{"id":32626,"date":"2025-12-05T12:05:55","date_gmt":"2025-12-05T03:05:55","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=32626"},"modified":"2025-12-05T12:05:55","modified_gmt":"2025-12-05T03:05:55","slug":"lpa%e3%81%af%e6%9c%ac%e5%bd%93%e3%81%ab%e8%b6%85%e6%82%aa%e7%8e%89%ef%bc%9f%e3%80%80%e7%b5%90%e5%b1%80%e5%bf%83%e8%a1%80%e7%ae%a1%e3%83%aa%e3%82%b9%e3%82%af%e5%9b%a0%e5%ad%90%e3%81%ab%e3%81%af","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=32626","title":{"rendered":"Lp(a)\u306f\u672c\u5f53\u306b\u8d85\u60aa\u7389\uff1f\u3000\u7d50\u5c40\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u306b\u306f\u306a\u308a\u5f97\u306a\u3044\u304b\u3082"},"content":{"rendered":"<p>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u6b21\u306b\u8105\u3057\u306b\u4f7f\u308f\u308c\u305d\u3046\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\uff08a\uff09\uff08Lp(a)\uff09\u3067\u3059\u304c\u3001\u672c\u5f53\u306b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30a6\u30a8\u30b9\u30c8\u30d2\u30c3\u30d7\u6bd4\uff08WHR\uff09\u306a\u3069\u306e\u80a5\u6e80\u6307\u6a19\u304cLp(a)\u3068\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\uff08ASCVD\uff09\u306e\u95a2\u4fc2\u3092\u5909\u5316\u3055\u305b\u308b\u304b\u3069\u3046\u304b\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u591a\u6c11\u65cf\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u7814\u7a76\uff08MESA\uff09\u306e\u53c2\u52a0\u80054,652\u4eba\uff08\u5e73\u5747\u5e74\u9f6262\u6b73\uff09\u304c\u5bfe\u8c61\u3067\u3059\u3002<\/p>\n<p>Lp(a) &lt; 50 mg\/dL\u304b\u3064WHR &lt;90\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3001Lp(a) &lt; 50 mg\/dL\u304b\u3064WHR \u2265 90 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3001Lp(a) \u2265 50 mg\/dL\u304b\u3064WHR &lt;90 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3001Lp(a) \u2265 50 mg\/dL\u304b\u3064WHR \u2265 90 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e4\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\u307e\u3057\u305f\u3002\u3002\u3061\u306a\u307f\u306bWHR &lt;90\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u5e73\u5747\u5024\u306fWHR0.90\u3067\u3001WHR \u2265 90 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306f1.04\u3067\u3057\u305f\u3002WHR \u306e 90 \u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306f\u7537\u6027\u3067 1.03\u3001\u5973\u6027\u3067 1.00 \u3067\u3057\u305f\u3002\u7537\u6027\u306f0.90\u3001\u5973\u6027\u306f0.85\u3092\u8d85\u3048\u308b\u3068\u80a5\u6e80\u3068\u5224\u65ad\u3055\u308c\u307e\u3059\u306e\u3067\u300190\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u672a\u6e80\u3067\u3082\u80a5\u6e80\u306e\u4eba\u3092\u542b\u3093\u3067\u3044\u307e\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"32627\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=32627\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?fit=565%2C405&amp;ssl=1\" data-orig-size=\"565,405\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Lp(a)\u30a6\u30bd1-s2.0-S0033062025000301-gr1\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?fit=300%2C215&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?fit=565%2C405&amp;ssl=1\" class=\"alignnone size-full wp-image-32627\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?resize=565%2C405\" alt=\"\" width=\"565\" height=\"405\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?w=565&amp;ssl=1 565w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/e4e99f2cef2f33fbee8d6b60e0641f72.jpg?resize=300%2C215&amp;ssl=1 