{"id":35808,"date":"2026-09-11T09:03:27","date_gmt":"2026-09-11T00:03:27","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=35808"},"modified":"2026-09-11T09:03:27","modified_gmt":"2026-09-11T00:03:27","slug":"%e7%b3%96%e8%b3%aa%e5%88%b6%e9%99%90%e3%81%a7ldl%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%a0%e3%81%91%e3%81%a7%e3%81%aa%e3%81%8fhdl%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=35808","title":{"rendered":"\u7cd6\u8cea\u5236\u9650\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3060\u3051\u3067\u306a\u304fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u7206\u5897\u3000\u79c1\u306fCETP\u6b20\u640d\u75c7\u306a\u306e\u304b\uff1f"},"content":{"rendered":"<p>\u5c02\u9580\u5bb6\u3068\u3044\u3046\u306e\u306f\u3001\u81ea\u5206\u306e\u77e5\u3063\u3066\u3044\u308b\u77e5\u8b58\u306e\u4e2d\u3067\u7269\u4e8b\u3092\u8aac\u660e\u3057\u3088\u3046\u3068\u3057\u307e\u3059\u3002\u81ea\u5206\u306e\u77e5\u8b58\u304c\u9593\u9055\u3063\u3066\u3044\u308b\u3068\u304b\u3001\u81ea\u5206\u306e\u77e5\u3063\u3066\u308b\u77e5\u8b58\u3067\u306f\u8aac\u660e\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u3042\u308b\u306a\u3069\u3068\u306f\u3042\u307e\u308a\u8003\u3048\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u533b\u5b66\u90e8\u3067\u7fd2\u3063\u305f\u3053\u3068\u304c\u6b63\u3057\u3044\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u6559\u79d1\u66f8\u306b\u66f8\u3044\u3066\u3042\u308b\u3053\u3068\u304c\u6b63\u3057\u3044\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u307e\u3057\u3066\u3084\u5229\u76ca\u76f8\u53cd\u306e\u3042\u308b\u5b66\u4f1a\u3067\u5f97\u305f\u77e5\u8b58\u304c\u6b63\u3057\u3044\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u6211\u3005\u306f\u307e\u3060\u307e\u3060\u7121\u77e5\u3067\u3001\u77e5\u3089\u306a\u3044\u3053\u3068\u3070\u304b\u308a\u306a\u3093\u3067\u3059\u3002<\/p>\n<p>\u79c1\u306e\u3042\u308b\u65e5\u306e\u8102\u8cea\u306e\u30c7\u30fc\u30bf\u306f\u6b21\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3000389mg\/dL<br \/>\nLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3000254mg\/dL<br \/>\nHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3000118mg\/dL<\/p>\n<p>\u3055\u3042\u3001\u3053\u308c\u3092\u898b\u305f\u3068\u304d\u306b\u5c02\u9580\u5bb6\u306f\u4f55\u3068\u601d\u3046\u3067\u3057\u3087\u3046\u304b\uff1f<br \/>\nLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3059\u304e\u308b\uff01\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\uff08FH\uff09\u306a\u3093\u3058\u3083\u306a\u3044\u304b\uff1f<br \/>\nHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3059\u304e\u308b\uff01CETP\u6b20\u640d\u75c7\u306a\u3093\u3058\u3083\u306a\u3044\u304b\uff1f<br \/>\nLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u306e\u306f\u3082\u3061\u308d\u3093\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3060\u3063\u3066\u975e\u5e38\u306b\u9ad8\u3044\u306e\u306f\u5371\u967a\u3060\uff01<\/p>\n<p>\u3053\u306e\u30c7\u30fc\u30bf\u306f\u3042\u308b\u65e5\u3001\u3042\u308b\u6642\u306e\u30c7\u30fc\u30bf\u306b\u3059\u304e\u307e\u305b\u3093\u3002\u79c1\u304c\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u524d\u306f\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3082\u3063\u3068\u4f4e\u304f\u3001\u6b63\u5e38\u7bc4\u56f2\u5185\u306b\u53ce\u307e\u3063\u3066\u3044\u305f\u9803\u3082\u3042\u308a\u307e\u3059\u3002FH\u3067\u3042\u308c\u3070\u3001