{"id":33081,"date":"2025-12-10T08:41:15","date_gmt":"2025-12-09T23:41:15","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=33081"},"modified":"2025-12-10T08:41:15","modified_gmt":"2025-12-09T23:41:15","slug":"ppi%ef%bc%88%e3%83%97%e3%83%ad%e3%83%88%e3%83%b3%e3%83%9d%e3%83%b3%e3%83%97%e9%98%bb%e5%ae%b3%e8%96%ac%ef%bc%89%e3%81%b8%e3%81%ae%e6%9b%9d%e9%9c%b2%e3%81%a8%e9%ab%98%e8%a1%80%e5%9c%a7%e3%81%a8","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=33081","title":{"rendered":"PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u3078\u306e\u66dd\u9732\u3068\u9ad8\u8840\u5727\u3068\u306e\u95a2\u9023"},"content":{"rendered":"

PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u306f3\u5927\u30de\u30c3\u30c1\u30dd\u30f3\u30d7\u85ac\u306e\u4e00\u3064\u3067\u3059\u3002\u69d8\u3005\u306a\u554f\u984c\u3092\u8d77\u3053\u3059PPI\u3067\u3059\u304c\u3001\u9ad8\u8840\u5727\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001WHO \u306e\u85ac\u7269\u5b89\u5168\u6027\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3067\u3042\u308b VigiBase \u304b\u3089\u306e\u5b9f\u969b\u306e\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u306f\u3001PPI\u95a2\u9023\u9ad8\u8840\u5727\u306e\u5831\u544a\u304c26,587\u4ef6\uff082.3%\uff09\u542b\u307e\u308c\u3066\u304a\u308a\u300163.3%\u304c\u5973\u6027\u3067\u300145\uff5e64\u6b73\u306e\u30b0\u30eb\u30fc\u30d7\u306741.4%\u3068\u6700\u3082\u983b\u7e41\u306b\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u5831\u544a\u30aa\u30c3\u30ba\u6bd4\uff08ROR\uff09\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\u85ac\u5264\u540d<\/span><\/td>\n\u591a\u5909\u91cf\u89e3\u6790<\/span><\/td>\n<\/tr>\n
ROR<\/span><\/td>\n95%\u4fe1\u983c\u533a\u9593<\/span><\/td>\n<\/tr>\n<\/thead>\n
\u30c7\u30ad\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.17<\/span><\/td>\n\uff081.06\u304b\u30891.28\uff09<\/span><\/td>\n<\/tr>\n
\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.25<\/span><\/td>\n\uff081.22\u304b\u30891.29\uff09<\/span><\/td>\n<\/tr>\n
\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n0.99<\/span><\/td>\n\uff080.96\u304b\u30891.03\uff09<\/span><\/td>\n<\/tr>\n
\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.09<\/span><\/td>\n\uff081.06\u304b\u30891.11\uff09<\/span><\/td>\n<\/tr>\n
\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.35<\/span><\/td>\n\uff081.32\u304b\u30891.38\uff09<\/span><\/td>\n<\/tr>\n
\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.34<\/span><\/td>\n\uff081.26\u304b\u30891.42\uff09<\/span><\/td>\n<\/tr>\n
PPI\u30af\u30e9\u30b9<\/span><\/td>\n1.19<\/span><\/td>\n\uff081.17\u304b\u30891.20\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306e\u3088\u3046\u306b\u3001\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb\u4ee5\u5916\u306e\u5168\u3066\u306ePPI\u306f\u9ad8\u8840\u5727\u306e\u5831\u544a\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u85ac\u5264\u540d<\/span><\/td>\n\u85ac\u7269\u66dd\u9732\u306b\u3088\u308b\u9ad8\u8840\u5727<\/span><\/td>\n<\/tr>\n
\u7528\u91cf\u2264\u4e2d\u592e\u5024<\/span><\/td>\n\u7528\u91cf > \u4e2d\u592e\u5024<\/span><\/td>\n<\/tr>\n
\u591a\u5909\u91cf\u89e3\u6790<\/span><\/td>\n\u591a\u5909\u91cf\u89e3\u6790<\/span><\/td>\n<\/tr>\n
ROR<\/span><\/td>\n95%\u4fe1\u983c\u533a\u9593<\/span><\/td>\nROR<\/span><\/td>\n95%\u4fe1\u983c\u533a\u9593<\/span><\/td>\n<\/tr>\n<\/thead>\n
\u30c7\u30ad\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.63<\/span><\/td>\n\uff081.32\u304b\u30892.01\uff09<\/span><\/td>\n1.92<\/span><\/td>\n\uff080.26\u304b\u308914.35\uff09<\/span><\/td>\n<\/tr>\n
\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.33<\/span><\/td>\n\uff081.23\u304b\u30891.44\uff09<\/span><\/td>\n1.88<\/span><\/td>\n\uff081.59\u304b\u30892.24\uff09<\/span><\/td>\n<\/tr>\n
\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n0.99<\/span><\/td>\n\uff080.88\u304b\u30891.11\uff09<\/span><\/td>\n1.47<\/span><\/td>\n\uff081.11\u304b\u30891.95\uff09<\/span><\/td>\n<\/tr>\n
\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.08<\/span><\/td>\n\uff081.01\u304b\u30891.17\uff09<\/span><\/td>\n1.27<\/span><\/td>\n\uff081.17\u304b\u30891.38\uff09<\/span><\/td>\n<\/tr>\n
\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.23<\/span><\/td>\n\uff081.15\u304b\u30891.31\uff09<\/span><\/td>\n1.37<\/span><\/td>\n\uff081.18\u304b\u30891.59\uff09<\/span><\/td>\n<\/tr>\n
\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n0.92<\/span><\/td>\n\uff080.76\u304b\u30891.11\uff09<\/span><\/td>\n1.09<\/span><\/td>\n\uff080.67\u304b\u30891.76\uff09<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u306e\u8868\u306f\u3001\u85ac\u5264\u306e\u7528\u91cf\u3068\u306e\u95a2\u9023\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u591a\u304f\u306ePPI\u306f\u7528\u91cf\u304c\u4e2d\u592e\u5024\u3092\u8d85\u3048\u305f\u65b9\u304c\u3001\u9ad8\u8840\u5727\u306e\u5831\u544a\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

