{"id":33944,"date":"2026-04-17T09:00:22","date_gmt":"2026-04-17T00:00:22","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=33944"},"modified":"2026-04-17T09:00:22","modified_gmt":"2026-04-17T00:00:22","slug":"%e7%b3%96%e8%b3%aa%e5%88%b6%e9%99%90%e3%81%a7%e3%82%b1%e3%83%88%e3%83%bc%e3%82%b7%e3%82%b9%e3%81%ab%e3%81%aa%e3%81%a3%e3%81%a6%e3%81%84%e3%82%8b%e4%ba%ba%e3%81%8c%e7%b3%96%e8%b3%aa%e5%88%b6%e9%99%90-5","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=33944","title":{"rendered":"\u7cd6\u8cea\u5236\u9650\u3067\u30b1\u30c8\u30fc\u30b7\u30b9\u306b\u306a\u3063\u3066\u3044\u308b\u4eba\u304c\u7cd6\u8cea\u5236\u9650\u3092\u6b62\u3081\u305f\u3089\u3069\u3046\u306a\u308b\uff1f\u3000\u305d\u306e5"},"content":{"rendered":"

\u7cd6\u8cea\u5236\u9650\u3067\u30b1\u30c8\u30f3\u4f53\u304c\u5897\u52a0\u3059\u308b\u30b1\u30c8\u30fc\u30b7\u30b9\u3068\u3001\u7cd6\u8cea\u5236\u9650\u3092\u6b62\u3081\u3066\u307f\u305f\u3068\u304d\u306e\u69d8\u3005\u306a\u30d1\u30e9\u30e1\u30fc\u30bf\u306e\u52d5\u304d\u3092\u8ffd\u3046\u30b7\u30ea\u30fc\u30ba\u306e\u7d9a\u304d\u3067\u3059\u3002\uff08\u300c\u305d\u306e1<\/a>\u300d\u300c\u305d\u306e2<\/a>\u300d\u300c\u305d\u306e3<\/a>\u300d\u300c\u305d\u306e4<\/a>\u300d\u53c2\u7167\uff09<\/p>\n

\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3068\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u306f\u3001\u5973\u6027\u30db\u30eb\u30e2\u30f3\u8abf\u7bc0\u3068\u751f\u6b96\u5065\u5eb7\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u6027\u30db\u30eb\u30e2\u30f3\u7d50\u5408\u30b0\u30ed\u30d6\u30ea\u30f3\uff08SHBG\uff09\u306f\u3001\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3001\u809d\u6a5f\u80fd\u3001\u304a\u3088\u3073\u4ee3\u8b1d\u72b6\u614b\u306b\u3088\u3063\u3066\u6a5f\u80fd\u304c\u8abf\u7bc0\u3055\u308c\u308b\u91cd\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308a\u3001\u5faa\u74b0\u6027\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u6d3b\u6027\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3068\u7d30\u80de\u5185\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u5185\u5206\u6ccc\u304a\u3088\u3073\u751f\u6b96\u751f\u7406\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u6291\u5236\u3057\u305f\u5834\u5408\u306e\u5973\u6027\u306e\u751f\u6b96\u6a5f\u80fd\u304a\u3088\u3073\u5185\u5206\u6ccc\u6a5f\u80fd\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u8abf\u67fb\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5e73\u57473.9\u5e74\u306b\u308f\u305f\u308a\u6804\u990a\u6027\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u7dad\u6301\u3057\u3066\u304d\u305f\u3001\u75e9\u305b\u578b\uff08BMI 20.52\uff09\u3001\u5065\u5eb7\u306a\u9589\u7d4c\u524d\u5973\u602710\u540d\uff08\u5e73\u5747\u5e74\u9f6232.30 \u6b73\uff09\u304c\u5bfe\u8c61\u3067\u3059\u3002\u8a66\u9a13\u306f\u300121\u65e5\u9593\u306e\u6b63\u5e38\u30b1\u30c8\u30f3\u8840\u75c7\uff08P1\uff09\u3067\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30c7\u30fc\u30bf\u53ce\u96c6\u300121\u65e5\u9593\u306f\u7cd6\u8cea\u5236\u9650\u3092\u3084\u3081\u3066\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u6291\u5236\uff08P2\uff09\u3057\u3001\u305d\u3057\u306621\u65e5\u9593\u306e\u6b63\u5e38\u30b1\u30c8\u30f3\u8840\u75c7\uff08P3\uff09\u3078\u306e\u5fa9\u5e30\u3057\u307e\u3059\u3002\u98df\u4e8b\u5185\u5bb9\u306f\u3001\u4ee5\u524d\u306b\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u6700\u521d\u306e21\u65e5\u9593\uff08\u30d5\u30a7\u30fc\u30ba1\uff1aP1\uff09\u306f\u305a\u3063\u3068\u8d85\u4f4e\u70ad\u6c34\u5316\u7269\u9ad8\u8102\u80aa\u98df (VCHF) \u3067\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf\u306e\u5272\u5408\u3068\u3057\u3066\u3001\u70ad\u6c34\u5316\u72698\uff05\u3001\u30bf\u30f3\u30d1\u30af\u8cea17\uff05\u3001\u8102\u8cea75\uff05\u3067\u3057\u305f\u3002\u98df\u3079\u308b\u3082\u306e\u306f\u81ea\u7531\u3067\u3059\u3002\u70ad\u6c34\u5316\u72698\uff05\u306a\u306e\u3067\u3001\u30ac\u30c3\u30c4\u30ea\u7cd6\u8cea\u5236\u9650\u3067\u3059\u30021\u65e54\u56de\u8840\u7cd6\u5024\u3068\u30b1\u30c8\u30f3\u4f53\u5024\uff08\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178\u5024\uff09\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178\u5024\u30920.5mmol\/L\uff08\u65e5\u672c\u306e\u5358\u4f4d\u3067\u306f500\u03bcmol\/L\uff09\u3092\u7dad\u6301\u3057\u3066\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u4fdd\u3061\u307e\u3057\u305f\u3002<\/p>\n

21\u65e5\u9593\uff08\u30d5\u30a7\u30fc\u30ba2\uff1aP2\uff09\u3067\u306f\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u6291\u5236\u3059\u308b\u3088\u3046\u306a\u98df\u4e8b\u3092\u3057\u307e\u3059\u3002\u3064\u307e\u308a\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u3059\u3002\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178\u50240.3mmol\/L\u672a\u6e80\u304c\u76ee\u6a19\u3067\u3059\u30021\u65e5\u3042\u305f\u308a\u5c11\u306a\u304f\u3068\u3082267g\u306e\u70ad\u6c34\u5316\u7269\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3092\u63a8\u5968\u3057\u3001\u70ad\u6c34\u5316\u726955\uff05\u3001\u30bf\u30f3\u30d1\u30af\u8cea20\uff05\u3001\u8102\u8cea25\uff05\u3067\u81ea\u7531\u306b\u5c11\u306a\u304f\u3068\u30823\u56de\u306b\u5206\u3051\u3066\u98df\u4e8b\u3057\u307e\u3057\u305f\u3002<\/p>\n

21\u65e5\u9593\uff08\u30d5\u30a7\u30fc\u30ba\uff1aP3\uff09\u306fP1\u3068\u540c\u69d8\u306e\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u30d1\u30e9\u30e1\u30fc\u30bf<\/span><\/th>\nP1<\/span><\/th>\nP2<\/span><\/th>\nP3<\/span><\/th>\n<\/tr>\n<\/thead>\n
BMI<\/span>
\n\uff08kg\/m2\uff09<\/span><\/td>\n		20.52<\/span>
\n(\u00b1 1.39)<\/span><\/td>\n		21.54<\/span>
\n(\u00b1 1.29)<\/span><\/td>\n		20.82<\/span>
\n(\u00b1 1.46)<\/span><\/td>\n<\/tr>\n
\u4f53\u8102\u80aa\u91cf<\/span>
\n\uff08kg\uff09<\/span><\/td>\n		14.21<\/span>
\n(\u00b1 2.55)<\/span><\/td>\n		15.88<\/span>
\n(\u00b1 2.23)<\/span><\/td>\n		14.78<\/span>
\n(\u00b1 2.20)<\/span><\/td>\n<\/tr>\n
\u30a4\u30f3\u30b9\u30ea\u30f3<\/span>
\n\uff08\u03bcIU\/mL\uff09<\/span><\/td>\n		4.95<\/span>