\u82e5\u3044\u6642\u304b\u3089\u305a\u3063\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u306f\u305a\u3067\u3057\u3087\u3046\u3002\u3082\u3061\u308d\u3093\u907a\u4f1d\u5b50\u691c\u67fb\u307e\u3067\u306f\u3057\u3066\u3044\u307e\u305b\u3093\u304c\u3002<\/p>\n<p>\u5f53\u7136HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u6642\u4ee3\u306f\u304b\u306a\u308a\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002CETP\u6b20\u640d\u75c7\u3067\u3042\u308c\u3070\u3001\u82e5\u3044\u6642\u304b\u3089\u305a\u3063\u3068HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u306f\u305a\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3068\u3001\u5c11\u306a\u304f\u306a\u3044\u5272\u5408\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u304f\u306a\u308a\u3001\u79c1\u306e\u3088\u3046\u306b\u3001\u3055\u3089\u306b\u306f\u3082\u3063\u3068\u7206\u767a\u7684\u306b\u9ad8\u304f\u306a\u308b\u4eba\u3082\u3044\u307e\u3059\u3002\u540c\u69d8\u306bHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u79c1\u306e\u3088\u3046\u306b\u7206\u5897\u3059\u308b\u4eba\u3082\u3044\u307e\u3059\u3002<\/p>\n<p>\u533b\u5e2b\u306f\u30c7\u30fc\u30bf\u3092\u898b\u3066\u3082\u3001\u98df\u4e8b\u306b\u3064\u3044\u3066\u306f\u4f55\u3082\u805e\u304b\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u7cd6\u8cea\u5236\u9650\u524d\u306e\u30c7\u30fc\u30bf\u306a\u3093\u3066\u77e5\u308b\u8a33\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u6050\u3089\u304f\u307b\u3068\u3093\u3069\u306e\u533b\u5e2b\u306f\u7cd6\u8cea\u5236\u9650\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3060\u3051\u3067\u306a\u304fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3082\u5927\u304d\u304f\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u306a\u3093\u3066\u77e5\u3089\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u3055\u3066\u3001\u305d\u308c\u3067\u3082\u79c1\u306fCETP\u6b20\u640d\u75c7\u3067\u3042\u308b\u53ef\u80fd\u6027\u306f\u5426\u5b9a\u3067\u304d\u307e\u305b\u3093\u3002\u3058\u3083\u3042\u3001\u8abf\u3079\u3066\u307f\u3088\u3046\uff01\u3068\u601d\u3044\u3001\u691c\u67fb\u3057\u3066\u307f\u307e\u3057\u305f\u3002\u6700\u8fd1\u3001\u8a66\u85ac\u306e\u9ad8\u9a30\u3084\u3001\u30cb\u30fc\u30ba\u306e\u554f\u984c\u306a\u306e\u304b\u3001\u69d8\u3005\u306a\u691c\u67fb\u304c\u4e2d\u6b62\u306b\u8ffd\u3044\u8fbc\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306eCETP\u3082\u4eca\u6708\u304b\u3089\u6e2c\u5b9a\u3067\u304d\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002\u306a\u3093\u3068\u304b\u9593\u306b\u5408\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u3068\u3053\u308d\u3067\u3001CETP\u304a\u3088\u3073CETP\u6b20\u640d\u75c7\u3063\u3066\u4f55\uff1f\u3068\u3044\u3046\u4eba\u3082\u3044\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>HDL\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u56de\u53ce\u3057\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u9006\u8f38\u9001\uff08reverse cholesterol