{"id":34690,"date":"2026-07-02T08:31:36","date_gmt":"2026-07-01T23:31:36","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=34690"},"modified":"2026-07-02T08:31:36","modified_gmt":"2026-07-01T23:31:36","slug":"ldl%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%8c%e9%95%b7%e6%9c%9f%e9%96%93%e4%bd%8e%e3%81%84%e3%81%a8%e8%84%b3%e3%81%ae%e5%ae%8c%e5%85%a8%e6%80%a7%e3%81%8c%e4%bd%8e","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=34690","title":{"rendered":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9577\u671f\u9593\u4f4e\u3044\u3068\u8133\u306e\u5b8c\u5168\u6027\u304c\u4f4e\u4e0b\u3059\u308b"},"content":{"rendered":"<p>\u4e00\u822c\u306e\u4eba\u3067\u3082\u3001\u533b\u5e2b\u306e\u4e2d\u3067\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u4f4e\u3051\u308c\u3070\u4f4e\u3044\u307b\u3069\u826f\u3044\u3068\u601d\u3063\u3066\u3044\u308b\u4eba\u304c\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4eba\u9593\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u91cd\u8981\u306a\u3082\u306e\u3067\u3059\u3002\u8133\u306f\u6c34\u5206\u3092\u9664\u304f\u3068\u305d\u306e\u7d0460\u301c65\uff05\u304c\u8102\u8cea\u3067\u3067\u304d\u3066\u3044\u3066\u3001\u8133\u306e\u5168\u8102\u8cea\u306e\u7d0420\u301c30\uff05\u3092\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5360\u3081\u3066\u3044\u307e\u3059\u3002\u5168\u8eab\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u7d0425\uff05\u304c\u8133\u306b\u5b58\u5728\u3057\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u3068\u8133\u306b\u60aa\u305d\u3046\u3067\u3059\u306d\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u4f4e\u3044\u3053\u3068\u3078\u306e\u9577\u671f\u66dd\u9732\u3068\u8133\u306e\u69cb\u9020\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u8abf\u67fb\u3057\u3066\u3044\u307e\u3059\u3002\u5fc3\u8840\u7ba1\u75be\u60a3\u3001\u8133\u5352\u4e2d\u3001\u8a8d\u77e5\u75c7\u3001\u307e\u305f\u306f\u795e\u7d4c\u7cbe\u795e\u75be\u60a3\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u3066\u3044\u306a\u3044987\u4eba\uff08\u5e74\u9f62\u4e2d\u592e\u502455\u6b73\uff09\u304c\u5bfe\u8c61\u3067\u3059\u300212\u5e74\u9593\u306b\u308f\u305f\u308b\u9577\u671f\u8ffd\u8de1\u8abf\u67fb\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002MRI\u691c\u67fb\u3067\u8133\u767d\u8cea\u306e\u5fae\u7d30\u69cb\u9020\u306e\u7279\u5fb4\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"34705\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=34705\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?fit=1772%2C1846&amp;ssl=1\" data-orig-size=\"1772,1846\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u8133LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30ebOriginal.00029330-990000000-02073.F1\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?fit=640%2C667&amp;ssl=1\" class=\"alignnone wp-image-34705 size-large\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=640%2C667\" alt=\"\" width=\"640\" height=\"667\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=983%2C1024&amp;ssl=1 983w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=288%2C300&amp;ssl=1 288w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=768%2C800&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=1474%2C1536&amp;ssl=1 1474w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?resize=1170%2C1219&amp;ssl=1 1170w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?w=1772&amp;ssl=1 1772w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/971739aa539ed79db4d2af54bfa696b2.jpeg?w=1280 1280w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u3001fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD)\u3001\u65e5\u672c\u8a9e\u306b\u3059\u308b\u3068\u3001\u5206\u6570\u7570\u65b9\u6027 (FA)\u3001\u5e73\u5747\u62e1\u6563\u7387 (MD)\u3001\u8ef8\u65b9\u5411\u62e1\u6563\u7387 (AD)\u3001\u534a\u5f84\u65b9\u5411\u62e1\u6563\u7387 (RD) \u3068\u3044\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u96e3\u3057\u3044\u3053\u3068\u306f\u7f6e\u3044\u3066\u304a\u3044\u3066\u3001\u4e00\u822c\u7684\u306b\u3001FA\u5024\u304c\u4f4e\u304f\u3001MD\u3001AD\u3001RD\u5024\u304c\u9ad8\u3044\u307b\u3069\u3001\u8133\u767d\u8cea\u306e\u5fae\u7d30\u69cb\u9020\u306e\u5b8c\u5168\u6027\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002\u6a2a\u8ef8\u306f12\u5e74\u9593\u306e\u5e73\u5747\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3067\u3059\u3002\u305d\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c100\uff5e130mg\/dL\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u3001\u305d\u308c\u3088\u308a\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u304f\u306a\u308b\u307b\u3069\u3001FA\u5024\u304c\u4f4e\u304f\u3001MD\u3001AD\u3001RD\u5024\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u308b\u306e\u304c\u308f\u304b\u308a\u307e\u3059\u3002\u3064\u307e\u308aLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u307b\u3069\u3001\u8133\u767d\u8cea\u306e\u5fae\u7d30\u69cb\u9020\u306e\u5b8c\u5168\u6027\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u95a2\u9023\u6027\u306f\u3001\u7537\u6027\u304a\u3088\u307350\u6b73\u4ee5\u4e0a\u306e\u4eba\u306b\u304a\u3044\u3066\u7279\u306b\u9855\u8457\u3067\u3057\u305f\u3002<\/p>\n<p>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u4eba\u306f\u3001\u8133\u306e\u5065\u5eb7\u3092\u640d\u306a\u3046\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=31623\" target=\"_blank\" rel=\"noopener\">\u865a\u8840\u6027\u8133\u5352\u4e2d\u3067\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u65b9\u304c\u8a8d\u77e5\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3059\u308b<\/a>\u300d\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=6269\" target=\"_blank\" rel=\"noopener\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u4f4e\u3044<\/a>\u300d\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u65b9\u304c\u8a8d\u77e5\u6a5f\u80fd\u306b\u306f\u6709\u5229\u306a\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u305d\u308c\u3067\u3082\u3042\u306a\u305f\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3092\u4f4e\u304f\u3057\u305f\u3044\u3067\u3059\u304b\uff1f<\/p>\n<p>\u8a8d\u77e5\u75c7\u306f\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u3067\u3059\u3002<\/p>\n<p><span style=\"color: #3366ff;\">\u300cAssociation of long-term exposure to lower low-density lipoprotein cholesterol with neuroimaging metrics: A population-based cohort study\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u4f4e\u5bc6\u5ea6\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u9577\u671f\u66dd\u9732\u3068\u795e\u7d4c\u753b\u50cf\u6307\u6a19\u3068\u306e\u95a2\u9023\uff1a\u96c6\u56e3\u30d9\u30fc\u30b9\u306e\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/journals.lww.com\/cmj\/fulltext\/9900\/association_of_long_term_exposure_to_lower.2073.aspx\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e00\u822c\u306e\u4eba\u3067\u3082\u3001\u533b\u5e2b\u306e\u4e2d\u3067\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u4f4e\u3051\u308c\u3070\u4f4e\u3044\u307b\u3069\u826f\u3044\u3068\u601d\u3063\u3066\u3044\u308b\u4eba\u304c\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4eba\u9593\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u91cd\u8981\u306a\u3082\u306e\u3067\u3059\u3002\u8133\u306f\u6c34\u5206\u3092\u9664\u304f\u3068\u305d\u306e\u7d0460\u301c65\uff05\u304c\u8102\u8cea\u3067\u3067\u304d\u3066\u3044\u3066\u3001\u8133\u306e\u5168\u8102\u8cea\u306e\u7d0420\u301c3<\/p>\n","protected":false},"author":1,"featured_media":34704,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[145,111,155,5,144],"tags":[24,36,98],"class_list":["post-34690","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ldl","category-111","category-cvd","category-5","category-cholesterol","tag-cholesterol","tag-dementia","tag-98","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2026\/07\/32960120_s.jpg?fit=640%2C498&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-91w","jetpack-related-posts":[{"id":6269,"url":"https:\/\/promea2014.com\/blog\/?p=6269","url_meta":{"origin":34690,"position":0},"title":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u4f4e\u3044","author":"Dr.Shimizu","date":"2018\u5e7411\u670813\u65e5","format":false,"excerpt":"\u8a8d\u77e5\u75c7\u306f\u3069\u3093\u3069\u3093\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f3\u578b\u7cd6\u5c3f\u75c5\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u8840\u7cd6\u5024\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/4e3778eeb02c48c57fbb66f8b9f550f9_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/4e3778eeb02c48c57fbb66f8b9f550f9_s.jpg?fit=640%2C427&ssl=1&resize=350%2C200 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