{"id":33237,"date":"2025-12-29T08:31:45","date_gmt":"2025-12-28T23:31:45","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=33237"},"modified":"2025-12-29T08:31:45","modified_gmt":"2025-12-28T23:31:45","slug":"sglt-2%e9%98%bb%e5%ae%b3%e8%96%ac%e3%81%ab%e3%82%88%e3%82%8b%e7%b3%96%e5%b0%bf%e7%97%85%e3%81%ae%e8%a1%80%e4%b8%ad%e3%81%ae%e8%84%82%e8%b3%aa%e3%81%ae%e5%a4%89%e5%8c%96","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=33237","title":{"rendered":"SGLT-2\u963b\u5bb3\u85ac\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306e\u8840\u4e2d\u306e\u8102\u8cea\u306e\u5909\u5316"},"content":{"rendered":"

SGLT-2\u963b\u5bb3\u85ac\u306f\u3001\u73fe\u5728GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u4e26\u3093\u3067\u3001\u7cd6\u5c3f\u75c5\u306e\u85ac\u306e\u82b1\u5f62\uff08\u8868\u73fe\u304c\u53e4\u3044\uff1f\uff09\u3067\u3059\u3002\u3067\u306f\u3001\u305d\u306e\u5b9f\u529b\u3001\u305d\u306e\u5f71\u97ff\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u306f\u300118\u6b73\u4ee5\u4e0a\u306e\u30a2\u30b8\u30a2\u4eba2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3057\u305f\u3001SGLT\u20102\u963b\u5bb3\u85ac\u306e\u52b9\u679c\u3092\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3059\u308b\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u3059\u30024,485\u4eba\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f17\u4ef6\uff08\u305d\u306e\u3046\u306114\u4ef6\u306f\u65e5\u672c\u306e\u7814\u7a76\uff09\u306eRCT\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002RCT\u306e\u671f\u9593\u306f12\u9031\u9593\u304b\u308924\u9031\u9593\u3067\u3057\u305f\u3002<\/p>\n

\u307e\u305a\u306f\u7cd6\u5c3f\u75c5\u306e\u85ac\u306a\u306e\u3067\u3001HbA1c\u306b\u3064\u3044\u3066\u3002SGLT\u20102\u963b\u5bb3\u85ac\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u3001HbA1c\u306f\u5e73\u5747\u30670.80%\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002\u305f\u3063\u305f0.8\u3067\u3059\u3002\u3057\u3087\u307c\u3044\u3067\u3059\u306d\u3002<\/p>\n

\u3067\u306f\u3001\u8840\u4e2d\u306e\u8102\u8cea\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\u4e2d\u6027\u8102\u80aa\u5024\u306f\u5e73\u5747\u306716.42mg\/dL\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002\u4e0b\u304c\u3089\u306a\u3044\u3088\u308a\u306f\u3044\u3044\u3067\u3059\u304c\u3001\u3057\u3087\u307c\u3044\u7d50\u679c\u3067\u3059\u3002<\/p>\n

HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f3.36mg\/dL\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u307e\u305f\u3057\u3087\u307c\u3044\u7d50\u679c\u3067\u3059\u3002<\/p>\n

LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f3.00mg\/dL\u5897\u52a0\u3057\u307e\u3057\u305f\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u308f\u305a\u304b\u3067\u3059\u304c\u5897\u52a0\u3067\u3059\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5897\u52a0\u3059\u308b\u306e\u306b\u3001\u5185\u79d1\u533b\u306f\u559c\u3093\u3067SGLT\u20102\u963b\u5bb3\u85ac\u3092\u4f7f\u3044\u307e\u3059\u3002\u307e\u308b\u3067\u3001\u3053\u308c\u307e\u3067\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4f4e\u3051\u308c\u3070\u4f4e\u3044\u307b\u3069\u826f\u3044\u3068\u8a00\u3063\u3066\u3044\u305f\u3053\u3068\u3092\u5fd8\u308c\u305f\u304b\u306e\u3088\u3046\u306b\u3002<\/p>\n