transport, RCT\uff09\u3068\u3044\u3063\u3066\u3001\u672b\u68a2\u7d44\u7e54\u304b\u3089\u809d\u81d3\u3078\u904e\u5270\u306a\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u623b\u3059\u3053\u3068\u3067\u3001\u52d5\u8108\u786c\u5316\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u304c\u3044\u308f\u3086\u308b\u300c\u5584\u7389\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u300d\u305f\u308b\u6240\u4ee5\u3067\u3059\u3002<\/p>\n<p>CETP\u306fHDL\u304c\u56de\u53ce\u3057\u305f\u30b3\u30ec\u30b9\u30c6\u30ea\u30eb\u30a8\u30b9\u30c6\u30eb\uff08CE\uff09\u3092LDL\u3084VLDL\u306b\u8ee2\u9001\u3059\u308b\u5f79\u5272\u304c\u3042\u308a\u307e\u3059\u3002CETP\u304c\u5927\u304d\u304f\u6e1b\u5c11\u3057\u305f\u308a\u3001\u305d\u306e\u6a5f\u80fd\u304c\u5931\u308f\u308c\u308b\u3068HDL\u304c\u3059\u3054\u304f\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u98f2\u9152\u3067HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u304f\u306a\u308b\u306e\u306f\u3001\u3053\u306eCETP\u304c\u6e1b\u5c11\u3059\u308b\u304b\u3089\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>CETP\u6b20\u640d\u75c7\u306f\u3001\u6b27\u7c73\u3067\u306f\u975e\u5e38\u306b\u307e\u308c\u3067\u3001\u65e5\u672c\u306b\u304a\u3044\u3066\u6700\u3082\u9ad8\u983b\u5ea6\u306b\u898b\u3089\u308c\u3001\u65e5\u672c\u56fa\u6709\u306e\u30ea\u30dd\u86cb\u767d\u4ee3\u8b1d\u7570\u5e38\u75c7\u3068\u3082\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8457\u3057\u3044\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3092\u3068\u308b\u306b\u3082\u95a2\u308f\u3089\u305a\u52d5\u8108\u786c\u5316\u75c7\u304c\u9032\u884c\u3059\u308b\u3068\u3082\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.fpa.or.jp\/johocenter\/yakuji-main\/_1635.html?blockId=40186&amp;dbMode=article\" target=\"_blank\" rel=\"noopener\">\u3053\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8<\/a>\u306b\u3088\u308b\u3068\u3001\u300c<span style=\"color: #3366ff;\">\u308f\u304c\u56fd\u306e\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3067\u306f\u3001CETP\u6b20\u640d\u75c7\u306e\u983b\u5ea6\u304c\u9ad8\u304f\uff087\u5272\uff5e7\u52725\u5206\uff09\u3001CETP\u6b20\u640d\u75c7\u30db\u30e2\u63a5\u5408\u4f53\u3067\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c150\uff5e250mg\/dL\u3001\u30d8\u30c6\u30ed\u63a5\u5408\u4f53\u3067\u306f50\uff5e150mg\/dL\u3092\u5448\u3059\u308b\uff08\u57fa\u6e96\u5024\uff1a\u7537\u602740\uff5e85mg\/dL\u3001\u5973\u602740\uff5e95mg\/dL\uff09\u3002HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u6297\u52d5\u8108\u786c\u5316\u4f5c\u7528\u3092\u6709\u3059\u308b\u304c\u3001CETP\u6b20\u640d\u75c7\u306e\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3067\u306f\u3001\u9006\u306b\u52d5\u8108\u786c\u5316\u6027\u75be\u60a3\u4fdd\u6709\u7387\u304c\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/span>\u300d\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u5b9f\u969b\u306b\u3001\u79cb\u7530\u770c\u306fCETP\u6b20\u640d\u75c7\u304c\u96c6\u7a4d\u3059\u308b\u5730\u57df\u304c\u3042\u308b\u3088\u3046\u3067\u3059\u3002\u305d\u306e\u5730\u57df\u3092\u542b\u3080\u79cb\u7530\u770c\u5927\u4ed9\u5e02\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8abf\u67fb\u3067\u306f\u3001CETP\u6b20\u640d\u306b\u8d77\u56e0\u3059\u308b\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u4f8b\u306b\u304a\u3044\u3066\u3001CETP\u6b20\u640d\u306b\u8d77\u56e0\u3057\u306a\u3044\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u4f8b\u3088\u308a\u3001\u5fc3\u75be\u60a3\u3001\u8133\u5352\u4e2d\u306e\u6709\u75c5\u7387\u304c\u9ad8\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\uff08<a href=\"https:\/\/mhlw-grants.niph.go.jp\/project\/17257\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u3053\u306e\u75ab\u5b66\u7814\u7a76\u3067\u3001\u5354\u529b\u306e\u5f97\u3089\u308c\u305f\u4f4f\u6c11 