\n

\u4e0b\u306e\u8868\u306f\u3001PPI\u6295\u4e0e\u5f8c\u306e\u9ad8\u8840\u5727\u767a\u75c7\u307e\u3067\u306e\u6642\u9593\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<\/div>\n\n\n\n\n\n\n\n\n\n\n
\u85ac<\/span><\/td>\n\u65e5\u6570\u306e\u4e2d\u592e\u5024\u3001IQR\uff09<\/span><\/td>\n<\/tr>\n<\/thead>\n
\u30c7\u30ad\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n11.0 (0.0\u201323.0)<\/span><\/td>\n<\/tr>\n
\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n2.0 (0.0\uff5e36.0)<\/span><\/td>\n<\/tr>\n
\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n0.6 (0.0\u20137.2)<\/span><\/td>\n<\/tr>\n
\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n0.0 (0.0\uff5e3.0)<\/span><\/td>\n<\/tr>\n
\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.0 (0.0\uff5e6.0)<\/span><\/td>\n<\/tr>\n
\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb<\/span><\/td>\n1.0 (0.0\u201330.5)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u30c7\u30ad\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb\u3092\u9664\u3044\u3066\u3001\u5168\u3066\u306ePPI\u6295\u4e0e\u304b\u3089\u9ad8\u8840\u5727\u767a\u75c7\u307e\u3067\u4e2d\u592e\u5024\u30672\u65e5\u4ee5\u5185\u3067\u3057\u305f\u3002\u3059\u3054\u3044\u5373\u52b9\u6027\u3067\u3059\u306d\u3002<\/span><\/p>\n