\n(\u00b1 1.24)<\/span><\/td>\n		9.06<\/span>
\n(\u00b1 2.13)<\/span><\/td>\n		5.62<\/span>
\n(\u00b1 1.83)<\/span><\/td>\n<\/tr>\n
\u8840\u7cd6\u5024<\/span>
\n\uff08mmol\/L\uff09<\/span><\/td>\n		4.23<\/span>
\n(\u00b1 0.50)<\/span><\/td>\n		5.01<\/span>
\n(\u00b1 0.70)<\/span><\/td>\n		4.24<\/span>
\n(\u00b1 0.28)<\/span><\/td>\n<\/tr>\n
\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178<\/span>
\n\uff08mmol\/L\uff09<\/span><\/td>\n		2.43<\/span>
\n(\u00b1 1.28)<\/span><\/td>\n		0.18<\/span>
\n(\u00b1 0.13)<\/span><\/td>\n		2.31<\/span>
\n(\u00b1 0.71)<\/span><\/td>\n<\/tr>\n
HOMA-IR<\/span><\/td>\n0.93<\/span>
\n(\u00b1 0.26)<\/span><\/td>\n		2.03<\/span>
\n(\u00b1 0.65)<\/span><\/td>\n		1.07<\/span>
\n(\u00b1 0.40)<\/span><\/td>\n<\/tr>\n
GKI<\/span><\/td>\n2.23<\/span>
\n(\u00b1 1.20)<\/span><\/td>\n		49.68<\/span>
\n(\u00b1 42.62)<\/span><\/td>\n		1.99<\/span>
\n(\u00b1 0.60)<\/span><\/td>\n<\/tr>\n
IGF-1<\/span>
\n\uff08\u03bcg\/L\uff09<\/span><\/td>\n		149.30<\/span>
\n(\u00b1 32.96)<\/span><\/td>\n		273.40<\/span>
\n(\u00b1 85.66)<\/span><\/td>\n		136.90<\/span>
\n(\u00b1 39.60)<\/span><\/td>\n<\/tr>\n
\u30ec\u30d7\u30c1\u30f3<\/span>
\n\uff08ng\/mL\uff09<\/span><\/td>\n		4.50<\/span>
\n(\u00b1 3.66)<\/span><\/td>\n		15.08<\/span>
\n(\u00b1 8.00)<\/span><\/td>\n		4.57<\/span>
\n(\u00b1 3.48)<\/span><\/td>\n<\/tr>\n
GLP-1<\/span>
\n\uff08pg\/mL\uff09<\/span><\/td>\n		1,383.18<\/span>
\n(\u00b1 911.36)<\/span><\/td>\n		576.72<\/span>
\n(\u00b1 452.43)<\/span><\/td>\n		1,471.85<\/span>
\n(\u00b1 1,066.75)<\/span><\/td>\n<\/tr>\n
GGT<\/span>
\n\uff08U\/L\uff09<\/span><\/td>\n		9.60<\/span>
\n(\u00b13.13)<\/span><\/td>\n		12.40 (\u00b12.55)<\/span><\/td>\n9.70<\/span>
\n(\u00b12.50)<\/span><\/td>\n<\/tr>\n
\u30a2\u30c7\u30a3\u30dd\u30cd\u30af\u30c1\u30f3<\/span>
\n\uff08\u03bcg\/L\uff09<\/span><\/td>\n		9.08<\/span>
\n(\u00b1 4.18)<\/span><\/td>\n		10.75<\/span>
\n(\u00b1 6.76)<\/span><\/td>\n		8.70<\/span>
\n(\u00b1 3.25)<\/span><\/td>\n<\/tr>\n
TSH<\/span>
\n\uff08mIU\/L\uff09<\/span><\/td>\n		1.40<\/span>
\n(\u00b1 0.74)<\/span><\/td>\n		1.56<\/span>
\n(\u00b1 0.75)<\/span><\/td>\n		1.25<\/span>
\n(\u00b1 0.81)<\/span><\/td>\n<\/tr>\n
\u904a\u96e2T3<\/span>
\n\uff08pmol\/L\uff09<\/span><\/td>\n		3.82<\/span>
\n(\u00b1 0.28)<\/span><\/td>\n		5.50<\/span>
\n(\u00b1 0.72)<\/span><\/td>\n		4.05<\/span>
\n(\u00b1 0.54)<\/span><\/td>\n<\/tr>\n
\u30ea\u30d0\u30fc\u30b9T3<\/span>
\n\uff08nmol\/L\uff09<\/span><\/td>\n		0.29<\/span>
\n(\u00b1 0.09)<\/span><\/td>\n		0.26<\/span>
\n(\u00b1 0.10)<\/span><\/td>\n		0.25<\/span>
\n(\u00b1 0.09)<\/span><\/td>\n<\/tr>\n
T4<\/span>
\n\uff08pmol\/L\uff09<\/span><\/td>\n		13.52<\/span>
\n(\u00b1 1.61)<\/span><\/td>\n		13.24<\/span>
\n(\u00b1 1.49)<\/span><\/td>\n		12.65<\/span>
\n(\u00b1 0.66)<\/span><\/td>\n<\/tr>\n
\u9244<\/span>
\n\uff08\u03bcmol\/L\uff09<\/span><\/td>\n		16.62<\/span>
\n(\u00b1 7.27)<\/span><\/td>\n		14.40<\/span>
\n(\u00b1 8.70)<\/span><\/td>\n		11.76<\/span>
\n(\u00b1 11.78)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