181\u4eba\u4e2d\uff08\u5e73\u5747\u5e74\u9f62:\u7537\u6027 71\u624d\u3001\u5973\u6027 61 \u624d)\u3001CETP\u6b20\u640d\u75c7\u306f71\u4eba\u3001\u975eCETP \u6b20\u640d\u75c7\u306f\u3001110\u4eba\u3067\u3057\u305f\u3002\u53c2\u52a0\u4f4f\u6c11\u5168\u4f53\u306e\u5fc3\u75be\u60a3\u3001\u8133\u5352\u4e2d\u306e\u6709\u75c5\u7387\u306f\u3001\u305d\u308c\u305e\u308c 6.6%\uff0812\u4f8b\uff09\u30015.5%\uff089\u4f8b\uff09\u3067\u3057\u305f\u3002CETP\u6b20\u640d\u75c7\u3001\u975eCETP\u6b20\u640d\u75c7\u306e2\u7fa4\u306b\u5206\u3051\u3066\u691c\u8a0e\u3059\u308b\u3068\u3001CETP\u6b20\u640d\u75c7\u3067\u306f\u3001\u5fc3\u75be\u60a3\u3001\u8133\u5352\u4e2d\u306e\u6709\u75c5\u7387\u306f\u3001\u305d\u308c\u305e\u308c 11.3%\u30017.0%\u3001\u975eCETP\u6b20\u640d\u75c7\u3067\u306f\u3001\u305d\u308c\u305e\u308c\u30013.6%\u30013.6%\u3067\u3042\u308a\u3001\u5fc3\u75be\u60a3\u3001\u8133\u5352\u4e2d\u306e\u3044\u305a\u308c\u3082CETP\u6b20\u640d\u75c7\u3067\u3001\u975eCETP\u6b20\u640d\u75c7\u3088\u308a\u6709\u75c5\u7387\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u3001CETP\u6b20\u640d\u75c7\u7fa4\u3067\u4f4e\u5024\u306e\u50be\u5411\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u79c1\u306f\u3072\u3087\u3063\u3068\u3057\u305f\u3089CETP\u6b20\u640d\u75c7\u306e\u30d8\u30c6\u30ed\u63a5\u5408\u4f53\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u305d\u3046\u3059\u308b\u3068\u4e0a\u306e\u7814\u7a76\u306e\u3088\u3046\u306b\u3001\u3082\u3057\u304b\u3057\u305f\u3089\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u3067\u3082\u5909\u3067\u3059\u3002\u4e0a\u306e\u7814\u7a76\u3067\u306f\u3001CETP\u6b20\u640d\u75c7\u3067\u306fLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u4f4e\u5024\u306e\u50be\u5411\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002CETP\u304c\u50cd\u304b\u306a\u3051\u308c\u3070\u3001HDL\u304b\u3089LDL\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u8ee2\u9001\u3055\u308c\u307e\u305b\u3093\u304b\u3089\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u4f4e\u304f\u306a\u308b\u306f\u305a\u3067\u3059\u3002\u3067\u3082\u79c1\u306f\u975e\u5e38\u306b\u9ad8\u3044LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3067\u3059\u3002<\/p>\n<p>\u4ed6\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u3053\u3068\u3082\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08<a href=\"https:\/\/www.jmedj.co.jp\/blogs\/product\/product_14266\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p><span style=\"color: #3366ff;\">\u3010CETP\u6b20\u640d\u75c7\u3011<\/span><br \/>\n<span style=\"color: #3366ff;\">CETP\u306fHDL\u304b\u3089\u30a2\u30ddB\u542b\u6709\u30ea\u30dd\u86cb\u767d\u3078\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30a8\u30b9\u30c6\u30eb\uff08cholesterol ester\uff1aCE\uff09\u306e\u8ee2\u9001\u304a\u3088\u3073\u9006\u65b9\u5411\u3078\u306e\u30c8\u30ea\u30b0\u30ea\u30bb\u30e9\u30a4\u30c9\uff08triglyceride\uff1aTG\uff09\u306e\u8ee2\u9001\u304c\u963b\u5bb3\u3055\u308c\u308b\u305f\u3081\uff0c\u9ad8HDL-C\u8840\u75c7\u30fb\u4f4eLDL-C\u8840\u75c7\u3092\u5448\u3059\u308b\u3002HDL\u306bCE\u304c\u84c4\u7a4d\u3057\u3066\u901a\u5e38\u306f\u8a8d\u3081\u306a\u3044\u5927\u578b\u306eHDL\uff08HDL1\uff09\u304c\u51fa\u73fe\u3057\uff0cTG\u306b\u5bcc\u3093\u3067\u7c92\u5b50\u30b5\u30a4\u30ba\u304c\u591a\u69d8\u5316\u3059\u308b\u3002CETP\u6b20\u640d\u75c7\u30db\u30e2\u63a5\u5408\u4f53\u306eHDL-C\u6fc3\u5ea6\u306f\uff0c\u5065\u5e38\u8005\u306e3\uff5e4\u500d\u3068\u8457\u660e\u9ad8\u5024\u3068\u306a\u308b\u3002HDL\u306e\u69cb\u6210\u30a2\u30dd\u86cb\u767d\u306e\u4e2d\u3067Apo