PPI\u304c\u9ad8\u8840\u5727\u3092\u8a98\u767a\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u3057\u3066\u3001\u8840\u7ba1\u5185\u306e\u4e00\u9178\u5316\u7a92\u7d20\uff08NO\uff09\u7523\u751f\u3092\u963b\u5bb3\u3057\u305f\u308a\u3001\u8840\u7ba1\u306e\u6d3b\u6027\u9178\u7d20\u751f\u6210\u306e\u5897\u52a0\u3092\u4ecb\u3057\u305f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u4fc3\u9032\u3057\u3001\u5185\u76ae\u4f9d\u5b58\u6027\u8840\u7ba1\u62e1\u5f35\u3092\u963b\u5bb3\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u69d8\u3005\u306a\u5371\u967a\u3092\u5897\u52a0\u3055\u305b\u308bPPI\u306f\u3067\u304d\u308b\u9650\u308a\u907f\u3051\u308b\u3079\u304d\u3067\u3059\u3002\u533b\u5e2b\u306f\u672c\u5f53\u306f\u77ed\u671f\u9593\u3067\u3084\u3081\u308b\u3079\u304dPPI\u3092\u30c0\u30e9\u30c0\u30e9\u3068\u51e6\u65b9\u3057\u7d9a\u3051\u307e\u3059\u3002<\/p>\n

\u307e\u305a\u306f\u6700\u521d\u306b\u98f2\u307e\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u3053\u3068\u3002\u3082\u3057\u98f2\u307f\u59cb\u3081\u3066\u3057\u307e\u3063\u305f\u3089\u3001\u3067\u304d\u308b\u9650\u308a\u65e9\u671f\u306b\u6b62\u3081\u308b\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308c\u3070\u3001\u307b\u3068\u3093\u3069\u306e\u4eba\u306fPPI\u304c\u4e0d\u5fc5\u8981\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u9577\u671f\u306b\u98f2\u3093\u3067\u3044\u308b\u4eba\u306f\u3057\u3070\u3089\u304f\u30ea\u30d0\u30a6\u30f3\u30c9\u306b\u8010\u3048\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u300cAssociation between exposure to proton pump inhibitors and hypertension: a descriptive and disproportionality analysis of VigiBase\u300d<\/span><\/p>\n

\u300c\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u3078\u306e\u66dd\u9732\u3068\u9ad8\u8840\u5727\u3068\u306e\u95a2\u9023\uff1aVigiBase\u306e\u8a18\u8ff0\u7684\u304a\u3088\u3073\u4e0d\u5747\u8861\u6027\u5206\u6790\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u306f3\u5927\u30de\u30c3\u30c1\u30dd\u30f3\u30d7\u85ac\u306e\u4e00\u3064\u3067\u3059\u3002\u69d8\u3005\u306a\u554f\u984c\u3092\u8d77\u3053\u3059PPI\u3067\u3059\u304c\u3001\u9ad8\u8840\u5727\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002 \u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001WHO \u306e\u85ac\u7269\u5b89\u5168\u6027\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3067\u3042\u308b VigiBase \u304b\u3089\u306e\u5b9f\u969b\u306e\u30c7\u30fc\u30bf\u3092\u4f7f\u7528<\/p>\n","protected":false},"author":1,"featured_media":33084,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,156,4],"tags":[100,19,33,45,98],"class_list":["post-33081","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-ppi","category-4","tag-100","tag-toushitsuseigen","tag-ppi","tag-side","tag-98","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/12\/26959094_s.jpg?fit=640%2C427&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-8Bz","jetpack-related-posts":[{"id":31415,"url":"https:\/\/promea2014.com\/blog\/?p=31415","url_meta":{"origin":33081,"position":0},"title":"\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff08PPI\uff09\u306b\u3088\u308b\u7b4b\u8089\u306e\u969c\u5bb3","author":"Dr.Shimizu","date":"2025\u5e748\u670828\u65e5","format":false,"excerpt":"\u7b4b\u8089\u306e\u969c\u5bb3\u306e\u526f\u4f5c\u7528\u306f\u30b9\u30bf\u30c1\u30f3\u306e\u5c02\u58f2\u7279\u8a31\uff08\u8868\u73fe\u304c\u53e4\u3044\uff1f\uff09\u3060\u3068\u601d\u3044\u307e\u3057\u305f\u304c\u3001\u3069\u3046\u3084\u3089\u3082\u3046\u4e00\u3064\u306e\u30de\u30c3\u30c1\u30dd\u30f3\u2026","rel":"","context":"\u30b9\u30bf\u30c1\u30f3","block_context":{"text":"\u30b9\u30bf\u30c1\u30f3","link":"https:\/\/promea2014.com\/blog\/?cat=149"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/07\/1265807_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2025\/07\/1265807_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 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