SGLT\u20102\u963b\u5bb3\u85ac\u306f\u69d8\u3005\u306a\u6709\u76ca\u306a\u52b9\u679c\u304c\u3042\u308b\u3088\u3046\u306b\u898b\u3048\u3001\u305d\u308c\u304c\u308f\u304b\u308b\u3068\u3001\u533b\u5e2b\u306f\u3053\u306e\u85ac\u3092\u4f7f\u3046\u4e0a\u3067\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5897\u52a0\u3057\u3066\u3057\u307e\u3046\u3053\u3068\u3092\u4f55\u3082\u6c17\u306b\u3057\u306a\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u6050\u3089\u304f\u306f\u30b9\u30bf\u30c1\u30f3\u3092\u4f7f\u3048\u3070\u826f\u3044\u3068\u3067\u3082\u601d\u3063\u3066\u3044\u308b\u304b\u3089\u306a\u306e\u3067\u3057\u3087\u3046\u3002\u305d\u308c\u3068\u3082\u3053\u308c\u304f\u3089\u3044\u306e\u5897\u52a0\u306a\u3089\u6c17\u306b\u3057\u306a\u3044\u3068\u3067\u3082\u8a00\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u305d\u3057\u3066\u3001\u3053\u308c\u307e\u3067\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u8cea\u306a\u3069\u306f\u5168\u304f\u6c17\u306b\u3057\u3066\u3044\u306a\u304b\u3063\u305f\u306e\u306b\u3001SGLT\u20102\u963b\u5bb3\u85ac\u304cLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5897\u52a0\u3055\u305b\u3066\u3082\u3001\u305d\u308c\u306f\u5371\u967a\u306a\u5c0f\u3055\u306asdLDL\u304c\u4f4e\u4e0b\u3059\u308b\u304b\u3089\u5065\u5eb7\u306b\u826f\u3044\u3068\u307e\u3067\u8003\u3048\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002\uff08\u3053\u3053<\/a>\u306a\u3069\u53c2\u7167\uff09\u90fd\u5408\u304c\u826f\u3044\u3067\u3059\u306d\u3002\u306a\u3093\u305b\u3001SGLT\u20102\u963b\u5bb3\u85ac\u306f\u5fc3\u4fdd\u8b77\u4f5c\u7528\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u306e\u3067\u3001\u3053\u308c\u307e\u3067\u8a00\u3063\u3066\u304d\u305f\u3053\u3068\u3092\u5909\u3048\u308b\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u5fc3\u81d3\u306b\u60aa\u3044\u3068\u3044\u3046\u306e\u306f\u3001\u3044\u307e\u3055\u3089\u8986\u3059\u3053\u3068\u304c\u96e3\u3057\u3044\u3067\u3057\u3087\u3046\u304b\u3089\u3001\u8fbb\u8904\u3092\u5408\u308f\u305b\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u304c\u4eca\u307b\u3069\u5e83\u304c\u308b\u524d\u306b\u3001\u3042\u308c\u307b\u3069\u30b1\u30c8\u30f3\u4f53\u306f\u6709\u5bb3\u3060\u3068\u8a00\u3063\u3066\u3044\u305f\u306e\u306b\u3001SGLT\u20102\u963b\u5bb3\u85ac\u304c\u30b1\u30c8\u30f3\u4f53\u3092\u5897\u52a0\u3055\u305b\u3001\u305d\u308c\u304c\u5fc3\u4fdd\u8b77\u3084\u814e\u4fdd\u8b77\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\uff08\u3053\u3053<\/a>\u3068\u3053\u3053<\/a>\u306a\u3069\u53c2\u7167\uff09\u3053\u3068\u304c\u308f\u304b\u308b\u3068\u3001\u30b1\u30c8\u30f3\u4f53\u3092\u60aa\u304f\u533b\u5e2b\u306f\u3044\u306a\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u624b\u306e\u3072\u3089\u3092\u304b\u3048\u3059\u3053\u3068\u306f\u7c21\u5358\u306a\u3088\u3046\u3067\u3059\u3002<\/p>\n

\u78ba\u304b\u306b\u3001SGLT\u20102\u963b\u5bb3\u85ac\u306b\u306f\u5229\u70b9\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u52b9\u679c\u306f\u7cd6\u8cea\u5236\u9650\u3092\u6a21\u5023\u3057\u305f\u4e00\u90e8\u306e\u52b9\u679c\u306b\u904e\u304e\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u3064\u307e\u308a\u3001\u4ed6\u306e\u3053\u308c\u307e\u3067\u306e\u7cd6\u5c3f\u75c5\u85ac\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001\u3044\u308d\u3044\u308d\u306a\u6709\u76ca\u6027\u306f\u8a8d\u3081\u3089\u308c\u307e\u3059\u304c\u3001\u7cd6\u8cea\u5236\u9650\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001\u305d\u306e\u52b9\u679c\u306f\u308f\u305a\u304b\u3067\u3059\u3002<\/p>\n

\u308f\u3056\u308f\u3056\u5fc3\u81d3\u3084\u814e\u81d3\u3092\u50b7\u3064\u3051\u308b\u3088\u3046\u306a\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3055\u305b\u3066\u3001\u4f59\u8a08\u306a\u7cd6\u8cea\u3092\u4f53\u306b\u5165\u308c\u3066\u3001\u305d\u308c\u3092\u7121\u7406\u3084\u308a\u304a\u3057\u3063\u3053\u3067\u51fa\u3059\u85ac\u3092\u98f2\u3080\u304f\u3089\u3044\u306a\u3089\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3057\u305f\u65b9\u304c\u4f55\u500d\u3082\u52b9\u679c\u7684\u3001\u5065\u5eb7\u7684\u3067\u3059\u3002<\/p>\n

\u300cClinical relevance between sodium-glucose co-transporter 2 inhibitors and lipid profiles in Asian patients with type 2 diabetes mellitus: a systematic review with a meta-analysis of randomized controlled trials\u300d<\/span><\/p>\n

\u300c\u30a2\u30b8\u30a2\u4eba2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30ca\u30c8\u30ea\u30a6\u30e0\u30fb\u30b0\u30eb\u30b3\u30fc\u30b9\u5171\u8f38\u9001\u4f532\u963b\u5bb3\u85ac\u3068\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306e\u81e8\u5e8a\u7684\u95a2\u9023\u6027\uff1a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308b\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

SGLT-2\u963b\u5bb3\u85ac\u306f\u3001\u73fe\u5728GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u4e26\u3093\u3067\u3001\u7cd6\u5c3f\u75c5\u306e\u85ac\u306e\u82b1\u5f62\uff08\u8868\u73fe\u304c\u53e4\u3044\uff1f\uff09\u3067\u3059\u3002\u3067\u306f\u3001\u305d\u306e\u5b9f\u529b\u3001\u305d\u306e\u5f71\u97ff\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002 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