false,"excerpt":"\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85acSGLT2\u963b\u5bb3\u85ac\u306f\u4e0b\u80a2\u5207\u65ad\u3092\u5897\u52a0\u3055\u305b\u308b\u304b\u3082\u3057\u308c\u306a\u3044\uff01\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001SGL\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/24629554_s.jpg?fit=640%2C451&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/24629554_s.jpg?fit=640%2C451&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/11\/24629554_s.jpg?fit=640%2C451&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":23321,"url":"https:\/\/promea2014.com\/blog\/?p=23321","url_meta":{"origin":31878,"position":4},"title":"\u7cd6\u5c3f\u75c5\u85ac\uff1f\u3084\u305b\u85ac\uff1fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u3000\u305d\u306e4\u3000\u304c\u3093","author":"Dr.Shimizu","date":"2023\u5e747\u670821\u65e5","format":false,"excerpt":"\u3053\u308c\u307e\u3067\u300c\u305d\u306e1\u300d\u300c\u305d\u306e2\u300d\u300c\u305d\u306e3\u300d\u3092\u66f8\u3044\u3066\u304d\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u305d\u306e\u7d9a\u304d\u3067\u3059\u3002\u6700\u3082\u526f\u4f5c\u7528\u3068\u3057\u3066\u6050\u308d\u3057\u3044\u2026","rel":"","context":"\u7cd6\u5c3f\u75c5","block_context":{"text":"\u7cd6\u5c3f\u75c5","link":"https:\/\/promea2014.com\/blog\/?cat=150"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26883909_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26883909_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2023\/07\/26883909_s.jpg?fit=640%2C427&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":33237,"url":"https:\/\/promea2014.com\/blog\/?p=33237","url_meta":{"origin":31878,"position":5},"title":"SGLT-2\u963b\u5bb3\u85ac\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306e\u8840\u4e2d\u306e\u8102\u8cea\u306e\u5909\u5316","author":"Dr.Shimizu","date":"2025\u5e7412\u670829\u65e5","format":false,"excerpt":"SGLT-2\u963b\u5bb3\u85ac\u306f\u3001\u73fe\u5728GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u4e26\u3093\u3067\u3001\u7cd6\u5c3f\u75c5\u306e\u85ac\u306e\u82b1\u5f62\uff08\u8868\u73fe\u304c\u53e4\u3044\uff1f\uff09\u3067\u3059\u3002\u3067\u306f\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/12\/24137854_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/12\/24137854_s.jpg?fit=640%2C480&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/12\/24137854_s.jpg?fit=640%2C480&ssl=1&resize=525%2C300 1.5x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31878"}],"version-history":[{"count":11,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31878\/revisions"}],"predecessor-version":[{"id":32133,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31878\/revisions\/32133"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=\/wp\/v2\/media\/31919"}],"wp:attachment":[{"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31878"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31878"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/promea2014.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}