A-\u2160\u306f\u7d042\u500d\u306b\u5897\u52a0\u3057\uff0cApo A-\u2161\u306f\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u7a0b\u5ea6\u306e\u5897\u52a0\u306b\u3068\u3069\u307e\u308b\u3002LDL-C\u306f\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u4f4e\u4e0b\u3057\uff0cApo C-\u2161\uff0cApo C-\u2162\uff0cApo E\u304c\u3044\u305a\u308c\u30822\u500d\u4ee5\u4e0a\u306b\u5897\u52a0\u3059\u308b\u3002<\/span><\/p>\n<p>\u3053\u3053\u306b\u3082LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u4f4e\u4e0b\u3059\u308b\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002CETP\u6b20\u640d\u75c7\u306f\u9ad8HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30fb\u4f4eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u306f\u305a\u3067\u3059\u3002<\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001CETP\u6b20\u640d\u75c7\u306b\u3064\u3044\u3066\u3001\u3044\u308d\u3044\u308d\u6e2c\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<table tabindex=\"0\" data-figureviewer-ignore=\"true\">\n<thead>\n<tr class=\"rowsep\" data-xml-valign=\"top\">\n<th data-xml-align=\"left\" data-xml-valign=\"bottom\"><\/th>\n<th data-xml-valign=\"bottom\"><span dir=\"auto\">\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb<\/span><\/th>\n<th data-xml-valign=\"bottom\"><span dir=\"auto\">\u30d8\u30c6\u30ed\u63a5\u5408\u4f53<\/span><\/th>\n<th data-xml-valign=\"bottom\"><span dir=\"auto\">\u8907\u5408<\/span><br \/>\n<span dir=\"auto\">\u30d8\u30c6\u30ed\u63a5\u5408\u4f53<\/span><\/th>\n<th data-xml-valign=\"bottom\"><span dir=\"auto\">\u30db\u30e2\u63a5\u5408\u4f53<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">CETP\uff08\u03bcg\/ml\uff09<\/span><\/td>\n<td><span dir=\"auto\">1.24 \u00b1 0.4<\/span><\/td>\n<td><span dir=\"auto\">0.87 \u00b1 0.2<\/span><\/td>\n<td><span dir=\"auto\">0.46 \u00b1 0.2<\/span><\/td>\n<td><span dir=\"auto\">&lt;0.1<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/span><\/td>\n<td><span dir=\"auto\">195 \u00b1 36<\/span><\/td>\n<td><span dir=\"auto\">180 \u00b1 22<\/span><\/td>\n<td><span dir=\"auto\">261 \u00b1 29<\/span><\/td>\n<td><span dir=\"auto\">280 \u00b1 35<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/span><\/td>\n<td><span dir=\"auto\">120 \u00b1 31<\/span><\/td>\n<td><span dir=\"auto\">77 \u00b1 13<\/span><\/td>\n<td><span dir=\"auto\">102 \u00b1 29<\/span><\/td>\n<td><span dir=\"auto\">102 \u00b1 25<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/span><\/td>\n<td><span dir=\"auto\">52 \u00b1 14<\/span><\/td>\n<td><span dir=\"auto\">85 \u00b1 26<\/span><\/td>\n<td><span dir=\"auto\">139 \u00b1 22<\/span><\/td>\n<td><span dir=\"auto\">157 \u00b1 29<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">\u4e2d\u6027\u8102\u80aa<\/span><\/td>\n<td><span dir=\"auto\">120 \u00b1 70<\/span><\/td>\n<td><span dir=\"auto\">88 \u00b1 40<\/span><\/td>\n<td><span dir=\"auto\">101 \u00b1 52<\/span><\/td>\n<td><span dir=\"auto\">104 \u00b1 37<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">apoA-I<\/span><\/td>\n<td><span dir=\"auto\">144 \u00b1 29<\/span><\/td>\n<td><span dir=\"auto\">154 \u00b1 26<\/span><\/td>\n<td><span dir=\"auto\">224 \u00b1 41<\/span><\/td>\n<td><span dir=\"auto\">252 \u00b1 25<\/span><\/td>\n<\/tr>\n<tr