300w\" sizes=\"auto, (max-width: 565px) 100vw, 565px\" \/><\/a><\/p>\n<p>\u4e2d\u592e\u502417.4\u5e74\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u306b792\u4f8b\u306eASCVD\u75c7\u4f8b\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u4e0a\u306e\u56f3\u306f\u3001\u30b0\u30eb\u30fc\u30d7\u5225\u306eASCVD\u7d2f\u7a4d\u767a\u751f\u7387\u3067\u3059\u3002<\/p>\n<p>\u5fc3\u8840\u7ba1\u75be\u60a3\u767a\u75c7\u30ea\u30b9\u30af\u306f\u3001Lp(a) &lt;50 mg\/dL\u304b\u3064WHR &lt; 90\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u3001Lp(a) &lt;50 mg\/dL\u304b\u3064WHR \u226590\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u5834\u5408\u306f1.14\u500d\uff08\u6709\u610f\u5dee\u306a\u3057\uff09\u3001Lp(a) \u226550 mg\/dL\u304b\u3064WHR &lt;90\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u5834\u5408\u306f1.15\u500d\uff08\u6709\u610f\u5dee\u306a\u3057\uff09\u3001Lp(a) \u226550 mg\/dL\u304b\u3064WHR \u226590\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u4eba\u306e\u5834\u5408\u306f2.34\u500d\u3067\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"32628\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=32628\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?fit=801%2C208&amp;ssl=1\" data-orig-size=\"801,208\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"1-s2.0-S0033062025000301-gr2\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?fit=300%2C78&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?fit=640%2C166&amp;ssl=1\" class=\"alignnone size-full wp-image-32628\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?resize=640%2C166\" alt=\"\" width=\"640\" height=\"166\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?w=801&amp;ssl=1 801w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?resize=300%2C78&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/1-s2.0-S0033062025000301-gr2.jpg?resize=768%2C199&amp;ssl=1 768w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u3001WHR\u30923\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\u305f\u3068\u304d\u306e\u3001Lp(a)\u3068\u306e\u95a2\u9023\u3067\u3001ASCVD\u7d2f\u7a4d\u767a\u751f\u7387\u304c\u3069\u3046\u306a\u308b\u304b\u3092\u898b\u3066\u3044\u307e\u3059\u3002WHR\u304c\u4f4e\u3044\u30b0\u30eb\u30fc\u30d7\u3068\u4e2d\u9593\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001Lp(a) \u2265 50 mg\/dL\u3068Lp(a) &lt; 50 mg\/dL\u306eASCVD\u7d2f\u7a4d\u767a\u751f\u7387\u306b\u9055\u3044\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001WHR\u304c\u6700\u3082\u9ad8\u3044\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001Lp(a) \u2265 50 mg\/dL\u306e\u65b9\u304cLp(a) &lt; 50 mg\/dL\u3088\u308a\u3082ASCVD\u7d2f\u7a4d\u767a\u751f\u7387\u304c\u6709\u610f\u306b\u9ad8\u304f\u306a\u308a\u3001\u30ea\u30b9\u30af\u306f1.60\u500d\u3067\u3057\u305f\u3002<\/p>\n<p>\u7537\u5973\u5225\u3067\u898b\u308b\u3068\u3001Lp(a) &lt;50 mg\/dL\u304b\u3064WHR &lt; 90\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u3001Lp(a) \u226550 mg\/dL\u304b\u3064WHR \u226590\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u4eba\u306fASCVD\u30ea\u30b9\u30af\u304c\u3001\u5973\u6027\u30673.43\u500d\u3001\u7537\u6027\u30671.97\u500d\u3067\u3057\u305f\u3002\u51a0\u52d5\u8108\u75be\u60a3\u30ea\u30b9\u30af\u3060\u3051\u3092\u898b\u308b\u3068\u3001Lp(a) \u226550 mg\/dL\u304b\u3064WHR \u226590\u30d1\u30fc\u30bb\u30f3\u30bf\u30a4\u30eb\u306e\u4eba\u306f\u3001\u5973\u6027\u30675.09\u500d\u3001\u7537\u6027\u30672.29\u500d\u3067\u3057\u305f\u3002<\/p>\n<p>\u3064\u307e\u308a\u3001Lp(a)\u304c\u9ad8\u3044\u5834\u5408\u3001\u305d\u308c\u306fWHR\u304c\u975e\u5e38\u306b\u9ad8\u3044\u30b0\u30eb\u30fc\u30d7\u306e\u5834\u5408\u306e\u307f\u3067\u30ea\u30b9\u30af\u56e0\u5b50\u3068\u306a\u308b\u3060\u3051\u3067\u3059\u3002\u9006\u306b\u8a00\u3048\u3070\u3001Lp(a)\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e3b\u8981\u56e0\u3068\u306f\u306a\u308a\u5f97\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n<p>\u30a6\u30a8\u30b9\u30c8\u30d2\u30c3\u30d7\u6bd4\u306f\u8179\u90e8\u80a5\u6e80\u3001\u5185\u81d3\u8102\u80aa\u3092\u53cd\u6620\u3057\u3066\u3044\u307e\u3059\u3002\u5185\u81d3\u8102\u80aa\u306e\u5897\u52a0\u306e\u65b9\u304c\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u5371\u967a\u306a\u306e\u3067\u3059\u3002<\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=32581\" target=\"_blank\" rel=\"noopener\">Lp(a)\u306b\u5bfe\u3059\u308b\u98df\u4e8b\u3084\u904b\u52d5\u306a\u3069\u306e\u5f71\u97ff<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001Lp(a)\u306f90%\u304c\u907a\u4f1d\u7684\u306b\u6c7a\u307e\u3063\u3066\u3044\u308b\u3068\u8a00\u308f\u308c\u306a\u304c\u3089\u3001\u98df\u4e8b\u3084\u904b\u52d5\u3067\u5927\u304d\u304f\u5909\u52d5\u3057\u307e\u3059\u3002\u7279\u306b\u533b\u7642\u696d\u754c\u304c\u76ee\u306e\u6575\u306b\u3059\u308b\u8102\u8cea\u3001\u98fd\u548c\u8102\u80aa\u9178\u306e\u6442\u53d6\u91cf\u5897\u52a0\u306fLp(a)\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=22391\" target=\"_blank\" rel=\"noopener\">\u9838\u52d5\u8108\u30d7\u30e9\u30fc\u30af\u306b\u95a2\u4fc2\u3059\u308b\u306e\u306fLp(a)\u3088\u308a\u3082\u8840\u7cd6\u5024<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001Lp(a)\u3088\u308a\u3082\u91cd\u8981\u306a\u306e\u306f\u8010\u7cd6\u80fd\u969c\u5bb3\u306e\u7a0b\u5ea6\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>Lp(a)\u306e\u6570\u5024\u3092\u6574\u3048\u308b\u3053\u3068\u306f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3068\u540c\u69d8\u306b\u3001\u610f\u5473\u304c\u306a\u3044\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u308c\u3088\u308a\u3082\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3001\u8840\u7cd6\u5024\u306e\u5909\u52d5\u3092\u6291\u3048\u3001\u5185\u81d3\u8102\u80aa\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u306e\u65b9\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>Lp(a)\u304c\u9ad8\u5024\u3060\u3068\u3001\u533b\u5e2b\u304b\u3089\u5f37\u3044\u8105\u3057\u304c\u5165\u308b\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001Lp(a)\u306f\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u306f\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u5fc3\u8840\u7ba1\u75be\u60a3\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cWaist to hip ratio modifies the cardiovascular risk of lipoprotein (a): Insights from MESA\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u30a6\u30a8\u30b9\u30c8\u30d2\u30c3\u30d7\u6bd4\u306f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\uff08a\uff09\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u5909\u5316\u3055\u305b\u308b\uff1aMESA\u304b\u3089\u306e\u6d1e\u5bdf\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40081639\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u6b21\u306b\u8105\u3057\u306b\u4f7f\u308f\u308c\u305d\u3046\u306a\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\uff08a\uff09\uff08Lp(a)\uff09\u3067\u3059\u304c\u3001\u672c\u5f53\u306b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f 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