<\/div>\n
\u30b1\u30c8\u30fc\u30b7\u30b9\u3092\u6291\u5236\u3001\u3064\u307e\u308a\u7cd6\u8cea\u5236\u9650\u3092\u3084\u3081\u308b\u3068\u3001BMI \u3001\u8102\u80aa\u91cf\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3001\u8840\u7cd6\u5024\u3001HOMA-IR\u3001GKI\u3001IGF- 1 \u3001\u30ec\u30d7\u30c1\u30f3\u3001GGT\u3001\u904a\u96e2 T3\u306f\u3069\u308c\u3082\u6709\u610f\u306b\u5897\u52a0\u3057\u307e\u3057\u305f\u3002HOMA-IR\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3084IGF- 1 \u306f2\u500d\u8fd1\u304f\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u306d\u3002<\/div>\n
\u03b2\u30d2\u30c9\u30ed\u30ad\u30b7\u916a\u9178<\/span>\u3001GLP-1\u306f\u5927\u304d\u304f\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3059\u3002GLP-1\u306a\u3093\u3066\u534a\u5206\u4ee5\u4e0b\u3067\u3059\u306d\u3002\u3060\u304b\u3089\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304c\u5fc5\u8981\u306b\u306a\u308b\u3093\u3067\u3057\u3087\u3046\u3002<\/div>\n
P3 \u4ee5\u964d\u306b\u307b\u3068\u3093\u3069\u306f\u9006\u8ee2\u3057\u307e\u3057\u305f\u3002<\/div>\n
<\/div>\n
\"\"<\/a><\/div>\n
\u4e0a\u306e\u56f3\u306e\u3088\u3046\u306b\u3001SHBG\u306fP1\u3067107.70 nmol\/L\u304b\u3089P2\u306772.53 nmol\/L\u306b\u6709\u610f\u306b\u6e1b\u5c11\u3057\u307e\u3057\u305f\u202f\u3002\u3053\u306e\u50be\u5411\u306fP3\u306e\u5f8c\u9006\u8ee2\u3057\u3001P3\u3067\u306f111.60 nmol\/L\u306b\u6709\u610f\u306b\u623b\u308a\u307e\u3057\u305f\u3002\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u3001LH\u3001FSH\u306e\u5909\u5316\u306f\u3001\u3053\u306e\u7814\u7a76\u3067\u306f\u7d71\u8a08\u7684\u306b\u6709\u610f\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/div>\n
<\/div>\n
<\/div>\n
\"\"<\/a><\/div>\n

\u4e0a\u306e\u56f3\u306f\u3001\u500b\u4eba\u306eSHBG\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u304a\u3088\u3073HOMA-IR\u306e\u5909\u5316\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u3001HOMA-IR\u3068SHBG\u306e\u9593\u306b\u306f\u6709\u610f\u306a\u9006\u76f8\u95a2\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u3001\u500b\u4eba\u306eSHBG\u3068GLP-1\u306e\u5909\u5316\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u4e00\u4eba\u3060\u3051\u5909\u306a\u52d5\u304d\u3092\u3057\u3066\u3044\u307e\u3059\u304c\u3001SHBG\u3068GLP-1\u306f\u6709\u610f\u306a\u76f8\u95a2\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5973\u6027\u306e\u751f\u6b96\u5668\u7cfb\u306f\u3001\u6804\u990a\u72b6\u614b\u3068\u5168\u4f53\u7684\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u30d0\u30e9\u30f3\u30b9\u306b\u3088\u3063\u3066\u53b3\u5bc6\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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\u300cKetosis suppression and ageing (KetoSAge): the effect of suppressing ketosis on SHBG and sex hormone profiles in healthy premenopausal women, and its implications for cancer risk and therapy\u300d<\/span><\/p>\n

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