data-xml-align=\"center\">\n<td data-xml-align=\"left\"><span dir=\"auto\">apoA-II<\/span><\/td>\n<td><span dir=\"auto\">35 \u00b1 5<\/span><\/td>\n<td><span dir=\"auto\">35 \u00b1 2<\/span><\/td>\n<td><span dir=\"auto\">42 \u00b1 10<\/span><\/td>\n<td><span dir=\"auto\">40 \u00b1 6<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4e0a\u306e\u8868\u306b\u793a\u3059\u3088\u3046\u306b\u3001<span dir=\"auto\">CETP\u306f\u30db\u30e2\u63a5\u5408\u4f53\u3067\u306f\u307b\u307c\u30bc\u30ed\u3067\u3059\u3002\u30d8\u30c6\u30ed\u63a5\u5408\u4f53\u3067\u30820.87\u03bcg\/ml\u3068\u4f4e\u5024\u3067\u3059\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306f1.24\u03bcg\/ml\u306a\u306e\u3067\u300130%\u307b\u3069\u5c11\u306a\u3044\u5024\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>\u691c\u67fb\u6a5f\u95a2\u306b\u3088\u3063\u3066CETP\u306e\u57fa\u6e96\u5024\u306f\u3042\u308b\u7a0b\u5ea6\u7570\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u79c1\u306e\u6301\u3063\u3066\u3044\u308b\u691c\u67fb\u6a5f\u95a2\u306e\u57fa\u6e96\u5024\u306f\u3001\u53c2\u8003\u5024\u3067\u3059\u304c\u3001\u7537\u6027\u30670.8\uff5e3.0<span dir=\"auto\">\u03bcg\/ml\u3001\u5973\u6027\u30671.5\uff5e3.4\u03bcg\/ml\u3067\u3059\u3002<\/span><\/p>\n<p>\u3055\u3089\u306b\u4ed6\u306e\u8ad6\u6587\u3082\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9565327\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\u3001\u56f3\u3082\u3053\u3053\u3088\u308a\uff09<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3.png\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"35863\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=35863\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3.png\" data-orig-size=\"480,414\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"CETP\u6b20\u640d\u75c7\u6d3b\u6027\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3.png\" class=\"alignnone size-full wp-image-35863\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3.png\" alt=\"\" width=\"480\" height=\"414\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3.png 480w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/40b6bc51347980eb7600b7e077c9eff3-300x259.png 300w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306fCETP\u5024\u3068CETP\u306e\u6d3b\u6027\u3067\u3059\u3002CETP\u5024\u304c\u9ad8\u3044\u307b\u3069\u6d3b\u6027\u3082\u9ad8\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df.png\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"35862\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=35862\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df.png\" data-orig-size=\"616,538\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"CETP\u6b20\u640d\u75c7\u5e73\u5747\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df.png\" class=\"alignnone size-full wp-image-35862\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df.png\" alt=\"\" width=\"616\" height=\"538\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df.png 616w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/919e77c7c9983f05844db815fb0676df-300x262.png 300w\" sizes=\"auto, (max-width: 616px) 100vw, 616px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u3001\u5de6\u304b\u3089CETP\u6b20\u640d\u75c7\u306e\u30db\u30e2\u63a5\u5408\u4f53\u3001\u6b21\u306e\u4e8c\u3064\u304c\u30d8\u30c6\u30ed\u63a5\u5408\u4f53\u3001\u6b21\u304c\u7537\u6027\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u4e00\u756a\u53f3\u304c\u5973\u6027\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306eCETP\u5024\u3067\u3059\u3002\u30db\u30e2\u63a5\u5408\u4f53\u306fCETP\u5024\u30bc\u30ed\u3067\u3059\u3002\u30d8\u30c6\u30ed\u306f1<span dir=\"auto\">\u03bcg\/ml\u524d\u5f8c\u3067\u3059\u306d\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306f\u7537\u602741\u540d\u30671.8\u00b10.6 \u03bcg\/ml\u3001\u5973\u602737\u540d\u30672.0\u00b10.5 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style=\"color: #3366ff;\">\u300cApolipoprotein composition of HDL in cholesteryl ester transfer protein deficiency\u300d<\/span><\/p>\n<p><span style=\"color: #3366ff;\">\u300c\u30b3\u30ec\u30b9\u30c6\u30ea\u30eb\u30a8\u30b9\u30c6\u30eb\u8ee2\u9001\u30bf\u30f3\u30d1\u30af\u8cea\u6b20\u640d\u75c7\u306b\u304a\u3051\u308bHDL\u306e\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u7d44\u6210\u300d\uff08\u539f\u6587\u306f<a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14657195\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5c02\u9580\u5bb6\u3068\u3044\u3046\u306e\u306f\u3001\u81ea\u5206\u306e\u77e5\u3063\u3066\u3044\u308b\u77e5\u8b58\u306e\u4e2d\u3067\u7269\u4e8b\u3092\u8aac\u660e\u3057\u3088\u3046\u3068\u3057\u307e\u3059\u3002\u81ea\u5206\u306e\u77e5\u8b58\u304c\u9593\u9055\u3063\u3066\u3044\u308b\u3068\u304b\u3001\u81ea\u5206\u306e\u77e5\u3063\u3066\u308b\u77e5\u8b58\u3067\u306f\u8aac\u660e\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u3042\u308b\u306a\u3069\u3068\u306f\u3042\u307e\u308a\u8003\u3048\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u533b\u5b66\u90e8\u3067\u7fd2\u3063\u305f\u3053\u3068\u304c\u6b63\u3057\u3044\u3068\u306f\u9650\u308a\u307e<\/p>\n","protected":false},"author":1,"featured_media":35811,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[8,145,111,146,155,144,148,10],"tags":[19,24,55,98],"class_list":["post-35808","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","category-ldl","category-111","category-hdl","category-cvd","category-cholesterol","category-fh","category-10","tag-toushitsuseigen","tag-cholesterol","tag-cvd","tag-98","two-columns"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/33694853_s-e1788344139131.jpg","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9cBot-9jy","jetpack-related-posts":[{"id":4182,"url":"https:\/\/promea2014.com\/blog\/?p=4182","url_meta":{"origin":35808,"position":0},"title":"\u6b8b\u5ff5\u306a\u304c\u3089\u73fe\u5728\u306e\u5185\u79d1\u5b66\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u72b6\u614b\u304c\u5927\u524d\u63d0\u3067\u3042\u308b","author":"Dr.Shimizu","date":"2018\u5e744\u670825\u65e5","format":false,"excerpt":"\u6c5f\u90e8\u5148\u751f\u306e\u30d6\u30ed\u30b0\u306b\u53d6\u308a\u4e0a\u3052\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u304c\uff08\u6c5f\u90e8\u5148\u751f\u306e\u8a18\u4e8b\u306f\u3053\u3053\uff09\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u5024\u3092\u793a\u2026","rel":"","context":"\u7cd6\u8cea\u5236\u9650","block_context":{"text":"\u7cd6\u8cea\u5236\u9650","link":"https:\/\/promea2014.com\/blog\/?cat=8"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/04\/1a8292b530cf279c7287a0e22a2e6bd4_s.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/04\/1a8292b530cf279c7287a0e22a2e6bd4_s.jpg?resize=350%2C200&ssl=1 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